CN103656079A - Patch for treating chilblains and preparation method thereof - Google Patents
Patch for treating chilblains and preparation method thereof Download PDFInfo
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- CN103656079A CN103656079A CN201210323565.4A CN201210323565A CN103656079A CN 103656079 A CN103656079 A CN 103656079A CN 201210323565 A CN201210323565 A CN 201210323565A CN 103656079 A CN103656079 A CN 103656079A
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- patch
- chilblain
- chilblains
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Abstract
The invention discloses a patch for treating chilblains and a preparation method thereof, aiming to solve the problem that drugs capable of effectively treating chilblains do not exist at present in the early period of chilblains infection. The patch for treating chilblains is prepared from the following components by weight: 10-15g of cassia twig, 5-10g of poria cocos, 5-10g of ligusticum wallichii, 3-5g of parasitic loranthus, 3-5g of liquorice, 3-8g of pubescent holly root, 6-9g of daphne genkwa, 6-8g of safflower, 5-15g of borneol and 5-10g of aloes. The patch is reasonable in formula and has good effects and good treatment effects on chilblains. In the early period of chilblains infection of patients, applied to infected parts, the patch can achieve the aims of promoting blood circulation and eliminating chilblains. Meanwhile, the patch can provide a protective layer for skins to prevent matters such as water from coming into contact with the surfaces of the skins, thus avoiding further deterioration of chilblains.
Description
Technical field
The present invention relates to field of medicaments, especially a kind of patch for the treatment of chilblain and preparation method thereof.
Background technology
Cold injury is multiple disease in a kind of winter, and it is under certain condition because cold acts on human body, causes part and even whole body damage.In most cases, part frozen shows as chilblain, and it is a kind of non-property freezed damage.Chilblain is mainly in the positions such as the back of the hand, finger, heel, ear.Infect after chilblain, skin surface there will be redness, and occurs the tuberosity that differs in size, and patient can feel distending pain, burns and itches unbearably, and skin surface is also conventionally with blister.The common endurable of patient burns and itches bitterly, can consciously or unconsciously to blister, scratch, thereby blister is broken.After blister ulceration, form table fester, ooze out serosity, the lighter is incrustation automatically, and severe patient may cause infection suppurates.
At present, the medicament for the treatment of chilblain is mainly to treat for chilblain morbidity formed table fester of later stage, after treatment, can form ugly crust.Infecting the chilblain initial stage, also there is no to carry out the effectively medicine for the treatment of at present, patient can only, by prevent the further deterioration of chilblain from may causing skin injury and firmly rub by mode warming or that firmly rub, cause secondary infection.Thereby, provide a kind of and infecting the chilblain initial stage, can effectively treat the medicine of chilblain, alleviate patient suffering, be main purpose of the present invention.
Summary of the invention
Goal of the invention of the present invention is: for the problem of above-mentioned existence, provide a kind of patch for the treatment of chilblain and preparation method thereof, patch formula of the present invention is reasonable, effective, can play good therapeutic effect to chilblain.Adopt patch of the present invention, at patient infection's chilblain initial stage, be affixed on affected part, can play blood circulation promoting, eliminate the object of chilblain.Meanwhile, patch itself also can, for the materials such as skin provides a protective layer, anti-sealing contact skin surface, avoid chilblain further to worsen.
The technical solution used in the present invention is as follows:
Treat a patch for chilblain, by the component of following weight portion, be prepared from: 10-15g Ramulus Cinnamomi, 5-10g Poria, 5-10g Rhizoma Chuanxiong, 3-5g Herba Taxilli, 3-5g Radix Glycyrrhizae, 3-8g Radix Ilicis Pubescentis, 6-9g Flos Genkwa, 6-8g Flos Carthami, 5-15g Borneolum Syntheticum, 5-10g Aloe.
As preferably, by the component of following weight portion, be prepared from: 12g Ramulus Cinnamomi, 6g Poria, 6g Rhizoma Chuanxiong, 5g Herba Taxilli, 5g Radix Glycyrrhizae, 8g Radix Ilicis Pubescentis, 8g Flos Genkwa, 8g Flos Carthami, 10g Borneolum Syntheticum, 8g Aloe.
The preparation method that is used for the patch of above-mentioned treatment chilblain, comprises the steps:
(1) by proportioning, take each component, Ramulus Cinnamomi, Poria, Herba Taxilli, Radix Glycyrrhizae, Radix Ilicis Pubescentis, Rhizoma Chuanxiong five kinds of Chinese medicine are decocted with water to twice, collect filtrate, be condensed into 20-50mL filtrate;
(2) in filtrate, add adjuvant again, stir, heating is endured to dripping into pearl tack-free, is immersed in the water, and makes just cream;
(3) first cream is dissolved, add wherein Flos Genkwa, Flos Carthami, Borneolum Syntheticum, the Aloe of having pulverized, stir, cooling, coat on cloth, obtain product;
Wherein, the filtrate quality sum that prepared by adjuvant, Flos Genkwa, Flos Carthami, Borneolum Syntheticum, Aloe and step (2) is 100g.
In described step (1), decoct with water for the first time 1-3h, decoct with water for the second time 2-5h.
In described step (2), adjuvant is Plumbum preparatium.
Medicine of the present invention has good function of promoting blood circulation to disperse blood clots, can promote local blood circulation, thereby chilblain is played to good therapeutic effect.Ramulus Cinnamomi in the present invention, Poria, Herba Taxilli, Radix Glycyrrhizae, Radix Ilicis Pubescentis, Rhizoma Chuanxiong five kinds of Chinese medicine have the effect of blood circulation and channel invigorating, are aided with Flos Genkwa, Flos Carthami, Borneolum Syntheticum, Aloe simultaneously, thereby can effectively treat chilblain.In Aloe of the present invention, contain 1-Hydroxy-1,2,3-propanetricarboxylic acid. calcium component, there is the effect of blood circulation promoting, expansion blood capillary, make unblocked blood flowing and be recycled to the tip of each blood capillary, thus strong blood circulation promoting.Meanwhile, in Aloe, also contain the materials such as wound hormone and polysaccharide peptide manna, there is viral infection resisting, promote the effect that wound healing restores.Therefore, the present invention can also treat the skin of slight fragmentation, and wound does not stay scar after curing completely.Meanwhile, the present invention is usingd Borneolum Syntheticum as carrier, and Borneolum Syntheticum itself has strong penetration, and other drug, can quick penetration skin surface under the effect of Borneolum Syntheticum, thus to chilblain carry out fast, effectively treatment.Between medicine of the present invention, there is the effect of Synergistic, by cooperatively interacting of each component, thereby reach better therapeutic effect.Meanwhile, the present invention has carried out differentiated treatment to different components.Five, Ramulus Cinnamomi, Poria etc. pass through to decoct, and effective ingredient is wherein oozed out completely, thereby guarantee its drug effect.Flos Genkwa, Flos Carthami, Borneolum Syntheticum, Aloe itself have good antiinflammation, thereby directly by its ground ingredients, not only have significant efficiency, have also reduced processing cost simultaneously.Processing technology of the present invention is simple, and prepared medication effect is good, can it effectively be treated in chilblain initial infection, significantly reduces patient suffering.Meanwhile, the effect of the blood circulation promoting that medicine of the present invention has, can be to a certain extent, and the secondary of anti-frostbite occurs.
The specific embodiment
Disclosed all features in this description, or the step in disclosed all methods or process, except mutually exclusive feature and/or step, all can combine by any way.
Disclosed arbitrary feature in this description, unless narration especially all can be replaced by other equivalences or the alternative features with similar object.That is,, unless narration especially, each feature is an example in a series of equivalences or similar characteristics.
Embodiment 1
Take respectively 10g Ramulus Cinnamomi, 6g Poria, 5g Rhizoma Chuanxiong, 3g Herba Taxilli, 3g Radix Glycyrrhizae, 5g Radix Ilicis Pubescentis, 6g Flos Genkwa, 8g Flos Carthami, 7g Borneolum Syntheticum, 10g Aloe, standby.Ramulus Cinnamomi, Poria, Herba Taxilli, Radix Glycyrrhizae, Radix Ilicis Pubescentis, Rhizoma Chuanxiong five kinds of Chinese medicine are decocted with water to twice, collect filtrate, filtrate is condensed into 50mL.In filtrate, add Plumbum preparatium again, stir, heating is endured to dripping into pearl tack-free, is immersed in the water, and makes just cream.Wherein, Plumbum preparatium, Flos Genkwa, Flos Carthami, Borneolum Syntheticum, Aloe and filtrate quality sum are 100g.First cream is dissolved, add wherein Flos Genkwa, Flos Carthami, Borneolum Syntheticum, the Aloe of having pulverized, stir, cooling, coat on cloth, obtain product.
Embodiment 2
Take respectively 15g Ramulus Cinnamomi, 9g Poria, 9g Rhizoma Chuanxiong, 5g Herba Taxilli, 4g Radix Glycyrrhizae, 6g Radix Ilicis Pubescentis, 8g Flos Genkwa, 6g Flos Carthami, 15g Borneolum Syntheticum, 6g Aloe, standby.Ramulus Cinnamomi, Poria, Herba Taxilli, Radix Glycyrrhizae, Radix Ilicis Pubescentis, Rhizoma Chuanxiong five kinds of Chinese medicine are decocted with water to twice, decoct with water for the first time 3h, filter, separated filtering residue, obtains filtrate for the first time; In filtering residue, decoct with water 5h again, filter, obtain filtrate for the second time, merging filtrate, is condensed into 20mL by filtrate.In filtrate, add Plumbum preparatium again, stir, heating is endured to dripping into pearl tack-free, is immersed in the water, and makes just cream.First cream is dissolved, add wherein Flos Genkwa, Flos Carthami, Borneolum Syntheticum, the Aloe of having pulverized, stir, cooling, coat on cloth, obtain product.
Embodiment 3
Take respectively 12g Ramulus Cinnamomi, 9g Poria, 9g Rhizoma Chuanxiong, 3g Herba Taxilli, 3g Radix Glycyrrhizae, 4g Radix Ilicis Pubescentis, 9g Flos Genkwa, 8g Flos Carthami, 9g Borneolum Syntheticum, 10g Aloe.Ramulus Cinnamomi, Poria, Herba Taxilli, Radix Glycyrrhizae, Radix Ilicis Pubescentis, Rhizoma Chuanxiong five kinds of Chinese medicine are decocted with water to twice, decoct with water for the first time 1.5h, filter, separated filtering residue, obtains filtrate for the first time; In filtering residue, decoct with water 2h again, filter, obtain filtrate for the second time, merging filtrate, is condensed into 25mL by filtrate.In filtrate, add Plumbum preparatium again, stir, heating is endured to dripping into pearl tack-free, is immersed in the water, and makes just cream.First cream is dissolved, add wherein Flos Genkwa, Flos Carthami, Borneolum Syntheticum, the Aloe of having pulverized, stir, cooling, coat on cloth, obtain product.
Embodiment 4
Take respectively 12g Ramulus Cinnamomi, 6g Poria, 6g Rhizoma Chuanxiong, 5g Herba Taxilli, 5g Radix Glycyrrhizae, 8g Radix Ilicis Pubescentis, 8g Flos Genkwa, 8g Flos Carthami, 10g Borneolum Syntheticum, 8g Aloe, standby.Ramulus Cinnamomi, Poria, Herba Taxilli, Radix Glycyrrhizae, Radix Ilicis Pubescentis, Rhizoma Chuanxiong five kinds of Chinese medicine are decocted with water to twice, decoct with water for the first time 2h, filter, separated filtering residue, obtains filtrate for the first time; In filtering residue, decoct with water 4h again, filter, obtain filtrate for the second time, merging filtrate, is condensed into 40mL by filtrate.In filtrate, add Plumbum preparatium again, stir, heating is endured to dripping into pearl tack-free, is immersed in the water, and makes just cream.First cream is dissolved, add wherein Flos Genkwa, Flos Carthami, Borneolum Syntheticum, the Aloe of having pulverized, stir, cooling, coat on cloth, obtain product.
Clinical experiment
Choose 10 patients, patient age average out to 14.6 years old, 3 male 7 female, patient all has chilblain patient for many years, and winter, finger, toe, auricle were easily got chilblains.
Using method
When patient feels that finger, toe, auricle are itched, patch of the present invention is affixed on to affected part, change every day one.After general transference cure, continue to paste three to five.When finding that finger, toe, auricle secondary are itched, repeat said process.
Therapeutic effect
In the test in a winter, there are 3 patients, use after patch of the present invention 2-4 time, there is not chilblain situation; There are 5 patients, use after patch of the present invention 5-8 time, do not occur chilblain situation; There are 2 patients, use after patch of the present invention, occurred redness, but the sense of not burning and itching unbearably, there is not breakage, the phenomenon of festering in skin.After tested, patch of the present invention has good therapeutic effect to chilblain.
The present invention is not limited to the aforesaid specific embodiment.The present invention expands to any new feature or any new combination disclosing in this manual, and the arbitrary new method disclosing or step or any new combination of process.
Claims (5)
1. treat a patch for chilblain, by the component of following weight portion, be prepared from: 10-15g Ramulus Cinnamomi, 5-10g Poria, 5-10g Rhizoma Chuanxiong, 3-5g Herba Taxilli, 3-5g Radix Glycyrrhizae, 3-8g Radix Ilicis Pubescentis, 6-9g Flos Genkwa, 6-8g Flos Carthami, 5-15g Borneolum Syntheticum, 5-10g Aloe.
2. treat according to claim 1 the patch of chilblain, it is characterized in that, by the component of following weight portion, be prepared from: 12g Ramulus Cinnamomi, 6g Poria, 6g Rhizoma Chuanxiong, 5g Herba Taxilli, 5g Radix Glycyrrhizae, 8g Radix Ilicis Pubescentis, 8g Flos Genkwa, 8g Flos Carthami, 10g Borneolum Syntheticum, 8g Aloe.
3. according to the preparation method for the treatment of the patch of chilblain described in claim 1 or 2, it is characterized in that, the preparation method for the patch of above-mentioned treatment chilblain, comprises the steps:
(1) by proportioning, take each component, Ramulus Cinnamomi, Poria, Herba Taxilli, Radix Glycyrrhizae, Radix Ilicis Pubescentis, Rhizoma Chuanxiong five kinds of Chinese medicine are decocted with water to twice, collect filtrate, be condensed into 20-50mL filtrate;
(2) in filtrate, add adjuvant again, stir, heating is endured to dripping into pearl tack-free, is immersed in the water, and makes just cream;
(3) first cream is dissolved, add wherein Flos Genkwa, Flos Carthami, Borneolum Syntheticum, the Aloe of having pulverized, stir, cooling, coat on cloth, obtain product;
Wherein, the filtrate quality sum that prepared by adjuvant, Flos Genkwa, Flos Carthami, Borneolum Syntheticum, Aloe and step (2) is 100g.
4. treat according to claim 3 the preparation method of the patch of chilblain, it is characterized in that, in described step (1), decoct with water for the first time 1-3h, decoct with water for the second time 2-5h.
5. treat according to claim 3 the preparation method of the patch of chilblain, it is characterized in that, in described step (2), adjuvant is Plumbum preparatium.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210323565.4A CN103656079A (en) | 2012-09-05 | 2012-09-05 | Patch for treating chilblains and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210323565.4A CN103656079A (en) | 2012-09-05 | 2012-09-05 | Patch for treating chilblains and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN103656079A true CN103656079A (en) | 2014-03-26 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210323565.4A Pending CN103656079A (en) | 2012-09-05 | 2012-09-05 | Patch for treating chilblains and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104274635A (en) * | 2014-09-25 | 2015-01-14 | 江苏奇力康皮肤药业有限公司 | Chilblain ointment and preparation method thereof |
| CN105412414A (en) * | 2015-12-05 | 2016-03-23 | 重庆市中药研究院 | Skin care hirudo nipponica composition and preparation method thereof |
-
2012
- 2012-09-05 CN CN201210323565.4A patent/CN103656079A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104274635A (en) * | 2014-09-25 | 2015-01-14 | 江苏奇力康皮肤药业有限公司 | Chilblain ointment and preparation method thereof |
| CN105412414A (en) * | 2015-12-05 | 2016-03-23 | 重庆市中药研究院 | Skin care hirudo nipponica composition and preparation method thereof |
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Application publication date: 20140326 |