CN103648282B - 噻唑化物类化合物用于预防和治疗病毒性疾病、癌症和由细胞内感染引起的疾病的用途 - Google Patents
噻唑化物类化合物用于预防和治疗病毒性疾病、癌症和由细胞内感染引起的疾病的用途 Download PDFInfo
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611145115.5A CN107096032A (zh) | 2011-05-16 | 2012-05-15 | 在有需要的对象中刺激免疫应答的方法 |
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| US201161486728P | 2011-05-16 | 2011-05-16 | |
| US61/486,728 | 2011-05-16 | ||
| PCT/US2012/037958 WO2012158699A1 (en) | 2011-05-16 | 2012-05-15 | Use of thiazolide compounds for the prevention and treatment of viral diseases, cancer and diseases caused by intracellular infections |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611145115.5A Division CN107096032A (zh) | 2011-05-16 | 2012-05-15 | 在有需要的对象中刺激免疫应答的方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103648282A CN103648282A (zh) | 2014-03-19 |
| CN103648282B true CN103648282B (zh) | 2017-02-15 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| CN201280035142.0A Expired - Fee Related CN103648282B (zh) | 2011-05-16 | 2012-05-15 | 噻唑化物类化合物用于预防和治疗病毒性疾病、癌症和由细胞内感染引起的疾病的用途 |
| CN201611145115.5A Pending CN107096032A (zh) | 2011-05-16 | 2012-05-15 | 在有需要的对象中刺激免疫应答的方法 |
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| CN201611145115.5A Pending CN107096032A (zh) | 2011-05-16 | 2012-05-15 | 在有需要的对象中刺激免疫应答的方法 |
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| EP (1) | EP2709453B1 (https=) |
| JP (3) | JP6138764B2 (https=) |
| KR (1) | KR102037162B1 (https=) |
| CN (2) | CN103648282B (https=) |
| AU (1) | AU2012255962B2 (https=) |
| BR (1) | BR112013029505A2 (https=) |
| CA (1) | CA2836253C (https=) |
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| ZA (1) | ZA201308617B (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103648282B (zh) * | 2011-05-16 | 2017-02-15 | 罗马克实验室有限公司 | 噻唑化物类化合物用于预防和治疗病毒性疾病、癌症和由细胞内感染引起的疾病的用途 |
| WO2014145631A1 (en) * | 2013-03-15 | 2014-09-18 | The Broad Institute, Inc. | Dendritic cell response gene expression, compositions of matters and methods of use thereof |
| KR101508611B1 (ko) | 2013-09-02 | 2015-04-08 | 가톨릭대학교 산학협력단 | 아파티닙을 포함하는 톡소포자충 감염증의 예방 및 치료용 조성물 |
| KR101508610B1 (ko) * | 2013-09-02 | 2015-04-08 | 가톨릭대학교 산학협력단 | 다코미티닙을 포함하는 톡소포자충 감염증의 예방 및 치료용 조성물 |
| WO2015030504A1 (ko) * | 2013-09-02 | 2015-03-05 | 가톨릭대학교 산학협력단 | 비소세포폐암 치료제를 유효성분으로 포함하는 톡소포자충감염증의 예방 또는 치료용 약학 조성물 |
| CN107105660A (zh) | 2014-11-11 | 2017-08-29 | 罗马克实验室有限公司 | 使用替唑尼特、其类似物或盐的前药的治疗组合物和治疗方法 |
| WO2016123073A1 (en) | 2015-01-26 | 2016-08-04 | Children's Medical Center Corporation | Treatment of infectious diseases |
| CN108289961A (zh) | 2016-03-31 | 2018-07-17 | 罗马克实验室有限公司 | 用于治疗病毒性感染的噻唑化物化合物 |
| EA202191466A1 (ru) | 2016-04-11 | 2021-12-31 | Женфит | Способы лечения холестатических и фибротических заболеваний |
| CN105998036B (zh) * | 2016-05-19 | 2018-07-27 | 洛阳市兽药厂 | 一种猪禽用复方磺胺硝唑尼特可溶性粉 |
| US11173149B2 (en) | 2017-04-18 | 2021-11-16 | Romark Laboratories L.C. | Inhibition of protein disulfide-isomerase A3 |
| JP7365054B2 (ja) * | 2017-11-17 | 2023-10-19 | ケスター,ヒューバート | リンパ管平滑筋腫症及びその他の疾患に使用するための[2-[(5-ニトロ-1,3-チアゾール-2-イル)カルバモイル]フェニル]エタノエート |
| CA3130518A1 (en) * | 2019-04-12 | 2020-10-15 | Nicolas STANKOVIC-VALENTIN | Nitazoxanide and thiazolides for use in the treatment of diseases associated with oxidative stress |
| CN118903087A (zh) | 2019-07-26 | 2024-11-08 | 埃斯佩尔维塔治疗股份有限公司 | 可用于预防或治疗疾病的官能化的长链烃一元和二元羧酸 |
| CN113398125B (zh) | 2020-03-16 | 2024-05-03 | 绍兴君科臻元医药科技有限公司 | 替唑尼特药物组合物及其医药用途 |
| EP4182304A1 (en) | 2020-07-20 | 2023-05-24 | Romark Laboratories, L.C. | Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine |
| MX2023002208A (es) | 2020-08-24 | 2023-05-17 | Romark Laboratories Lc | Uso de tiazolidas contra los coronavirus. |
| CA3209453A1 (en) | 2021-01-25 | 2022-07-28 | Espervita Therapeutics, Inc. | Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives therof, and their use for the prevention or treatment of disease |
| US11730712B2 (en) | 2021-01-25 | 2023-08-22 | Espervita Therapeutics, Inc. | Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease |
| WO2023077711A1 (zh) * | 2021-11-03 | 2023-05-11 | 南方科技大学 | 预防前列腺癌的药剂的筛选方法及硝唑尼特在制药中的应用 |
| CN114231611A (zh) * | 2021-12-07 | 2022-03-25 | 中南大学湘雅二医院 | 干扰素诱导基因ifit3对b淋巴细胞活化及分化影响的研究方法 |
| CN116539887A (zh) * | 2023-01-09 | 2023-08-04 | 重庆医科大学 | Psme1作为药物靶点在筛选或制备治疗乙型肝炎的药物中的应用 |
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| US9439878B2 (en) * | 2010-06-03 | 2016-09-13 | Douglas Tyler McKenzie | Use of lumefantrine and related compounds in the treatment of cancer |
| EP2725902A4 (en) * | 2011-04-06 | 2015-06-24 | Univ Princeton | ANTIVIRAL COMBINATION THERAPY |
| CN103648282B (zh) * | 2011-05-16 | 2017-02-15 | 罗马克实验室有限公司 | 噻唑化物类化合物用于预防和治疗病毒性疾病、癌症和由细胞内感染引起的疾病的用途 |
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| US5965590A (en) * | 1994-09-08 | 1999-10-12 | Romark Lab Lc | Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide |
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| KR20140028034A (ko) | 2014-03-07 |
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| US20190291404A1 (en) | 2019-09-26 |
| JP2014513725A (ja) | 2014-06-05 |
| MX2013013115A (es) | 2014-02-27 |
| US10814612B2 (en) | 2020-10-27 |
| IL229459B (en) | 2021-05-31 |
| JP6138764B2 (ja) | 2017-05-31 |
| EA024063B1 (ru) | 2016-08-31 |
| US10336058B2 (en) | 2019-07-02 |
| CA2836253A1 (en) | 2012-11-22 |
| MX378726B (es) | 2025-03-11 |
| US20180126722A1 (en) | 2018-05-10 |
| EP2709453A1 (en) | 2014-03-26 |
| EA201391616A1 (ru) | 2014-05-30 |
| WO2012158699A1 (en) | 2012-11-22 |
| CN103648282A (zh) | 2014-03-19 |
| ZA201308617B (en) | 2020-07-29 |
| JP2019052175A (ja) | 2019-04-04 |
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