CN103638470B - A kind of control motion sickness Chinese medicine patch - Google Patents
A kind of control motion sickness Chinese medicine patch Download PDFInfo
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- CN103638470B CN103638470B CN201310691050.4A CN201310691050A CN103638470B CN 103638470 B CN103638470 B CN 103638470B CN 201310691050 A CN201310691050 A CN 201310691050A CN 103638470 B CN103638470 B CN 103638470B
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Abstract
The present invention relates to control motion sickness Chinese medicine patch, can effectively solve existing drug side effect large, take inconvenient problem, its technical scheme solved is, this Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 8-20g, Garden lavender 3-10g, Bulbus Lilii 10-30g, Cortex Albiziae 8-20g, Flos Magnoliae 3-10g, Radix Angelicae Dahuricae 9-20g, Radix Curcumae 8-20g, FLOS MUME 3-10g, Fructus Citri Sarcodactylis 8-20g, Rhizoma Alpiniae Officinarum 8-20g and Rhizoma Acori Graminei 5-20g makes, the present invention has good anti-motion sickness curative effect, and make simple, low price, result of use is good, it is the innovation on motion sickness agent thing.
Description
Technical field
The present invention relates to medicine, particularly a kind of control motion sickness Chinese medicine patch.
Background technology
Motion sickness is also known as motion sickness, that body is subject to the stimulation of unfavorable movement environment (as by bus, by ship, by air, by plane) and the syndrome that causes, cardinal symptom is dizziness, Nausea and vomiting, be in a cold sweat, pale complexion, nervous, cold limbs, lethargy, have a strong impact on work and life, making troubles and misery to the trip of patient, is common clinical and frequently-occurring disease.Its sickness rate is on the rise in recent years, and the whole world about has the Genus Homo of 1/3 easily to send out body constitution in motion sickness.Control motion sickness commonly uses Western medicine, as antihistaminic, anticholinergic agent, sympatheticomimetic, central depressant etc., has better effects, but mostly has the apparent side effects such as drowsiness, dizzy, xerostomia.Compared to Western medicine, Chinese medicine is to adjust body integrality, few side effects for significant advantage.And than extract oral agent, Chinese medicine patch uses more convenient, more easy for patients to accept.Therefore, the development of novel anti-motion sickness Chinese medicine patch becomes the problem that urgent clinical needs solve.
Summary of the invention
For above-mentioned situation, for solving the defect of prior art, the object of the present invention is just to provide a kind of control motion sickness Chinese medicine patch, effectively can solve existing drug side effect large, take inconvenient problem.
The technical scheme that the present invention solves is, this Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 8-20g, Garden lavender 3-10g, Bulbus Lilii 10-30g, Cortex Albiziae 8-20g, Flos Magnoliae 3-10g, Radix Angelicae Dahuricae 9-20g, Radix Curcumae 8-20g, FLOS MUME 3-10g, Fructus Citri Sarcodactylis 8-20g, Rhizoma Alpiniae Officinarum 8-20g and Rhizoma Acori Graminei 5-20g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 1500-2000ml for the first time, soak 1-2h, after boiling, slow fire boiling 15-30min again, filter, obtain first time filtrate, medicinal residues add the water of 1500-2000ml again, after boiling, slow fire boiling 15-30min, filter, obtain second time filtrate, merge twice filtrate, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 1-2 hour, gauze or alternate products are taken out, dry under room temperature, cutting patent medicine gauze piece or alternate products block, be placed on medicinal adhesive plaster, protective mulch on medicine gauze piece or alternate products block, obtain.
The present invention can make with pharmaceutically acceptable adjuvant the transdermal preventing and treating motion sickness and paste.
The present invention has good anti-motion sickness curative effect, and makes simple, and low price, result of use is good, is the innovation on motion sickness agent thing.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is described in further detail.
Embodiment 1
This Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 10g, Garden lavender 10g, Bulbus Lilii 20g, Cortex Albiziae 15g, Flos Magnoliae 10g, Radix Angelicae Dahuricae 10g, Radix Curcumae 15g, FLOS MUME 10g, Fructus Citri Sarcodactylis 15g Rhizoma Alpiniae Officinarum 15g and Rhizoma Acori Graminei 15g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 2000ml for the first time, soak 1.5h, after boiling, slow fire boiling 25min again, filter, obtain first time filtrate, medicinal residues add the water of 2000ml again, after boiling, slow fire boiling 25min, filter, obtain second time filtrate, merge twice medicinal liquid, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 2 hours, gauze or alternate products are taken out, dry under room temperature, cut into 2 × 2cm medicine gauze piece or alternate products block, again medicine gauze piece or alternate products block are affixed on long 8cm, in the middle of the adhesive plaster of wide 3cm, on medicine gauze piece or alternate products block, covered with plastic film does protective layer, be placed between adhesive plaster and protective layer by medicine gauze piece or alternate products block, obtain.
Embodiment 2
This Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 8g, Garden lavender 3g, Bulbus Lilii 10g, Cortex Albiziae 8g, Flos Magnoliae 3g, Radix Angelicae Dahuricae 9g, Radix Curcumae 8g, FLOS MUME 3g, Fructus Citri Sarcodactylis 8g, Rhizoma Alpiniae Officinarum 8g and Rhizoma Acori Graminei 5g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, the water that first time adds 1500ml, soak 1h, after boiling, then slow fire boiling 15min, filter, obtain first time filtrate, medicinal residues add the water of 1500ml again, after boiling, slow fire boiling 15min, filter, obtain second time filtrate, merge twice medicinal liquid, be concentrated into 500ml, the medicinal liquid that must concentrate, immerses 200g gauze or alternate products in medicinal liquid, soaks 1 hour, gauze or alternate products are taken out, dry under room temperature, cut into 2 × 2cm medicine gauze piece or alternate products block, then medicine gauze piece or alternate products block are affixed on long 8cm, in the middle of the adhesive plaster of wide 3cm, on medicine gauze piece or alternate products block, covered with plastic film does protective layer, is placed between adhesive plaster and protective layer, obtains final product by medicine gauze piece or alternate products block.
Embodiment 3
This Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 20g, Garden lavender 10g, Bulbus Lilii 30g, Cortex Albiziae 20g, Flos Magnoliae 10g, Radix Angelicae Dahuricae 20g, Radix Curcumae 20g, FLOS MUME 10g, Fructus Citri Sarcodactylis 20g, Rhizoma Alpiniae Officinarum 20g and Rhizoma Acori Graminei 20g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 2000ml for the first time, soak 1.5h, after boiling, slow fire boiling 25min again, filter, obtain first time filtrate, medicinal residues add the water of 2000ml again, after boiling, slow fire boiling 25min, filter, obtain second time filtrate, merge twice medicinal liquid, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 2 hours, gauze or alternate products are taken out, dry under room temperature, cut into 2 × 2cm medicine gauze piece or alternate products block, again medicine gauze piece or alternate products block are affixed on long 8cm, in the middle of the adhesive plaster of wide 3cm, on medicine gauze piece or alternate products block, covered with plastic film does protective layer, be placed between adhesive plaster and protective layer by medicine gauze piece or alternate products block, obtain.
Embodiment 4
This Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 8-14g, Garden lavender 3-6g, Bulbus Lilii 10-20g, Cortex Albiziae 8-14g, Flos Magnoliae 3-6g, Radix Angelicae Dahuricae 9-14g, Radix Curcumae 8-14g, FLOS MUME 3-6g, Fructus Citri Sarcodactylis 8-14g, Rhizoma Alpiniae Officinarum 8-14g and Rhizoma Acori Graminei 5-12g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 1500-1700ml for the first time, soak 1-2h, after boiling, slow fire boiling 15-30min again, filter, obtain first time filtrate, medicinal residues add the water of 1500-1700ml again, after boiling, slow fire boiling 15-30min, filter, obtain second time filtrate, merge twice medicinal liquid, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 1-2 hour, gauze or alternate products are taken out, dry under room temperature, cutting patent medicine gauze piece or alternate products block, be placed on medicinal adhesive plaster, protective mulch on medicine gauze piece or alternate products block, obtain.
Embodiment 5
This Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 15-20g, Garden lavender 7-10g, Bulbus Lilii 21-30g, Cortex Albiziae 15-20g, Flos Magnoliae 7-10g, Radix Angelicae Dahuricae 15-20g, Radix Curcumae 15-20g, FLOS MUME 7-10g, Fructus Citri Sarcodactylis 15-20g, Rhizoma Alpiniae Officinarum 15-20g and Rhizoma Acori Graminei 13-20g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 1800-2000ml for the first time, soak 1-2h, after boiling, slow fire boiling 15-30min again, filter, obtain first time filtrate, medicinal residues add the water of 1800-2000ml again, after boiling, slow fire boiling 15-30min, filter, obtain second time filtrate, merge twice medicinal liquid, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 1-2 hour, gauze or alternate products are taken out, dry under room temperature, cutting patent medicine gauze piece or alternate products block, be placed on medicinal adhesive plaster, protective mulch on medicine gauze piece or alternate products block, obtain.
When the present invention uses, throw off protective layer, with the moistening gauze of water, gauze is placed in umbilicus portion, is affixed on skin by adhesive plaster.The traditional Chinese medical science generally believes that motion sickness is relevant with " cold syndrome of the stomach dampness, disorder of movement of QI ", during outbreak, " qi-movement disturbance, disturbing the mind upwards ".In addition, this sick onset is rapid, disappears also fast, seemingly has the characteristic of " wind "." all wind trembling and dizziness, all belong to liver ", therefore this onste is also relevant with " incoordination between the liver and stomach ", the present invention selects Rhizoma Alpiniae Officinarum, Rhizoma Acori Graminei, the Herba Pogostemonis of warming middle-JIAO for eliminating dampness; Dispersing the stagnated liver-QI for regulating the stomach, the Radix Curcumae of regulating the flow of vital energy, FLOS MUME, Fructus Citri Sarcodactylis; The Radix Angelicae Dahuricae of dispelling wind, Flos Magnoliae, the Bulbus Lilii of clearing away heart-fire for tranquillization, lavandula angustifolia, Cortex Albiziae.All medicines play removing dampness stomach warming, expelling wind and cold altogether, have one's ideas straightened out calm the nerves, the merit of harmonizing the liver and stomach.
The efficient combination of medicine of the present invention, inner disease outer treat, achieve satisfied effect through test, related tests data is as follows:
anti-motion sickness clinical experimental data:
1, physical data
This group case 96 example, all meet motion sickness diagnostic criteria, all cases is all according to " otology " [Jiang Sichang, Gu Min, Wang Zhengmin. otology [M] .2 version. Shanghai: Shanghai science tech publishing house, 2002:992-993.] in diagnosis, case selection standard.Patient is divided into two groups at random, treatment group 49 example, wherein man 25 example, female 24 example; Year mean age (35.6 ± 5.9); Matched group 47 example, wherein man 24 example, female 23 example; Year mean age (35.1 ± 6.2).
, therapeutic scheme
Treatment group is affixed on umbilicus in first 30 minutes by bus after moistening for Chinese medicine patch of the present invention; Matched group dimenhydrinate tablets (Nanjing Bai Jingyu pharmaceutical factory) is oral, each 50mg, decoction being taken at a draught in 30min before riding public transportation means.All after leaving the vehicles, evaluate curative effect for two groups, riding time >=2h.
3, criterion of therapeutical effect
Reference literature [Tian Hua, Gu little Xia, Xu Yan, to swoon the peaceful cream treatment routine clinical observation of motion sickness 92 [J] etc. Tian Shi, the Hebei traditional Chinese medical science, 2004,26(6): 417-418] criterion of therapeutical effect.1. whole process is more comfortable, without dizzy, Nausea and vomiting symptom, has obvious appetite person, remembers 20 points; 2. omnidistance without Nausea and vomiting symptom, but sense gastral cavilty does not relax, and appetite does not slightly subtract person, remembers 15 points; 3. whole process has nausea but does not vomit, and without appetite person, remembers 8 points; 4. omnidistance vomiting >=3 persons count 0 point, 2 times persons and remember that 1 point, 1 time person remembers 2 points; 5. omnidistancely remember 2 points again with dizzy, weak, sleepy, excessive saliva, sialorrhea, perspiration or pale complexion, the 1-3 item person such as uncomfortable in chest, nervous, more than 3 persons remember 5 points again.Effective: integration >=15 point; Effective: integration >=10 point; Weak effect: integration >=5 point; Invalid: integration <5 divides.
, experimental result
Result shows, and treatment group obvious effective rate is 36.73%, and total effective rate reaches 97.96%, specifically in table 1.
table 1 liang group Clinical efficacy comparison
| Group | Number of cases | Effective | Effectively | Weak effect | Invalid | Obvious effective rate (%) | Total effective rate (%) |
| Matched group | 47 | 10 | 15 | 8 | 14 | 21.28 | 70.21 |
| Treatment group | 49 | 18 | 19 | 11 | 1 | 36.73 | 97.96 |
5, conclusion
To sum up, the present invention has good anti-motion sickness curative effect, and total effective rate reaches more than 97%, and makes simple, and low price, result of use is good, is the innovation on motion sickness agent thing, has good economic and social benefit.
Claims (6)
1. a control motion sickness Chinese medicine patch, it is characterized in that, this Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 8-20g, Garden lavender 3-10g, Bulbus Lilii 10-30g, Cortex Albiziae 8-20g, Flos Magnoliae 3-10g, Radix Angelicae Dahuricae 9-20g, Radix Curcumae 8-20g, FLOS MUME 3-10g, Fructus Citri Sarcodactylis 8-20g, Rhizoma Alpiniae Officinarum 8-20g and Rhizoma Acori Graminei 5-20g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 1500-2000ml for the first time, soak 1-2h, after boiling, slow fire boiling 15-30min again, filter, obtain first time filtrate, medicinal residues add the water of 1500-2000ml again, after boiling, slow fire boiling 15-30min, filter, obtain second time filtrate, merge twice filtrate, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 1-2 hour, gauze or alternate products are taken out, dry under room temperature, cutting patent medicine gauze piece or alternate products block, be placed on medicinal adhesive plaster, protective mulch on medicine gauze piece or alternate products block, obtain.
2. control motion sickness Chinese medicine patch according to claim 1, it is characterized in that, this Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 10g, Garden lavender 10g, Bulbus Lilii 20g, Cortex Albiziae 15g, Flos Magnoliae 10g, Radix Angelicae Dahuricae 10g, Radix Curcumae 15g, FLOS MUME 10g, Fructus Citri Sarcodactylis 15g, Rhizoma Alpiniae Officinarum 15g and Rhizoma Acori Graminei 15g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 2000ml for the first time, soak 1.5h, after boiling, slow fire boiling 25min again, filter, obtain first time filtrate, medicinal residues add the water of 2000ml again, after boiling, slow fire boiling 25min, filter, obtain second time filtrate, merge twice medicinal liquid, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 2 hours, gauze or alternate products are taken out, dry under room temperature, cut into 2 × 2cm medicine gauze piece or alternate products block, again medicine gauze piece or alternate products block are affixed on long 8cm, in the middle of the adhesive plaster of wide 3cm, on medicine gauze piece or alternate products block, covered with plastic film does protective layer, be placed between adhesive plaster and protective layer by medicine gauze piece or alternate products block, obtain.
3. control motion sickness Chinese medicine patch according to claim 1, it is characterized in that, this Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 8g, Garden lavender 3g, Bulbus Lilii 10g, Cortex Albiziae 8g, Flos Magnoliae 3g, Radix Angelicae Dahuricae 9g, Radix Curcumae 8g, FLOS MUME 3g, Fructus Citri Sarcodactylis 8g, Rhizoma Alpiniae Officinarum 8g and Rhizoma Acori Graminei 5g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 1500ml for the first time, soak 1h, after boiling, slow fire boiling 15min again, filter, obtain first time filtrate, medicinal residues add the water of 1500ml again, after boiling, slow fire boiling 15min, filter, obtain second time filtrate, merge twice medicinal liquid, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 1 hour, gauze or alternate products are taken out, dry under room temperature, cut into 2 × 2cm medicine gauze piece or alternate products block, again medicine gauze piece or alternate products block are affixed on long 8cm, in the middle of the adhesive plaster of wide 3cm, on medicine gauze piece or alternate products block, covered with plastic film does protective layer, be placed between adhesive plaster and protective layer by medicine gauze piece or alternate products block, obtain.
4. control motion sickness Chinese medicine patch according to claim 1, it is characterized in that, this Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 20g, Garden lavender 10g, Bulbus Lilii 30g, Cortex Albiziae 20g, Flos Magnoliae 10g, Radix Angelicae Dahuricae 20g, Radix Curcumae 20g, FLOS MUME 10g, Fructus Citri Sarcodactylis 20g, Rhizoma Alpiniae Officinarum 20g and Rhizoma Acori Graminei 20g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 2000ml for the first time, soak 1.5h, after boiling, slow fire boiling 25min again, filter, obtain first time filtrate, medicinal residues add the water of 2000ml again, after boiling, slow fire boiling 25min, filter, obtain second time filtrate, merge twice medicinal liquid, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 2 hours, gauze or alternate products are taken out, dry under room temperature, cut into 2 × 2cm medicine gauze piece or alternate products block, again medicine gauze piece or alternate products block are affixed on long 8cm, in the middle of the adhesive plaster of wide 3cm, on medicine gauze piece or alternate products block, covered with plastic film does protective layer, be placed between adhesive plaster and protective layer by medicine gauze piece or alternate products block, obtain.
5. control motion sickness Chinese medicine patch according to claim 1, it is characterized in that, this Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 8-14g, Garden lavender 3-6g, Bulbus Lilii 10-20g, Cortex Albiziae 8-14g, Flos Magnoliae 3-6g, Radix Angelicae Dahuricae 9-14g, Radix Curcumae 8-14g, FLOS MUME 3-6g, Fructus Citri Sarcodactylis 8-14g, Rhizoma Alpiniae Officinarum 8-14g and Rhizoma Acori Graminei 5-12g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 1500-1700ml for the first time, soak 1-2h, after boiling, slow fire boiling 15-30min again, filter, obtain first time filtrate, medicinal residues add the water of 1500-1700ml again, after boiling, slow fire boiling 15-30min, filter, obtain second time filtrate, merge twice medicinal liquid, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 1-2 hour, gauze or alternate products are taken out, dry under room temperature, cutting patent medicine gauze piece or alternate products block, be placed on medicinal adhesive plaster, protective mulch on medicine gauze piece or alternate products block, obtain.
6. control motion sickness Chinese medicine patch according to claim 1, it is characterized in that, this Chinese medicine patch is by the material medicine of following weighing scale: Herba Pogostemonis 15-20g, Garden lavender 7-10g, Bulbus Lilii 21-30g, Cortex Albiziae 15-20g, Flos Magnoliae 7-10g, Radix Angelicae Dahuricae 15-20g, Radix Curcumae 15-20g, FLOS MUME 7-10g, Fructus Citri Sarcodactylis 15-20g, Rhizoma Alpiniae Officinarum 15-20g and Rhizoma Acori Graminei 13-20g makes, wherein, by above-mentioned raw materials medicament mixed together, decoct twice, add the water of 1800-2000ml for the first time, soak 1-2h, after boiling, slow fire boiling 15-30min again, filter, obtain first time filtrate, medicinal residues add the water of 1800-2000ml again, after boiling, slow fire boiling 15-30min, filter, obtain second time filtrate, merge twice medicinal liquid, be concentrated into 500ml, the medicinal liquid that must concentrate, 200g gauze or alternate products are immersed in medicinal liquid, soak 1-2 hour, gauze or alternate products are taken out, dry under room temperature, cutting patent medicine gauze piece or alternate products block, be placed on medicinal adhesive plaster, protective mulch on medicine gauze piece or alternate products block, obtain.
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| CN201310691050.4A CN103638470B (en) | 2013-12-17 | 2013-12-17 | A kind of control motion sickness Chinese medicine patch |
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| CN201310691050.4A CN103638470B (en) | 2013-12-17 | 2013-12-17 | A kind of control motion sickness Chinese medicine patch |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1082411A (en) * | 1992-08-01 | 1994-02-23 | 辽宁中山福利卫生用品工贸公司 | A kind of medicine for external use of preventing and treating motion sickness and preparation method thereof |
| CN101181621A (en) * | 2007-11-30 | 2008-05-21 | 何卫华 | Chinese medicine paste for preventing and controlling carsickness |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1082411A (en) * | 1992-08-01 | 1994-02-23 | 辽宁中山福利卫生用品工贸公司 | A kind of medicine for external use of preventing and treating motion sickness and preparation method thereof |
| CN101181621A (en) * | 2007-11-30 | 2008-05-21 | 何卫华 | Chinese medicine paste for preventing and controlling carsickness |
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