CN103638268A - Qiqing baidu drink and preparation method thereof - Google Patents

Qiqing baidu drink and preparation method thereof Download PDF

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Publication number
CN103638268A
CN103638268A CN201310650552.2A CN201310650552A CN103638268A CN 103638268 A CN103638268 A CN 103638268A CN 201310650552 A CN201310650552 A CN 201310650552A CN 103638268 A CN103638268 A CN 103638268A
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CN
China
Prior art keywords
drink
aloe
internal heat
qiqing
baidu
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Pending
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CN201310650552.2A
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Chinese (zh)
Inventor
卢建平
吴美华
栾军
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Zhenjiang Tianhe Biotechnology Co Ltd
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Zhenjiang Tianhe Biotechnology Co Ltd
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Priority to CN201310650552.2A priority Critical patent/CN103638268A/en
Publication of CN103638268A publication Critical patent/CN103638268A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a veterinary drug 'Qiqing baidu drink', which is characterized in that 1000ml of the Qiqing baidu drink is prepared from the following raw materials by weight: 180-220g of indigo naturalis, 150-180g of Polygonum cuspidatum, 100-150g of aloe, 75-100g of honeysuckle, 120-160g of radix gentianae, 30-60g of Platycodon grandiflorum and 200-300g of gypsum. The preparation method comprises the following steps of: processing the seven Chinese medicines in prescription, decocting the medicines in water for two times except for the aloe, decocting for 2 hours for the first time, decocting for 1 hour for the second time after adding the aloe, combining the decoction, filtering, concentrating the filtrate to about 900ml, cooling naturally, regulating pH to 5.5-6.5, filtering, diluting filtrate with water to 100ml, sterilizing and potting, thereby obtaining the product. The 'Qiqing baidu drink' prepared according to the invention is used for treating pig toxic heat, and total effective rate is more than 60%.

Description

Seven relieve internal heat clearly drinks and preparation method thereof
Technical field
The present invention relates to medicine field for animals, be specially a kind of oral preparation of Chinese traditional medicinal that is used for the treatment of pig pyretic toxicity card " seven relieve internal heat clearly drink " and preparation method thereof.
Background technology
In modern intensive breeding production, due to the biological characteristics of pig, add complex environment factor impact, easily experience heresy of pyretic toxicity and heating poison is demonstrate,proved.Affected pig presents high heat (more than 40 ℃), dyspnea, and tachypnea is breathed heavily slightly, and diet subtracts greatly or is absolutely useless, thirst and liking drink cold water; Skin and visual mucosa are rubescent, and the later stage is aubergine, and can see obvious petechia; The sick pig of part shows as watery nasal discharge, discharge of eye increases, and part pig has tear speckle; Constipation or diarrhoea; The course of disease is slightly long, and the sick pig of part shows as rear myasthenia of limbs, does not rise sleepingly; Cuing open the visible typical septicemia of inspection changes.Lymph nodes of body as a whole edema; Larynx, tracheal mucosa hyperemia or hemorrhage, be full of a large amount of mucus or foam in trachea, pulmonary edema, and lung is aubergine, part pig visible " carnification " or " pancreas change "; There are suppuration kitchen range, petechia in the dead Pulmonis Sus domestica portion that the course of disease is long, is great Ye or hemorrhagic pneumonia, diffuse interstitial pneumonia, the pathological changes such as fibrinous pleurisy, peritonitis, pericarditis; Heart hat fat and intracardiac adventitia have petechia; Renomegaly, congestion, there is petechia on some surfaces, are brown or khaki, the more crisp or deliquescing of quality; Liver is khaki, and matter is crisp, and there is necrosis region on surface, gallbladder swelling, and bile is dense thick; Part Gaster Sus domestica intestinal mucosa is congested, hemorrhage, edema, ulcer.
Sickness rate and the fatality rate of pyretic toxicity card are all higher, and many pig farms surpass 50%, bring huge economic loss, thereby caused the great attention of relevant departments to pig industry.Yet Etiology survey has shown Various Complex factor, make us being difficult to final conclusion.Use antibiotic, antiserum etc. usually to produce little effect, some units are used this disease of antibiotic therapy, not only can not mitigate the disease, and also it is dead obviously to accelerate disease pig.
Summary of the invention
That technical problem solved by the invention is to provide is a kind of " seven relieve internal heat clearly drink " and preparation method thereof, to solve the problem in background technology.
Technical problem to be solved by this invention realizes by the following technical solutions:
" seven relieve internal heat clearly drink " by weight, raw material is composed as follows: Indigo Naturalis 180~220g, Rhizoma Polygoni Cuspidati 150~180g, Aloe 100~150g, Flos Lonicerae 75~100g, Radix Gentianae 120~160g, Radix Platycodonis 30~60g, Gypsum Fibrosum 200~300g, make 1000ml.
By following processing step and technological parameter, prepare: above seven tastes, except Aloe, decoct with water twice, 2 hours for the first time, add for the second time Aloe to decoct 1 hour, collecting decoction, filter, filtrate is concentrated into about 900ml, lets cool, and regulates pH 5.5~6.5, filter, filtrate is diluted with water to 100ml, sterilizing, embedding and get final product.
In the present invention, raw material composition is preferably by weight: Indigo Naturalis 200g, Rhizoma Polygoni Cuspidati 160g, Aloe 120g, Flos Lonicerae 80g, Radix Gentianae 150g, Radix Platycodonis 50g, Gypsum Fibrosum 240g, make 1000ml.Every 100ml " seven relieve internal heat clearly drink " is equivalent to crude drug in whole 100g.
The present invention " seven relieve internal heat clearly drink " is sepia thick liquid, and gas is fragrant.There is heat-clearing and toxic substances removing, circulation of qi promoting intestinal stasis relieving, for the treatment of pig pyretic toxicity card.
The present invention " seven relieve internal heat clearly drink " using method is: gavages, and pig, every kg body weight 0.4ml, every day 2 times, is used in conjunction 5 days.
In side, seven kinds of medicines all have inhibition and killing action in various degree to various bacterial cause of disease, can effectively prevent and treat the secondary infection of antibacterial.Above-mentioned seven kinds of Chinese medicines are with proper proportion prescription, through extracting, filter, concentrated making " seven relieve internal heat clearly drink ", confirm that it demonstrate,proves curative effect to pig pyretic toxicity certain through clinical trial.
Clinical test results of the present invention is as follows: select 120 of pyretic toxicity card affected pigs, be divided at random 4 groups.Test high, medium and low dosage group and by the dosage of every kg body weight 0.4,0.2,0.1 ml, gavage " seven relieve internal heat clearly drink " respectively, the doxycycline hydrochloride soluble powder administration of drinking water for medicine matched group, the dipyrone of intramuscular injection simultaneously.Each organizes equal administration every day 2 times, is used in conjunction 5 days, 2 days statistics curative effects after drug withdrawal.Result shows, " seven relieve internal heat clearly drink " are high, the cure rate of middle dosage group and total effective rate be respectively more than 60% and 80%, are significantly higher than low dose group, not remarkable with the difference of medicine matched group.Show that " seven relieve internal heat clearly drink " have good curative effect to pig pyretic toxicity card.
With the present invention, 5 of Shandong and Jiangsu two provinces 2582 sick pigs that pyretic toxicity card pig farm occurs have been carried out to therapeutic test, result shows that average cure rate and total effective rate are respectively 64.6% and 83.3%.
Yangzhou University's veterinary college carries out acute toxicity test, subchronic toxicity test to the present invention " seven relieve internal heat clearly drink ", result has shown that this product is both without acute toxicity, also without subchronic toxicity, by the using method of recommending and recommended dose, using this product is safe to medication animal.
the specific embodiment:
Be below embodiments of the invention, actual use of the present invention is not limited to embodiment.
Embodiment 1: Indigo Naturalis 100kg, Rhizoma Polygoni Cuspidati 80kg, Aloe 60kg, Flos Lonicerae 40kg, Radix Gentianae 75kg, Radix Platycodonis 25kg, Gypsum Fibrosum 120kg, make 500L.
Preparation process is as follows: above seven tastes, except Aloe, decoct with water twice, and 2 hours for the first time, add for the second time Aloe to decoct 1 hour, collecting decoction, filters, and filtrate is concentrated into about 450L, lets cool, and regulates pH 6.2, filter, filtrate is diluted with water to 500L, sterilizing, embedding.
Embodiment 2: Indigo Naturalis 90kg, Rhizoma Polygoni Cuspidati 90kg, Aloe 75kg, Flos Lonicerae 45kg, Radix Gentianae 60kg, Radix Platycodonis 30kg, Gypsum Fibrosum 110kg, make 500L.
Preparation process is as follows: above seven tastes, except Aloe, decoct with water twice, and 2 hours for the first time, add for the second time Aloe to decoct 1 hour, collecting decoction, filters, and filtrate is concentrated into about 450L, lets cool, and regulates pH 6.4, filter, filtrate is diluted with water to 500L, sterilizing, embedding.
Above specific embodiments of the invention be have been described in detail, but it is just as example, the present invention is not restricted to specific embodiment described above.To those skilled in the art, any equivalent modifications that the present invention is carried out and alternative also all among category of the present invention.Therefore,, not departing from the equalization conversion of doing under spirit of the present invention and category and revising, all should contain within the scope of the invention.

Claims (3)

1. medicine for animals " seven relieve internal heat clearly drink ", by weight, raw material is composed as follows: Indigo Naturalis 180~220g, Rhizoma Polygoni Cuspidati 150~180g, Aloe 100~150g, Flos Lonicerae 75~100g, Radix Gentianae 120~160g, Radix Platycodonis 30~60g, Gypsum Fibrosum 200~300g, make 1000ml.
2. " seven relieve internal heat clearly drink " as claimed in claim 1, its method for making is: above seven tastes, except Aloe, decoct with water twice, 2 hours for the first time, add for the second time Aloe to decoct 1 hour, collecting decoction, filters, and filtrate is concentrated into about 900ml, let cool, regulate pH 5.5~6.5, filter, filtrate is diluted with water to 100ml, sterilizing, embedding and get final product.
3. " seven relieve internal heat clearly drink " as described in claim 1~2, its formula optimization is: Indigo Naturalis 200g, Rhizoma Polygoni Cuspidati 160g, Aloe 120g, Flos Lonicerae 80g, Radix Gentianae 150g, Radix Platycodonis 50g, Gypsum Fibrosum 240g, make 1000ml, every 100ml " seven relieve internal heat clearly drink " is equivalent to crude drug in whole 100g.
CN201310650552.2A 2013-12-03 2013-12-03 Qiqing baidu drink and preparation method thereof Pending CN103638268A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1298714A (en) * 2000-04-26 2001-06-13 陈月秋 Medicine for treating hog cholera
CN102008556A (en) * 2009-09-08 2011-04-13 河南惠通天下动物药业有限公司 Qiqing Baidu effervescent granule and preparation method thereof
CN102362909A (en) * 2011-06-29 2012-02-29 纽素乐必佳(天津)药业集团有限公司 Method for preparing schizonepeta and divaricate saposhnikovia root oral liquid for removing toxin
CN102846726A (en) * 2012-09-06 2013-01-02 郑州后羿制药有限公司 Chinese thorowax root and baikal skullcap root extract injection for treating pig hyperpyrexia syndrome, and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1298714A (en) * 2000-04-26 2001-06-13 陈月秋 Medicine for treating hog cholera
CN102008556A (en) * 2009-09-08 2011-04-13 河南惠通天下动物药业有限公司 Qiqing Baidu effervescent granule and preparation method thereof
CN102008556B (en) * 2009-09-08 2012-06-06 河南惠通天下动物药业有限公司 Qiqing Baidu effervescent granule and preparation method thereof
CN102362909A (en) * 2011-06-29 2012-02-29 纽素乐必佳(天津)药业集团有限公司 Method for preparing schizonepeta and divaricate saposhnikovia root oral liquid for removing toxin
CN102846726A (en) * 2012-09-06 2013-01-02 郑州后羿制药有限公司 Chinese thorowax root and baikal skullcap root extract injection for treating pig hyperpyrexia syndrome, and preparation method thereof

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Application publication date: 20140319