CN103623289B

CN103623289B - The Chinese medicine preparation of a kind of hair growth and preparation method

Info

Publication number: CN103623289B
Application number: CN201310673748.3A
Authority: CN
Inventors: 王纯治
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-12-13
Filing date: 2013-12-13
Publication date: 2016-06-15
Anticipated expiration: 2033-12-13
Also published as: CN103623289A

Abstract

The Chinese medicine preparation of a kind of hair growth of disclosure and preparation method, it is characterised in that be made up of the raw material of Chinese medicine of following weight proportion: Radix Rehmanniae 40-50 part, Radix Scrophulariae 30-50 part, Radix Ophiopogonis 30-50 part, Herba Ephedrae 8-15 part, Ramulus Cinnamomi 10-15 part, Radix Pseudostellariae 50-70 part, Radix Astragali 20-40 part, Rhizoma Dioscoreae 20-40 part, Herba Houttuyniae 20-40 part, Semen Coicis 20-40 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-20 part, Cacumen Platycladi 20-40 part, Radix Polygoni Multiflori 15-30 part, Folium Perillae 10-20 part, Maifanitum 10-25 part. Having evident in efficacy, cure rate is high, and relapse rate is low, and avoids the side effect using traditional external abrasive cleaner to cause.

Description

The Chinese medicine preparation of a kind of hair growth and preparation method

Technical field:

The present invention relates to technical field of Chinese medicines, be exactly Chinese medicine preparation and the preparation method of a kind of hair growth specifically.

Background technology:

Alopecia or title alopecia, be a kind of common hair diseases. Its kind is more, such as congenital alopecia, posteriority alopecia, alopecia cicatrisata, alopecia areata and seborrheic alopecia etc. Most common of which is fat mountain pass alopecia, next to that alopecia areata. They are more common in person between twenty and fifty, due to impact beauty treatment, often bring much worried and painful to patient.

The traditional Chinese medical science thinks hair is the sign of blood condition, and therefore when the deficiency of liver-blood of people, deficiency of kidney-QI, hair becomes pale, and easy what comes off. Along with the fast development of China's economy, people are at life, work, pressure in study also in continuous increase, the continuous quickening of rhythm of life, and the rule of life causing people is also often disorderly. What this was all serious affects the healthy of people. Therefore, when human body self dysfunction, the growth conditions of hair has suffered destruction, alopecia also just it occur frequently that. According to relevant statistics, the sickness rate of China's alopecia is up to 20-24%, say, that have several hundred million people to be annoying by alopecia, and the alopecia of China morbidity crowd is while increasing year by year, and morbidity crowd also presents rejuvenation.

At present, Western medicine there is no specific treatment method for alopecia, and uses existing Chinese traditional patent formulation hair growth unsatisfactory curative effect usually occur, the course for the treatment of problem such as length.

Summary of the invention:

The deficiency that the present invention is contemplated to overcome in prior art to alopeciaing therapeutic, it is provided that a kind of have that curative effect is fast for alopeciaing therapeutic, short treating period, to control recurrence rate after healing low, and the Chinese medicine preparation having no side effect.

The present invention needs the preparation method that another problem is that described Chinese medicine preparation solved.

Technical scheme provided by the present invention is as follows:

The Chinese medicine preparation of a kind of hair growth and preparation method, it is characterised in that be made up of the raw material of Chinese medicine of following weight proportion: Radix Rehmanniae 40-50 part, Radix Scrophulariae 30-50 part, Radix Ophiopogonis 30-50 part, Herba Ephedrae 8-15 part, Ramulus Cinnamomi 10-15 part, Radix Pseudostellariae 50-70 part, Radix Astragali 20-40 part, Rhizoma Dioscoreae 20-40 part, Herba Houttuyniae 20-40 part, Semen Coicis 20-40 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-20 part, Cacumen Platycladi 20-40 part, Radix Polygoni Multiflori 15-30 part, Folium Perillae 10-20 part, Maifanitum 10-25 part.

It is preferably:

50 parts of the Radix Rehmanniae, Radix Scrophulariae 40 parts, Radix Ophiopogonis 40 parts, 12 parts of Herba Ephedrae, Ramulus Cinnamomi 12 parts, Radix Pseudostellariae 60 parts, the Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Herba Houttuyniae 30 parts, Semen Coicis 30 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 15 parts, Cacumen Platycladi 30 parts, the Radix Polygoni Multiflori 20 parts, Folium Perillae 15 parts, Maifanitum 20 parts.

The preparation method of the Chinese medicine preparation of the present invention comprises the following steps that 1, is cleaned for several times with the saline of 5% by the raw material of Chinese medicine of described weight proportion, then rinsing for several times with clear water, is finally putting in drying baker and dries; 2, the raw material of Chinese medicine mixing that will dry, is crushed to the coarse powder of 100 to 200 orders; 3, by after the described coarse powder soak with ethanol 72 hours with 65%, by carrying out the vacuum back-flow of 3 times, extracting, stand 48 hours after being filtered by gained liquid, filter and remove residue adds distilled water diluting concentration of alcohol to 7%-5% sterilizing, 150ml bottling under aseptic condition.

Raw material of Chinese medicine used in the present invention is studied and in Chinese medical discrimination for alopecia rationale for many years through inventor: " alopecia belongs to deficiency of liver-blood, deficiency of kidney-essence, stagnation of liver-QI then blood deficiency, blood deficiency is then sent out not flourish. " present invention is according to theory of Chinese medical science and herbal nature, with clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, based on nourishing YIN and benefiting blood, by regulating vim and vigour running, hair follicle stimulating regenerates, thus reaching the purpose of hair growth. Effect and the pharmacological action of each raw material of Chinese medicine used in the present invention are as follows:

The Radix Rehmanniae: sweet in the mouth, cold in nature. GUIXIN, liver, kidney channel. There is clearing away heat and cooling blood, effect of YIN nourishing and the production of body fluid promoting. Experiments show that: rat formaldehyde arthritis and albumen arthritis are had an obvious antagonism by Radix Rehmanniae decoct gavage, and granuloma that Oleum Terebinthinae subcutaneous injection causes and the increase of the capillary permeability that histamine causes can be suppressed. The mouse peritoneum inflammation that the vascular permeability that histamine is caused by Rehmannia glutinosa Libosch Water extracting solution increases and acetic acid causes has obvious inhibiting effect, and Ovum Gallus domesticus album induced Acute inflammation is also had antiinflammatory action. During Bufo siccus back leg perfusion Radix Rehmanniae extractum, intermediate concentration makes vasoconstriction, and high concentration then distends the blood vessels.

Radix Scrophulariae: sweet in the mouth, hardship, salty, cold in nature. Return lung, stomach, kidney channel. There is clearing away heat and cooling blood, effect of YIN nourishing removing toxic substances. Research shows: the various bacteria such as staphylococcus aureus, Bacillus typhi is all had inhibitory action by this product. Infusion or decoct have effect of blood pressure lowering; Alcohol extractum aqueous solution can substantially increase coronary flow.

Radix Ophiopogonis: sweet in the mouth, micro-hardship, cold nature. GUIXIN, lung, stomach warp. There is nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the effect of the relieving restlessness that clears away heart-fire. This product decoct can improve laboratory animal hypoxia-bearing capability, increases coronary flow, and myocardial ischemia has obvious protective function, and can arrhythmia and improve the effects such as myocardial contraction.

Herba Ephedrae: acrid in the mouth, micro-hardship, warm in nature. Return lung, bladder warp. There is relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, effect of inducing diuresis to remove edema. This product volatile oil has diaphoresis, refrigeration function. Ephedrine and pseudoephedrine can alleviate bronchial muscular spasm, and ephedrine has the effect of excited heart, vasoconstrictive, raising blood pressure, excited maincenter. This product also has the effect such as antiinflammatory, antibacterial, antiviral.

Ramulus Cinnamomi: its nature and flavor are pungent, sweet, enter liver,kidney,spleen, it is cure mainly the drugs for dispelling internal cold that interior cold is conventional, there is effect of complement sun, promoting blood circulation, warming the spleen and stomach, often and tonifying liver renal drug, fill blood medicine compatibility, treatment insufficiency of kidney-YANG, decline of the fire from the gate of life, cold extremities faint pulse, treat coldness and pain in the epigastrium, arthralgia due to cold lumbago with other drugs for dispelling internal cold compatibility, has the effect of significantly analgesia and anti-cancer and cancer-preventing.

Radix Pseudostellariae: sweet in the mouth, micro-hardship, property is put down. Return spleen, lung meridian. There is effect of tonifying QI to produce body fluid. This product can QI invigorating, again can YIN nourishing and the production of body fluid promoting, and the efficacy of a drug is gentle, for the product of clear benefits simply, it is adaptable to spleen lung virtual loss, deficiency of both vital energy and Yin, gas Tianjin all diseases of deficiency;Lymphocyte is had obvious stimulation.

The Radix Astragali: sweet in the mouth, slightly warm in nature. Return lung, spleen, liver, kidney channel. Having tonifying Qi and lifting yang, benefit defends consolidating superficial resistance, inducing diuresis to remove edema, effect of holder skin ulcer granulation promoting. The decoct of this product has enhancing immunity, protects the liver, improves renal function, diuresis, improves hemorheological property, promotes the effects such as hemopoietic function, defying age, anti-stress, removing toxic substances, antibacterial, antiviral, antitumor. The effects such as contained Radix Astragali saponin has expansion blood vessel, blood pressure lowering, heart tonifying, raising cardiac muscle oxygen-resistant ability, resists myocardial ischemia, antiinflammatory.

Rhizoma Dioscoreae: sweet in the mouth, property is put down. Return spleen, lung, kidney channel. Tool " book on Chinese herbal medicine is just " is recorded: Rhizoma Dioscoreae, energy spleen invigorating qi-restoratives, grows essence and reinforces the kidney, control weakness, treats five kinds of strain and seven kinds of impairment. The light property of its gas is delayed, non-may be full-time, therefore spleen reinforcing lung must main be joined, art, the kidney invigorating water must monarch Zhu, puckery foul leukorrhea must broken thus with grinding, solid spermatorrhea is held Herba cuscutae and is helped mutually. All balls consolidate pill, also should smash end for sticking with paste. Nature and flavor are weak in a word, but can firmly help and make.

Herba Houttuyniae: cold nature, bitter in the mouth. Return lung meridian, bladder, large intestine channel. Record to this product in " Japan hanako materia medica ": " simmering in phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle cylinder, deposited malignant boil is bald in vain ".

Semen Coicis: sweet in the mouth, cold in nature. Return spleen, stomach, lung meridian. There is promoting diuresis to eliminate damp pathogen, invigorating the spleen to arrest diarrhea, the effects such as heat clearing away is got rid of, eliminating impediment. For the record of this product in Compendium of Material Medica: " positive bright medicine also, can invigorating spleen and reinforcing stomach. Reinforcing the mother-organ for treating deficiency of the son-organ, therefore consumptive lung disease, lung abscess use it. The disease of muscles and bones, with Zhi Yangming for this, therefore contracture muscular contracture migratory arthralgia person uses it. Soil can win water dehumidifying, therefore have loose bowels edema with it ". The ethanol extract of this product has anticancer, antibacterial effect.

Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae): bitter in the mouth, warm in nature. Enter lung, kidney,liver,spleen four warp. There is relaxing muscles and tendons and activating QI and blood in the collateral, circulation of qi promoting damp eliminating, the effects such as cold expelling dispels the wind, eliminating dampness to stop diarrhea.

Cacumen Platycladi: bitter in the mouth, puckery, cold nature. Return lung, liver, large intestine channel. Record to this product in tool " medical center bun want ": " let out lung inverse, eliminating heart-fire, suppressing the hyperactive liver heat, the heat purified the blood point ". Cacumen Platycladi decoct can substantially shorten bleeding time and clotting time, and its hemostasis effective ingredient is Quercetin and tannin. Additionally, still have antitussive, eliminate the phlegm, relieving asthma, the effect such as calm. Experiment in vitro shows, staphylococcus aureus, micrococcus catarrhalis, dysentery bacterium, Bacillus typhi, diphtheria corynebacterium etc. are all had inhibitory action by these product.

The Radix Polygoni Multiflori: bitter in the mouth, sweet, puckery, slightly warm in nature. Return liver, kidney channel. There is nourishing the blood and yin, crow beard and hair, strengthening bone and muscle, effect of controlling nocturnal emission with astringent drugs gas. This product, rich in lecithin, has promotion hemocyte newborn and grows, increasing the effect of liver glycogen. Also there is the effects such as enhancing immunity, defying age, increase coronary flow, antibacterial, antiviral.

Folium Perillae: acrid in the mouth, slightly warm in nature. Return spleen, lung meridian. There is the effects such as relieving the exterior syndrome by diaphoresis, promoting the circulation of QI to alleviate the stagnation in middle-JIAO. The water decoction of this product and alcohol immersion all have skin expansion blood vessel, stimulate the effect of sweat gland secretion, in addition also have the secretion of facilitating digestion liquid, increase the effects such as gastrointestinal peristalsis.

Maifanitum: harmful several units such as cadmium, hydrargyrum, arsenic, lead are have stronger absorbability. Test result indicate that, mice is had resisting fatigue, oxygen lack resistant function by Maifanitum.

It is an advantage of the current invention that: adopt natural Chinese medicines to make, with clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, based on nourishing YIN and benefiting blood, by regulating vim and vigour running, hair follicle stimulating regenerates, thus reaching the purpose of hair growth, having evident in efficacy, cure rate is high, relapse rate is low, and avoids the side effect using traditional external abrasive cleaner to cause.

Detailed description of the invention:

Embodiment 1:

The optimization formula of the present invention: 50 parts of the Radix Rehmanniae, Radix Scrophulariae 40 parts, Radix Ophiopogonis 40 parts, 12 parts of Herba Ephedrae, Ramulus Cinnamomi 12 parts, Radix Pseudostellariae 60 parts, the Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Herba Houttuyniae 30 parts, Semen Coicis 30 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 15 parts, Cacumen Platycladi 30 parts, the Radix Polygoni Multiflori 20 parts, Folium Perillae 15 parts, Maifanitum 20 parts.

Preparation method:

Prepared by the Chinese medicine preparation of the present invention specifically comprises the following steps that 1, is cleaned for several times with the saline of 5% by the raw material of Chinese medicine of described weight proportion, then rinsing for several times with clear water, is finally putting in drying baker and dries; 2, the raw material of Chinese medicine mixing that will dry, is crushed to the coarse powder of 100 to 200 orders; 3, by after the described coarse powder soak with ethanol 72 hours with 65%, by carrying out the vacuum back-flow of 3 times, extracting, stand 48 hours after being filtered by gained liquid, filter and remove residue adds distilled water diluting concentration of alcohol to 7%-5% sterilizing, and aseptic 150ml bottles.

Embodiment 2:

The using method of the present invention: morning, noon and afternoon every day after meal, take 50ml, one week is a course for the treatment of.

Inventor uses the Chinese medicine preparation of the present invention that 103 patients have been treated for many years, wherein male 64 example, and women 39 example, 36 years old patient's mean age, alopecia areata, alopecia universalis, alopecia totalis account for 43 examples, and seborrheic alopecia accounts for 60 examples. After using the present invention to treat 4 courses for the treatment of, 43 examples of fully recovering, account for the 41.74% of total number of persons, take a turn for the better 53 examples, accounts for the 51.45% of total number of persons, and invalid 7 examples account for the 6.54% of total number of persons.

Criterion of therapeutical effect is as follows:

Recovery from illness: hair stops coming off, new regeneration rate of sending out reaches more than 75%, and head sebum secretion substantially reduces.

Taking a turn for the better: alopecia situation has bright improvement, new regeneration rate of sending out reaches more than 15%.

Invalid: to be clearly distinguished from nothing before treatment.

Model case:

1, Zhang, female, 45 years old, within 04 year, play unknown cause and start alopecia, there is no any improvement through multi-treatment, the Chinese medicine preparation starting to take the present invention for 09 year, after treating 2 courses for the treatment of, depilation phenomenon stops, and the top of the head has trickle fine hair to grow, have continuation medication treatment after 1 month hair and ordinary person be as good as, do not recur so far.

2, Lee, man, within 38 years old, suffer from alopecia areata for many years, any improvement is not had through multi-treatment, after within 10 years, starting to take 4 courses for the treatment of of Chinese medicine preparation treatment of the present invention, effect is notable, continues again recovery from illness after medication treatment one and a half months, and drug withdrawal does not have the phenomenon that hair comes off again to occur over 2 years.

Claims

1. the oral preparation of Chinese traditional medicinal of a hair growth, it is characterised in that be made up of the raw material of Chinese medicine of following weight proportion: Radix Rehmanniae 40-50 part, Radix Scrophulariae 30-50 part, Radix Ophiopogonis 30-50 part, Herba Ephedrae 8-15 part, Ramulus Cinnamomi 10-15 part, Radix Pseudostellariae 50-70 part, Radix Astragali 20-40 part, Rhizoma Dioscoreae 20-40 part, Herba Houttuyniae 20-40 part, Semen Coicis 20-40 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-20 part, Cacumen Platycladi 20-40 part, Radix Polygoni Multiflori 15-30 part, Folium Perillae 10-20 part, Maifanitum 10-25 part.

2. the oral preparation of Chinese traditional medicinal of a kind of hair growth according to claim 1, it is characterised in that be made up of the raw material of Chinese medicine of following weight proportion: 50 parts of the Radix Rehmanniae, Radix Scrophulariae 40 parts, Radix Ophiopogonis 40 parts, 12 parts of Herba Ephedrae, Ramulus Cinnamomi 12 parts, Radix Pseudostellariae 60 parts, the Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Herba Houttuyniae 30 parts, Semen Coicis 30 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 15 parts, Cacumen Platycladi 30 parts, the Radix Polygoni Multiflori 20 parts, Folium Perillae 15 parts, Maifanitum 20 parts.

3. the preparation method of the oral preparation of Chinese traditional medicinal of a kind of hair growth according to claim 1 or 2, it is characterized in that: the preparation method of described Chinese medicine preparation specifically comprises the following steps that 1, cleaned for several times with the saline of 5% by the raw material of Chinese medicine of described weight proportion, then rinse for several times with clear water again, be finally putting in drying baker and dry;2, the raw material of Chinese medicine mixing that will dry, is crushed to the coarse powder of 100 to 200 orders; 3, by after the described coarse powder soak with ethanol 72 hours with 65%, by carrying out the vacuum back-flow of 3 times, extracting, stand 48 hours after being filtered by gained liquid, filter and remove residue adds distilled water diluting concentration of alcohol to 5%-7% sterilizing, 150ml bottling under aseptic condition.