CN103610903A - Plaster for treating type II diabetes mellitus - Google Patents
Plaster for treating type II diabetes mellitus Download PDFInfo
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- CN103610903A CN103610903A CN201310572954.5A CN201310572954A CN103610903A CN 103610903 A CN103610903 A CN 103610903A CN 201310572954 A CN201310572954 A CN 201310572954A CN 103610903 A CN103610903 A CN 103610903A
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- ointment
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Abstract
The invention discloses a plaster for treating type II diabetes mellitus and relates to a plaster. The plaster comprises the following raw medicines weight: 1560-1750 grams of hot melt adhesive, 135-155 grams of raw astragalus, 50-80 grams of pilose asiabell root, 70-95 grams of herba epimedii, 135-155 grams of paenoiae alba, 50-80 grams of raw liquorice, 65-85 grams of dark plum, 60-75 grams of Chinese yam, 61-76 grams of dwarf lilyturf root, 62-78 grams of kudzu vine root and 10-20ml of azone. The plaster for treating the type II diabetes mellitus has the characteristics of accuratemedicine use and high active ingredient content and has strong penetration capacity and capacity of permeating into subcutaneous tissue; particularly when the plaster is applied to the Shenque acupoint, the functions of tonifying kidney and benefiting qi, saving effort and retaining yin, nourishing spleen and quenching thirst are realized through absorption; the plaster has remarkable curative effect on the type II diabetes mellitus.
Description
Technical field
The present invention relates to a kind of plaster, be specifically related to a kind of plaster that is used for the treatment of type Ⅱdiabetes mellitus.
Background technology
At present, in clinical, for type Ⅱdiabetes mellitus, conventionally adopt oral drugs, intramuscular injection or transfusion are treated, and oral medicine stimulates larger to gastrointestinal, patient's endurable, and intramuscular injection, transfusion can produce damage in various degree to liver, kidney.The more existing drug use effect that is used for the treatment of diabetes is also not ideal enough, and its main cause is: raw material is chosen accurate not, and patient's Long-term taking medicine is difficult to adhere to, the active constituent content of plaster is low, and the permeability of plaster is not good.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of materials accurate, and active constituent content is high, the plaster that is used for the treatment of type Ⅱdiabetes mellitus of good penetrability.
Technical problem to be solved by this invention realizes by the following technical solutions:
A plaster that is used for the treatment of type Ⅱdiabetes mellitus, is comprised of the crude drug of following weight:
Thermosol 1560-1750 gram, Radix Astragali 135-155 gram, Radix Codonopsis 50-80 gram, Herba Epimedii 70-95 gram, Radix Paeoniae Alba 135-155 gram, Radix Glycyrrhizae 50-80 gram, Fructus Mume 65-85 gram, Rhizoma Dioscoreae 60-75 gram, 61-76 gram of Radix Ophiopogonis, Radix Puerariae 62-78 gram, azone 10-20 milliliter.
Another object of the present invention is to provide a kind of method of preparing plaster of the present invention: the substrate using the PUR of making for plaster as ointment, the Radix Astragali, Radix Codonopsis, Herba Epimedii, Radix Paeoniae Alba, Radix Glycyrrhizae, Fructus Mume, Rhizoma Dioscoreae, Radix Ophiopogonis, Radix Puerariae were soaked in water to 20-30 as a child, water decocts 2-3 time, each extracting juice that decocts removes slag, then concentrated after the medicine juice obtaining being merged, obtain spice extractum; By ointment substrate heating and melting, then add spice extractum, azone to be fully uniformly mixed, obtain ointment; Get it filled in cream beach framed back material, after ointment is cooled to solid, both obtained plaster.
In formula, one to be selected targetedly have the pigment medicine of significant curative effect to diabetes in the present invention, and the 2nd, select azone, azone is a kind of absorbent of transdermal, is added in pharmaceutical formulation, and the effect of Transdermal absorption can be provided.
In the preparation method of plaster that is used for the treatment of type Ⅱdiabetes mellitus provided by the invention, by spice water boiling and extraction, can guarantee the content of effective ingredient in plaster, and traditional by the way of spice " oil plant is endured withered ", many effective ingredient that can Liaozhong destroy.
The invention has the beneficial effects as follows: it is accurate that the plaster that is used for the treatment of type Ⅱdiabetes mellitus provided by the invention has medication, active constituent content is high, there is stronger infiltration and infiltrate hypodermic ability, particularly be attached to SHENQUE acupoint, through absorption, reach and tonify Qi of the kidney, yin fluid astringing saves labour, grow the effect that spleen quenches the thirst, it has significant curative effect to type Ⅱdiabetes mellitus.
The specific embodiment
For technological means, creation characteristic that the present invention is realized, reach object and effect is easy to understand, below in conjunction with specific embodiment, further set forth the present invention.
Embodiment 1
A plaster that is used for the treatment of type Ⅱdiabetes mellitus, takes 1600 grams of PURs, 140 grams of Radix Astragali, 70 grams of Radix Codonopsis, 90 grams of Herba Epimedii, 140 grams of Radix Paeoniae Alba, 75 grams of Radix Glycyrrhizae, 75 grams of Fructus Mumes, 70 grams of Rhizoma Dioscoreaes, 70 grams of Radix Ophiopogonis, 72 grams of Radix Puerariaes, 15 milliliters of azones.
Take the PUR made for plaster as the substrate of ointment, the Radix Astragali, Radix Codonopsis, Herba Epimedii, Radix Paeoniae Alba, Radix Glycyrrhizae, Fructus Mume, Rhizoma Dioscoreae, Radix Ophiopogonis, Radix Puerariae were soaked in water to 20-30 as a child, water decocts 2-3 time, amount of water is good higher than spice 2-3cm, decocts at every turn to expenses for medicine boiling, then decocts 40-50 minute with little fire, each extracting juice that decocts removes slag, then concentrated after the medicine juice obtaining being merged, then go sticky medicine juice to become to hang flag shape with Glass rod, obtain spice extractum; By ointment substrate heating and melting, be cooled to 65-70 ℃, then add spice extractum, azone to be fully uniformly mixed, obtain ointment; Get it filled in cream 9-10 gram of beach framed back material, in framed back material, adopt desensitization medical non-woven adhesive plaster, after ointment is cooled to solid, had both obtained one and forced on, by sealing in the multiple aluminium plastic bag of the plaster dress making and leave in the container of sealing, be placed in dry, the keeping of shady and cool place.
This plaster is in use: ointment, with after little baking, is affixed on to SHENQUE acupoint, within every two days, changes once, within 30 days, be a course for the treatment of.
Embodiment 2
A plaster that is used for the treatment of type Ⅱdiabetes mellitus, takes 1750 grams of thermosols, 155 grams of Radix Astragali, 80 grams of Radix Codonopsis, 95 grams of Herba Epimedii, 155 grams of Radix Paeoniae Alba, 80 grams of Radix Glycyrrhizae, 85 grams of Fructus Mumes, 75 grams of Rhizoma Dioscoreaes, 76 grams of Radix Ophiopogonis, 78 grams of Radix Puerariaes, 20 milliliters of azones.
Take the PUR made for plaster as the substrate of ointment, the Radix Astragali, Radix Codonopsis, Herba Epimedii, Radix Paeoniae Alba, Radix Glycyrrhizae, Fructus Mume, Rhizoma Dioscoreae, Radix Ophiopogonis, Radix Puerariae were soaked in water to 20-30 as a child, water decocts 2-3 time, amount of water is good higher than spice 2-3cm, decocts at every turn to expenses for medicine boiling, then decocts 40-50 minute with little fire, each extracting juice that decocts removes slag, then concentrated after the medicine juice obtaining being merged, then go sticky medicine juice to become to hang flag shape with Glass rod, obtain spice extractum; By ointment substrate heating and melting, be cooled to 65-70 ℃, then add spice extractum, azone to be fully uniformly mixed, obtain ointment; Get it filled in cream 9-10 gram of beach framed back material, in framed back material, adopt desensitization medical non-woven adhesive plaster, after ointment is cooled to solid, had both obtained one and forced on, by sealing in the multiple aluminium plastic bag of the plaster dress making and leave in the container of sealing, be placed in dry, the keeping of shady and cool place.
This plaster is in use: ointment, with after little baking, is affixed on to SHENQUE acupoint, within every two days, changes once, within 30 days, be a course for the treatment of.
For better checking curative effect of the present invention, below by the contrast experiment of curative effect group, matched group, further illustrate the beneficial effect of plaster provided by the invention to type Ⅱdiabetes mellitus.
1, grouping and Therapeutic Method
1.1, grouping, is successively divided into treatment group and matched group by patient, treatment group 54 examples, matched group 51 examples at random by consultation time.
1.2, treatment group, is used plaster provided by the invention to treat patients with NIDDM.
1.3, matched group, the JINQI JIANGTANG PIAN of using commercially available Tianjin Traditional Chinese Medicine Factory to produce is treated patients with NIDDM.
1.4, the course for the treatment of, treatment group and matched group are a course for the treatment of in equal 30 days.
2, the related data for the treatment of group and matched group.
2.1, Sex distribution is in Table one:
Table one
| Group | Number of cases | Man | Female |
| Treatment group | 54 | 38 | 16 |
| Matched group | 51 | 30 | 21 |
2.2, age distribution is in Table two
Table two
| Group | Number of cases | Below 40 years old | 41-60 year | More than 60 years old |
| Treatment group | 54 | 6 | 32 | 16 |
| Matched group | 51 | 5 | 26 | 20 |
2.3, course of disease situation is in Table three
Table three
| Group | Number of cases | Below 2 years | 3-5 | 6-10 | More than 10 years |
| Treatment group | 54 | 3 | 32 | 11 | 8 |
| Matched group | 51 | 4 | 26 | 12 | 9 |
2.4, medicine typing, in Table four
Table four
3, efficacy assessment standard
3.1, cure, transference cure, lab testing is repeatedly normal.
3.2, take a turn for the better, cardinal symptom and relevant lab testing are improved.
3.3, do not heal, symptom and lab testing are unchanged.
4, experimental result (after 3 courses for the treatment of) is in Table 5
Table five
| Group | Number of cases | Cure | Take a turn for the better | Do not heal | Total effective rate % |
| Treatment group | 54 | 10 | 39 | 5 | 90.7% |
| Matched group | 51 | 7 | 35 | 9 | 82.4% |
By above experiment, can be found out, plaster provided by the invention has more significant curative effect for treatment type Ⅱdiabetes mellitus.
More than show and described ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; that in above-described embodiment and description, describes just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.The claimed scope of the present invention is defined by appending claims and equivalent thereof.
Claims (3)
1. the plaster that is used for the treatment of type Ⅱdiabetes mellitus, is characterized in that: this plaster is comprised of the crude drug of following weight,
Thermosol 1560-1750 gram, Radix Astragali 135-155 gram, Radix Codonopsis 50-80 gram, Herba Epimedii 70-95 gram, Radix Paeoniae Alba 135-155 gram, Radix Glycyrrhizae 50-80 gram, Fructus Mume 65-85 gram, Rhizoma Dioscoreae 60-75 gram, 61-76 gram of Radix Ophiopogonis, Radix Puerariae 62-78 gram, azone 10-20 milliliter.
2. the plaster that is used for the treatment of type Ⅱdiabetes mellitus according to claim 1, is characterized in that: preferred plaster is comprised of the crude drug of following weight:
1600 grams of PURs, 140 grams of Radix Astragali, 70 grams of Radix Codonopsis, 90 grams of Herba Epimedii, 140 grams of Radix Paeoniae Alba, 75 grams of Radix Glycyrrhizae, 75 grams of Fructus Mumes, 70 grams of Rhizoma Dioscoreaes, 70 grams of Radix Ophiopogonis, 72 grams of Radix Puerariaes, 15 milliliters of azones.
3. the preparation method of plaster that is used for the treatment of type Ⅱdiabetes mellitus according to claim 1, it is characterized in that: the substrate using the PUR of making for plaster as ointment, the Radix Astragali, Radix Codonopsis, Herba Epimedii, Radix Paeoniae Alba, Radix Glycyrrhizae, Fructus Mume, Rhizoma Dioscoreae, Radix Ophiopogonis, Radix Puerariae were soaked in water to 20-30 as a child, water decocts 2-3 time, each extracting juice that decocts removes slag, then concentrated after the medicine juice obtaining being merged, obtain spice extractum; By ointment substrate heating and melting, then add spice extractum, azone to be fully uniformly mixed, obtain ointment; Get it filled in cream beach framed back material, after ointment is cooled to solid, both obtained plaster.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310572954.5A CN103610903A (en) | 2013-11-13 | 2013-11-13 | Plaster for treating type II diabetes mellitus |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310572954.5A CN103610903A (en) | 2013-11-13 | 2013-11-13 | Plaster for treating type II diabetes mellitus |
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| CN103610903A true CN103610903A (en) | 2014-03-05 |
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| CN201310572954.5A Pending CN103610903A (en) | 2013-11-13 | 2013-11-13 | Plaster for treating type II diabetes mellitus |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306873A (en) * | 2014-09-23 | 2015-01-28 | 黄厚生 | Traditional Chinese medicine preparation for treating neck shoulder syndromes and preparing method thereof |
| CN104367833A (en) * | 2014-11-08 | 2015-02-25 | 欧阳永辉 | Traditional Chinese medicine for treating diabetes mellitus |
| CN105250981A (en) * | 2015-11-22 | 2016-01-20 | 青岛麦瑞特医药技术有限公司 | Traditional Chinese medicine composition for treating diabetic foot |
| CN108553533A (en) * | 2018-04-13 | 2018-09-21 | 石如全 | A kind of plaster and preparation method thereof for treating diabetes |
| CN109568496B (en) * | 2019-01-10 | 2021-03-30 | 陈浩 | Detection method of traditional Chinese medicine composition for treating diabetes |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101120971A (en) * | 2006-08-08 | 2008-02-13 | 芮育健 | New use of traditional Chinese medicines radix astragali, white peony root and purearia root for kidney-tonifying qi-replenishing and treating diabetes |
-
2013
- 2013-11-13 CN CN201310572954.5A patent/CN103610903A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101120971A (en) * | 2006-08-08 | 2008-02-13 | 芮育健 | New use of traditional Chinese medicines radix astragali, white peony root and purearia root for kidney-tonifying qi-replenishing and treating diabetes |
Non-Patent Citations (1)
| Title |
|---|
| 邱天道等: "三消降糖膏治疗II型糖尿病82例", 《中医外治杂志》, vol. 7, no. 4, 31 August 1998 (1998-08-31) * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306873A (en) * | 2014-09-23 | 2015-01-28 | 黄厚生 | Traditional Chinese medicine preparation for treating neck shoulder syndromes and preparing method thereof |
| CN104367833A (en) * | 2014-11-08 | 2015-02-25 | 欧阳永辉 | Traditional Chinese medicine for treating diabetes mellitus |
| CN105250981A (en) * | 2015-11-22 | 2016-01-20 | 青岛麦瑞特医药技术有限公司 | Traditional Chinese medicine composition for treating diabetic foot |
| CN108553533A (en) * | 2018-04-13 | 2018-09-21 | 石如全 | A kind of plaster and preparation method thereof for treating diabetes |
| CN109568496B (en) * | 2019-01-10 | 2021-03-30 | 陈浩 | Detection method of traditional Chinese medicine composition for treating diabetes |
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Application publication date: 20140305 |