CN103610779A - Traditional Chinese medicine preparation for treating threatened abortion - Google Patents

Traditional Chinese medicine preparation for treating threatened abortion Download PDF

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CN103610779A
CN103610779A CN201310669810.1A CN201310669810A CN103610779A CN 103610779 A CN103610779 A CN 103610779A CN 201310669810 A CN201310669810 A CN 201310669810A CN 103610779 A CN103610779 A CN 103610779A
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chinese medicine
medicine preparation
treatment
traditional chinese
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卢潭敏
李玉珍
周海燕
肖岩
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating threatened abortion. The traditional Chinese medicine preparation is prepared from the following raw material medicines: 10-15 g of loranthus parasiticus, 10-20 g of semen cuscutae, 10-15 g of dipsacus asper, 10-20 g of colla corii asini, 10-15 g of astragalus membranaceus, 10-15 g of fried rhizoma atractylodis, 4-9 g of radix scutellariae, 10-20 g of eucommia ulmoides and 8-12 g of red dates. Preparation and treatment methods comprise the following steps: placing the various raw material medicines in a marmite, adding water of which the amount is 5-8 times that of the various raw material medicines so as to immerse the various raw material medicines, soaking the various raw material medicines for 1-1.5 hours, decocting the various raw material medicines for 1 hour, and filtering to obtain the traditional Chinese medicine preparation, and taking the traditional Chinese medicine preparation after warming, wherein one treatment course lasts 30 days. In the preparation, the astragalus membranaceus, the fried rhizoma atractylodis, the red dates and the like are capable of invigorating the spleen, supplementing qi and nourishing blood, the loranthus parasiticus, the semen cuscutae and the like are capable of tonifying the kidney and calming fetus, the colla corii asini is capable of enriching blood, and due to the compatibility of the various medicines, the traditional Chinese medicine preparation has the effects of clearing heat and nourishing blood, and nourishing the kidney and calming fetus. The preparation is capable of tonifying qi and harmonizing blood, and activating blood and calming fetus, remarkable in effect, and low in treatment cost during treatment on threatened abortion.

Description

A kind of Chinese medicine preparation for the treatment of threatened abortion
 
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of threatened abortion.
Background technology
Threatened abortion refers to before pregnant 28 weeks, first occurs a small amount of colporrhagia, then occurs paroxysmal lower abdominal pain or lumbago, and pelvioscopy palace mouth is not opened, and intact fetal membranes is discharged without pregnant thing, uterus size and pregnant Zhou Xiangfu.As symptom increases the weight of, may develop into inevitable abortion.The cause of disease common are: 1. chromosomal abnormality: chromosomal abnormality is the main cause of miscarriage.In spontaneous abortion, there is in early days 50%~60% pregnant thing to have chromosomal abnormality.Abnormal if any a human chromosome in Mr. and Mrs, it can reach filial generation, can cause miscarriage or habitual abortion.2. maternal factors, as merged undesirable element in chronic disease, cryptorrhea, immunologic dysfunction, serious malnutrition, smoking, excessive drinking bad habit, environment, uterus defect, wound, emotional problems etc.Common clinical manifestation is: 1. menolipsis: most of spontaneous abortion all has obvious menolipsis history.2. vaginal hemorrhage and stomachache: the symptom first occurring is vaginal hemorrhage often, general amount of bleeding is few, is often kermesinus, or is sanguinous leukorrhea, but last, sometimes can reach 4~5 days to more than one week.After the appearance of bleeding, a few hours, can be with slight lower abdominal pain or lumbago and backache to several weeks, and after pregnant 12 weeks, patient can feel paroxysmal abdominal pain sometimes.Gestation terminator before 28 weeks is called miscarriage.As natural termination person before pregnant 12 weeks claims early abortion, in gestation, 13~27 weeks natural termination persons are late abortion.From different regions, the statistics of different estate and all ages and classes, the incidence rate of spontaneous abortion is 15%~40%, approximately 75% occur in pregnant 16 weeks before, the former accounts for 62% to betide gestation 12 weeks.
Different for the Western medicine kind of threatened abortion in the market, but because Western medicine side effect is larger, anemia of pregnant woman is many dare not take, and that the performance of Chinese medicine warm and conditioning is applied is herein comparatively suitable.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of Chinese medicine preparation for the treatment of threatened abortion, its treatment cost is low, and therapeutic effect is good.
The present invention is achieved by the following technical solutions:
Treat a Chinese medicine preparation for threatened abortion, by following crude drug, made: 10 ~ 15 grams of Herba Taxillis, 10 ~ 20 grams of Semen Cuscutae, 10 ~ 15 grams of Radix Dipsaci, 10 ~ 20 grams, Colla Corii Asini, 10 ~ 15 grams of the Radixs Astragali, 10 ~ 15 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 4 ~ 9 grams of Radix Scutellariae, 10 ~ 20 grams of the Cortexs Eucommiae, 8 ~ 12 grams of Fructus Jujubaes.
Preferably, by following crude drug, made: 12 grams of Herba Taxillis, 15 grams of Semen Cuscutae, 12 grams of Radix Dipsaci, 15 grams, Colla Corii Asini, 12 grams of the Radixs Astragali, 12 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 6 grams of Radix Scutellariae, 15 grams of the Cortexs Eucommiae, 10 grams of Fructus Jujubaes.
Preferably, by following crude drug, made: 10 grams of Herba Taxillis, 10 grams of Semen Cuscutae, 10 grams of Radix Dipsaci, 10 grams, Colla Corii Asini, 10 grams of the Radixs Astragali, 10 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 4 grams of Radix Scutellariae, 10 grams of the Cortexs Eucommiae, 8 grams of Fructus Jujubaes.
Preferably, by following crude drug, made: 15 grams of Herba Taxillis, 20 grams of Semen Cuscutae, 15 grams of Radix Dipsaci, 20 grams, Colla Corii Asini, 15 grams of the Radixs Astragali, 15 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 9 grams of Radix Scutellariae, 20 grams of the Cortexs Eucommiae, 12 grams of Fructus Jujubaes.
The preparation method of the Chinese medicine preparation of described treatment threatened abortion, step is: get each crude drug and be put in marmite, add 5 ~ 8 times of water loggings not have, soak 1 ~ 1.5 hour, decoct 1 hour, filter, obtain.
Chinese medicine preparation of the present invention cures mainly threatened abortion, during treatment, oral, and every dose (the above-mentioned preferred formula ratio providing is the amount of potion), every day, potion, 30 days was a course for the treatment of.General the lighter can cure a course for the treatment of, and severe one can be cured 2 ~ 3 courses for the treatment of.If genus habitual abortion, preferably is just started to take medicine by miscarriage for first 1 month, surpass and to stop using afterwards miscarriage month four, 50 days, effect is more satisfactory.
In the formula of Chinese medicine preparation of the present invention, the pharmacological action of each crude drug is as follows:
Herba Taxilli: nature and flavor are bitter, sweet, property is flat.Enter liver, kidney channel.There is invigorating the liver and kidney; Bone and muscle strengthening; Wind-damp dispelling; Antiabortive effect.Main soreness of waist and knee joint; A little less than muscles and bones flaccidity; Limbs are hemiplegia; Rheumatic arthralgia; Head is wrong dizzy; Frequent fetal movement, metrostaxis.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and metrorrhagia warp is many, blood leaking in gestation, frequent fetal movement.
Semen Cuscutae: abnormal smells from the patient is pungent, sweet, flat, nontoxic.The kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.The waist knee joint muscles and bones that is applicable to deficiency of the liver and kindey is ached, the diseases such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.
Radix Dipsaci: bitter in the mouth, pungent, slightly warm in nature.Return liver; Kidney channel.There is invigorating the liver and kidney; Bone and muscle strengthening; Blood circulation regulating; Continuous injured; Stop the effect of metrorrhagia.For aching pain in waist and back; Podomere flaccidity syndrome and arthralgia syndrome; Fall flutter wound, damage muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer are swollen.Prepared RADIX DIPSACI with yellow rice wine is used for rheumatic arthralgia, injury from falling down.
Colla Corii Asini: the YIN nourishing of enriching blood, moisturize hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.
The Radix Astragali: nature and flavor are sweet, tepor.Gui Jing: return lung, spleen, liver, kidney channel.The effect that has consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, regulating fluid apssage, the treatment deficiency of vital energy.
Rhizoma Atractylodis Macrocephalae (parched): have invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Scutellariae: have antiinflammatory, anti-allergy action; Hepatic cholagogic effect; The effect of blood pressure lowering, diuresis, calmness, refrigeration function.The clinical infectious hepatitis that is mainly used in, acute biliary infection, lead poisoning, heat-clearing and toxic substances removing, vomiting and nausea uncomfortable in chest, cough due to lung-heat, tumor sore, frequent fetal movement.
The Cortex Eucommiae: nature and flavor are sweet, micro-pungent, temperature.There is invigorating the liver and kidney, strong waist knee joint, bone and muscle strengthening, antiabortive effect.The Cortex Eucommiae has regulating action in various degree to immune system, hormonal system, central nervous system, blood circulation and urinary system, the excited Pituitary Adrenal cortex system of Cortex Eucommiae energy, adrenal cortex reinforcing function.
Fructus Jujubae: sweet in the mouth, warm in nature, taste warp, has invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, the function of the mitigation property of medicine.Modern pharmacological research is existing, and Fructus Jujubae can make oxygen content in blood strengthen, nourish systemic cell, is the analeptic that a kind of drug effect relaxes.
Threatened abortion, the traditional Chinese medical science is referred to as abdominal pain during pregnancy, vaginal bleeding during pregnancy hematochezia.If absence of vagina is hemorrhage, and only there is the swollen pendant pain person of waist abdomen acid, be called " frequent fetal movement ".The traditional Chinese medical science thinks, the formation reason of primary disease mostly is the debility of CHONG and REN meridians, due to failure of blood to nourish the fetus.Because of CHONG meridian being the blood pool, REN meridian connecting with the uterus and pregnancy, the gas-solid that punching is appointed tire has containedly, and blood is foster to some extent, and tire is pregnant can grow by normal growth; Otherwise, there is the cards such as vaginal bleeding during pregnancy, frequent fetal movement.The introduction of heat in blood: main symptom: pregnant rear vagina is hemorrhage on a small quantity, and color is scarlet or dark red, and matter is thick, the soreness of waist, stomachache, flushed complexion is vexed, dry mouth and throat, or five dysphoria with smothery sensation, constipation, yellowish urine, red tongue or limit point are red, yellow fur or few tongue, stringy and rolling pulse number.Method for the treatment of: heat clearing away is nourished blood, nourishing kidney is antiabortive.Blood stasis main symptom: have the speckle obstinate diseases such as pelvic lump or hysteromyoma, or pregnant rear wound tumbling down, vagina is hemorrhage on a small quantity, and color is dim red, lower abdomen contracture pain, soreness of waist tenesmus, tongue is dim red, and tongue is white, stringy and rolling pulse.Method for the treatment of: QI invigorating and blood regulating, invigorate blood circulation antiabortive.Therefore this disease of Chinese traditional treatment gives the kidney invigorating method of preventing miscarriage more.
In this preparation, the spleen benefiting and replenishing qi and bloods such as the Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Fructus Jujubae, the tonifying kidney for preventing miscarriage such as Herba Taxilli, Semen Cuscutae, Colla Corii Asini nourishing blood, all medicine compatibilities, have heat clearing away to nourish blood, the effect that nourishing kidney is antiabortive.Said preparation treatment threatened abortion can QI invigorating and blood regulating, invigorates blood circulation antiabortive, and effect is remarkable and treatment cost is low.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated.
1 one kinds of Chinese medicine preparation for the treatment of threatened abortion of embodiment
Formula is: 12 grams of Herba Taxillis, 15 grams of Semen Cuscutae, 12 grams of Radix Dipsaci, 15 grams, Colla Corii Asini, 12 grams of the Radixs Astragali, 12 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 6 grams of Radix Scutellariae, 15 grams of the Cortexs Eucommiae, 10 grams of Fructus Jujubaes.
Preparation method is: get each crude drug in above-mentioned formula, add 5 times of water loggings and do not have, soak 1 hour, decoct 1 hour, filter, obtain.
Usage and dosage: wait decoction being taken warmly use, every day potion, one after each meal.
2 one kinds of Chinese medicine preparation for the treatment of threatened abortion of embodiment
Formula is: 10 grams of Herba Taxillis, 10 grams of Semen Cuscutae, 10 grams of Radix Dipsaci, 10 grams, Colla Corii Asini, 10 grams of the Radixs Astragali, 10 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 4 grams of Radix Scutellariae, 10 grams of the Cortexs Eucommiae, 8 grams of Fructus Jujubaes.
Preparation method is: get each crude drug in above-mentioned formula, add 6 times of water loggings and do not have, soak 1 hour, decoct 1 hour, filter, obtain.
Usage and dosage: wait decoction being taken warmly use, every day potion, one after each meal.
3 one kinds of Chinese medicine preparation for the treatment of threatened abortion of embodiment
Formula is: 15 grams of Herba Taxillis, 20 grams of Semen Cuscutae, 15 grams of Radix Dipsaci, 20 grams, Colla Corii Asini, 15 grams of the Radixs Astragali, 15 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 9 grams of Radix Scutellariae, 20 grams of the Cortexs Eucommiae, 12 grams of Fructus Jujubaes.
Preparation method is: get each crude drug in above-mentioned formula, add 8 times of water loggings and do not have, soak 1.5 hours, decoct 1 hour, filter, obtain.
Usage and dosage: wait decoction being taken warmly use, every day potion, one after each meal.
Clinical observation:
(1) clinical data
The present invention from 2000 so far, carries out clinical treatment observation to 65 routine threatened abortion patients.
(2) Therapeutic Method
Adopt dose and the decocting method of embodiment 1 in patent of the present invention, 1 dose of every day, one after each meal, general patient takes 1 month, and what the state of an illness was heavier takes 3 months.
(3) curative effect determinate standard
Cure: symptom all disappears, without discomforts such as stomachache, lumbago, abdominal part bearing down and colporrhagias.
Effective: cardinal symptom disappears, and the state of an illness is basicly stable, random thoughts are suffered from abdominal pain or are occasionally had a small amount of colporrhagia, but can continue gestation.
Invalid: symptom before increases the weight of, or prevent miscarriage unsuccessfully.
(4) clinical effectiveness
According to above application statistics: patient took after the course for the treatment of, clinical cure 53 examples (81.5%), effective 10 examples (15.4%), invalid 2 examples (3.1%), total effective rate is 96.9%.
Way of the present invention is simple, cheap, evident in efficacy, has no side effect, safe, is conducive to the treatment of preventing miscarriage of threatened abortion.
Concrete case is as follows:
Case 1: Lee, 26 years old, Shandong Yanggu people.Head examines: on June 12nd, 2011, conceived 46 days, artificial abortion in once conceived 48 days in 2010 1 time.This has a small amount of colporrhagia, without obviously suffering from abdominal pain and other malaise symptoms.Give above Chinese medicine preparation, the decocting method of Chinese medicine decoction serve on January routinely, colporrhagia transference cure.The rear pregnancy period is smooth, to expected date of confinement, and smooth delivery, neonate is without extremely.
Case 2: Wang, 28 years old, Distributions in Liaocheng of Shandong Province people.Spontaneous abortion 3 times, is conceived 50 ~ 60 days month.Patient on March 12nd, 2012 menolipsis in the time of 32 days, measure and undergo another pregnancy.Find after pregnancy, with the treatment of preventing miscarriage of the Chinese medicine preparation of this invention, to be used in conjunction for two courses for the treatment of, patient is without obvious threatened abortion symptom, drug withdrawal.Pregnancy period take always and lies up as main, is maintained until smoothly full-term pregnancy, then the healthy girl baby of smooth delivery one.
Case 3: Chen, 32 years old, people from Guan County, Shandong.Patient was admitted to hospital because of " menolipsis 62 days, colporrhagia companion stomachache 5 hours " on May 7th, 2012.Patient has Operation of Ectopic Pregnancy history 2 times, and rear obstruction of fallopian tube is infertile, this time for test-tube baby, become pregnant, and be twin pregnancy, fetus is comparatively valuable.After being admitted to hospital, start to take the Chinese medicine preparation in this invention, conditions of patients is stable gradually, and colporrhagia and colic symptoms fade away, apply 2 courses for the treatment of after drug withdrawal, there is not again stomachache and colporrhagia in the pregnancy period.December cesarean section delivery two boy babies then.

Claims (5)

1. a Chinese medicine preparation for the treatment of threatened abortion, is characterized in that: by following crude drug, made: 10 ~ 15 grams of Herba Taxillis, 10 ~ 20 grams of Semen Cuscutae, 10 ~ 15 grams of Radix Dipsaci, 10 ~ 20 grams, Colla Corii Asini, 10 ~ 15 grams of the Radixs Astragali, 10 ~ 15 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 4 ~ 9 grams of Radix Scutellariae, 10 ~ 20 grams of the Cortexs Eucommiae, 8 ~ 12 grams of Fructus Jujubaes.
2. a kind of Chinese medicine preparation for the treatment of threatened abortion according to claim 1, is characterized in that: by following crude drug, made: 12 grams of Herba Taxillis, 15 grams of Semen Cuscutae, 12 grams of Radix Dipsaci, 15 grams, Colla Corii Asini, 12 grams of the Radixs Astragali, 12 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 6 grams of Radix Scutellariae, 15 grams of the Cortexs Eucommiae, 10 grams of Fructus Jujubaes.
3. a kind of Chinese medicine preparation for the treatment of threatened abortion according to claim 1, is characterized in that: by following crude drug, made: 10 grams of Herba Taxillis, 10 grams of Semen Cuscutae, 10 grams of Radix Dipsaci, 10 grams, Colla Corii Asini, 10 grams of the Radixs Astragali, 10 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 4 grams of Radix Scutellariae, 10 grams of the Cortexs Eucommiae, 8 grams of Fructus Jujubaes.
4. a kind of Chinese medicine preparation for the treatment of threatened abortion according to claim 1, is characterized in that: by following crude drug, made: 15 grams of Herba Taxillis, 20 grams of Semen Cuscutae, 15 grams of Radix Dipsaci, 20 grams, Colla Corii Asini, 15 grams of the Radixs Astragali, 15 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 9 grams of Radix Scutellariae, 20 grams of the Cortexs Eucommiae, 12 grams of Fructus Jujubaes.
5. a kind of preparation method for the treatment of the Chinese medicine preparation of threatened abortion claimed in claim 1, is characterized in that: step is: get each crude drug and be put in marmite, add 5 ~ 8 times of water loggings not have, soak 1 ~ 1.5 hour, decoct 1 hour, filter, obtain.
CN201310669810.1A 2013-12-11 2013-12-11 Traditional Chinese medicine preparation for treating threatened abortion Pending CN103610779A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104606368A (en) * 2015-01-22 2015-05-13 张春敏 Traditional Chinese medicine composition for treating threatened abortion in first trimester of pregnancy
CN105748885A (en) * 2016-03-30 2016-07-13 广州暨南生物医药研究开发基地有限公司 Folium artemisiae argyi containing traditional Chinese medicine preparation for treating pregnancy sudden threatened abortion
CN108159110A (en) * 2018-02-09 2018-06-15 河南省中医院(河南中医药大学第二附属医院) Kidney-tonifying miscarriage-prevention plaster and preparation method thereof

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CN101632705A (en) * 2008-07-24 2010-01-27 夏范音 Chinese medicinal composition for boosting qi and quieting the fetus

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CN101632705A (en) * 2008-07-24 2010-01-27 夏范音 Chinese medicinal composition for boosting qi and quieting the fetus

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104606368A (en) * 2015-01-22 2015-05-13 张春敏 Traditional Chinese medicine composition for treating threatened abortion in first trimester of pregnancy
CN105748885A (en) * 2016-03-30 2016-07-13 广州暨南生物医药研究开发基地有限公司 Folium artemisiae argyi containing traditional Chinese medicine preparation for treating pregnancy sudden threatened abortion
CN108159110A (en) * 2018-02-09 2018-06-15 河南省中医院(河南中医药大学第二附属医院) Kidney-tonifying miscarriage-prevention plaster and preparation method thereof

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Application publication date: 20140305