CN103110798A - Chinese medicinal formula for treating menstrual disorder type infertility and preparation method thereof - Google Patents

Chinese medicinal formula for treating menstrual disorder type infertility and preparation method thereof Download PDF

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CN103110798A
CN103110798A CN2013100171937A CN201310017193A CN103110798A CN 103110798 A CN103110798 A CN 103110798A CN 2013100171937 A CN2013100171937 A CN 2013100171937A CN 201310017193 A CN201310017193 A CN 201310017193A CN 103110798 A CN103110798 A CN 103110798A
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radix
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fructus
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polygoni multiflori
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CN103110798B (en
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王丽赟
王彦菊
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Ran Hongtu
Zhejiang Hongsheng Technology Transfer Services Co ltd
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Abstract

The invention discloses a Chinese medicinal formula for treating menstrual disorder type infertility, which mainly comprises radix angelicae sinensis, radix rehmanniae preparata, white paeony root, radix pseudostellariae, plantago asiatica, China dodder, lycium barbarum, herb of shorthorned epimedium, rubus idaeus, cornus officinalis, radix polygoni multiflori, cornu cervi degelatinatum, cochinchinese asparagus root and fructus forsythia. The Chinese medicinal formula has the effects on enriching the blood and regulating menstruation, and has obvious cure effect on the menstrual disorder type infertility.

Description

A kind of Chinese medicinal formulae for the treatment of menoxenia type infertility and preparation method thereof
Technical field
The invention discloses a kind of Chinese medicinal formulae, especially treat Chinese medicinal formulae of menoxenia type infertility and preparation method thereof.Genus Chinese medicine field.
Background technology
Infertile medical definition is not take any contraceptives in 1 year, and sexual life is normal and there is no a successful pregnancy.Cause that infertile pathogenic factor is divided into male infertility and female acyesis, 1992 should classification in diagnosis and the extensive use for the treatment of infertility by World Health Organization (WHO).In developed country, the SF factor accounts for 37%, and male factor accounts for 8%; Both sides factor accounts for 35%, does not find that infertile (fertility) of reason accounts for 5%.The actual percentage of infertile independent primary factor is very large at difference research difference.Yet, one surpasses 20 and studies more widely infertile meta-analysis and find, primary etiological diagnosis is successively: infertile (17%) of ovulation failure (27%), dysspermatism (25%), oviduct abnormality (22%), unknown cause, endometriosis (5%) and other as infertile in immunology (4%).Factor is the cervix uteri factor in addition, comprises that accounting for all cervix uteri factors surpasses 5% cervical stenosis.Female acyesis is mainly with ovulation failure, the fallopian tube factor, and endometrium receptivity is main extremely, male infertility is mainly that spermatogenesis reaches the ejaculation obstacle extremely.
Menoxenia is a general designation, and it comprises that menstruation shifts to an earlier date, delays, irregularly, menorrhagia, very few etc.From the angle of modern medicine, menoxenia can be explained from reproductive endocrine, nerve, immune imbalance; From the angle of the traditional Chinese medical science, menoxenia liver,spleen,kidney functional disorder obstructed with insufficiency of vital energy and blood, visceral dysfunction, the especially traditional Chinese medical science is closely related.
Menoxenia type infertility refers to the long-term menstruation entanglement of women, and the matrimonial cohabitation person that do not become pregnant more than 3 years is one of gynecological clinic commonly encountered diseases.Menoxenia type infertility basis for estimation is: the long-term menstruation entanglement of women, matrimonial cohabitation was not become pregnant more than 3 years.Menstrual period or before or after, or the several months one to, or January number extremely, very amenorrhea.More or less mensis in amount, light or purple through color, or abdominal pain during menstruation, or stomachache before and after menstrual period.Or with adnexitis, fallopian tube enclosed mass, uterine hypoplasia, endometritis etc.
Chinese medicine thinks how not enough by natural endowment infertilitas feminis is, chamber does not save kidney essense and do not fill, and rushes conception vessel void, or deficiency of kidney yin, the uterus cold caused by deficiency, or plain body is weak, and deficiency of YIN-blood, vessels of the uterus lose supports; Or feelings will is not smooth, and depression of liver-QI is qi-blood disharmony; Or fat, the comfortable food greasy and surfeit flavour of plain body, deficiency of spleen-YANG and kidneyYANG accumulates living phlegm-damp, the mechanism of qi retardance, and punching is appointed obstructed; Or blood stasis condenses, and lump in the abdomen amasss in born of the same parents are medium and causes.The reason that causes female acyesis is many-sided, but many and menoxenia is in close relations, therefore, and traditional Chinese medical science opinion " female acyesis focuses on regulating menstruation ".
In the method for existing treatment menoxenia type infertility, Chinese patent CN03106271.7 discloses a kind of " Tiaojing Cuyun Chinese medicine and preparation method " by name in 2003, formed by Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Amomi, Flos Carthami, Radix Rehmanniae Preparata, Radix Notoginseng powder, Radix Bupleuri, the Radix Paeoniae Alba, prescription is simple, curative effect is single, and Radix Notoginseng, Flos Carthami in the side are the medical material that the anemia of pregnant woman is cautious use of, and pregnant front excessive use very easily is harmful to the health.
Summary of the invention
Present situation for existing treatment menoxenia type infertility deficiency, one of purpose of the present invention is to provide a kind of Chinese medicinal formulae for the treatment of menoxenia type infertility, have characteristics easy to operate, evident in efficacy, and its adopts comparatively common in the localities Chinese crude drug as raw material, with low cost.
Another object of the present invention is to provide the preparation method of above-mentioned Chinese medicinal formulae.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of Chinese medicinal formulae for the treatment of menoxenia type infertility, preferred scheme is taken off the primary raw material of stating weight proportion and is prepared from: Radix Angelicae Sinensis 6-12 part, Radix Rehmanniae Preparata 10-30 part, Radix Paeoniae Alba 10-15 part, Radix Pseudostellariae 10-30 part is (preferred, Radix Pseudostellariae 10.5-29 part), Semen Plantaginis 6-15 part, Semen Cuscutae 9-15 part, Fructus Lycii 6-12 part, Herba Epimedii 3-9 part, Fructus Rubi 5-10 part, Fructus Corni 6-12 part, Radix Polygoni Multiflori 6-12 part, Cornu Cervi Degelatinatum 9-15 part, Radix Asparagi 15-30 part, Fructus Forsythiae 6-15 part.
A kind of Chinese medicinal formulae for the treatment of menoxenia type infertility, the scheme that is more preferably is taken off the primary raw material of stating weight proportion and is prepared from: Radix Angelicae Sinensis 8-10 part, Radix Rehmanniae Preparata 15-25 part, Radix Paeoniae Alba 11-14 part, Radix Pseudostellariae 15-25 part, Semen Plantaginis 8-12 part, Semen Cuscutae 10-14 part, Fructus Lycii 8-10 part, Herba Epimedii 5-8 part, Fructus Rubi 7-9 part, Fructus Corni 8-11 part, Radix Polygoni Multiflori 8-10 part, Cornu Cervi Degelatinatum 10-14 part, Radix Asparagi 20-28 part, Fructus Forsythiae 8-12 part.
A kind of Chinese medicinal formulae for the treatment of menoxenia type infertility, best scheme is taken off the primary raw material of stating weight proportion and is prepared from: 9 parts of Radix Angelicae Sinensis, 20 parts of Radix Rehmanniae Preparata, 12 parts of the Radix Paeoniae Albas, 20 parts of Radix Pseudostellariaes, 10 parts of Semen Plantaginiss, 12 parts of Semen Cuscutae, 9 parts of Fructus Lycii, 7 parts of Herba Epimedii, 8 parts of Fructus Rubies, 10 parts of Fructus Corni, 9 parts of Radix Polygoni Multiflori, 12 parts of Cornu Cervi Degelatinatums, 25 parts of Radix Asparagis, 10 parts of Fructus Forsythiaes.
The preparation method of above-mentioned arbitrary Chinese medicinal formulae, preparation process is as follows:
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, then be placed in the pot fried dry, get Radix Paeoniae Alba, dry in the air cool standby;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside when all being sepia, the air dry of drying in the air is done, and gets Radix Polygoni Multiflori Preparata standby;
3. Cornu Cervi Degelatinatum is placed in that in marmite, intense fire is fried open, turns 20-45 at a simmer minute, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, the Fructus Forsythiae intense fire is fried open, turn 15-40 at a simmer minute, leach medicinal liquid;
4. recrement is watered again that intense fire is fried open, and turns 15-30 at a simmer minute, and twice medicinal liquid mixes.
3. the preparation method of above-mentioned Chinese medicinal formulae, step are placed in Cornu Cervi Degelatinatum that in marmite, intense fire is fried open, and turn 20-45 at a simmer minute (preferred 25-35 minute, be more preferably 30 minutes).
3. the preparation method of above-mentioned Chinese medicinal formulae, step turn 15-40 at a simmer minute (preferred 20-35 minute, be more preferably 25 minutes), leach medicinal liquid.
4. the preparation method of above-mentioned Chinese medicinal formulae, step turn 15-30 at a simmer minute (preferred 18-25 minute, be more preferably 20 minutes), and twice medicinal liquid mixes.
Using method: reach optimum therapeuticing effect for making the present invention, Chinese medicine decoction of the present invention, every day twice, in sooner or later taking half an hour after meal, cut out menstrual period.
This Chinese medicinal formulae is remarkable to menoxenia type infertility effect, the patient is pregnant nurse a baby youngster to do mother's right, also has menstruction regulating and pain relieving, is that menstruation recovery is normal, the conditioning complexion.Multiselect of the present invention is with local common medical material, and is cheap, alleviated patient's financial burden.
The pharmacological effect of each crude drug is respectively: 9 parts of Radix Angelicae Sinensis, 20 parts of Radix Rehmanniae Preparata, 12 parts of the Radix Paeoniae Albas, 20 parts of Radix Pseudostellariaes, 10 parts of Semen Plantaginiss, 12 parts of Semen Cuscutae, 9 parts of Fructus Lycii, 7 parts of Herba Epimedii, 8 parts of Fructus Rubies, 10 parts of Fructus Corni, 9 parts of Radix Polygoni Multiflori, 12 parts of Cornu Cervi Degelatinatums, 25 parts of Radix Asparagis, 10 parts of Fructus Forsythiaes.
Radix Angelicae Sinensis: sweet in the mouth, warm in nature, for enrich blood, emmenagogue.Promoting blood flow to regulate menstruation is arranged, moisturize laxation, the effect of the pain relieving of enriching blood is used for menoxenia, dysmenorrhea, all diseases of blood deficiency.
Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature.The yin nourishing of enriching blood, the effect of life essence-filling, marrow-benefitting is used for menoxenia, all diseases of blood deficiency, the hepatic and renal YIN deficiency.
The Radix Paeoniae Alba: bitter in the mouth, acid, cold nature.Radix Paeoniae Alba is made with yellow wine, and nourishing blood to suppress the hyperactive liver is arranged, slow middle pain relieving, and yin fluid astringing is received the effect of antiperspirant, is used for menoxenia, the disease of the deficiency of YIN.
Radix Pseudostellariae: sweet in the mouth, bitter in the mouth, property is flat.Replenishing QI to invigorate the spleen is arranged, and the effect of promoting the production of body fluid for nourishing the lung is used for insufficiency of the spleen body tired, and inappetence is weak after being ill, deficiency of both vital energy and Yin.
Semen Plantaginis: sweet in the mouth, cold nature.Clearing away heat and promoting diuresis is arranged, and the effect that eliminating dampness by diuresis is treating stranguria is used for the edema distension, the puckery pain of pyretic stranguria.
Semen Cuscutae: sweet in the mouth, warm in nature.Nourishing the liver and kidney is arranged, and antiabortive, the effect that makes eye bright is used for vaginal bleeding due to deficiency of the kidney during pregnancy, the diseases such as frequent fetal movement.
Fructus Lycii: sweet in the mouth, property is flat.Nourishing the liver and kidney is arranged, and the effect of replenishing vital essence to improve eyesight is used for the asthenia damage of essence, soreness of waist and knee joint, blood deficiency and yellow complexion.
Herba Epimedii: acrid in the mouth, sweet, warm in nature, kidney-replenishing is arranged, bone and muscle strengthening, the effect of wind-damp dispelling is used for the muscles and bones flaccidity soft, and is numb overcautious, rheumatic arthralgia.
Fructus Rubi: sweet in the mouth, property is flat.Invigorating the liver and kidney, supporing yang, the effect that makes eye bright are arranged.
Fructus Corni: sour in the mouth, slightly warm in nature.Liver and kidney tonifying is arranged, restrain astringent or styptic treatment for spontaneous sweating, the controlling nocturnal emission with astringent drugs reducing urination, the effect of pain relieving is used for soreness of the waist and knees, menoxenia.
Radix Polygoni Multiflori: sweet in the mouth, warm in nature.Radix Polygoni Multiflori Preparata forms with the decoction of black soybean Preparation process, and invigorating the liver and kidney is arranged, benefiting essence-blood, and the effect of bone and muscle strengthening is used for blood deficiency and yellow complexion, soreness of the waist and knees.
Cornu Cervi Degelatinatum: salty in the mouth, warm in nature.Warming the kidney to activate YANG is arranged, and anastaltic effect is used for the skin deficiency of the kidney yin, enuresis frequent micturition.
Radix Asparagi: sweet in the mouth, hardship, cold in nature.Nourishing YIN to relieve dryness is arranged, and the effect that lung heat clearing is promoted the production of body fluid is used for dryness of the lung dry cough, dry throat and mouth, dryness of the intestine constipation.
Fructus Forsythiae: bitter in the mouth, cold nature.Heat-clearing and toxic substances removing is arranged, and the effect of dispersing swelling and dissipating binds is used for epidemic febrile disease from the beginning of, warm joining the army.
Chinese medicinal formulae of the present invention is cured the disease with benefit based on the principle of Chinese medicine menoxenia type infertility.That selects in prescription is medical material of nourishing warm in nature, can not damage function of human body, in treatment menoxenia type infertility, can also reach strong health, improves the effect of immunity.
The specific embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1
Radix Angelicae Sinensis 6 grams, Radix Rehmanniae Preparata 10 grams, the Radix Paeoniae Alba 10 grams, Radix Pseudostellariae 10 grams, Semen Plantaginis 6 grams, Semen Cuscutae 9 grams, Fructus Lycii 6 grams, Herba Epimedii 3 grams, Fructus Rubi 5 grams, Fructus Corni 6 grams, Radix Polygoni Multiflori 6 grams, Cornu Cervi Degelatinatum 9 grams, Radix Asparagi 15 grams, Fructus Forsythiae 6 grams;
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, then be placed in the pot fried dry, get Radix Paeoniae Alba, dry in the air cool standby;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside when all being sepia, the air dry of drying in the air is done, and gets Radix Polygoni Multiflori Preparata standby;
3. Cornu Cervi Degelatinatum is placed in that in marmite, intense fire is fried open, turns 20 minutes at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, the Fructus Forsythiae intense fire is fried open, and turns 15 minutes at a simmer, leaches medicinal liquid;
4. recrement is watered again that intense fire is fried open, and turns 15 minutes at a simmer, and twice medicinal liquid mixes.
Embodiment 2
Radix Angelicae Sinensis 8 grams, Radix Rehmanniae Preparata 15 grams, the Radix Paeoniae Alba 11 grams, Radix Pseudostellariae 15 grams, Semen Plantaginis 8 grams, Semen Cuscutae 10 grams, Fructus Lycii 8 grams, Herba Epimedii 5 grams, Fructus Rubi 7 grams, Fructus Corni 8 grams, Radix Polygoni Multiflori 8 grams, Cornu Cervi Degelatinatum 10 grams, Radix Asparagi 20 grams, Fructus Forsythiae 8 grams;
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, then be placed in the pot fried dry, get Radix Paeoniae Alba, dry in the air cool standby;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside when all being sepia, the air dry of drying in the air is done, and gets Radix Polygoni Multiflori Preparata standby;
3. Cornu Cervi Degelatinatum is placed in that in marmite, intense fire is fried open, turns 25 minutes at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, the Fructus Forsythiae intense fire is fried open, and turns 20 minutes at a simmer, leaches medicinal liquid;
4. recrement is watered again that intense fire is fried open, and turns 18 minutes at a simmer, and twice medicinal liquid mixes.
Embodiment 3
Radix Angelicae Sinensis 10 grams, Radix Rehmanniae Preparata 25 grams, the Radix Paeoniae Alba 14 grams, Radix Pseudostellariae 25 grams, Semen Plantaginis 12 grams, Semen Cuscutae 14 grams, Fructus Lycii 10 grams, Herba Epimedii 8 grams, Fructus Rubi 9 grams, Fructus Corni 11 grams, Radix Polygoni Multiflori 10 grams, Cornu Cervi Degelatinatum 14 grams, Radix Asparagi 28 grams, Fructus Forsythiae 12 grams;
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, then be placed in the pot fried dry, get Radix Paeoniae Alba, dry in the air cool standby;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside when all being sepia, the air dry of drying in the air is done, and gets Radix Polygoni Multiflori Preparata standby;
3. Cornu Cervi Degelatinatum is placed in that in marmite, intense fire is fried open, turns 35 minutes at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, the Fructus Forsythiae intense fire is fried open, and turns 35 minutes at a simmer, leaches medicinal liquid;
4. recrement is watered again that intense fire is fried open, and turns 25 minutes at a simmer, and twice medicinal liquid mixes.
Embodiment 4
Radix Angelicae Sinensis 12 grams, Radix Rehmanniae Preparata 30 grams, the Radix Paeoniae Alba 15 grams, Radix Pseudostellariae 30 grams, Semen Plantaginis 15 grams, Semen Cuscutae 15 grams, Fructus Lycii 12 grams, Herba Epimedii 9 grams, Fructus Rubi 10 grams, Fructus Corni 12 grams, Radix Polygoni Multiflori 12 grams, Cornu Cervi Degelatinatum 15 grams, Radix Asparagi 30 grams, Fructus Forsythiae 15 grams;
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, then be placed in the pot fried dry, get Radix Paeoniae Alba, dry in the air cool standby;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside when all being sepia, the air dry of drying in the air is done, and gets Radix Polygoni Multiflori Preparata standby;
3. Cornu Cervi Degelatinatum is placed in that in marmite, intense fire is fried open, turns 45 minutes at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, the Fructus Forsythiae intense fire is fried open, and turns 40 minutes at a simmer, leaches medicinal liquid;
4. recrement is watered again that intense fire is fried open, and turns 30 minutes at a simmer, and twice medicinal liquid mixes.
Embodiment 5
Radix Angelicae Sinensis 9 grams, Radix Rehmanniae Preparata 20 grams, the Radix Paeoniae Alba 12 grams, Radix Pseudostellariae 20 grams, Semen Plantaginis 10 grams, Semen Cuscutae 12 grams, Fructus Lycii 9 grams, Herba Epimedii 7 grams, Fructus Rubi 8 grams, Fructus Corni 10 grams, Radix Polygoni Multiflori 9 grams, Cornu Cervi Degelatinatum 12 grams, Radix Asparagi 25 grams, Fructus Forsythiae 10 grams;
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, then be placed in the pot fried dry, get Radix Paeoniae Alba, dry in the air cool standby;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside when all being sepia, the air dry of drying in the air is done, and gets Radix Polygoni Multiflori Preparata standby;
3. Cornu Cervi Degelatinatum is placed in that in marmite, intense fire is fried open, turns 30 minutes at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, the Fructus Forsythiae intense fire is fried open, and turns 25 minutes at a simmer, leaches medicinal liquid;
4. recrement is watered again that intense fire is fried open, and turns 20 minutes at a simmer, and twice medicinal liquid mixes;
Using method: reach optimum therapeuticing effect for making the present invention, Chinese medicine decoction of the present invention, every day twice, in sooner or later taking half an hour after meal, cut out menstrual period.
Model case one
Liu XX, female, 35 years old, Sun Wu town Liu Yu booth village, Accessories during Binzhou Huimin County, Shandong Province.Symptom: the patient lives irregular because of in bar work, the smoking that is on the drink, and lethargy is tried out, and menoxenia, causes complexion dim, and marry did not all have pregnancy in rear 4 years always, was menoxenia type infertility after diagnosing.Sick age: 4 years.Examine the time: on August 21st, 2010; Chinese medicinal formulae of the present invention, every day twice, in sooner or later taking half an hour after meal, cut out menstrual period, took 1 month, and the mental status is clearly better; Took 2 months, complexion takes a turn for the better, and face begins ruddy; After taking medicine 3 months, menstrual blood volume is normal, and menstrual period are normal; After continuing to take 1 month, find conceivedly, drug withdrawal is given birth to a healthy boy baby smoothly afterwards, has no adverse reaction during taking Chinese medicinal formulae of the present invention.
Model case two
King XX, female, 28 years old, Accessories during Binzhou Boxing County, Shandong Province.Symptom: the patient never taked contraceptives after marrying in 24 years old, married 4 years, and is but never conceived.Learn that through careful inquiry patient's menstruation is always very irregular, after coming menophania from 15 years old, annual menstruation only comes 5 to 7 times, come about 3 days, and amount is few, before and after menstrual period and also there is no obvious malaise symptoms menstrual period at every turn.By careful inspection, be diagnosed as menoxenia type infertility.Sick age: 6 years.Examine the time: on April 12nd, 2011; Chinese medicinal formulae of the present invention, every day twice, in sooner or later taking half an hour after meal, cut out menstrual period, took 2 months, during menstrual period, continues 5 days, and menstrual blood volume is comparatively normal; Used 4 months, and recovered menstrual period normal; Continue decrement and consolidate use 1 month, every two days once, and in sooner or later taking half an hour after meal, cut out menstrual period, and drug withdrawal is always normal by the phase.The patient was in drug withdrawal after 2 months afterwards, and was conceived smoothly.
In order to verify the effect of Chinese medicinal formulae of the present invention, we have carried out the experiment (embodiment 5) of medicine, and accurately data have been carried out statistics and mathematical analysis.Concrete experimental result such as following table:
Figure 691795DEST_PATH_IMAGE001
Chinese medicinal formulae treatment menoxenia type infertility effect of the present invention is remarkable.Prove through clinical trial, total effective rate is 97%, cure rate is 85%, improve 17% than matched group Western medicine regulating menstruation class Drug therapy effective percentage, cure rate is high by 35%, and simple to operate, cheap, relapse rate is extremely low, the uncomfortable symptom of regulating menstruation fundamentally, and can nurse one's health health when curing the disease, increase autoimmunity, removing the slight illness of menoxenia type Sterility patient, is the comparatively desirable medicine for the treatment of menoxenia type infertility, is also to cause because of menoxenia type infertility the optimal path that infertile patient seeks to resolve safely infertile worry.

Claims (7)

1. a Chinese medicinal formulae for the treatment of menoxenia type infertility, is characterized in that, takes off the primary raw material of stating weight proportion and be prepared from: Radix Angelicae Sinensis 6-12 part, Radix Rehmanniae Preparata 10-30 part, Radix Paeoniae Alba 10-15 part, Radix Pseudostellariae 10-30 part, Semen Plantaginis 6-15 part, Semen Cuscutae 9-15 part, Fructus Lycii 6-12 part, Herba Epimedii 3-9 part, Fructus Rubi 5-10 part, Fructus Corni 6-12 part, Radix Polygoni Multiflori 6-12 part, Cornu Cervi Degelatinatum 9-15 part, Radix Asparagi 15-30 part, Fructus Forsythiae 6-15 part.
2. Chinese medicinal formulae according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and be prepared from: Radix Angelicae Sinensis 8-10 part, Radix Rehmanniae Preparata 15-25 part, Radix Paeoniae Alba 11-14 part, Radix Pseudostellariae 15-25 part, Semen Plantaginis 8-12 part, Semen Cuscutae 10-14 part, Fructus Lycii 8-10 part, Herba Epimedii 5-8 part, Fructus Rubi 7-9 part, Fructus Corni 8-11 part, Radix Polygoni Multiflori 8-10 part, Cornu Cervi Degelatinatum 10-14 part, Radix Asparagi 20-28 part, Fructus Forsythiae 8-12 part.
3. Chinese medicinal formulae according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and be prepared from: 9 parts of Radix Angelicae Sinensis, 20 parts of Radix Rehmanniae Preparata, 12 parts of the Radix Paeoniae Albas, 20 parts of Radix Pseudostellariaes, 10 parts of Semen Plantaginiss, 12 parts of Semen Cuscutae, 9 parts of Fructus Lycii, 7 parts of Herba Epimedii, 8 parts of Fructus Rubies, 10 parts of Fructus Corni, 9 parts of Radix Polygoni Multiflori, 12 parts of Cornu Cervi Degelatinatums, 25 parts of Radix Asparagis, 10 parts of Fructus Forsythiaes.
4. the preparation method of according to claim 1-3 arbitrary described Chinese medicinal formulaes, is characterized in that, preparation process is as follows:
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, then be placed in the pot fried dry, get Radix Paeoniae Alba, dry in the air cool standby;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside when all being sepia, the air dry of drying in the air is done, and gets Radix Polygoni Multiflori Preparata standby;
3. Cornu Cervi Degelatinatum is placed in that in marmite, intense fire is fried open, turns 20-45 at a simmer minute, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, the Fructus Forsythiae intense fire is fried open, turn 15-40 at a simmer minute, leach medicinal liquid;
4. recrement is watered again that intense fire is fried open, and turns 15-30 at a simmer minute, and twice medicinal liquid mixes.
5. preparation method according to claim 4, is characterized in that, 3. step is placed in Cornu Cervi Degelatinatum that in marmite, intense fire is fried open, and turns 20-45 at a simmer minute (preferred 25-35 minute, be more preferably 30 minutes).
6. preparation method according to claim 4, is characterized in that, 3. step turns 15-40 at a simmer minute (preferred 20-35 minute, be more preferably 25 minutes), leaches medicinal liquid.
7. preparation method according to claim 4, is characterized in that, 4. step turns 15-30 at a simmer minute (preferred 18-25 minute, be more preferably 20 minutes), and twice medicinal liquid mixes.
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