CN103599522A - Traditional Chinese medicine preparation for treating herpes zoster - Google Patents
Traditional Chinese medicine preparation for treating herpes zoster Download PDFInfo
- Publication number
- CN103599522A CN103599522A CN201310460653.3A CN201310460653A CN103599522A CN 103599522 A CN103599522 A CN 103599522A CN 201310460653 A CN201310460653 A CN 201310460653A CN 103599522 A CN103599522 A CN 103599522A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine preparation
- herpes zoster
- preparation
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine preparation for treating herpes zoster. The preparation is prepared from radices trichosanthis (root of Chinese trichosanthes), pokeberry root, a Chinese angelica composite extract and a solvent. The preparation comprises following main component by weight: 6.9-7.6% of pokeberry polysaccharides, 1.7-2.1% of pokeberry proteins, 0.5-1.0% of trichosanthin, 0.64-0.7% of a butylidene phthalide, 0.3-0.33% of ferulic acid and 88.27-89.96% of medical turpentine. The preparation is prepared by processing, extracting, bottling and sealing for further use. The traditional Chinese medicine preparation is a novel plant-source medicament. Raw materials for producing the traditional Chinese medicine preparation are renewable. The traditional Chinese medicine preparation has the advantages of small dosage, long lasting period of the medicine, low cost, and the like. The traditional Chinese medicine preparation not only has good treating effects for the herpes zoster, but also is nontoxic, safe, direct and efficient, and the preparation is simple in preparing technology and saving in cost.
Description
Technical field
The present invention relates to a kind of preparation and application process for the treatment of the Chinese medicine preparation of herpes zoster, be particularly applicable to treat taped blister examine disease.The virus of said preparation in can passivation skin surface herpes, suppress its breeding and there is induction skin virus to be produced to the effect of resistance, and can promote that the open sore part heals as early as possible more afterwards.Through medication in 10 days, can effectively treat herpes zoster.
Background technology
Herpes zoster is the actute infection dermatoses being caused by varicella zoster virus.This virus has neurotropism, after infection, can hide for a long time in the neuron of spinal nerves posterior root ganglion, when lower for the resistance or tired, infection, flu, virus can regrow breeding, and move to skin along nerve fiber, make nerve and the skin of being invaded produce strong inflammation.The feature that erythra generally has one-sided property and distributes by nerve segment, is comprised of the herpes that collects bunch property, and with pain; Age is larger, and neuralgia is heavier.Primary disease is apt to occur in adult, day by day comes into one's own.
In China's Chinese Traditional Medicine and folk medicine, containing very abundant antiviral natural active substance, is the valuable source of exploitation antivirus inhibitor.Because effect feature and the chemical pesticide of development in research of natural antiphytoviral substances has a great difference, only know about its effect feature and grasp correct using method, could bring into play better its preventive and therapeutic effect to virosis.More than 90% plant virus belongs to RNA viruses, therefore from mechanism top sieve, selects rna synthesis inhibitor or protein synthesis inhibitor to be a kind of research method of shooting the arrow at the target.We think from new native compound or various heterocycles and substituted heterocycle are introduced to the native compound reactive precursor the having now found that eco-friendly antivirus inhibitor of developing surely novel, efficient, low toxicity, low-residual that gets on.
At present, the treatment of herpes zoster be mainly chemicals in conjunction with hormonotherapy, although it has played certain curative effect, brought again side effect simultaneously, hormone abuse reduces resistance of human body, chemicals metabolism is slow, and human body is had to certain harm.
Chinese medicine preparation of the present invention is a kind of new medicine based on herbs, has feature nontoxic, instant effect.And the raw material of producing is renewable.There is the advantages such as dosage is few, the lasting period of medicine is long, with low cost.
Summary of the invention
The plant source preparation and the methods for making and using same thereof that the object of this invention is to provide the actute infection dermatoses that a kind of low cost, highly active anti-herpes zoster virus cause, effectively to treat herpesvirus dermatosis.
Ribosome inactivating protein (RibosomeInactivatingProteins, RIPs) be the single-minded synthetic proteotoxin of eukaryotic cell ribosome inhibiting protein that acts on of a class, be divided into strand SCRIPs and double-stranded RIPs, the antiviral activity .RIPs with wide spectrum can only enter in the abnormal cells such as viral infection by selectivity, and it is less to normal host cell infected, they except the plant virus to different effectively, in vitro tests shows also can suppress influenza virus, encephalitis b virus, Coxsackie virus, Measles virus, herpes simplex virus, poliovirus, hepatitis virus and adenovirus etc., polysaccharide (Polysaccharides, PS) be a class macromolecular substances that is extensively present in occurring in nature, also be one of teleorganic composition. large quantity research shows, many polysaccharide to various virus as HIV (human immunodeficiency virus) (HIV-1), herpes simplex virus, cytomegalovirus, influenza virus, cryptomere gastritis virus, rous sarcoma virus, black sarcoma virus etc. has inhibitory action, cyclobutenyl phthalein lactone is distributed widely in Radix Angelicae Sinensis, has cholinolytic, the effects such as relieving spasm to stop pain medicine.Ferulic acid has antiplatelet aggregation, suppresses platelet 5-HT and discharges, and suppresses the generation of platelet thrombus element a2 (txa2), strengthens prostaglandin active, analgesia, the effects such as alleviating vascular spasm.In human body, can play effect vigorous and graceful and protection skin simultaneously.
The present invention is exactly by extracting in Radix Phytolaccae, pinaster branch and leaf the antiviral ingredients such as vegetable protein, polysaccharide, triterpenoid saponin, is aided with suitable solvent and a kind of plant source disease-resistant toxin preparation of developing.
Its technical solution is as follows: a kind of Chinese medicine preparation for the treatment of herpes zoster, and formulated by composite extract and the solvent of Radix Trichosanthis (radices trichosanthis), Radix Phytolaccae, Radix Angelicae Sinensis, its predominant quantity percentage ratio is:
Above-mentioned preparation, its preparation method is shown in accompanying drawing.By Radix Trichosanthis (radices trichosanthis), Radix Phytolaccae, Radix Angelicae Sinensis, by weight 1:1:1, mix, processing is broken into granule (pulverizer processing), cross 20 sieve meshes, the extraction still of 25kg granule being put into Multifunctional Chinese medicine extraction equipment extracts, and adds 75 liter of 75% medical ethanol, the temperature steaming and decoctings of 82-85 ℃ after 2.0 hours, reconcentration 1 hour, Radix Trichosanthis (radices trichosanthis), Radix Phytolaccae, Radix Angelicae Sinensis composite extract condensed cream and crystalline solid; Add medical Oleum Terebinthinae, mix homogeneously, becomes the Chinese medicine preparation for the treatment of belt shape herpes again, bottling sealing.
The Chinese medicine preparation of above-mentioned said treatment herpes zoster, its using method comprises the steps: that its using method comprises the steps: that just mixed liquor spreads upon on the skin of herpes zoster uniformly, uses 10 days continuously.
Beneficial effect of the present invention:
The present invention has good effect to treatment herpes zoster.Not only therapeutic effect is good, and is free from side effects, with low cost, preparation technology is simple, safety, directly, environmental protection, efficient.The Chinese medicine preparation that the present invention treats herpes zoster can be used for all kinds of viral dermatosiies, by early stage medication, can thoroughly cure all kinds of viral dermatosiies.
The specific embodiment
Embodiment
The Chinese medicine preparation for the treatment of herpes zoster of the present invention, the weight percent of its each composition is such as table 1:
Table 1: each component accounts for finished weight percentage ratio
Its preparation method is as follows:
(1) by Radix Trichosanthis (radices trichosanthis), Radix Phytolaccae, Radix Angelicae Sinensis, by weight 1:1:1, mix, processing is broken into granule (pulverizer processing), crosses 20 sieve meshes, and the extraction still of 25kg granule being put into Multifunctional Chinese medicine extraction equipment extracts;
(2) add 75 liters of 75% medical ethanols, 82-85 ℃ of temperature steaming and decoctings are after 2.0 hours, and reconcentration 1 hour, is condensed into condensed cream and crystalline solid, i.e. Radix Trichosanthis (radices trichosanthis), Radix Phytolaccae, Radix Angelicae Sinensis composite extract;
(3) get extract and add medical Oleum Terebinthinae again, mix homogeneously, becomes the Chinese medicine preparation for the treatment of belt shape herpes.
(4) respectively fill: by treatment herpes zoster preparation 100ml pack in plastic bottle, seal stand-by.
The application technology of anti-virus formulation of the present invention, below step:
Mixed liquor is spread upon uniformly on the skin of herpes zoster, use continuously 10 days.
Therapeutic test
2011-2013 in Tai’an each community clinic portion Patients with Herpes Zoster is freely tested.Have 126 routine volunteers and test, take acyclovir ointment as control drug, choose at random 30 routine patients and carry out controlled trial.Spread upon on the skin of herpes zoster, use continuously 10 days.10 days " Invest, Then Investigate " state of an illness.The results are shown in Table 2.
Table 2: the therapeutic effect of Chinese medicine preparation of the present invention
| ? | Test number | Healing number | Cure rate (%) |
| Chinese medicine preparation of the present invention | 96 | 92 | 95.83 |
| Acyclovir ointment | 30 | 22 | 73.33 |
As can be seen from Table 2, Chinese medicine preparation of the present invention has good therapeutic effect, and average cure rate is: 95.83%, contrast 20% acyclovir ointment, and average cure rate is: 73.33%.Comprehensive analysis, Chinese medicine preparation of the present invention has good therapeutic effect.And, do not find any side effect.
Claims (5)
1. treat a Chinese medicine preparation for herpes zoster, formulated by composite extract and the solvent of Radix Trichosanthis (radices trichosanthis), Radix Phytolaccae, Radix Angelicae Sinensis, wherein the percentage by weight of each component is:
2. treating as claimed in claim 1 the Chinese medicine preparation of herpes zoster, it is characterized in that said solvent, is medical Oleum Terebinthinae.
3. treat as claimed in claim 1 the Chinese medicine preparation of herpes zoster, its preparation method, by Radix Trichosanthis (radices trichosanthis), Radix Phytolaccae, Radix Angelicae Sinensis, by weight 1:1:1, mix, processing is broken into granule (pulverizer processing), cross 20 sieve meshes, the extraction still of 25kg granule being put into Multifunctional Chinese medicine extraction equipment extracts, add 75 liter of 75% medical ethanol, the temperature steaming and decoctings of 82-85 ℃ after 2.0 hours, reconcentration 1 hour, Radix Trichosanthis (radices trichosanthis), Radix Phytolaccae, Radix Angelicae Sinensis composite extract condensed cream and crystalline solid; Add medical Oleum Terebinthinae, mix homogeneously, becomes the Chinese medicine preparation for the treatment of belt shape herpes again, bottling sealing.
4. treat as claimed in claim 1 the Chinese medicine preparation of herpes zoster, its using method comprises the steps: that just mixed liquor spreads upon on the skin of herpes zoster uniformly, uses continuously 10 days.
5. pollen (radices trichosanthis), Radix Phytolaccae, Radix Angelicae Sinensis are being treated the application of the Chinese medicine preparation of herpes zoster.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310460653.3A CN103599522A (en) | 2013-09-18 | 2013-09-18 | Traditional Chinese medicine preparation for treating herpes zoster |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310460653.3A CN103599522A (en) | 2013-09-18 | 2013-09-18 | Traditional Chinese medicine preparation for treating herpes zoster |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103599522A true CN103599522A (en) | 2014-02-26 |
Family
ID=50117828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310460653.3A Pending CN103599522A (en) | 2013-09-18 | 2013-09-18 | Traditional Chinese medicine preparation for treating herpes zoster |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103599522A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106176860A (en) * | 2016-08-31 | 2016-12-07 | 吴长来 | A kind of Chinese medicine for treating herpes zoster |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264156A (en) * | 2008-04-01 | 2008-09-17 | 王英珍 | Externally-applied medicament for treating shingles |
| CN101716207A (en) * | 2009-12-31 | 2010-06-02 | 胡井夫 | Chinese medicine pigmentum for treating shingles and preparation method thereof |
| CN102283925A (en) * | 2011-09-02 | 2011-12-21 | 连秀娜 | Traditional Chinese medicine for treating neurodynia resulted from herpes zoster |
| CN102342990A (en) * | 2011-09-28 | 2012-02-08 | 李军 | Chinese medicinal composition for treating herpes zoster |
-
2013
- 2013-09-18 CN CN201310460653.3A patent/CN103599522A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264156A (en) * | 2008-04-01 | 2008-09-17 | 王英珍 | Externally-applied medicament for treating shingles |
| CN101716207A (en) * | 2009-12-31 | 2010-06-02 | 胡井夫 | Chinese medicine pigmentum for treating shingles and preparation method thereof |
| CN102283925A (en) * | 2011-09-02 | 2011-12-21 | 连秀娜 | Traditional Chinese medicine for treating neurodynia resulted from herpes zoster |
| CN102342990A (en) * | 2011-09-28 | 2012-02-08 | 李军 | Chinese medicinal composition for treating herpes zoster |
Non-Patent Citations (2)
| Title |
|---|
| 史霖等: ""植物多糖的提取分离及应用研究进展"", 《农业基础科学》, vol. 23, no. 9, 30 September 2007 (2007-09-30) * |
| 尹明标等: ""商陆蛋白质的纯化及其抗单纯疱疹病毒（Ⅱ型）活性的研究"", 《病毒学报》, vol. 1, no. 2, 24 December 1985 (1985-12-24) * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106176860A (en) * | 2016-08-31 | 2016-12-07 | 吴长来 | A kind of Chinese medicine for treating herpes zoster |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102416023B (en) | Periplaneta Americana L. gel externally applied medicinal composition and preparation method and use thereof in preparation of externally applied medicines for treating scalding | |
| CN102861274B (en) | External use traditional Chinese medicine for treating eczema | |
| CN103417949A (en) | TCM composition for treatment of male sterility | |
| CN103599522A (en) | Traditional Chinese medicine preparation for treating herpes zoster | |
| CN103054985B (en) | Pure Chinese medicinal composition for treating red fin disease of eels and preparation method of pure Chinese medicinal composition | |
| CN105233152A (en) | Traditional Chinese medicinal composition having function of relieving pain and preparation method of traditional Chinese medicinal composition | |
| CN104173569A (en) | Drug for treating burn and scald | |
| CN109172749A (en) | A kind of liquid medicine and preparation method thereof for treating gout | |
| CN106797958A (en) | A kind of macro fungi preparation of Antiphytoviral and preparation method thereof | |
| CN109172637A (en) | A kind of preparation method of capsule that treating rheumatism | |
| CN111388367B (en) | Composition for inhibiting melanin at multiple target points, preparation method and application of composition in cosmetics | |
| CN110613841B (en) | Snailase traditional Chinese medicine ointment for treating psoriasis and preparation method thereof | |
| CN101485709B (en) | Chinese medicinal composition for treating zoster and preparation thereof | |
| CN107050126A (en) | Chinese drugs agentia for treating acne | |
| CN105287977A (en) | Sweet basil herb and aloe composition and preparation as well as preparation method and application of sweet basil herb and aloe composition | |
| CN103585458A (en) | Traditional Chinese medicine for treating shingles | |
| CN115025119A (en) | Ointment for treating herpes zoster and herpes and preparation method thereof | |
| CN108079218A (en) | Chinese medicine composition for treating skin stubborn dermatitis and preparation method thereof | |
| Obiandu et al. | Scholars Journal of Applied Medical Sciences | |
| CN104922362A (en) | Traditional Chinese medicine composite for preventing and treating local child chickenpox and preparation method thereof | |
| CN103055038A (en) | Pure Chinese medicinal composition for treating bee chalkbrood disease and preparation method thereof | |
| CN109512975A (en) | For the Chinese medicine composition and its preparation of shingles zoster, preparation method and purposes | |
| CN109125679A (en) | It is a kind of to treat dermopathic strong medicine treating skin disease | |
| CN107929678A (en) | One kind prevention arthritic pure Chinese medicine paste of chicken | |
| CN103494981A (en) | Chinese patent medicine for treating shingles |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140226 |