CN103599509B - Traditional Chinese medicine composition for treating typhoid floating Yang - Google Patents
Traditional Chinese medicine composition for treating typhoid floating Yang Download PDFInfo
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- CN103599509B CN103599509B CN201310583020.1A CN201310583020A CN103599509B CN 103599509 B CN103599509 B CN 103599509B CN 201310583020 A CN201310583020 A CN 201310583020A CN 103599509 B CN103599509 B CN 103599509B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating typhoid floating Yang, relating to the technical field of Chinese herbal medicine. The traditional Chinese medicine composition is prepared from the following raw pharmaceutical materials in weight: 90-110g of fistular onion stalk, 19-21g of cooked aconite root, 9-11g of cinnamon, 9-11g of dried ginger, 9-11g of red ginseng, 4-6g of schisandra fruit, 9-11g of ophiopogon root, 2-4 Chinese dates, 19-21g of astragalus root, 6-8g of calcined keel, 7-9g of calcined oyster shell, 9-11g of tuckahoe, 9-11g of fried white atractylodes rhizome, 5-7g of prepared pinellia tuber, 9-11g of cassia twig, 14-16g of tortoise plastron, 14-16g of turtle shell, 9-11g of raw white peony root and 9-11g of prepared rehmannia root. The traditional Chinese medicine composition has the characteristics of easiness in material obtaining, simplicity in preparation, low cost, reasonable compatibility and the like, is small in dosage, low in content of harmful ingredients and remarkable in curative effect, and is free from toxic and side effects.
Description
Technical field
The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of Chinese medicine composition being used for the treatment of typhoid fever floating YANG disease.
Background technology
Floating YANG, card name.Refer to that patient two cheekbone color is light red as adornment, the disease of keeping on vacillating.1. because lower first void declines more than, very cold upper pseudo-heat under kidney-Yang is floating more caused." Treatise on Febrile Diseases distinguishes that JUE YIN syndrome arteries and veins is demonstrate,proved and controls ": " its floating YANG on the face, dificiency in lower-JIAO therefore also." normal companion sees that mouth and nose are defeated in battle, or dry mouth tooth is floating, sufficient shin cold of the limbs, floating and large pulse, the inanition of pressing is unable, or fine wild etc.Control should QI invigorating, to hold back sun, admittedly take off be main.Urgent need shenfu decoction, Bai Tongtang, decoction of ten powerful tonics, Bai-Wei-Dihuang soup etc.See excessive YIN keeping YANG externally bar.2. also can caused by YANG QI stagnating on the exterior." miscellaneous diseases source and course rhinoceros light up facial source of disease stream ": " floating YANG on the face disease, one rushed because of floating fire, and one because stagnation of YANG QI is in table.It is because of stagnation of YANG QI person, and when delivering, in purgative shouldn’t be adopted, what fire stagnation was then sent out is also." treatise on Febrile Diseases cloud: " few positive disease, deadly cold hand and foot, its people's flushed face." negative and positive all decline in patient's kidney, haze four cloth, kidney-Yang leaps, discordance between water(the kidney)and fire(the heart), and the mind is without attached, therefore coma, flushed complexion is tender as gay feminine attire, deadly cold hand and foot; The exciting diseases caused by retention of fluid of cold-evil, therefore expectorant sound is filtered; Tongue is black, and thirsty few drink is that kidney-Yang declines, as at the bottom of still without firewood, body fluid can not ascension.
Summary of the invention
It is high that technical problem to be solved by this invention is to provide a kind of cure rate, the safe and reliable Chinese medicine composition being used for the treatment of typhoid fever floating YANG disease.
Technical problem to be solved by this invention realizes by the following technical solutions:
Be used for the treatment of a Chinese medicine composition for typhoid fever floating YANG disease, the medicament be made up of the crude drug of following weight,
Bulbus Allii Fistulosi 90-110g, Radix Aconiti Lateralis Preparata 19-21g(are decocted first), Cortex Cinnamomi 9-11g, Rhizoma Zingiberis 9-11g, Radix Ginseng Rubra 9-11g, Fructus Schisandrae Chinensis 4-6g, Radix Ophiopogonis 9-11g, Fructus Jujubae 2-4 piece, Radix Astragali 19-21g, Os Draconis (calcined) 6-8g, Concha Ostreae (calcined) 7-9g, Poria 9-11g, Rhizoma Atractylodis Macrocephalae (parched) 9-11g, Rhizoma Pinelliae Preparatum 5-7g, Ramulus Cinnamomi 9-11g, Carapax et Plastrum Testudinis 14-16g, Carapax Trionycis 14-16g, Radix Paeoniae Alba 9-11g, Radix Rehmanniae Preparata 9-11g.
The preferred weight of each component is:
Bulbus Allii Fistulosi 100g, Radix Aconiti Lateralis Preparata 20g(are decocted first), Cortex Cinnamomi 10g, Rhizoma Zingiberis 10g, Radix Ginseng Rubra 10g, Fructus Schisandrae Chinensis 5g, Radix Ophiopogonis 10g, 3 pieces, Fructus Jujubae, Radix Astragali 20g, Os Draconis (calcined) 7g, Concha Ostreae (calcined) 8g, Poria 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Rhizoma Pinelliae Preparatum 6g, Ramulus Cinnamomi 10g, Carapax et Plastrum Testudinis 15g, Carapax Trionycis 15g, Radix Paeoniae Alba 10g, Radix Rehmanniae Preparata 10g.
Crude drug used by the present invention can be bought from common Chinese shop and obtain, and its specification meets national Chinese crude drug standard.
Chinese medicine composition of the present invention can add various adjuvants required when preparing different dosage form, such as disintegrating agent, lubricant, adhesive etc., the conventional oral formulations of any one is prepared into the method for Chinese medicinal of routine, wherein, described oral formulations can be decoction, pill, capsule or tablet.
Another object of the present invention is to provide a kind of method preparing the present composition, comprises the steps,
1) each crude drug is taken by prescription weight number;
2) above-mentioned each taste material medicine is mixed being placed in marmite adds water did not have powder, soak after 20 ~ 40 minutes, with slow fire boiling, renew after boiling and decoct 30 minutes, decoct three times altogether, merges three decocting liquids filtrations, obtain decoction.
Bulbus Allii Fistulosi dredging QI between the upper and lower, fire has home to return to, and the anxious above inducing vomiting that returns is empty positive;
Radix Ginseng Rubra, Radix Aconiti Lateralis Preparata, Os Draconis, Concha Ostreae, Rhizoma Pinelliae righting sun return to rescue and mould, and daybreak expectorant takes off admittedly;
Carapax et Plastrum Testudinis, Carapax Trionycis, the Radix Paeoniae Alba, Fructus Jujubae sour and sweet drugs can transforme into YIN, to free fire, take the photograph with subduing the hyperactivity of YANG and receive, hide for expensive, and latent then body is good for, and firmly gets " YIN and YANG in a relative equilibrium, life activities being normally maintained ".
The strange difficulty of this card takes Radix Aconiti Lateralis Preparata patient, Rhizoma Zingiberis is not known acid and knows sweet, can see very clearly dirty very cold, YANG failing to warm spleen-YANG, and deficiency of spleen-YANG, and after taking medicine, guiding fire to origin, adjust the dual power of negative and positive principles, in kidney, negative and positive tend to balance, and sickly accuse suddenly.
Usage and consumption:
The dosage of medicine of the present invention depends on concrete dosage form, and the factor such as the age of patient, body weight, health status.Instruction: every day 1 dose, decocting, morning, noon and afternoon sub-service.
Medicated diet prepared by the present invention has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and disease therapy, drops into the use link of disease therapy provide science and objective foundation to this medicine.Its test method and result of the test are distinguished as follows:
1. the medicated diet that couple the present invention boils carries out animal acute toxicity test:
Medicine: the decoction boiled by prescription of the present invention, saves backup in refrigerator, is provided by The First Affiliated Hospital of Anhui College of Traditional Chinese Medicine.
Experimental animal: white mice, body weight is at 30-50g, and male and female Stochastic choice, is provided by Medical University Of Anhui.
Method and result: get white mice 50, be divided into 5 groups, often organize 10, hungry 15 hours, fill with medicine feed thing by every only each 5ml, in 24 hours, fill with medicine feed thing respectively 1,2,3,4,5 times for the 1st, 2,3,4,5 group, observe 5 days, white mice is movable normal, non-toxic reaction, without dead.Wherein white mice dosage is by kg body weight medicine calculation, shows that oral liquid is without acute toxicity, clinical medicine dose safety.
2. the decoction that couple the present invention boils carries out long-term toxicity test for animals:
Experimental animal: rat, body weight, at 120-130g, all selects male white rat, is provided by Medical University Of Anhui.
Method and result: get rat 50, be divided into 5 groups, often organize 10, wherein the 1st, 2, 3, 4 groups as administration group, often organize and fill with medicine feed thing 4ml respectively, 6ml, 8ml, 10ml, 5th group of diet as a control group, once a day, continuous irrigation is fed 90 days, survey body weight, 24 hours sacrificed by decapitation after last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the change of tissues observed form, observe the effect of dosage, observe diet, movable change, experiment proves that administration group compares without significant change with matched group, visible by the dosage equal non-toxic reaction of kg body weight calculating relative to clinical 50-200 times, a kind of safe drugs.
In order to verify clinical efficacy, this prescription Jieshou City institute of traditional Chinese medicine tries out, by random selecting wherein cavernous pulmonary tuberculosis 40 example (6 examples of being in hospital, outpatient service 34 example);
1, Therapeutic Method
According to drug ratios of the present invention, take raw material (dose), obtain medicinal liquid according to the method for usually boiling medicine, every day potion, the morning, noon and afternoon service once, one week course for the treatment of.
2, clinical data
This organizes in 40 examples, man 24 example, female 16 example: 11 ~ 20 years old 6 age example, 21 ~ 40 years old 14 example, 41 ~ 60 years old 16 example, more than 60 years old 4 example.Tcm diagnosis belongs to typhoid fever syndrome of floating YANG.
3, therapeutic outcome
Effective 29 examples (god is clear, and language is answered freely, the extremities being warm and), effective 9 examples (the extremities being warm), invalid 2 examples, total effective rate reaches 95%.
The invention has the beneficial effects as follows: the present invention draws materials easily, makes the features such as simple, with low cost, compatibility is reasonable, and taking dose is little, and Harmful ingredient content is low, has no side effect, evident in efficacy.
Detailed description of the invention
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
Take each crude drug by following weight number: Bulbus Allii Fistulosi 100g, Radix Aconiti Lateralis Preparata 20g(are decocted first), Cortex Cinnamomi 10g, Rhizoma Zingiberis 10g, Radix Ginseng Rubra 10g, Fructus Schisandrae Chinensis 5g, Radix Ophiopogonis 10g, 3 pieces, Fructus Jujubae, Radix Astragali 20g, Os Draconis (calcined) 7g, Concha Ostreae (calcined) 8g, Poria 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Rhizoma Pinelliae Preparatum 6g, Ramulus Cinnamomi 10g, Carapax et Plastrum Testudinis 15g, Carapax Trionycis 15g, Radix Paeoniae Alba 10g, Radix Rehmanniae Preparata 10g.
Above-mentioned each taste material medicine is mixed being placed in marmite adds water did not have powder, soak after 20 ~ 40 minutes, with slow fire boiling, renew after boiling and decoct 30 minutes, decoct three times altogether, merges three decocting liquids filtrations, obtain decoction.Instruction: every day 1 dose, decocting, morning, noon and afternoon sub-service.
Embodiment 2
Take each crude drug by following weight number: Bulbus Allii Fistulosi 110g, Radix Aconiti Lateralis Preparata 21g(are decocted first), Cortex Cinnamomi 11g, Rhizoma Zingiberis 11g, Radix Ginseng Rubra 11g, Fructus Schisandrae Chinensis 6g, Radix Ophiopogonis 11g, 4 pieces, Fructus Jujubae, Radix Astragali 21g, Os Draconis (calcined) 8g, Concha Ostreae (calcined) 9g, Poria 11g, Rhizoma Atractylodis Macrocephalae (parched) 11g, Rhizoma Pinelliae Preparatum 7g, Ramulus Cinnamomi 11g, Carapax et Plastrum Testudinis 16g, Carapax Trionycis 16g, Radix Paeoniae Alba 11g, Radix Rehmanniae Preparata 11g.
Above-mentioned each taste material medicine is mixed being placed in marmite adds water did not have powder, soak after 20 ~ 40 minutes, with slow fire boiling, renew after boiling and decoct 30 minutes, decoct three times altogether, merges three decocting liquids filtrations, obtain decoction.Instruction: every day 1 dose, decocting, morning, noon and afternoon sub-service.
Embodiment 3
Take each crude drug by following weight number: Bulbus Allii Fistulosi 90g, Radix Aconiti Lateralis Preparata 19g(are decocted first), Cortex Cinnamomi 9g, Rhizoma Zingiberis 9g, Radix Ginseng Rubra 9g, Fructus Schisandrae Chinensis 4g, Radix Ophiopogonis 9g, 2 pieces, Fructus Jujubae, Radix Astragali 19g, Os Draconis (calcined) 6g, Concha Ostreae (calcined) 7g, Poria 9g, Rhizoma Atractylodis Macrocephalae (parched) 9g, Rhizoma Pinelliae Preparatum 5g, Ramulus Cinnamomi 9g, Carapax et Plastrum Testudinis 14g, Carapax Trionycis 14g, Radix Paeoniae Alba 9g, Radix Rehmanniae Preparata 9g.
Above-mentioned each taste material medicine is mixed being placed in marmite adds water did not have powder, soak after 20 ~ 40 minutes, with slow fire boiling, renew after boiling and decoct 30 minutes, decoct three times altogether, merges three decocting liquids filtrations, obtain decoction.Instruction: every day 1 dose, decocting, morning, noon and afternoon sub-service.
Model case
Case 1
Liu, man, 62, retired cadre, people from Jieshou City, Anhui Province.Dynamic then breathing heavily makes few expectorant at ordinary times, and sense is cold accidentally recently, and begin then slight fever aversion to cold, though mouth is drunk water yearningly and not, and clear urine in large amounts, more rale out of breath on the three, flushing as adornment, coma in silence, sweating Jin Jin, deadly cold hand and foot, the black profit of tongue fur, two cun, arteries and veins is slick and frivolous and carefully, two chis are suddenly enlightened and empty, blood 9.33/5.0kpa.Comprehensive analysis to both pulse condition and symptoms, intends examining: typhoid fever floating YANG disease.Give the embodiment of the present invention 1 drug administration, serve on 7 doses of healings.
Case 2
Gong so-and-so, man, 58 years old, people from Linquan County, Anhui Province.Went to a doctor on 07 20th, 2012.Tongue is black, thirsty few drink, coma in silence, Shou Zuliang, blood pressure 12.00/7.5kpa.Give the embodiment of the present invention 2 drug administration, serve on 3 doses of healings.
Case 3
Jiang, female, 58 years old, people from Taihe County, Anhui Province.Went to a doctor on 01 26th, 2012.Brothers are cool, mouthfeel sweet taste, uncomfortable in chest, flaccidity of the heart-yang, the dysfunction of the spleen.Give the embodiment of the present invention 1 drug administration, serve on 3 doses of healings.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.
Claims (2)
1. one kind is used for the treatment of the Chinese medicine composition of typhoid fever floating YANG disease, it is characterized in that, be made up of the crude drug of following weight: Bulbus Allii Fistulosi 90-110g, Radix Aconiti Lateralis Preparata 19-21g, Cortex Cinnamomi 9-11g, Rhizoma Zingiberis 9-11g, Radix Ginseng Rubra 9-11g, Fructus Schisandrae Chinensis 4-6g, Radix Ophiopogonis 9-11g, Fructus Jujubae 2-4 piece, Radix Astragali 19-21g, Os Draconis (calcined) 6-8g, Concha Ostreae (calcined) 7-9g, Poria 9-11g, Rhizoma Atractylodis Macrocephalae (parched) 9-11g, Rhizoma Pinelliae Preparatum 5-7g, Ramulus Cinnamomi 9-11g, Carapax et Plastrum Testudinis 14-16g, Carapax Trionycis 14-16g, Radix Paeoniae Alba 9-11g, Radix Rehmanniae Preparata 9-11g.
2. a kind of Chinese medicine composition being used for the treatment of typhoid fever floating YANG disease according to claim 1, it is characterized in that, be made up of the crude drug of following weight: Bulbus Allii Fistulosi 100g, Radix Aconiti Lateralis Preparata 20g, Cortex Cinnamomi 10g, Rhizoma Zingiberis 10g, Radix Ginseng Rubra 10g, Fructus Schisandrae Chinensis 5g, Radix Ophiopogonis 10g, 3 pieces, Fructus Jujubae, Radix Astragali 20g, Os Draconis (calcined) 7g, Concha Ostreae (calcined) 8g, Poria 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Rhizoma Pinelliae Preparatum 6g, Ramulus Cinnamomi 10g, Carapax et Plastrum Testudinis 15g, Carapax Trionycis 15g, Radix Paeoniae Alba 10g, Radix Rehmanniae Preparata 10g.
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