CN101670076B - Traditional Chinese medicine composition for treating disease of chronic nephritis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating disease of chronic nephritis and preparation method thereof Download PDF

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CN101670076B
CN101670076B CN2009103091317A CN200910309131A CN101670076B CN 101670076 B CN101670076 B CN 101670076B CN 2009103091317 A CN2009103091317 A CN 2009103091317A CN 200910309131 A CN200910309131 A CN 200910309131A CN 101670076 B CN101670076 B CN 101670076B
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radix
rhizoma
semen
fructus
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CN101670076A (en
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王峰
王文奎
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Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
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Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
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Abstract

The invention discloses a new traditional Chinese medicine composition for treating the disease of chronic nephritis and a preparation method thereof. The composition mainly comprises the following raw medicines: tuckahoe, notopterygium root, atractylodes macrocephala koidz, oriental waterplantain rhizome, plantain seed, rhizoma atractylodis, officinal magnolia bark, areca peel, rheum officinale, chrysanthemum, taraxacum officinale root, amur corktree bark, rhizoma cyperi, eucommia bark, zanthoxylum pipertum, talc, Japanese climbing fern spore, glossy privet fruit, epimedium herb, semen allii tuberose, angelica, pyrrosia lingua, akebiaquinata, medicated leaven, malt, gizzard pepsin, cape jasmine, immature bitter orange, pericarpium zanthoxyli, Chinese eaglewood, loosestrife, pollen typhae carbonisatus, cacumen biotae carbonisatus and semen euryales. The composition can be prepared into any one common oral preparation according to the conventional traditional Chinese medicine preparation method. The composition can obviously improve the symptoms such as abdominal fullness and distention, anasarca, fatigue and heaviness, chest stuffiness and poor appetite, aching and limp waist and knees, extreme chilliness, palpitation and severe palpitation and the like, and features confirmed clinical effects, obvious and quick effects. The composition basically combines the medicinal and editable medicines specified in the State Pharmacopoeia, thus having the advantages of low cost and no toxic side effects basically, etc.

Description

A kind of Chinese medicine composition for the treatment of disease of chronic nephritis and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of disease of chronic nephritis.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment disease of chronic nephritis of crude drug with the Chinese herbal medicine.
Background technology
At present, chronic nephritis has been come into our ten million family in a kind of popular sick mode, no matter be white collar, or the civilian has been subjected to the harm of chronic nephritis.The acute glomerulonephritis onset is failed thorough control, infection or reason such as overworked, all can bring out chronic nephritis.The chronic nephritis insidious onset, the course of disease is long, and as not controling effectively, the later stage can be developed into the multiple diseases that have a strong impact on Health and Living such as uremia, renal insufficiency so that renal failure, and the clinical onset rate has the trend of continuous rising in recent years.
Still the method for not having at present specific treatment chronic nephritis, doctor trained in Western medicine is with hormone, immunosuppressant treatment, repeatability and intensive side effect are arranged, that treats is lack of standardization, the harm of chronic nephritis is increased the weight of, complication is more and more, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines, treating both the principal and secondary aspects of a disease of Chinese traditional treatment chronic nephritis, deficiency and excess is also controlled, inside and outside logical the accent, emergency is taken in concurrently, filters out the natural plant of warming the kidney to promote diuresis, replenishing QI to invigorate the spleen, nourishing YIN for suppressing the hyperactive YANG, according to the theory of Chinese medical science prescription, be prepared from according to certain weight proportion.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment chronic nephritis that toxic and side effects is minimum is provided
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment disease of chronic nephritis of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of the disease of chronic nephritis disease of the present invention, the component of main following weight portion is formed:
Poria 1~50 gram, Rhizoma Et Radix Notopterygii 1~30 gram, Ramulus Cinnamomi 1~50 gram, the Rhizoma Atractylodis Macrocephalae 1~40 gram, Rhizoma Alismatis 1~30 gram, Semen Plantaginis 1~40 gram, Flos Lonicerae 1~40 gram, Pericarpium Citri Reticulatae 1~50 gram, Radix Curcumae 1~30 gram, Rhizoma Atractylodis 1~30 gram, Cortex Magnoliae Officinalis 1~30 gram, Pericarpium Arecae 1~50 gram, Radix Et Rhizoma Rhei 1~50 gram, Flos Chrysanthemi 1~30 gram, Herba Taraxaci 1~40 gram, Herba Violae 1~40 gram, Cortex Phellodendri 1~50 gram, Rhizoma Chuanxiong 1~30 gram, Rhizoma Cyperi 1~50 gram, the Cortex Eucommiae 1~40 gram, Radix Astragali 1~50 gram, Radix Codonopsis 1~30 gram, Radix Paeoniae Rubra 1~30 gram, the Radix Paeoniae Alba 1~50 gram, Rhizoma Dioscoreae 1~50 gram, Semen Coicis 1~30 gram, Fructus Zanthoxyli order 1~30 gram, Talcum 1~50 gram, Spora Lygodii 1~50 gram, Semen Persicae 1~20 gram, Flos Carthami 1~20 gram, Radix Stephaniae Tetrandrae 1~30 gram, Fructus Ligustri Lucidi 1~30 gram, Herba Epimedii 1~30 gram, Semen Allii Tuberosi 1~30 gram, Radix Angelicae Sinensis 1~50 gram.
Be preferably:
Poria 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Flos Chrysanthemi 10 grams, Herba Taraxaci 10 grams, Herba Violae 10 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Radix Paeoniae Rubra 10 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Dioscoreae 20 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
Rhizoma sparganic 1~30 gram, Rhizoma Curcumae 1~30 gram, Folium Pyrrosiae 1~40 gram, Caulis Akebiae 1~30 gram, Herba Dianthi 1~30 gram, Massa Medicata Fermentata 1~50 gram, Fructus Hordei Germinatus 1~30 gram, Endothelium Corneum Gigeriae Galli 1~30 Ke, Herba Polygoni Avicularis 1~40 gram, Fructus Gardeniae 1~40 gram, Fructus Aurantii Immaturus 1~50 gram, the Radix Aucklandiae 1~40 gram, Fructus Zanthoxyli 1~30 gram, Rhizoma Zingiberis 1~40 gram, Lignum Aquilariae Resinatum 1~20 gram, Fructus Lycii 1~30 gram, Herba Lysimachiae 1~30 gram, Pollen Typhae carbon 1~30 gram, Platycladi Cacumen carbonisatum 1~30 gram, Nodus Nelumbinis Rhizomatis 1~30 gram, Semen Euryales 1~40 gram.
Be preferably:
Rhizoma sparganic 10 grams, Rhizoma Curcumae 10 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 Ke, Herba Polygoni Avicularis 20 grams, Fructus Gardeniae 15 grams, Fructus Aurantii Immaturus 30 grams, the Radix Aucklandiae 20 grams, Fructus Zanthoxyli 10 grams, Rhizoma Zingiberis 15 grams, Lignum Aquilariae Resinatum 10 grams, Fructus Lycii 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 grams.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, the five internal organs differentiation of syndromes of YIN and YANG guiding principle is that Thailand one and Pu (Beijing) Chinese medicine academy president Mr. Wang Feng take the lead in proposing, once foundation, be subjected to the traditional Chinese medical science also older generation's great attention and appreciation immediately, and the problem that obtains the Ministry of Science and Technology's 973 plans is subsidized, launch further investigation, by a large amount of clinical case checking in nearly 16 years, and the academic discuss that reaches the several years, establish its status in the Chinese medical discrimination theory substantially, can be used as the guiding principle of all dialectical theories of Chinese medicine.
The five internal organs differentiation of syndromes of YIN and YANG is the comprehensive expression of of all dialectical theories of the traditional Chinese medical science such as eight steel are dialectical, the differentiation of qi-blood-body fluid, differentiation of febrile diseases in accordance with the theory of the six meridians, determining the pathogenesis of ZANG-FU disease based on the differentiation of symptoms and signs, differentiation of syndromes in seasonal febrile diseases according to four phases, differentiation of syndrome according to the pathgenesis of SAN JIAO, it is numerous just simple that Chinese medical discrimination is theorized, just with the dialectical thinking of filtering, clear and definite dialectical entity, real is the dialectical theory innovation achievement of Chinese medicine.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2~5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2~4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The treatment that the present invention is directed to the disease of chronic nephritis patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve renal function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: Poria 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 gram Herba Polygoni Avicularis 20 grams, Fructus Aurantii Immaturus 30 grams, Fructus Zanthoxyli 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 grams.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: Poria 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 gram Herba Polygoni Avicularis 20 grams, Fructus Aurantii Immaturus 30 grams, Fructus Zanthoxyli 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 grams.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material according to following weight portion: Poria 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 gram Herba Polygoni Avicularis 20 grams, Fructus Aurantii Immaturus 30 grams, Fructus Zanthoxyli 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 grams.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800~1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material according to following weight portion: Poria 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 gram Herba Polygoni Avicularis 20 grams, Fructus Aurantii Immaturus 30 grams, Fructus Zanthoxyli 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 grams.
Each raw material of above-mentioned weight is mixed, grind into cross 600~1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material according to following weight portion: Poria 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 gram Herba Polygoni Avicularis 20 grams, Fructus Aurantii Immaturus 30 grams, Fructus Zanthoxyli 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 grams.
Each raw material of above-mentioned weight is mixed, after decocting for three times, three filtrates is mixed, filter, be concentrated into the concentration of regulation, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
[experimental example] traditional Chinese medicine composition for treating disease of chronic nephritis of the present invention patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 132 routine patients altogether, wherein male 88 examples, women 44 examples; The oldest person 73 years old, the age reckling has only 16 years old.
Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2~5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2~4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 6 courses of treatment altogether.
The therapeutic evaluation standard
Cure: distension and fullness in the abdomen, hydrosarca, asthenia are stranded heavy, uncomfortable in chest indigestion and loss of appetite, soreness of the waist and knees, aversion to cold and cold limbs, severe palpitation.Sign is improved fully, and the patient does not have any bad sensation, and is happy, in high spirits.
Produce effects: distension and fullness in the abdomen, hydrosarca, asthenia are stranded heavy, uncomfortable in chest indigestion and loss of appetite, soreness of the waist and knees, aversion to cold and cold limbs, severe palpitation.Sign is significantly improved, and the patient does not have bad sensation substantially, and is happy, and spirit is fine.
Effectively: distension and fullness in the abdomen, hydrosarca, asthenia are stranded heavy, uncomfortable in chest indigestion and loss of appetite, soreness of the waist and knees, aversion to cold and cold limbs, severe palpitation.Sign obviously changes, and random thoughts have discomfort slightly, but can accept, and mood is better, and energy is more abundant.
Invalid: sign does not have any change, and symptom such as preceding feels depressed, and lethargy is depressed.
Model case:
1, multitude, woman, 24 years old, office worker.
Face's edema twice a few months ago, all do not treat and spontaneous regression.Last month, edema appearred in eyelid, head, gradually spread to whole body and be in hospital, doctor trained in Western medicine is examined and is the chronic nephritis acute attack, through using treatments such as hormone, diuretic, edema disappeared in 1 week, but albuminuria continues to engender hormone side effect (+++) to (++ ++), whole body telangiectasis and rubescent, long on the face acne, two temporos have pulsatile headache, and the clothes sleeping pill beginning can be fallen asleep but easily be waken up with a start easy excited excitation; Alopecia.Take Chinese medicine composition of the present invention after 1 month, symptom is greatly taken on a new look, and the urine egg significantly improves (+), takes Chinese medicine composition of the present invention again 3 months, and all symptoms all disappear.
2, Zhang, man, 50 years old, manager.
Be busy with one's work, overworked, occurred before three months with the albuminuria hematuria, the kidney puncture is shown: slight mesentery hypertrophy, twenty-four-hour urine albumen 1g/24 hour, white and thin fur is greasy, and matter is red partially, and arteries and veins is soft, adopts hormone therapy, and because of side effect is bigger, patient refuses to continue treatment.After taking 1 first quarter moon of Chinese medicine composition of the present invention, symptom is significantly alleviated, and takes Chinese medicine composition of the present invention again 3 months, and is all normal.
3, Tang, woman, 20 years old, student.
Know swollen half a year all over the body, amenorrhea simultaneously, puffiness of face, abdominal part has shifting dullness, the lower limb finger submerged while pressing, emaciated physique, the dim Huang of complexion, pulse condition is thin and delicate, urine protein (+++), the conditioning that once took traditional Chinese medicine is not seen to be clearly better.Take Chinese medicine composition of the present invention after 1 month, symptom is greatly taken on a new look, and continuous clothes Chinese medicine composition of the present invention was fully recovered in 2 months, and symptom all disappears.
4, Zhao, man, 48 years old, peasant.
The patient began to occur anasarca, oliguria before 2 years.Be diagnosed as " chronic nephritis " at certain county hospital, recur after curing half a year in hospital.Edema repeatedly takes place one year over.The appearance limbs are all swollen, lower limb more so, the depression of pressing, oliguria such as strong tea, abdominal distention and anorexia, complexion is dark dim, corpulent tongue has indentation greatly, tongue plain boiled water is sliding, deep-thready pulse.Take Chinese medicine composition of the present invention after 1 month, symptom is significantly improved, and continuous clothes Chinese medicine composition of the present invention is surplus February, the bimester after follow up a case by regular visits to and can participate in rural labor.Follow up a case by regular visits to not recurrence in 3 years.&
5, Wang, man, 63 years old, retired employees.
Be chronic nephritis at certain hospital diagnosis before 3 years, during the state of an illness often repeatedly, recur because of overworked in the recent period, a week comes, anasarca more very, urine drop difficulty goes out, abdominal part swells and the urgency that stretches tight, loss of appetite.Limb edema is not warm, and skin and face, words purple are dim.But mind is still clear, deep-thready pulse but not anxious number.Take Chinese medicine composition of the present invention after 3 days, the urine amount heightens, and edema has disappeared most, and spiritual amelioration was taken Chinese medicine composition of the present invention again 3 months, and is all normal.
6, the week certain, woman, 45 years old, teacher.
The patient suffered from nephritis before 5 years, repeatedly the outbreak, every outbreak once, the state of an illness increases the weight of once, body constitution descends once, this inferior to before three days because of the cholelithiasis grand mal brings out, fever, slight chill, breast flank distension and the pain, light red tongue is tender, tongue indented at the margin and tip, the white and moist cunning of tongue book, the dim purple of lip, CHI-pulse being weak, umbilicus week, wab board was hard, and the urine amount is lacked yellow skin, and stool is rushed down, urine examination albumen (++ ++), body temperature 38: 3 degree, 70~110 millimeters/mercury column of blood pressure.Take Chinese medicine composition of the present invention, that night, sleep was good, and body has warm sense, and diarrhoea is ended, and urine is increased, body temperature 36: 8 degree, and continuous clothes Chinese medicine composition of the present invention 3 months, all symptoms all disappear, and follow up a case by regular visits to not recurrence in 3 years.
7, poplar, man, 46 years old, workman.
Suffer from " chronic nephritis " 1 year surplus, local diagnosis and treatment are invalid comes to go to a doctor patient's puffiness of face, now float as the silkworm that crouches pale and dark complexion, the blue or green crow of lip, somnolence does not have god, and the look asthenia is to the utmost, and ascites expands in the abdomen, its shape such as gourd, edema of lower limbs is below the shin instep, that presses then caves in and difficult answering, and the heavy sensation of the body bed is difficult to change one's position, lower abdomen also weighs down to expand has a pain, and tastelessness is not thought food, oliguria.Examine its tongue arteries and veins, the light folder of color is blue or green though tongue moistens, and moist and slippery fur is and greyish black, and pulse condition is heavy unable late.Take Chinese medicine composition of the present invention after 15 days, symptom is greatly taken on a new look, the basic cancellation of edema, continuous clothes Chinese medicine composition of the present invention 3 months is normal, energetic fully.
Five, therapeutic outcome:
In the 132 routine cases of being accepted for medical treatment,, wherein cure 79 examples through treatment in 6 months, produce effects 28 examples, effective 22 examples, invalid 3 examples, total effective rate reaches 97%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment disease of chronic nephritis patient.

Claims (5)

1. Chinese medicinal capsule agent for the treatment of disease of chronic nephritis, it is characterized in that: take by weighing each raw material: Poria 30 grams by following weight portion, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 gram Herba Polygoni Avicularis 20 grams, Fructus Aurantii Immaturus 30 grams, Fructus Zanthoxyli 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 restrains, and grinds into after each component of above-mentioned weight is mixed to incapsulate promptly after fine powder is crossed 1500 mesh sieves.
2. Chinese medicine granules for the treatment of disease of chronic nephritis, it is characterized in that: take by weighing each raw material: Poria 30 grams by following weight portion, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 gram Herba Polygoni Avicularis 20 grams, Fructus Aurantii Immaturus 30 grams, Fructus Zanthoxyli 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 grams, each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
3. Chinese medicinal tablet for the treatment of disease of chronic nephritis, it is characterized in that: take by weighing each raw material: Poria 30 grams according to following weight portion, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 gram Herba Polygoni Avicularis 20 grams, Fructus Aurantii Immaturus 30 grams, Fructus Zanthoxyli 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 grams, each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800~1200 order dusting covers, make tablet promptly.
4. medicine pill for the treatment of disease of chronic nephritis, it is characterized in that: take by weighing each raw material: Poria 30 grams according to following weight portion, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 gram Herba Polygoni Avicularis 20 grams, Fructus Aurantii Immaturus 30 grams, Fructus Zanthoxyli 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 grams, each raw material of above-mentioned weight is mixed, grind into cross 600~1000 mesh sieves behind the fine powder after, make pill promptly.
5. Chinese medicine oral liquid for the treatment of disease of chronic nephritis, it is characterized in that: take by weighing each raw material: Poria 30 grams according to following weight portion, Rhizoma Et Radix Notopterygii 20 grams, Ramulus Cinnamomi 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Flos Lonicerae 10 grams, Pericarpium Citri Reticulatae 30 grams, Radix Curcumae 15 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Arecae 30 grams, Radix Et Rhizoma Rhei 30 grams, Cortex Phellodendri 30 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Cyperi 40 grams, the Cortex Eucommiae 20 grams, Radix Astragali 30 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Fructus Zanthoxyli order 15 grams, Talcum 30 grams, Spora Lygodii 30 grams, Semen Persicae 10 grams, Flos Carthami 10 grams, Radix Stephaniae Tetrandrae 10 grams, Fructus Ligustri Lucidi 20 grams, Herba Epimedii 20 grams, Semen Allii Tuberosi 10 grams, Radix Angelicae Sinensis 30 grams, Folium Pyrrosiae 20 grams, Caulis Akebiae 20 grams, Herba Dianthi 20 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 20 grams, Endothelium Corneum Gigeriae Galli 20 gram Herba Polygoni Avicularis 20 grams, Fructus Aurantii Immaturus 30 grams, Fructus Zanthoxyli 10 grams, Herba Lysimachiae 15 grams, Pollen Typhae carbon 10 grams, Platycladi Cacumen carbonisatum 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Semen Euryales 20 grams, each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into the concentration of regulation, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
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