CN103599297B

CN103599297B - A kind of medicament for the treatment of Qi deficiency blood stasis type cerebral infarction

Info

Publication number: CN103599297B
Application number: CN201310625978.2A
Authority: CN
Inventors: 赵吉凤
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-11-28
Filing date: 2013-11-28
Publication date: 2015-11-11
Anticipated expiration: 2033-11-28
Also published as: CN103599297A

Abstract

The present invention relates to a kind of medicament for the treatment of Qi deficiency blood stasis type cerebral infarction, it is made up by weight of following bulk drugs: Herba polygoni divaricati 8 parts, Fructus Gardeniae 9 parts, Radix Cochleariae officinalis grass 6 parts, 9 parts, Folium Nelumbinis, Herba Fimbristylis dichotomae 6 parts, Folium Artemisiae Argyi 7 parts, ligustrum sinense 5 parts, Radix Semiaquilegiae 3 parts, Herba Taraxaci 9 parts, Dendrophthoe pentandra (L.) Miq-Loranthus pcntandrus L. 2 parts, Cortex Cinnamomi 8 parts, Rhizoma begoniae pedatifidae 3 parts, stone maple medicine 6 parts, Fructus Lycii 7 parts, Herba Lanceae Tibeticae 2 parts and Herba Sonchi Arvensis 3 parts.Use natural drug in the medicament for the treatment of Qi deficiency blood stasis type cerebral infarction of the present invention, therefore it has instant effect, good effect, the advantage that has no side effect.

Description

A kind of medicament for the treatment of Qi deficiency blood stasis type cerebral infarction

Technical field

The present invention relates to field of medicaments, specifically, relate to a kind of medicament for the treatment of Qi deficiency blood stasis type cerebral infarction.

Background technology

Apoplexy is suddenly fainted, syncope, and the distortion of commissure that occurs together, dysphonia, hemiplegia are a class disease of cardinal symptom.This disease is divided into 2 types: cerebral infarction and hemorrhagic apoplexy.Cerebral infarction and the said cerebral infarction of modern medicine, due to cerebral atherosclerosis, blood vessel internal membrane damage makes cerebral arteries luminal stenosis, and then local thrombus is formed because of many factors, stricture of artery is increased the weight of or entirely shuts, cause brain tissue ischemia, anoxia, necrosis, cause a kind of cerebrovascular of delayed ischemic neurological deficits.Chinese medicine reduction blood viscosity, improve microcirculation, there is unique effect the aspects such as antiplatelet aggregation, to treatment and prevention of stroke significant.

Summary of the invention

The object of this invention is to provide a kind of medicament for the treatment of Qi deficiency blood stasis type cerebral infarction.

In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of Qi deficiency blood stasis type cerebral infarction, it is made up by weight of following bulk drugs: Herba polygoni divaricati 8 parts, Fructus Gardeniae 9 parts, Radix Cochleariae officinalis grass 6 parts, 9 parts, Folium Nelumbinis, Herba Fimbristylis dichotomae 6 parts, Folium Artemisiae Argyi 7 parts, ligustrum sinense 5 parts, Radix Semiaquilegiae 3 parts, Herba Taraxaci 9 parts, Dendrophthoe pentandra (L.) Miq-Loranthus pcntandrus L. 2 parts, Cortex Cinnamomi 8 parts, Rhizoma begoniae pedatifidae 3 parts, stone maple medicine 6 parts, Fructus Lycii 7 parts, Herba Lanceae Tibeticae 2 parts and Herba Sonchi Arvensis 3 parts.

Preferably, described medicament is tablet, dispersible tablet, rapidly dissolving tablet, decoction or granule.

In the present compositions, Herba polygoni divaricati, Fructus Gardeniae, Radix Cochleariae officinalis grass are monarch drug; Folium Nelumbinis, Herba Fimbristylis dichotomae, Folium Artemisiae Argyi, ligustrum sinense are ministerial drug; Radix Semiaquilegiae, Herba Taraxaci, Dendrophthoe pentandra (L.) Miq-Loranthus pcntandrus L., Cortex Cinnamomi, Rhizoma begoniae pedatifidae are adjuvant drug; Stone maple medicine, Fructus Lycii, Herba Lanceae Tibeticae and Herba Sonchi Arvensis for making medicine, various composition synergism, thus play optimum efficiency.

Use natural drug in the medicament for the treatment of Qi deficiency blood stasis type cerebral infarction of the present invention, therefore it has instant effect, good effect, the advantage that has no side effect.

Accompanying drawing explanation

With reference to " Chinese medicine voluminous dictionary " second edition, being described as follows of some crude drug used in the present invention:

Fig. 1 is the explanation of Herba polygoni divaricati;

Fig. 2 is the explanation of Radix Cochleariae officinalis grass;

Fig. 3 is the explanation of Herba Fimbristylis dichotomae;

Fig. 4 is the explanation of ligustrum sinense;

Fig. 5 is the explanation of Radix Semiaquilegiae;

Fig. 6 is the explanation of Dendrophthoe pentandra (L.) Miq-Loranthus pcntandrus L.;

Fig. 7 is the explanation of Rhizoma begoniae pedatifidae;

Fig. 8 is the explanation of stone maple medicine;

Fig. 9 is the explanation of Herba Lanceae Tibeticae;

Figure 10 is the explanation of Herba Sonchi Arvensis

Detailed description of the invention

Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.

The preparation of embodiment 1 decoction of the present invention

Get Herba polygoni divaricati 8 grams, Fructus Gardeniae 9 grams, Radix Cochleariae officinalis grass 6 grams, 9 grams, Folium Nelumbinis, Herba Fimbristylis dichotomae 6 grams, Folium Artemisiae Argyi 7 grams, ligustrum sinense 5 grams, Radix Semiaquilegiae 3 grams, Herba Taraxaci 9 grams, Dendrophthoe pentandra (L.) Miq-Loranthus pcntandrus L. 2 grams, Cortex Cinnamomi 8 grams, Rhizoma begoniae pedatifidae 3 grams, stone maple medicine 6 grams, Fructus Lycii 7 grams, Herba Lanceae Tibeticae 2 grams and Herba Sonchi Arvensis 3 grams, add 8000 milliliters, water, heat 5 hours under the condition of reflux.Filter, filtrate is decoction of the present invention.

Experimental example

Select dialectical genus Qi deficiency blood stasis type ischemic stroke patients 16 example.Case inclusive criteria: (1) is over the adult of 18 one full year of life; (2) meet the diagnostic criteria of cerebral infarction syndrome of blood stasis due to qi deficiency: acute onset, cardinal symptom be hemiplegia, speech is held high up puckery or in silence, white, the shortness of breath and fatigue of crooked mouth and tongue, hemianesthesia, complexion Guang, slobbering is from sweating, thin white fur of tongue or greasy, deep-thready pulse or stringy and thready pulse in vain; (3) patient of cerebral infarction is diagnosed as through CT or MRI; (4) without serious disturbance of consciousness when falling ill.Case exclusion standard: (1) tumor, fat, air or other mechanical plug person; Craniocerebral trauma history in (2) 1 months; Major operation or main organs biopsy history in (3) 2 weeks; (4) 3 weeks alimentary tract hemorrhage histories; (5) serious hepatic and renal function exception person; (6) platelet count is less than 10 × 10 ⁹/ L; (7) blood glucose is less than 2.7mmo1/L or is greater than 22.3mmol/L; (8) refusal regularly carry out the person of following up a case by regular visits to.

Use decoction obtained in embodiment 1 to treat, wherein one day 1 time, oral 200 milliliters at every turn, treating 90 days is a course for the treatment of.

During drug administration, detect that all Blood of Patients are conventional, urine is conventional, stool routine examination, hepatic and renal function, blood pressure and blood lipoid electrolyte, homocysteine, lectin from hemolymph, coagulation indexes, and timing check coherent detection index.Carry out before all patient treatments, after treatment 3d and after treatment 14d function of nervous system's condition grading (" clinical neurologic deficit of stroke patients degree standards of grading " with reference to Chinese Medical Association the 4th cerebrovascular academic conference is passed through) (Chinese Medical Association's the 4th cerebrovascular academic conference group in the whole nation. all kinds of cerebrovascular disease diagnosis main points [J]. Chinese Journal of Neurology, 1996,29 (6): 379-381.), before treatment and after treatment 90d, all patient's daily life active abilities are assessed, adopt Barthel index score method to mark.Measure the hemorheology of patient before and after treatment simultaneously, and content of homocysteine.

Follow up a case by regular visits to

Discharged patients regularly carries out follow-up, and follow up time was by November 1st, 2013.Follow up a case by regular visits to content to comprise and assessing daily life active ability, the situation of medication treatment, then vascular events of making up one's mind, and dead.

Statistical analysis

Adopt SPSS13.0 software building database and carry out statistical analysis.Measurement data adopts mean ± standard deviation to represent.The results are shown in following table.Refer to after treatment in following table that treatment is after 90 days.

Claims

1. treat the medicament of Qi deficiency blood stasis type cerebral infarction for one kind, it is characterized in that, it is made up by weight of following bulk drugs: Herba polygoni divaricati 8 parts, Fructus Gardeniae 9 parts, Radix Cochleariae officinalis grass 6 parts, 9 parts, Folium Nelumbinis, Herba Fimbristylis dichotomae 6 parts, Folium Artemisiae Argyi 7 parts, ligustrum sinense 5 parts, Radix Semiaquilegiae 3 parts, Herba Taraxaci 9 parts, Dendrophthoe pentandra (L.) Miq-Loranthus pcntandrus L. 2 parts, Cortex Cinnamomi 8 parts, Rhizoma begoniae pedatifidae 3 parts, stone maple medicine 6 parts, Fructus Lycii 7 parts, Herba Lanceae Tibeticae 2 parts and Herba Sonchi Arvensis 3 parts.