CN103599238B - A kind of Chinese medicine composition being used for the treatment of seborrheic alopecia - Google Patents
A kind of Chinese medicine composition being used for the treatment of seborrheic alopecia Download PDFInfo
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Abstract
A kind of Chinese medicine composition being used for the treatment of seborrheic alopecia, relate to field of Chinese herbal medicine technology, be made up of the crude drug of following weight: Cordyceps 4-6 gram, Cortex Dictamni 17-19 gram, Fructus Kochiae 11-13 gram, Radix Polygoni Multiflori 11-13 gram, Rhizoma Atractylodis 17-19 gram, Zaocys 17-19 gram, Radix Saposhnikoviae 11-13 gram, Radix Paeoniae Rubra 14-16 gram, Cortex Moutan 11-13 gram, Radix Rehmanniae 17-19 gram, Flos Sophorae 14-16 gram, Radix Angelicae Sinensis 14-16 gram, Bombyx Batryticatus 14-16 gram, Rhizoma Drynariae 14-16 gram, Cacumen Platycladi 11-13 gram, Flos Carthami 9-11 gram, Flos Caryophylli 14-16 gram.The present invention combines clinical practice for many years to develop on the basis of Traditional Chinese Medicine determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, has the high and feature such as to have no side effect of determined curative effect, instant effect, cure rate.
Description
Technical field
The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of Chinese medicine composition being used for the treatment of seborrheic alopecia.
Background technology
Along with social development, people more and more pay attention to self image, but alopecia becomes a kind of persistent ailment, perplexed a lot of people, wherein seborrheic alopecia is the one of alopecia, and seborrheic alopecia claimed male pattern alopecia in the past, male pattern alopecia, male alopecia, diffusivity alopecia, universality alopecia etc., it is sick and hereditary, androgen, seborrhea is correlated with, and common medication is as seborrhea health.Symptom is that scalp portion fat secretion is too much, and hair has greasy feeling.Clinical manifestation is the excessive spilling of patient's scalp fat, causes the greasy humidity of scalp, adds that dust and scurf mix, and within several days, does not wash hair just very dirty, and gives an offensive smell, especially all the more so when temperature height; Sometimes also to scratch where it itches inflammation with scalp, mainly because scalp is moist, the numerous raw infection of antibacterial causes seborrheic dermatitis.Alopecia is general first from the middle of two frontal eminences, forehead and the crown, then fill the air in the whole crown, but the hair of head surrounding less falls.Serious symptom person alopecia district becomes glossy shinny, and remaining hair becomes soft withered and yellow.
In prior art, the treatment of seborrheic alopecia is divided into oral medicine, medicine for external use and dietetic therapy.The clinical application effect of these medicines and prescription is all undesirable, function singleness, cannot reach the effect for the treatment of seborrheic alopecia.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of effective, the safe and reliable Chinese medicine composition being used for the treatment of seborrheic alopecia.
Technical problem to be solved by this invention realizes by the following technical solutions:
Be used for the treatment of a Chinese medicine composition for seborrheic alopecia, be made up of the crude drug of following weight,
Cordyceps 4-6 gram, Cortex Dictamni 17-19 gram, Fructus Kochiae 11-13 gram, Radix Polygoni Multiflori 11-13 gram, Rhizoma Atractylodis 17-19 gram, Zaocys 17-19 gram, Radix Saposhnikoviae 11-13 gram, Radix Paeoniae Rubra 14-16 gram, Cortex Moutan 11-13 gram, Radix Rehmanniae 17-19 gram, Flos Sophorae 14-16 gram, Radix Angelicae Sinensis 14-16 gram, Bombyx Batryticatus 14-16 gram, Rhizoma Drynariae 14-16 gram, Cacumen Platycladi 11-13 gram, Flos Carthami 9-11 gram, Flos Caryophylli 14-16 gram.
Preferred weight part of each crude drug is:
Cordyceps 5 grams, Cortex Dictamni 18 grams, the Fructus Kochiae 12 grams, Radix Polygoni Multiflori 12 grams, Rhizoma Atractylodis 18 grams, Zaocys 18 grams, Radix Saposhnikoviae 12 grams, Radix Paeoniae Rubra 15 grams, Cortex Moutan 12 grams, 18 grams, the Radix Rehmanniae, 15 grams, Flos Sophorae, Radix Angelicae Sinensis 15 grams, Bombyx Batryticatus 15 grams, Rhizoma Drynariae 15 grams, Cacumen Platycladi 12 grams, 10 grams, Flos Carthami, Flos Caryophylli 15 grams.
Crude drug used by the present invention can be bought from common Chinese shop and obtain, and its specification meets national Chinese crude drug standard.
Another object of the present invention is to provide a kind of method preparing the present composition, comprises the steps,
1) each taste crude drug is taken by weight described in prescription;
2) by above-mentioned each taste crude drug pulverization, incapsulate.
1, pharmacology analysis:
Cordyceps: tonifying deficiency, beneficial vital essence, relieving cough and resolving phlegm.
Cortex Dictamni: dispel the wind, dampness, heat clearing away, removing toxic substances.Control wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.
The Fructus Kochiae: " beautiful Chinese catalpa medicine solution ": treat the head and swell and ache, inguinal hernia the moon is ruined, pain in the lumbar region hypochondriac pain, dysentery, malignant boil.
Radix Polygoni Multiflori: " Kaibao Bencao ": main scrofula, subduing inflammation, treats women's head-ornaments wind skin ulcer, five hemorrhoid, only pained, beneficial vim and vigour, black moustache temples, improving healthy complexion.
Rhizoma Atractylodis: spleen invigorating, dampness, resolving depression, wards off dirty.
Zaocys: wind-damp dispelling, the meridian dredging." property of medicine opinion ": control pyretic toxicity wind, the raw skin ulcer of skin, eyebrow must come off, and Guo itches scabies etc.
Radix Saposhnikoviae: deliver, dispels the wind, and victory is wet, pain relieving.
Radix Paeoniae Rubra: clots absorbing, pain relieving, removing heat from blood, detumescence.
Cortex Moutan: clearing away heat and cooling blood, and blood repercussive.Control the pathogenic heat attacking blood system in febrile diseases, send out speckle, infantile convulsion, tells, is defeated in battle, has blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer, traumatic injury.
The Radix Rehmanniae: YIN nourishing, nourishes blood.
Flos Sophorae: heat clearing away, removing heat from blood, hemostasis.Control discharging fresh blood stool, hemorrhoidal bleeding, hematuria, stranguria with blood, metrorrhagia, epistaxis, under dysentery with red and white feces, wind heat conjunctival congestion, skin sore.
Radix Angelicae Sinensis: benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.
Bombyx Batryticatus: expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Control apoplectic aphasia, infantile convulsion, wind syndrome of head, acute throat trouble, sore throat, scrofula tuberculosis, wind skin ulcer urticaria, erysipelas, mastitis.
Rhizoma Drynariae: the kidney invigorating, invigorates blood circulation, hemostasis.Control suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus.
Cacumen Platycladi: removing heat from blood, hemostasis, wind-damp dispelling, loose toxic swelling.
Flos Carthami: " detailed outline ": invigorate blood circulation, moisturizes, pain relieving, loose swollen, stimulates the menstrual flow.
Flos Caryophylli: " Haiyao Bencao, Oversea Materia Medica ": main air infantile malnutrition is hidden, bone groove labor is smelly.Control gas, black moustache is sent out, parasite killing, treats five hemorrhoid, wards off evil and uncharms.
2, usage and consumption:
The dosage of medicine of the present invention depends on concrete dosage form, and the factor such as the age of patient, body weight, health status.
Instruction: each 6, every day 3 times, the morning, noon and afternoon take, and a course for the treatment of is 1 month.
3, the present composition has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and disease therapy, drops into the use link of disease therapy provide science and objective foundation to this medicine.
Its test method and result of the test are distinguished as follows:
1) animal acute toxicity test is carried out to capsule prepared by the present invention:
Medicine: the crude drug used by the present invention is bought from common Chinese shop and obtained, and its specification meets national Chinese crude drug standard.
Experimental animal: white mice, body weight is at about 50g, and male and female Stochastic choice, is bought by market.
Method and result: get white mice 30, hungry 20 hours, feeding 50g by filling with several times every every day, feeding one week continuously, observing 10 days, and mice is movable normal, non-toxic reaction, without dead.Show that oral liquid is without acute toxicity, clinical medicine dose safety.
2) long-term toxicity test for animals is carried out to capsule prepared by the present invention:
Experimental animal: rat, body weight is at 120-130g, and male and female Stochastic choice, is bought by market.
Method and result: get rat 20, be divided into 2 groups, often organize 10, wherein the 1st group as administration group, 40-50g is fed by filling with several times every every day, 2nd group of diet as a control group, once a day, continuous irrigation is fed 90 days, survey body weight, 24 hours sacrificed by decapitation after last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the change of tissues observed form, observe the effect of dosage, observe diet, movable change, experiment proves that administration group compares without significant change with matched group, equal non-toxic reaction, a kind of safe drugs.
4, diagnostic criteria
1) tcm diagnosis: be as the criterion with reference to People's Health Publisher's high medical president's state-compiled textbook " Surgery of Chinese Medicine " seborrheic alopecia diagnostic criteria.
2) in order to verify clinical efficacy, this prescription is tried out in Jieshou City, Anhui Province institute of traditional Chinese medicine, and random selecting is 50 routine patients wherein.
3) Therapeutic Method: take capsule of the present invention, divides for each person every day and takes for 3 times, one time 6, take 3 months continuously.
4) efficacy determination:
Cure: hair stops coming off, and alopecia all grows, and natural on-off cycles of hair growth density is normal, and hair quality thickness is normal;
Effective: hair stops coming off, and hair regeneration reaches more than 70%, and hair comparatively before increases thick but still sparse, hair quality jewelry, expensive clothing and other valuables;
Effective: alopecia stops, and hair regeneration reaches more than 20%;
Invalid: hair replacement is less than 10% or continue to come off, alopecia area is comparatively front to be expanded.
Concrete therapeutic outcome is see table 1;
Table 1
| Number of cases | Cure | Effective | Effectively | Invalid | Effective percentage (%) |
| 50 | 10 | 18 | 20 | 2 | 96 |
5, points for attention:
1. diet should be light, gives up alcohol and pungent, raw and cold, greasy food.
2. child, women breast-feeding their children, elderly and infirm should take under doctor instructs.
3. driver, work high above the ground person are cautious use of.
4. strictly take by usage and dosage.
5. pair this medicine and alcohol intolerance person forbidding, allergic constitution person be cautious use of.
6. prohibit the use when this property of drug changes.
7. please this medicine is placed on the place that child can not contact.
8. as used other medicines, please Ref Dr or pharmacist before using this medicine.
The invention has the beneficial effects as follows: the present invention combines clinical practice for many years to develop on the basis of Traditional Chinese Medicine determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs that there is the high and feature such as to have no side effect of determined curative effect, instant effect, cure rate.
Detailed description of the invention
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
Each crude drug is taken: Cordyceps 5 grams, Cortex Dictamni 18 grams, the Fructus Kochiae 12 grams, Radix Polygoni Multiflori 12 grams, Rhizoma Atractylodis 18 grams, Zaocys 18 grams, Radix Saposhnikoviae 12 grams, Radix Paeoniae Rubra 15 grams, Cortex Moutan 12 grams, 18 grams, the Radix Rehmanniae, 15 grams, Flos Sophorae, Radix Angelicae Sinensis 15 grams, Bombyx Batryticatus 15 grams, Rhizoma Drynariae 15 grams, Cacumen Platycladi 12 grams, 10 grams, Flos Carthami, Flos Caryophylli 15 grams by following weight.By above-mentioned each taste crude drug pulverization, be prepared into capsule according to a conventional method.
Embodiment 2
Each crude drug is taken: Cordyceps 6 grams, Cortex Dictamni 19 grams, the Fructus Kochiae 13 grams, Radix Polygoni Multiflori 13 grams, Rhizoma Atractylodis 19 grams, Zaocys 19 grams, Radix Saposhnikoviae 13 grams, Radix Paeoniae Rubra 16 grams, Cortex Moutan 13 grams, 19 grams, the Radix Rehmanniae, 16 grams, Flos Sophorae, Radix Angelicae Sinensis 16 grams, Bombyx Batryticatus 16 grams, Rhizoma Drynariae 16 grams, Cacumen Platycladi 13 grams, 11 grams, Flos Carthami, Flos Caryophylli 16 grams by following weight.By above-mentioned each taste crude drug pulverization, be prepared into capsule according to a conventional method.
Embodiment 3
Each crude drug is taken: Cordyceps 4 grams, Cortex Dictamni 17 grams, the Fructus Kochiae 11 grams, Radix Polygoni Multiflori 11 grams, Rhizoma Atractylodis 17 grams, Zaocys 17 grams, Radix Saposhnikoviae 11 grams, Radix Paeoniae Rubra 14 grams, Cortex Moutan 11 grams, 17 grams, the Radix Rehmanniae, 14 grams, Flos Sophorae, Radix Angelicae Sinensis 14 grams, Bombyx Batryticatus 14 grams, Rhizoma Drynariae 14 grams, Cacumen Platycladi 11 grams, 9 grams, Flos Carthami, Flos Caryophylli 14 grams by following weight.By above-mentioned each taste crude drug pulverization, be prepared into capsule according to a conventional method.
Model case:
Case 1
Section so-and-so, man, 48 years old, Dai Qiao people from town, Jieshou City, Anhui Province.Patient repeatedly occur over 3 years scalp overflow fat companion alopecia, develop into alopecia 60%, multiple therapy methods, all without effective.Take Chinese medicinal capsule of the present invention after 3 months, scalp recovers normal, no longer fuel-displaced, and horny layer recovers as usual, all over raw tiny hair.After continue again to have taken 3 months, natural on-off cycles of hair growth density is normal, recovers as ordinary person.
Case 2
Fourth so-and-so, man, 52 years old, people from market town, Singapore and Malaysia, Jieshou City, Anhui Province.Readme time medical: come off 3 years, dandruff is many, scalp pruritus, irritable, stays up late at ordinary times many, stress is large, red tongue with yellow fur.Examine as seborrheic alopecia.Take Chinese medicinal capsule of the present invention after 3 months, alopecia stops, and hair regeneration reaches more than 30%; Continue to take 3 months, patient grows not only black not only thick but also dense hair.
Case 3
Summer so-and-so, man, 36 years old, Anhui Province Fuyang City people.Suffer from seborrheic alopecia to have a surplus for 2 years, the satisfaction not to the utmost of western medicine effect.Rise in August, 2012 and use this Drug therapy, 3 greasy situations of the back haze wax course for the treatment of obviously alleviate, and have new sending out to grow, and after 6 courses for the treatment of, each alopecia position all has new sending out to grow.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.
Claims (2)
1. one kind is used for the treatment of the Chinese medicine composition of seborrheic alopecia, it is characterized in that, be made up of the crude drug of following weight: Cordyceps 4-6 gram, Cortex Dictamni 17-19 gram, Fructus Kochiae 11-13 gram, Radix Polygoni Multiflori 11-13 gram, Rhizoma Atractylodis 17-19 gram, Zaocys 17-19 gram, Radix Saposhnikoviae 11-13 gram, Radix Paeoniae Rubra 14-16 gram, Cortex Moutan 11-13 gram, Radix Rehmanniae 17-19 gram, Flos Sophorae 14-16 gram, Radix Angelicae Sinensis 14-16 gram, Bombyx Batryticatus 14-16 gram, Rhizoma Drynariae 14-16 gram, Cacumen Platycladi 11-13 gram, Flos Carthami 9-11 gram, Flos Caryophylli 14-16 gram; During preparation, by above-mentioned each taste crude drug pulverization, incapsulate.
2. a kind of Chinese medicine composition being used for the treatment of seborrheic alopecia according to claim 1, it is characterized in that, be made up of the crude drug of following weight: Cordyceps 5 grams, Cortex Dictamni 18 grams, the Fructus Kochiae 12 grams, Radix Polygoni Multiflori 12 grams, Rhizoma Atractylodis 18 grams, Zaocys 18 grams, Radix Saposhnikoviae 12 grams, Radix Paeoniae Rubra 15 grams, Cortex Moutan 12 grams, 18 grams, the Radix Rehmanniae, 15 grams, Flos Sophorae, Radix Angelicae Sinensis 15 grams, Bombyx Batryticatus 15 grams, Rhizoma Drynariae 15 grams, Cacumen Platycladi 12 grams, 10 grams, Flos Carthami, Flos Caryophylli 15 grams; During preparation, by above-mentioned each taste crude drug pulverization, incapsulate.
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| CN104398670B (en) * | 2014-12-09 | 2018-05-01 | 兰州古驰生物科技有限公司 | By clearing lung-heat heat except the Chinese medicine preparation of lung poison treatment alopecia seborrheica |
| CN104857110A (en) * | 2015-04-24 | 2015-08-26 | 孙玉 | Radix polygoni multiflori hair growing cream |
| CN106177851A (en) * | 2016-08-17 | 2016-12-07 | 马洪星 | A kind of Chinese medicine treating seborrheic alopecia |
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