CN103585650B - A kind of low temperature plasma endoscope sterilizing device and method - Google Patents
A kind of low temperature plasma endoscope sterilizing device and method Download PDFInfo
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- CN103585650B CN103585650B CN201310287335.1A CN201310287335A CN103585650B CN 103585650 B CN103585650 B CN 103585650B CN 201310287335 A CN201310287335 A CN 201310287335A CN 103585650 B CN103585650 B CN 103585650B
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- 238000000034 method Methods 0.000 title claims abstract description 39
- 230000001954 sterilising effect Effects 0.000 title claims abstract description 18
- 230000005495 cold plasma Effects 0.000 claims abstract description 16
- 230000005284 excitation Effects 0.000 claims abstract description 13
- 230000004936 stimulating effect Effects 0.000 claims abstract description 10
- 239000003595 mist Substances 0.000 claims abstract description 4
- 239000007789 gas Substances 0.000 claims description 50
- 238000004659 sterilization and disinfection Methods 0.000 claims description 24
- 238000001839 endoscopy Methods 0.000 claims description 15
- 239000002245 particle Substances 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 8
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 4
- 229910052734 helium Inorganic materials 0.000 claims description 4
- 239000001301 oxygen Substances 0.000 claims description 4
- 229910052760 oxygen Inorganic materials 0.000 claims description 4
- 239000007921 spray Substances 0.000 claims description 4
- 229910052786 argon Inorganic materials 0.000 claims description 3
- 230000000249 desinfective effect Effects 0.000 abstract description 5
- 239000002019 doping agent Substances 0.000 abstract 1
- 230000008569 process Effects 0.000 description 17
- 239000000463 material Substances 0.000 description 9
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 239000004810 polytetrafluoroethylene Substances 0.000 description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 3
- 206010011409 Cross infection Diseases 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- 206010029803 Nosocomial infection Diseases 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- FFBHFFJDDLITSX-UHFFFAOYSA-N benzyl N-[2-hydroxy-4-(3-oxomorpholin-4-yl)phenyl]carbamate Chemical compound OC1=C(NC(=O)OCC2=CC=CC=C2)C=CC(=C1)N1CCOCC1=O FFBHFFJDDLITSX-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000009849 deactivation Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 238000002324 minimally invasive surgery Methods 0.000 description 1
- 229910052754 neon Inorganic materials 0.000 description 1
- 229910052756 noble gas Inorganic materials 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 239000012495 reaction gas Substances 0.000 description 1
- 230000011218 segmentation Effects 0.000 description 1
- 238000010183 spectrum analysis Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000002341 toxic gas Substances 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
Abstract
The present invention relates to a kind of low temperature plasma endoscope sterilizing device and method, this device comprises Gas Control Module, power supply stimulating module, plasma generation module, Gas Control Module controls rare gas and strong active dopant gas by flow controller, realizes gas mixing ratio and flow velocity is adjustable; Power supply stimulating module utilizes sinusoidal or pulsed high voltage generator, for described plasma generation module provides stable excitation; Plasma generation module, by the electrode structure of overlap span, utilizes the mist based on rare gas to produce atmosphere cold plasma jet.This device can under atmospheric pressure produce length at 1cm to 2m, and diameter is in 0.2mm to 10mm scope, and even, stable, room temperature, strong active plasma jet, be applicable to disinfecting of different size endoscope.
Description
Technical field
The present invention relates to plasma disinfection field, particularly a kind of low temperature plasma endoscope sterilizing device based on overlap span electrode structure and method.
Background technology
Along with the progress of science and technology and people are to the raising day by day of health requirements, the application of endoscope is more and more extensive.Not only use in a large number in Minimally Invasive Surgery, and started to the development of routine physical examination field, global endoscope has broken through 10,000,000,000 dollars in 2010 in market, and the consumption can predicting endoscope will increase substantially.In order to adapt to the objective requirement of application development, the cross infection risk avoided nonrecoverable high cost Yu repeatedly use, studies efficient, safe, inexpensive, easy to operate endoscopy disinfection technology extremely urgent.
Because endoscope's price comparison is expensive and belong to not wet-heat resisting equipment, its sterilizing methods all are limited, strongly limit carrying out of clinical practice.The method being comparatively widely used in endoscopy disinfection now has hydrogen peroxide method, ethylene oxide sterilizing method, autoclaving etc.Autoclaving has been proved it cannot carry out effective deactivation to fraction of pathogens body.Hydrogen peroxide and oxirane belong to toxic gas, and these two kinds of methods adopt vacuum cavity, and apparatus expensive, usage are complicated, the processing time is long.In view of current effect, said method is still limited to the kill capability of fraction of pathogens body, there is the risk of cross infection, and there is hazard residue and can be damaged to endoscope's material.
Therefore, the sterilizing of endoscope's internal elongate pipeline is a more difficult task.Plasma can produce electric field, electric current, UV irradiation and various charged particle, free radical isoreactivity particle, can make pathogen downright bad or apoptosis fast.But, the method for current applied low pressure plasma, and low pressure plasma and H
2o
2there are 2 major defects in the method combined: (1) low air pressure condition needs vacuum chamber, and cost is high, operation inconvenience; (2) internal diameter of endoscope is at the mm order of magnitude, be even less than 1mm, and the electron mean free path of low pressure plasma is greater than 1cm, and this makes the difficulty producing high-density plasma very large, and plasma sterilization effect does not reach requirement.
In sum, prior art cannot under atmospheric pressure produce a kind of cover whole endoscope inwall, evenly, the plasma of stable, room temperature, need a kind of new sterilization method and plasma producing apparatus.
Summary of the invention
For solving the problems of the technologies described above, the invention discloses a kind of low temperature plasma endoscope sterilizing device, described device comprises Gas Control Module, power supply stimulating module, plasma generation module, it is characterized in that:
Described Gas Control Module controls composition proportion and the flow velocity of multiple reacting gas by multiple flow controller;
Described power supply stimulating module by high voltage power supply for described plasma generation module provides excitation;
Described plasma generation module, by the electrode structure of overlap span, produces length at 1cm to 2m, diameter at the atmosphere cold plasma jet of 0.2mm to 10mm.
Meanwhile, the invention also discloses a kind of method of low temperature plasma endoscopy disinfection, it is characterized in that:
Step 1, controls composition proportion and the flow velocity of multiple reacting gas by the multiple flow controllers in Gas Control Module;
Step 2, by high voltage power supply for described plasma generation module provides excitation;
Step 3, plasma generation module, by the electrode structure of overlap span, produces length at 1cm to 2m, diameter at the atmosphere cold plasma jet of 0.2mm to 10mm, for endoscopy disinfection.
Wherein, obtain atmosphere cold plasma by the mode of jet, the endoscopy disinfection process of different bore can be adapted to;
Wherein, by being produce electric discharge in main mist at rare gas, active particle kind and quantity in plasma is enhanced;
Wherein, utilize the electrode structure of overlap span, reduce discharge voltage and plasma temperature, be applicable to disinfecting of different length endoscope.
Wherein, the highfield produced by cold-plasma jet, UV, a large amount of active particles etc., realized the sterilization of endoscope inner surface, disinfect.
Accompanying drawing explanation
Fig. 1 is the structural representation of the endoscope sterilizing device in the present invention.
Fig. 2 is the structural representation of overlap span electrode in the present invention.Wherein: 21 is reacting gas, 22 is plasma jet tailer, and 23 is high-field electrode, and 24 is ground electrode.
Fig. 3 is the structural representation of single electrode in the present invention.A is quick assembly and disassembly type electrode, and wherein, 31 is support metal bar, is connected with high-field electrode or ground electrode bus; 32 is the metal draw-in groove of a side opening, and 32 and 31 by being weldingly connected.B is spring screw fixed pattern electrode, and wherein, 33 is main electrode, and 34 is auxiliary electrode, and 35 is nut, and 36 is screw, and 37 is repulsion spring; Main electrode is connected with high-field electrode or ground electrode bus, and auxiliary electrode is fixed by spring screw and main electrode, and realizes electrical connection.
Fig. 4 is the SEM result of the decontaminating apparatus endoscope material processed in the present invention, and 1. in this figure is before process, 2. for after process.
Detailed description of the invention
As shown in Figure 1, low temperature plasma endoscope sterilizing device comprises Gas Control Module, power supply stimulating module, plasma generation module, and Gas Control Module controls composition proportion and the flow velocity of multiple reacting gas by multiple flow controller; Power supply stimulating module by high voltage power supply for described plasma generation module provides excitation; Plasma generation module, by the electrode structure of overlap span, produces length at 1cm to 2m, diameter at the atmosphere cold plasma jet of 0.2mm to 10mm.
Composition graphs 1, the present invention: the problem first solving decontaminating apparatus reacting gas, achieves the mixing of differential responses gas; Secondly owing to have employed the electrode structure of overlap span, can adapt to the needs of different length endoscopy disinfection process, the length range of medical endoscope pipeline is between 1cm-2m; Again, present invention employs plasma jet structure, can adapt to the needs of different bore endoscopy disinfection process, medical endoscope internal diameter of the pipeline scope is between 0.2mm-10mm.So, hybrid reaction gas through jet pipeline, and under sine power supply excitation, produces atmosphere cold plasma jet, can adapt to different length, the disinfecting of different bore endoscope.
More excellent, in another embodiment: described flow controller is according to the flow of the different adjustment reacting gas of endoscope tube internal diameter.With regard to this embodiment, in order to ensure that the flow velocity of gas keeps within the specific limits, gas flow will increase along with the increase of endoscope tube internal diameter.The flow velocity of reacting gas is generally no more than 20m/s, because easily form turbulent flow after exceeding this value, makes plasma disinfection process uneven, also can affect the stability of electric discharge simultaneously.
More excellent, in another embodiment: described reacting gas with rare gas such as He, Ar for main discharge gas.With regard to this embodiment, rare gas makes plasma keep low temperature state, discharge temp, and discharge voltage reduces.So, decrease the damage of plasma endoscope inner surface material, simultaneously because noble gas discharge voltage is low, make it can not produce electric discharge at endoscope's outer wall.
More excellent, the strong active gases such as the air that can adulterate in rare gas, or adopt the rare gas (air plankton containing being no less than 0.1%) of low-purity, increase active particle kind and the quantity of electric discharge generation.
Further, the strong active gases of doping can be N equally
2, O
2, H
2the single components such as O, total doping proportioning is no more than 10%, and too high doping content can reduce Uniform discharge, promotes discharge voltage, increases gas temperature, is unfavorable for endoscopy disinfection process.
Further, under pulse excitation, discharge gas can be the strong active gases that air (containing humid air), oxygen etc. are cheap.
More excellent, in another embodiment, the described high voltage power supply for low temperature plasma excitation is sinusoidal high voltage power supply, and frequency is not higher than 100MHz.With regard to this embodiment, in practical application, the endoscope of process different length and caliber needs different voltage, the range of choice of sinusoidal high-voltage power voltage peak-to-peak value is at 3kV-50kV, the selection of frequency range is at 1kHz-100MHz, underfrequency is discharge instability then, and frequency is too high, and plasma fever phenomenon can be caused obvious.
More excellent, in another embodiment: described power supply stimulating module available pulse high voltage power supply replaces sinusoidal high voltage power supply, and its pulse frequency is between 50Hz-100MHz.The frequency of pulsed high voltage generator is higher, and the processing speed of plasma disinfection system is faster, and discharge voltage is lower, but plasma temperature can raise with frequency.With regard to this embodiment, under pulsed high-voltage source forcing, the formation efficiency of active particle is higher, simultaneously owing to reducing total discharge power, plasma temperature is reduced further.
More excellent, as shown in Figure 2, the electrode structure of described overlap span is alternately arranged by high-field electrode and ground electrode and realizes.Which employs same power supply to power, endoscope is then through the electrode be alternately arranged, and the endoscope inside between each adjacent high-field electrode and ground electrode can produce plasma, due to the multistage distribution of electrode assembly, can effectively reduce electric discharge required voltage.Further, according to the needs of different length endoscopy disinfection process, Ke Yizeng, pay less for electrode logarithm, even, the stable atmospheric pressure plasma that length does not wait can be produced like this, realize endoscope's inside sterilization fast by plasma.Parenthetically, even if there is uneven texture endoscope inside, does not also affect and disinfect effect, this is by plasma inherently characteristic decision.
More excellent, as shown in Figure 3: the structure of single electrode has quick assembly and disassembly type and spring screw fixed pattern two kinds.Quick assembly and disassembly type electrode be a kind of can the structure of quick-detachment, metal draw-in groove 32 is made up of elastic sheet metal, elasticity is good, be applicable to disinfecting of various outer diameter endoscope, spring screw fixed pattern electrode utilizes spring screw fixed endoscope pipeline, is suitable for various outer diameter endoscope equally by adjustment screw.All 3cm is being no more than, to obtain stable electric discharge and to ensure the uniformity that pipe interior is disinfected along the electrode width in endoscope channel direction and electrode gap.
More excellent, what described plasma generation module produced is plasma jet.Plasma jet reduce further discharge voltage and plasma temperature.Parenthetically, because the bur that jet itself is conducive to endoscope's inwall comes off, so fluidic architecture serves certain cleaning action simultaneously.
More excellent, described plasma jet structure, with spray point, reduces starting voltage.The existence of spray point reduces electric discharge initial conditions, and electric discharge is more easily realized.In practical application, at the high-field electrode place of endoscope one end, spray point is utilized to be incorporated into by high-pressure stage in electric discharge pipeline.So, electric discharge still belongs to dielectric barrier discharge category, only reduces discharge inception voltage by needle-tip corona.
In experiment, inventor utilizes the bacterium liquid containing E.coli antibacterial to pollute endoscope, then utilizes described plasma jet process 1 minute.After process, continue cultivation 24 hours by after the dilution of bacterium liquid, the last matched group paired observation bactericidal effect with not carrying out plasma jet process.Find, in the culture dish of the not diluted of plasma jet process, to have 10 at least in this embodiment
5individual E-coli bacterium colony reduces.As long as process 10s just can kill all E.coli antibacterials completely.Found by spectrum analysis, in the mixed gas discharge plasma of helium and oxygen, its O, OH isoreactivity particle produced is the crucial particle of sterilization.
More excellent, the cold-plasma jet that described overlap span electrode structure produces can not destroy endoscope's material.Endoscope's inner-wall material is PTFE material or other macromolecular material.Electron scanning result shown in composition graphs 4, with regard to this embodiment, in practical application, utilize described cold plasma process PTFE material 100 times, each processing time is 6 minutes.With regard to this embodiment, according to scanning electron microscopic observation result, find that PTFE material surface is not significantly damaged.
Meanwhile, the invention also discloses a kind of method of low temperature plasma endoscopy disinfection, it is characterized in that:
Step 1, controls composition proportion and the flow velocity of multiple reacting gas by the multiple flow controllers in Gas Control Module;
Step 2, by high voltage power supply for described plasma generation module provides excitation;
Step 3, plasma generation module, by the electrode structure of overlap span, produces length at 1cm to 2m, diameter at the atmosphere cold plasma jet of 0.2mm to 10mm, for endoscopy disinfection.
Wherein, obtain atmosphere cold plasma by the mode of jet, the endoscopy disinfection process of different bore can be adapted to;
Wherein, by being produce electric discharge in main mist at rare gas, active particle kind and quantity in plasma is enhanced;
Wherein, utilize the electrode structure of overlap span, reduce discharge voltage and plasma temperature, be applicable to disinfecting of different length endoscope.
Wherein, the highfield produced by cold-plasma jet, UV, a large amount of active particles etc., realized the sterilization of endoscope inner surface, disinfect.
With regard to above-described embodiment, it belongs to the embodiment of the method corresponding with foregoing first embodiment of the present invention.
In sum, endoscope sterilizing device of the present invention and method thereof have the following advantages: (1) the present invention proposes a kind of plasma electrically electrode structure of brand-new overlap span, this electrode structure is alternately arranged by high-field electrode and ground electrode, as long as meet the discharging condition between each adjacent electrode, just can produce plasma in the electrode gap of segmentation, and the cold plasma of different length can be produced according to the difference of number of electrodes, be applicable to the needs of different length endoscopy disinfection process; (2) adopt He, Ne, Ar rare gas to be main discharge gas, plasma can keep low temperature, even, discharge voltage is low, and can not produce creeping discharge at endoscope's outer wall, and adulterate N simultaneously on a small quantity
2, O
2, H
2the strong active gases such as O, can strengthen plasma active further; (3) produce plasma according to pulse power excitation, then discharge gas can select the strong active gases that air (containing humid air), oxygen etc. are cheap; (4) using plasma fluidic architecture, reduce further discharge voltage and plasma temperature, and plasma jet can be suitable for the endoscopy disinfection process of different bore size; (5) active particle density is high, and therefore treatment effeciency is high, in a few minutes even less than the treatment effect that can obtain in a minutes; (6) plasma jet produced can not produce damage by endoscope inner surface; (7) plasma producing apparatus under atmospheric pressure operates, and without the need to vacuum chamber, equipment is simple, easy to operate, cheap, and plasma treated after can not produce toxic residue.
Apply specific case herein to set forth principle of the present invention and embodiment, the explanation of above embodiment just understands method of the present invention and core concept thereof for helping; Meanwhile, for those skilled in the art, according to thought of the present invention, all will change in specific embodiments and applications, in sum, this description should not be construed as limitation of the present invention.
Claims (15)
1. a low temperature plasma endoscope sterilizing device, described device comprises Gas Control Module, power supply stimulating module, plasma generation module, it is characterized in that:
Described Gas Control Module controls composition proportion and the flow velocity of multiple reacting gas by multiple flow controller;
Described power supply stimulating module by high voltage power supply for described plasma generation module provides excitation;
Described plasma generation module, by the electrode structure of overlap span, produces length at 1cm to 2m, diameter at the atmosphere cold plasma jet of 0.2mm to 10mm.
2. device according to claim 1, is characterized in that: described flow controller is according to the flow of the different adjustment reacting gas of endoscope tube internal diameter.
3. device according to claim 1 and 2, is characterized in that: described reacting gas take rare gas as main discharge gas, or under pulse excitation, chooses strong active gases as discharge gas.
4. device according to claim 3, preferably, described rare gas is He, Ar, and described strong active gases is dry air, humid air or oxygen.
5. device according to claim 1 and 2, is characterized in that: the described high voltage power supply for low temperature plasma excitation is sinusoidal high voltage power supply, and frequency is not higher than 100MHz.
6. device according to claim 1 and 2, is characterized in that: described power supply stimulating module adopts pulsed high voltage generator, and its pulse frequency is between 50Hz-100MHz.
7. device according to claim 1 and 2, is characterized in that: the electrode structure of described overlap span is alternately arranged by high-field electrode and ground electrode and realizes.
8. device according to claim 1 and 2, is characterized in that: the structure of single electrode has quick assembly and disassembly type and spring screw fixed pattern two kinds.
9. device according to claim 1 and 2, is characterized in that: what described plasma generation module produced is plasma jet.
10. device according to claim 1 and 2, is characterized in that: described plasma jet structure, with spray point, reduces starting voltage.
11. devices according to claim 1 and 2, is characterized in that: endoscope channel adopts polyfluortetraethylene pipe.
12. 1 kinds of methods adopting device disinfect endoscopes according to any one of claim 1-11, is characterized in that:
Step 1, controls composition proportion and the flow velocity of multiple reacting gas by the multiple flow controllers in Gas Control Module;
Step 2, by high voltage power supply for described plasma generation module provides excitation;
Step 3, plasma generation module, by the electrode structure of overlap span, produces length at 1cm to 2m, diameter at the atmosphere cold plasma jet of 0.2mm to 10mm, for endoscopy disinfection.
13. methods as claimed in claim 12, is characterized in that: obtain atmosphere cold plasma by the mode of jet.
14. methods as claimed in claim 12, is characterized in that: by being produce electric discharge in main mist at rare gas, strengthen active particle kind and quantity in plasma.
15. methods as claimed in claim 12, is characterized in that: the electrode structure utilizing overlap span, reduce discharge voltage and plasma temperature.
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| FR3026303B1 (en) * | 2014-09-25 | 2018-05-11 | Plasmabiotics | DRYING METHOD OF MEDICAL DEVICE |
| CN104372028B (en) * | 2014-11-10 | 2017-04-26 | 西安交通大学 | Method for transfecting exogenous nucleic acid by use of atmospheric pressure cold plasma jet |
| CN104735893B (en) * | 2015-03-31 | 2017-10-20 | 西安交通大学 | A kind of low temperature plasma is used for the apparatus and method that slender pipeline sterilizes |
| EP3813495A1 (en) * | 2015-09-07 | 2021-04-28 | Plasmatica Ltd. | Preventing fog on a medical device viewport |
| US11896204B2 (en) | 2015-09-07 | 2024-02-13 | Plasmatica Ltd. | Methods and systems for providing plasma treatments to optical surfaces |
| US11896203B2 (en) | 2015-09-07 | 2024-02-13 | Plasmatica Ltd. | Methods and systems for providing plasma treatments to optical surfaces |
| CN105833327A (en) * | 2016-03-25 | 2016-08-10 | 威海柏林圣康空氧科技有限公司 | Method of quick sterilization through oxygen activation |
| CN106693009B (en) * | 2016-12-26 | 2023-06-27 | 大连顺达微创科技有限公司 | Atmospheric pressure flexible cold plasma jet endoscope sterilization device and method |
| CN108310399A (en) * | 2017-01-16 | 2018-07-24 | 深圳市先赞科技有限公司 | A kind of medical endoscope Double-sterilization method |
| CN111556762A (en) * | 2017-12-30 | 2020-08-18 | 3M创新有限公司 | Plasma sterilization and drying system and method |
| CN108342896B (en) * | 2018-02-13 | 2019-12-31 | 南通大学 | Plasma treatment device for inner and outer surfaces of tubular fabric and using method thereof |
| CN110538334B (en) * | 2019-08-09 | 2021-04-09 | 西安交通大学 | Plasma sterilization and anti-infection device based on argon and ethanol mixed gas |
| CN112931761B (en) * | 2021-04-20 | 2023-06-02 | 山东大学 | Tea pesticide residue degradation and disinfection device and method based on atmospheric pressure cold plasma |
| CN113692100B (en) * | 2021-08-09 | 2023-03-24 | 江苏容正医药科技有限公司 | Multi-section electrode plasma jet triggering method applied to endoscope inner wall disinfection |
| CN114306692A (en) * | 2021-12-30 | 2022-04-12 | 老肯医疗科技股份有限公司 | Hydrogen peroxide plasma sterilizer capable of efficiently sterilizing and sterilization method |
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