CN106693009B - Atmospheric pressure flexible cold plasma jet endoscope sterilization device and method - Google Patents
Atmospheric pressure flexible cold plasma jet endoscope sterilization device and method Download PDFInfo
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- CN106693009B CN106693009B CN201611216586.0A CN201611216586A CN106693009B CN 106693009 B CN106693009 B CN 106693009B CN 201611216586 A CN201611216586 A CN 201611216586A CN 106693009 B CN106693009 B CN 106693009B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/14—Plasma, i.e. ionised gases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/11—Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/24—Medical instruments, e.g. endoscopes, catheters, sharps
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Abstract
The invention relates to the field of disinfection and sterilization in the medical industry, in particular to an atmospheric pressure flexible cold plasma jet endoscope sterilization device and method. The endoscope is immersed in a catheter-type sterilization area filled with atmospheric pressure flexible cold plasma jet, microorganisms on the surface of the endoscope can be killed by the atmospheric pressure flexible cold plasma jet, the catheter-type sterilization area is non-closed and independent of a plasma electrode discharge area, and the plasma electrode discharge area is used for generating flexible cold plasma jet. The method can change the size and shape of the catheter, and can realize sterilization of soft and hard endoscopes with different sizes without changing the electrode structure. The sterilization method does not need complex vacuum equipment, has low cost and high efficiency, does not need chemical reagents, has no pollution to the environment, and is a low-cost and high-efficiency green endoscope sterilization method.
Description
Technical Field
The invention relates to the field of disinfection and sterilization in the medical industry, in particular to an atmospheric pressure flexible cold plasma jet endoscope sterilization device and method.
Background
Endoscopes are an important medical device for viewing lumens in the human and animal body and have been used clinically for the diagnosis and treatment of a variety of diseases. Before using the endoscope, it is sterilized to prevent cross infection. Various methods have been used to sterilize endoscopes, such as high temperature and high pressure steam, ethylene oxide fumigation, glutaraldehyde soaking, low temperature plasma sterilization, and the like. The high-temperature high-pressure steam method has higher sterilization temperature, is easy to cause thermal damage to the surface of an endoscope, and is difficult to effectively inactivate some pathogenic microorganisms. The sterilization process of the ethylene oxide fumigation method requires a longer period of ventilation, resulting in a longer overall sterilization cycle. In addition, ethylene oxide is toxic, inflammable and explosive, and once the ethylene oxide remains or leaks, the improper treatment causes safety accidents; thus, there is a serious safety hazard in using the sterilization. The glutaraldehyde soaking method generally needs to be soaked for more than ten hours, and the sterilization efficiency is low; glutaraldehyde has strong irritation, and can irritate skin and mucous membrane, leading to human allergy; when the waste liquid is discharged, the water body is polluted.
The low-temperature plasma sterilization utilizes active particles in the plasma to kill pathogenic microorganisms, does not need chemical reagents during sterilization, has no pollution to the environment, has good treatment effect and high efficiency, has less damage to the surface of an endoscope, and is an ideal endoscope sterilization method. Document (Zentralblatt fur Hygiene und Umweltmedizin 1993, 194 (4): 380-391) provides an apparatus and method for sterilizing an endoscope using hydrogen peroxide plasma, and a sterrad 100s endoscope sterilization system developed based thereon has been widely used worldwide. However, the device and the method require expensive and complex vacuum equipment, have higher cost, and in actual treatment, the device and the method need to vacuumize, inject hydrogen peroxide and then sterilize, so that the sterilization efficiency is reduced; in addition, such devices are difficult to sterilize long or thin endoscopes. The method for sterilizing the endoscope by adopting the sterilization device with a simpler structure and low-cost gas has not been reported so far. In addition, if the plasma electrode discharge region and the sterilization region are separated, the temperature of the sterilization region can be reduced, and the catheter size can be easily changed to accommodate endoscopes of different sizes, but the endoscope sterilization device has not been realized so far.
Disclosure of Invention
In order to solve the technical problems that a plasma electrode discharge area and a jet sterilization area cannot be separated and the endoscope cannot be sterilized in a short time under the atmospheric pressure in the prior art, the invention provides a method for realizing the sterilization of an atmospheric pressure flexible cold plasma jet endoscope. The invention further aims to provide a device for realizing sterilization of the atmospheric flexible cold plasma jet endoscope, which is simple in structure and low in cost.
In order to achieve the above purpose, the invention adopts the following technical scheme: the method for sterilizing the atmospheric pressure flexible cold plasma jet endoscope is characterized in that the endoscope is immersed in a conduit type sterilization area filled with the atmospheric pressure flexible cold plasma jet, microorganisms on the surface of the endoscope can be killed by the atmospheric pressure flexible cold plasma jet, the conduit type sterilization area is non-closed and independent of a plasma electrode discharge area, and the plasma electrode discharge area is used for generating the flexible cold plasma jet.
The method comprises the following specific steps: inserting the endoscope into the catheter sterilization zone, and introducing and filling the catheter sterilization zone with the atmospheric pressure flexible cold plasma jet generated in the plasma electrode discharge zone to sterilize the endoscope.
The working gas of the atmospheric flexible cold plasma jet comprises nitrogen, oxygen, argon, helium, air or a mixed gas of the above gases.
The discharge form of the atmospheric flexible cold plasma jet comprises one of bare electrode discharge, dielectric barrier discharge and hollow cathode discharge.
The size and shape of the atmospheric flexible cold plasma jet flow are determined by the catheter type sterilization area, the catheter of the catheter type sterilization area can be adjusted according to the size and shape of the endoscope, and the sterilization of soft and hard endoscopes with different sizes can be realized on the premise of not changing the structures of the electrode and the plasma electrode discharge area.
The catheter is made of one of polytetrafluoroethylene, PMMA (polymethyl methacrylate), quartz glass, silicate glass, PC (polycarbonate), PEEK (polyether ether ketone), PI (polyimide) and TPU (thermoplastic polyurethane elastomer rubber), and is used for placing the endoscope, wherein the endoscope is of a horizontal or vertical or bent circular tube structure, the length of the circular tube structure is 20-1500mm, and the diameter of the circular tube structure is 2-20mm.
The horizontal circular tube structure and the vertical circular tube structure are respectively a straight circular tube structure which is arranged horizontally and vertically, and are suitable for sterilizing the hard endoscope, and the bending circular tube structure is a circular tube structure which is arranged vertically and has a wave-shaped radian, and is suitable for sterilizing the soft endoscope.
The atmospheric pressure flexible cold plasma jet endoscope sterilization device is characterized by comprising a catheter type sterilization area and a plasma electrode discharge area which are mutually independent, wherein the catheter type sterilization area comprises a catheter for placing an endoscope, an atmospheric pressure flexible cold plasma jet for immersing and sterilizing the endoscope exists in the catheter, an exhaust hole is formed in the upper end of the catheter, working gas of the atmospheric pressure flexible cold plasma jet is emitted by a working gas source in the plasma electrode discharge area and sequentially passes through a pressure reducing valve and an adjustable flowmeter and then is introduced into a cold plasma jet generator, an outlet of the cold plasma jet generator is connected with the catheter, and corresponding electrodes of the cold plasma jet generator are respectively connected with an output end of a high-voltage power supply.
The diameter of the outlet of the cold plasma jet generator is 2-6mm, and the discharge form of the corresponding electrode comprises one of a bare electrode type, a dielectric barrier type and a hollow cathode type.
The high-voltage power supply is one of a high-voltage direct-current power supply, a high-voltage radio-frequency power supply, a microwave power supply, a high-voltage low-frequency alternating-current power supply and a high-voltage pulse power supply, and the output voltage is 0-10kV.
The catheter is made of one of polytetrafluoroethylene, PMMA (polymethyl methacrylate), quartz glass, silicate glass, PC (polycarbonate), PEEK (polyether ether ketone), PI (polyimide) and TPU (thermoplastic polyurethane elastomer rubber), and is used for placing an endoscope, and the catheter is of a horizontal or vertical or curved circular tube structure, wherein the length of the circular tube structure is 20-1500mm, and the diameter of the circular tube structure is 2-20mm.
The horizontal circular tube structure and the vertical circular tube structure are respectively a straight circular tube structure which is arranged horizontally and vertically, and are suitable for sterilizing the hard endoscope.
The bending type circular tube structure is a circular tube structure which is vertically arranged and provided with a wave-shaped radian, and is suitable for sterilizing a soft endoscope.
The radius of the circle corresponding to the wave-shaped radian is 20-200 mm, and the central angle is 30-90 degrees.
The working gas is one or more than one gas selected from nitrogen, oxygen, argon, helium and air.
The working gas enters the cold plasma jet generator at a flow rate of 10-40L/min.
The invention has the advantages that:
(1) The flexible cold plasma jet contains a large amount of active particles such as high-speed electrons, ions, strong oxidizing atoms, excited molecules, free radicals and the like, has higher chemical activity, can oxidize amino sugar in protein chains in microorganisms in a short time, kills the microorganisms, and realizes high-efficiency sterilization without chemical reagents;
(2) The method can use different working gases for sterilization, and can select gases with relatively low oxidation property if necessary, such as: nitrogen, helium, etc. to avoid aging of the endoscope rubber during sterilization;
(3) The flexible cold plasma jet sterilization area of the immersed endoscope is at a certain distance from the plasma electrode discharge area, the macroscopic temperature of the flexible cold plasma jet sterilization area is as low as room temperature, and the heat damage to the endoscope can not be generated;
(4) The method can realize sterilization of soft and hard endoscopes with different sizes by changing the size and shape of the catheter without changing the structures of the electrodes and the discharge areas;
(5) The method does not need complicated vacuum equipment, can use nitrogen for sterilization, has relatively low cost, simple and flexible operation and no pollution to the environment, and is a low-cost and high-efficiency green sterilization method.
Drawings
Fig. 1 is a schematic view (catheter horizontal) of an atmospheric flexible cold plasma jet endoscope sterilization apparatus for sterilizing a hard endoscope.
Fig. 2 is a schematic view of an atmospheric flexible cold plasma jet endoscope sterilization apparatus for sterilizing a hard endoscope (catheter stand).
Fig. 3 is a schematic view of an atmospheric pressure flexible cold plasma jet endoscope sterilization apparatus for sterilizing a soft endoscope (catheter bending).
FIG. 4 is a graph of colonies on the surface of an endoscope before and after flexible cold plasma jet sterilization under a microscope.
In the figure: 1-a source of working gas; 2-a pressure reducing valve; 3-an adjustable flowmeter; a 4-cold plasma jet generator; 5-a high voltage power supply; 6-a catheter; 7-an endoscope; 8-atmosphere flexible cold plasma jet; 9-exhaust holes; (a) and (b) are colonies before sterilization; (c) and (d) are colonies after 1min sterilization.
Description of the embodiments
The present invention will be described in detail below with reference to the accompanying drawings, but the present invention is not limited to the specific embodiments.
Example 1
The atmospheric pressure flexible cold plasma jet endoscope sterilization device shown in fig. 1 comprises a catheter type sterilization area and a plasma electrode discharge area which are independent from each other, wherein the catheter type sterilization area comprises a catheter 6 for placing an endoscope 7, an atmospheric pressure flexible cold plasma jet 8 for immersing and sterilizing the endoscope 7 exists in the catheter 6, an exhaust hole 9 is formed in the upper end of the catheter 6, in the plasma electrode discharge area, working gas of the atmospheric pressure flexible cold plasma jet 8 is emitted by a working gas source 1 and sequentially passes through a pressure reducing valve 2 and an adjustable flowmeter 3 and then is introduced into a cold plasma jet generator 4, an outlet of the cold plasma jet generator 4 is connected with the catheter 6, and corresponding electrodes of the cold plasma jet generator 4 are respectively connected with an output end of a high-voltage power supply 5.
The diameter of the outlet of the cold plasma jet generator 4 is 4mm, and the discharge form of the corresponding electrode is a bare electrode.
The high-voltage power supply 5 is a high-voltage low-frequency alternating current power supply with the frequency of 30kHz-100kHz, the output voltage of 0-10kV and the maximum power of 500W.
The catheter 6 is made of PMMA, the part for placing the endoscope 7 is of a horizontal circular tube structure, the horizontal circular tube structure is of a straight circular tube structure which is horizontally arranged, the length of the circular tube structure is 320mm, and the diameter of the circular tube structure is 10mm.
Example 2
An atmospheric pressure flexible cold plasma jet endoscope sterilization method is characterized in that an endoscope is immersed in a catheter type sterilization area filled with atmospheric pressure flexible cold plasma jet, microorganisms on the surface of the endoscope can be killed by the atmospheric pressure flexible cold plasma jet, the catheter type sterilization area is non-closed and independent of a plasma electrode discharge area, and the plasma electrode discharge area is used for generating the flexible cold plasma jet. In this embodiment, the device pair described in embodiment 1 is used to implement the method, in this embodiment, the endoscope is a cystoscope with a length of 305mm and a diameter of 4mm, and is a hard endoscope, and the working gas is high-purity nitrogen with a purity of 99.999%, and the specific steps are as follows:
the first step: the parts of the device were connected as described in example 1:
and a second step of: slowly inserting the endoscope 7 to be disinfected into the catheter 6;
and a third step of: the pressure reducing valve 2 is opened, the adjustable flowmeter 3 to 20L/min is regulated, nitrogen is smoothly introduced into the cold plasma jet generator 4, the cold plasma jet generator 4 uses a bare electrode discharge form, plasma jet generated by the discharge form cannot generate breakdown discharge with conductors such as metal, and the macroscopic temperature is room temperature, so that the insulation and heat resistance of the catheter 6, the endoscope 7, and the like are not particularly required;
fourth step: the high-voltage power supply 5 is started, the output frequency is adjusted to be 60.0 kHz, the atmospheric pressure flexible cold plasma jet 8 is generated in the cold plasma jet generator 4, the output voltage is gradually increased from zero until the atmospheric pressure flexible cold plasma jet 8 is full of the guide pipe 6 and is discharged through the exhaust hole 9, and at the moment, the endoscope 7 is completely immersed in the atmospheric pressure flexible cold plasma jet 8, so that sterilization is realized.
FIG. 4 is a view of colonies on the surface of an endoscope before and after flexible cold plasma jet sterilization under a microscope; the bacterial colonies before sterilization and the bacterial colonies after 1min sterilization can be seen that most of bacteria are killed after 1min treatment, and the sterilization effect is remarkable.
Example 3
The atmospheric pressure flexible cold plasma jet endoscope sterilization device shown in fig. 2 comprises a catheter type sterilization area and a plasma electrode discharge area which are independent from each other, wherein the catheter type sterilization area comprises a catheter 6 for placing an endoscope 7, an atmospheric pressure flexible cold plasma jet 8 for immersing and sterilizing the endoscope 7 exists in the catheter 6, an exhaust hole 9 is formed in the upper end of the catheter 6, in the plasma electrode discharge area, working gas of the atmospheric pressure flexible cold plasma jet 8 is emitted by a working gas source 1 and sequentially passes through a pressure reducing valve 2 and an adjustable flowmeter 3 and then is introduced into a cold plasma jet generator 4, an outlet of the cold plasma jet generator 4 is connected with the catheter 6, and corresponding electrodes of the cold plasma jet generator 4 are respectively connected with an output end of a high-voltage power supply 5.
The diameter of the outlet of the cold plasma jet generator 4 is 2mm, and the discharge form of the corresponding electrode is dielectric barrier type.
The high-voltage power supply 5 is a high-voltage radio-frequency power supply with the frequency of 2MHz-41MHz, the output voltage of 0-10kV and the maximum power of 300W.
The catheter 6 is made of quartz glass, the portion for placing the endoscope 7 is of a vertical circular tube structure, the vertical circular tube structure is of a vertical straight circular tube structure, the length of the circular tube structure is 200mm, and the diameter of the circular tube structure is 6mm.
Example 4
A method of sterilizing an endoscope using the apparatus of example 3, in which the endoscope is a paranasal sinus mirror having a length of 180mm and a diameter of 2.7mm, is a hard endoscope, and the working gas is high purity helium gas having a purity of 99.999%, comprising the steps of:
the first step: the parts of the device were connected as described in example 3:
and a second step of: slowly inserting the endoscope 7 to be disinfected into the catheter 6;
and a third step of: opening a pressure reducing valve 2, adjusting an adjustable flowmeter 3 to 12L/min, and smoothly introducing helium into a cold plasma jet generator 4, wherein the cold plasma jet generator 4 adopts a dielectric barrier discharge mode, and the concentration of plasma active particles generated by the discharge mode is higher, so that the sterilization efficiency is also higher;
fourth step: the high-voltage power supply 5 is started, the output frequency is adjusted to 13.56MHz, the atmospheric pressure flexible cold plasma jet 8 is generated in the cold plasma jet generator 4, the output voltage is gradually increased from zero until the atmospheric pressure flexible cold plasma jet 8 is filled with the guide pipe 6 and is discharged through the exhaust hole 9, and at the moment, the endoscope 7 is completely immersed in the atmospheric pressure flexible cold plasma jet 8, so that the sterilizing effect similar to that in the embodiment 2 is realized.
Example 5
The atmospheric pressure flexible cold plasma jet endoscope sterilization device shown in fig. 3 comprises a catheter type sterilization area and a plasma electrode discharge area which are independent from each other, wherein the catheter type sterilization area comprises a catheter 6 for placing an endoscope 7, an atmospheric pressure flexible cold plasma jet 8 for immersing and sterilizing the endoscope 7 exists in the catheter 6, an exhaust hole 9 is formed in the upper end of the catheter 6, in the plasma electrode discharge area, working gas of the atmospheric pressure flexible cold plasma jet 8 is emitted by a working gas source 1 and sequentially passes through a pressure reducing valve 2 and an adjustable flowmeter 3 and then is introduced into a cold plasma jet generator 4, an outlet of the cold plasma jet generator 4 is connected with the catheter 6, and corresponding electrodes of the cold plasma jet generator 4 are respectively connected with an output end of a high-voltage power supply 5.
The diameter of the outlet of the cold plasma jet generator 4 is 6mm, and the discharge form of the corresponding electrode is hollow cathode.
The high-voltage power supply 5 is a microwave power supply with the frequency of 500MHz-5GHz, the output voltage of 0-10kV and the maximum power of 500W.
The material of pipe 6 is polytetrafluoroethylene, and its part that is used for placing endoscope 7 is curved pipe structure, curved pipe structure is vertical setting and has the pipe structure of wave radian, the circle radius that wave radian corresponds is 100mm, and the central angle is 45 degrees, the length of pipe structure is 1500mm, and the diameter is 20mm.
Example 6
A method for sterilizing an endoscope by using the device in embodiment 5, wherein the endoscope is a gastroscope with a working length of 1100mm and a diameter of 5.9mm, and is a soft endoscope, and the working gas is a mixed gas of helium and oxygen, wherein the volume fraction of the oxygen is 1%, and the method specifically comprises the following steps:
the first step: the parts of the device were connected as described in example 5:
and a second step of: slowly inserting the endoscope 7 to be disinfected into the catheter 6;
and a third step of: opening a pressure reducing valve 2, adjusting an adjustable flowmeter 3 to 35L/min, and smoothly introducing the mixed gas into a cold plasma jet generator 4, wherein the cold plasma jet generator 4 uses a hollow cathode discharge form, and the discharge form is glow discharge with higher particle density;
fourth step: the high-voltage power supply 5 is started, the output frequency is adjusted to be 2.4GHz, the atmospheric pressure flexible cold plasma jet 8 is generated in the cold plasma jet generator 4, the output voltage is gradually increased from zero until the atmospheric pressure flexible cold plasma jet 8 is filled with the guide pipe 6 and is discharged through the exhaust hole 9, and at the moment, the endoscope 7 is completely immersed in the atmospheric pressure flexible cold plasma jet 8, so that the sterilizing effect similar to that in the embodiments 2 and 4 is realized.
Claims (1)
1. An atmospheric pressure flexible cold plasma jet endoscope sterilization method is characterized in that an endoscope is immersed in a conduit type sterilization area filled with atmospheric pressure flexible cold plasma jet, microorganisms on the surface of the endoscope can be killed by the atmospheric pressure flexible cold plasma jet, the conduit type sterilization area is non-closed and independent of a plasma electrode discharge area, and the plasma electrode discharge area is used for generating the flexible cold plasma jet;
the method comprises the following specific steps: inserting the endoscope into the catheter sterilization zone, and enabling the atmospheric pressure flexible cold plasma jet generated in the plasma electrode discharge zone to enter and fill the catheter sterilization zone to sterilize the endoscope;
the working gas of the atmospheric flexible cold plasma jet comprises nitrogen, oxygen, argon, helium, air or the mixed gas of the above gases; the working gas enters a cold plasma jet generator at a flow rate of 10-40L/min;
the discharge form of the atmospheric pressure flexible cold plasma jet comprises one of bare electrode discharge, dielectric barrier discharge and hollow cathode discharge;
the size and the shape of the atmospheric flexible cold plasma jet flow are determined by the catheter type sterilization area, the catheter of the catheter type sterilization area can be adjusted according to the size and the shape of the endoscope, and the sterilization of soft and hard endoscopes with different sizes can be realized on the premise of not changing the structures of the electrode and the plasma electrode discharge area;
the catheter is made of one of polytetrafluoroethylene, polymethyl methacrylate, quartz glass, silicate glass, polycarbonate, polyether-ether-ketone, polyimide and thermoplastic polyurethane elastomer rubber, and is used for placing the endoscope, wherein the part of the catheter is of a horizontal or vertical or curved circular tube structure, the length of the circular tube structure is 20-1500mm, and the diameter of the circular tube structure is 2-20mm;
the horizontal circular tube structure and the vertical circular tube structure are respectively a straight circular tube structure which is arranged horizontally and vertically and is suitable for sterilizing the hard endoscope, the bending circular tube structure is a circular tube structure which is arranged vertically and has a wave-shaped radian and is suitable for sterilizing the soft endoscope, the radius of a circle corresponding to the wave-shaped radian is 20-200 mm, and the central angle is 30-90 degrees;
the atmospheric pressure flexible cold plasma jet endoscope sterilization device adopted by the sterilization method is characterized by comprising a catheter type sterilization area and a plasma electrode discharge area which are mutually independent, wherein the catheter type sterilization area comprises a catheter (6) used for placing an endoscope (7), an atmospheric pressure flexible cold plasma jet (8) used for immersing and sterilizing the endoscope (7) exists in the catheter (6), an exhaust hole (9) is formed in the upper end of the catheter (6), working gas of the atmospheric pressure flexible cold plasma jet (8) is emitted by a working gas source (1) in the plasma electrode discharge area and sequentially passes through a pressure reducing valve (2) and an adjustable flowmeter (3) and then is introduced into a cold plasma jet generator (4), an outlet of the cold plasma jet generator (4) is connected with the catheter (6), and corresponding electrodes of the cold plasma jet generator (4) are respectively connected with the output end of a power supply (5);
the diameter of the outlet of the cold plasma jet generator (4) is 2-6mm, and the discharge form of the corresponding electrode comprises one of a bare electrode type, a dielectric barrier type and a hollow cathode type;
the high-voltage power supply (5) is one of a high-voltage direct-current power supply, a high-voltage radio-frequency power supply, a microwave power supply, a high-voltage low-frequency alternating-current power supply and a high-voltage pulse power supply, and the output voltage is 0-10kV;
the high-voltage low-frequency alternating current power supply has the frequency of 30kHz-100kHz and the maximum power of 500W; the high-voltage radio frequency power supply has the frequency of 2MHz-41MHz and the maximum power of 300W; the microwave power supply has the frequency of 500MHz-5GHz and the maximum power of 500W.
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| CN107114648A (en) * | 2017-05-31 | 2017-09-01 | 安徽沃兰朵电源技术有限公司 | A kind of device sterilized for PET |
| CN111642052B (en) * | 2020-07-15 | 2022-02-08 | 安徽工业大学 | Flexible slender microplasma jet source and using method |
| CN114554670B (en) * | 2022-02-14 | 2022-11-29 | 西安电子科技大学 | Plasma jet system and control method |
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| CN103585650B (en) * | 2013-07-09 | 2016-04-06 | 西安交通大学 | A kind of low temperature plasma endoscope sterilizing device and method |
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| CN206761952U (en) * | 2016-12-26 | 2017-12-19 | 大连顺达微创科技有限公司 | A kind of atmospheric pressure flexibility cold-plasma jet endoscope sterilization device |
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| JP2003210556A (en) * | 2002-01-18 | 2003-07-29 | Toshiba Corp | Pipe sterilizer with plasma |
| JP2005046264A (en) * | 2003-07-31 | 2005-02-24 | Toshiba Corp | Sterilization apparatus and method for pipe |
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