Summary of the invention
The object of this invention is to provide the preparation method that is used for the treatment of the medicament of decubital ulcer in a kind of clinical care.
In order to realize object of the present invention, the invention provides the preparation method that is used for the treatment of the medicament of decubital ulcer in a kind of clinical care, the method comprises the following steps: to get 6 grams of 6 grams of Folium Symplocoris Caudataes, 7 grams of Radix Zanthoxyli Spinifoliis, 15 grams of Fructus Forsythiaes, 8 grams of Caulis Seu Folium Euonymi Fortuneis, 10 grams, Semen Armeniacae Amarum, 3 grams of sanicles, 15 grams of Flos Loniceraes, 4 grams, prairie fire rope, 10 grams of Radix Bupleuri, 6 grams of Herba clerodendranthi spicati, 4 grams of Herba Epimedii, 3 grams of longestapex beautyberry leafs, 6 grams of Rhizoma Atractylodis, 7 grams of ipomoea cairica, 8 grams of Rhizoma Alismatis and the Cortexs Eucommiae, add 6000 milliliters, water, in being housed, at 90 ℃, heats 5 hours by the flask of condensing tube, filter, filtrate is described medicament.
Preferably, described medicament can be tablet, dispersible tablet, capsule or decoction.
With reference to < < Chinese medicine voluminous dictionary > > second edition, being described as follows of some crude drug that use in the present invention:
Whole compositions of the medicament that the method for the invention makes are all natural materials, and safety is better, and curative effect is clear and definite, are suitable for large-scale promotion clinically.
The specific embodiment
Below by embodiment, further illustrate the present invention.It should be understood that embodiments of the invention are for the present invention rather than limitation of the present invention are described.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the scope of protection of present invention.Except as otherwise noted, the percent otherwise in the present invention is percetage by weight.
Embodiment decoction of the present invention
Get 6 grams of 6 grams of Folium Symplocoris Caudataes, 7 grams of Radix Zanthoxyli Spinifoliis, 15 grams of Fructus Forsythiaes, 8 grams of Caulis Seu Folium Euonymi Fortuneis, 10 grams, Semen Armeniacae Amarum, 3 grams of sanicles, 15 grams of Flos Loniceraes, 4 grams, prairie fire rope, 10 grams of Radix Bupleuri, 6 grams of Herba clerodendranthi spicati, 4 grams of Herba Epimedii, 3 grams of longestapex beautyberry leafs, 6 grams of Rhizoma Atractylodis, 7 grams of ipomoea cairica, 8 grams of Rhizoma Alismatis and the Cortexs Eucommiae, add 5000 milliliters, water, in being housed, at 90 ℃, heats 5 hours by the flask of condensing tube, filter, filtrate is decoction of the present invention.
Experimental example
One, patient's data
The criterion of decubital ulcer
I degree: pressurized position skin rubefaction, epidermis is rotten to the corn, oozes out on a small quantity.II degree: skin holostrome ulceration, but subcutaneous tissue not yet involves.III degree: skin ulceration reaches subcutaneous tissue deeply, involves fascia and muscle, but deep layer osseous tissue is not got involved.IV degree: deeply reach osseous tissue, accompany osteonecrosis and infection simultaneously.
Choose patient's 48 examples that decubital ulcer occurs, age 45-98 year, average 78.69 years old.Wherein, male 20 examples, female's 28 examples.Tail sacrum portion 33 examples, account for 68.8%, and hip 8 examples, account for 16.7%, and back 2 examples, account for 4.2%, and ankle and foot 5 examples, account for 10.4%.MethodsThe cases enrolled all meets the criterion of decubital ulcer.
Use the decoction of preparing in embodiment to treat, every day 1 time, each oral 100 milliliters.Treat 7 days is 1 course for the treatment of.
Three, efficacy assessment standard
With reference to < < disease of tcm Standardization of diagnosis and curative effect > >, formulate following efficacy assessment standard.Recovery from illness: wound surface epithelium covers completely, and cicatrix is solid, observed wound surface through 1 week and does not fester again; Effective: wound surface dwindles >75%, granulation tissue is fresh, remission; Take a turn for the better: wound surface dwindles >25%, and <75%, granulation tissue comparatively fresh, symptom is improved; Invalid: though wound surface is front fresh, dwindle <25%, and granulation tissue growth seldom.
Four, result
Through treatment, 48 routine wounds epitheliums cover completely, and cicatrix is solid, observe wound surface do not fester again through 1 week, therefore all meet the standard of recovery from illness.
Six, untoward reaction
For 48 routine patients, in therapeutic process, carry out tracing observation, do not find obvious untoward reaction.