Summary of the invention
The object of this invention is to provide the preparation method of the medicament a kind of clinical care being used for the treatment of decubital ulcer.
In order to realize object of the present invention, the invention provides the preparation method of the medicament a kind of clinical care being used for the treatment of decubital ulcer, the method comprises the following steps: to get Folium Symplocoris Caudatae 6 grams, Radix Zanthoxyli Spinifolii 7 grams, Fructus Forsythiae 15 grams, Caulis Seu Folium Euonymi Fortunei 8 grams, 10 grams, Semen Armeniacae Amarum, sanicle 3 grams, Flos Lonicerae 15 grams, 4 grams, prairie fire rope, Radix Bupleuri 10 grams, Herba clerodendranthi spicati 6 grams, Herba Epimedii 4 grams, longestapex beautyberry leaf 3 grams, Rhizoma Atractylodis 6 grams, ipomoea cairica 7 grams, Rhizoma Alismatis 8 grams and the Cortex Eucommiae 6 grams, add 6000 milliliters, water, heat 5 hours at 90 DEG C in the flask that condensing tube is housed, filter, filtrate is described medicament.
Preferably, described medicament can be tablet, dispersible tablet, capsule or decoction.
With reference to " Chinese medicine voluminous dictionary " second edition, being described as follows of some crude drug used in the present invention:
Whole compositions of the medicament that the method for the invention obtains are all natural materials, and safety is better, and clear curative effect, is suitable for large-scale promotion clinically.
Embodiment decoction of the present invention
Get Folium Symplocoris Caudatae 6 grams, Radix Zanthoxyli Spinifolii 7 grams, Fructus Forsythiae 15 grams, Caulis Seu Folium Euonymi Fortunei 8 grams, 10 grams, Semen Armeniacae Amarum, sanicle 3 grams, Flos Lonicerae 15 grams, 4 grams, prairie fire rope, Radix Bupleuri 10 grams, Herba clerodendranthi spicati 6 grams, Herba Epimedii 4 grams, longestapex beautyberry leaf 3 grams, Rhizoma Atractylodis 6 grams, ipomoea cairica 7 grams, Rhizoma Alismatis 8 grams and the Cortex Eucommiae 6 grams, add 5000 milliliters, water, heat 5 hours at 90 DEG C in the flask that condensing tube is housed, filter, filtrate is decoction of the present invention.
Experimental example
One, patient data
The criterion of decubital ulcer
I degree: pressurized position skin rubefaction, epidermis is rotten to the corn, oozes out on a small quantity.II degree: skin holostrome ulceration, but subcutaneous tissue not yet involves.III degree: skin ulceration reaches subcutaneous tissue deeply, involves fascia and muscle, but deep layer osseous tissue is not got involved.IV degree: deeply reach osseous tissue, accompanies osteonecrosis and infection simultaneously.
Choose occur decubital ulcer patient 48 example, age 45-98 year, average 78.69 years old.Wherein, man 20 example, female 28 example.Tail sacrum portion 33 example, accounts for 68.8%, and hip 8 example, accounts for 16.7%, and back 2 example, accounts for 4.2%, and ankle and foot 5 example, accounts for 10.4%.MethodsThe cases enrolled all meets the criterion of decubital ulcer.
The decoction prepared in embodiment is used to treat, every day 1 time, oral 100 milliliters at every turn.Treat 7 days is 1 course for the treatment of.
Three, efficacy assessment standard
Following efficacy assessment standard is formulated with reference to " disease of tcm Standardization of diagnosis and curative effect ".Recovery from illness: wound surface epithelium covers completely, and cicatrix is solid, observed wound surface through 1 week and does not fester again; Effective: wound surface reduces >75%, granulation tissue is fresh, remission; Take a turn for the better: wound surface reduces >25%, and <75%, granulation tissue comparatively fresh, symptom is improved; Invalid: though wound surface is comparatively front fresh, reduce <25%, and granulation tissue growth seldom.
Four, result
Through treatment, 48 routine wounds epitheliums cover completely, and cicatrix is solid, observe wound surface and do not fester again, therefore all meet the standard of recovery from illness through 1 week.
Six, untoward reaction
Over the course for the treatment of tracing observation is carried out for 48 routine patients, does not find obvious untoward reaction.