CN103550544A - Traditional Chinese medicine composition for treating leukoplakia vulva, decoction method thereof and device for atomization treatment of diseased region - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating leukoplakia vulva, a decoction method of the traditional Chinese medicine composition, and a device for the atomization treatment of a diseased region. The traditional Chinese medicine composition I comprises 25-45g of kuh-seng, 55-75g of salvia miltiorrhiza, 10-35g of golden cypress, 35-50g of fructus cnidii, 60-75g of fructus kochiae, 7-9g of Chinese angelica, 6-8g of astragalus mongholicus, 10-15g of daemonorops draco, 10-15g of parasitic loranthus, 5-9g of windflower, 35-40g of belamcanda sinensis, 10-20g of dried rehamnnia root, 30-40g of fructus psoraleae, 20-25g of teasel root, 10-35g of musk, 5-8g of radix lithospermi, 6-9g of herba celiptae, 10-15g of bambusae caulis im taeniam and 50-70g of borneol; the traditional Chinese medicine composition II comprises 80-90g of jasmine, 50-70g of semen coicis, 30-45g of aristolochiae lignum, 25-45g of semen cuscutae, 10-20g of oriental wormwood and proper siritch. The traditional Chinese medicine composition achieves the effect of treating the leukoplakia vulva by relieving internal heat and itching, clearing heat, promoting diuresis, dredging collaterals, promoting blood circulation, and removing and constricting ecchymoses, and a patient does not feel untoward effects in a treatment process by the traditional Chinese medicine composition.

Description

The device that is used for the treatment of the Chinese medicine composition of leukoplakia vulvae and boils and diseased region atomization is processed

One, technical field

The present invention relates to a kind of device that is used for the treatment of the Chinese medicine composition of leukoplakia vulvae and boils and diseased region atomization is processed.

Two, background technology

Leukoplakia vulvae is one of gynecological clinic commonly encountered diseases and difficult disease, and common name chronic vulvar dystrophy, refers to tissue degeneratiaon, discolored a kind of disease that women's skin of vulva mucosa causes because of malnutrition.This disease can betide any age, and there are morbidity report in juvenile stage, adolescence, climacteric and geratic period, but the climacteric patient of 50 years old front and back is in the majority, and youngest daughter's disease is because of how relevant with heredity.Cardinal symptom is that pudendum is very itched, and skin of vulva mucosa bleaches, attenuation, follow the string, dry easily chap.At present, generally believe that primary disease is the pudendum local skin pathological changes being caused by many factors, the cause of disease had both comprised the local factors such as stimulating factor, neural blood vessel nutritional disorder and metabolism disorder, also comprised the impact of the factors such as infection, immunity, gonadal hormone, heredity and oxidative and anti-oxidative effect.Due to etiology unknown, there is no at present specific therapy method, also there is no a kind of device that is used for the treatment of the Chinese medicine composition of leukoplakia vulvae and boils and diseased region atomization is processed.

Three, summary of the invention

The device that the object of this invention is to provide a kind of Chinese medicine composition that is used for the treatment of leukoplakia vulvae and boil and diseased region atomization is processed, by detoxifying and relieving itching, clearing away heat-damp and promoting diuresis, dredging collateral invigorate blood circulation, the effect such as speckle removing convergence, play the effect for the treatment of leukoplakia vulvae.

For achieving the above object, the technical scheme of taking of the present invention is: the Chinese medicine composition that is used for the treatment of leukoplakia vulvae, include: Chinese medicine composition I is set to by Radix Sophorae Flavescentis 25-45 gram, Radix Salviae Miltiorrhizae 55-75 gram, Cortex Phellodendri 10-35 gram, Fructus Cnidii 35-50 gram, Fructus Kochiae 60-75 gram, Radix Angelicae Sinensis 7-9 gram, Radix Astragali 6-8 gram, Sanguis Draxonis 10-15 gram, Herba Taxilli 10-15 gram, Radix Pulsatillae 5-9 gram, Rhizoma Belamcandae 35-40 gram, Radix Rehmanniae 10-20 gram, Fructus Psoraleae 30-40 gram, Radix Dipsaci 20-25 gram, Moschus 10-35 gram, Radix Arnebiae (Radix Lithospermi) 5-8 gram, Herba Ecliptae 6-9 gram, Caulis Bambusae In Taenia 10-15 gram and Borneolum Syntheticum 50-70 gram composition, Chinese medicine composition II is set to be comprised of in right amount Fructus Gardeniae 80-90 gram, Semen Coicis 50-70 gram, Caulis Akebiae 30-45 gram, Semen Cuscutae 25-45 gram, Herba Artemisiae Scopariae 10-20 gram and siritch.

In we, take Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae, Cortex Phellodendri, Fructus Cnidii, the Fructus Kochiae, Radix Angelicae Sinensis, the Radix Astragali, Sanguis Draxonis, Herba Taxilli, the Radix Pulsatillae, Rhizoma Belamcandae, Radix Rehmanniae, Fructus Psoraleae, Radix Dipsaci, Moschus is minister, by detoxifying and relieving itching, clearing away heat-damp and promoting diuresis, dredging collateral invigorate blood circulation, speckle removing restrains, treatment leukoplakia vulvae better effects if.

The effect of Radix Sophorae Flavescentis: be the plant of pulse family Radix Sophorae Flavescentis genus.Be distributed in the ground such as each provinces and regions, north and south of Russia, Japan, India, Korea and China's Mainland, grow in the area of 1500 meters of height above sea level, how raw in hillside, sand ground, Cao Po, spinney and near field, at present not yet by artificial introducing and planting.Function cures mainly: heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment infusorian property vagina.

The effect of Radix Salviae Miltiorrhizae: Radix Salviae Miltiorrhizae has another name called Radix Salviae Miltiorrhizae, Radix Salviae Miltiorrhizae, Arisaema balansae Engl. etc.For dicotyledon Labiatae, dry root and rhizome.Main product in Anhui, the ground such as Henan, Shaanxi.Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.

The effect of Cortex Phellodendri: Cortex Phellodendri is the dry bark of rutaceae wampee or Cortex Phellodendri.The former practises title " Cortex Phellodendri ", and the latter practises title " Cortex Phellodendri ".Can be used as medicine, nature and flavor bitter cold, has heat clearing and damp drying, and pathogenic fire purging is except steaming, the effect of detoxification sore treatment.

The effect of Fructus Cnidii: Fructus Cnidii, another name Daucus carota L., is the dry mature fruit of samphire cnidium monnieri.Summer, two season of autumn gather during fruit maturation, remove impurity, dry.Nature and flavor: warm in nature, acrid in the mouth, hardship.Function cures mainly: warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, women's pudendal pruritus, trichomonal vaginitis.

The effect of the Fructus Kochiae: Fructus Kochiae fruit is oblate spheroid shape pentagon.Diameter 1～3mm.Outer by persitent perianth, surperficial celadon, around the membranous winglet of tool is 5 pieces, and there are 5～10 of the point-like fruit stem trace of micro-protuberance or radial veins in back side central authorities.Peel off the visible membranous peel of perianth, translucent.The flat avette 1mm that is about of seed, black, likeness in form Semen Sesami, expands the visible a lot of age spots of Microscopic observation.Feeble QI, mildly bitter flavor.Clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.

The effect of Radix Angelicae Sinensis: herbaceos perennial, at distribution in China in Gansu, all there is cultivation in Yunnan, Sichuan, Qinghai, Shaanxi, Hunan, Hubei, Deng Di， various places, Guizhou.The root of Radix Angelicae Sinensis can be used as medicine, and is one of the most frequently used Chinese medicine, all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.

The effect of the Radix Astragali: the plant Radix Astragali originates in the ground such as the Inner Mongol, Shanxi, Gansu, Heilungkiang, is state three level protecting plant.The Chinese crude drug Radix Astragali is the root of leguminous herbaceous plant's Radix Astagali, Radix Astragali, the medicinal history of existing more than 2000 year so far of the Radix Astragali, has invigorating QI to consolidate the body surface resistance, diuretic detumescent, expelling pus and toxin by strengthening QI, granulation promoting enhancing human body immunity function, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.

The effect of Sanguis Draxonis: Sanguis Draxonis, medicine name.Another name: black horse Lin exhausts, sea wax, dragon's blood, wooden Sanguis Draxonis.Medical material Ji Yuan: the resin in babassu Sanguis Draxonis fruit and rattan.There is promoting blood circulation and stopping pain, promoting tissue regeneration and ulcer healing, anastaltic effect.

The effect of Herba Taxilli: evergreen parasitic undershrub.Old branch, without hair, has protruding lark hole skin, and sprig is slightly by lead undercoat.Leaf alternate or be bordering on life, keratin, oval is avette to long ellipticity, long 3～8cm, wide 2～5cm, the blunt circle of tip, full edge, during children by hair; Long 1～the 1.5cm of petiole.1～3 consor axil of cyme, total bennet, bennet, calyx and corolla are all by the starlike pubescence of bronzing; Calyx is subsphaeroidal, with ovary symphysis; The narrow tubulose of corolla, slightly crooked, aubergine, tip 4 splits; Stamen 4; Berry is oval, has strumae.Florescence 8～JIUYUE, fruit 9～October of phase, invigorating the liver and kidney; Bone and muscle strengthening; Wind-damp dispelling; Antiabortive.Main soreness of waist and knee joint; A little less than muscles and bones flaccidity; Limbs are hemiplegia; Rheumatic arthralgia; Head is wrong dizzy; Frequent fetal movement, metrostaxis.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and metrorrhagia warp is many, blood leaking in gestation, frequent fetal movement; Hypertension.

The effect of the Radix Pulsatillae: the Radix Pulsatillae has the effect of heat-clearing and toxic substances removing, removing heat from blood, improving eyesight, killing parasites for relieving itching, the bitter temperature taste Radix Pulsatillae, master enters heart channel and kidney channel, and warm disease is gone mad for curing mainly, and the poly-abdominal mass of removing food stagnancy and disease.Goiter scrofula all can be fallen apart, and epistaxis incised wound also can be put down.Scrotal hernia fully recover from an illness partially swollen more, the tinea alba raw meat of having a strong smell is controlled and also can.Stomachache osteopathia Yantongzhi medicine for curing tooth-ache, red diarrhea can be clear by toxicity.Intestinal dirt extort may exhaust clean, assistant with wine, knowingly follow the example of a wrongdoer spirit.

The effect of Rhizoma Belamcandae: Rhizoma Belamcandae, perennial vertical herbage.Root stock is irregular bulk.Stem is upright, solid.Leaf sword shape, flat, alternate, embedding shape 2 row that change, style is cylindrical, and stigma 3 is shallow to be split, and ovary is the next, Room 3, axile placenta, ovule is most.Capsule obovate, yellow green, when ripe, 3 lobes split; Seed is spherical, and black purple is glossy, raw on the axis of fruit.For heat-clearing and detoxifying herb, cure mainly: control sore throat pharyngalgia, cough with dyspnea, accumulation and obstruction of sputum, scrofula tuberculosis, malaria with splenomegaly, women's amenorrhea, carbuncle sore tumefacting virus.

The effect of Radix Rehmanniae: the tuber that Radix Rehmanniae is scrophulariaceae rehmannia glutinosa plant.Have another name called ground marrow (< < herbal classic > >), Proterozoic (the just > > of < < book on Chinese herbal medicine), dry Radix Rehmanniae (< < Chinese medicinal herbal > >).Former plant Radix Rehmanniae has another name called: benzyl (the elegant > > of < <), glutinous rehmannia (< < does not record > >), Fructus Elaeagni Umbellatae (< < Amplification on Materia Medica > >), grandmother's milk (< < Herbal for Relief of Famines > >), Canis familiaris L. milk (< < Zhiwu Mingshi Tukao > >), mountain cigarette, Chinese cabbage, wine pot flower, sweet wine, honey jar.There is nourishing YIN and clearing away heat, promote the production of body fluid, the effect that removing heat from blood is enriched blood.

The effect of Fructus Psoraleae: another name: the fruit that Semen Allii Tuberosi, the solid fat of mother-in-law, Fructus Psoraleae, Psoralen sparrow hawk, FRUCTUS PSORALEAE, Hu Fructus Psoraleae, Ji Guzi, FRUCTUS PSORALEAE are legumes psoraleae recklessly, warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.For impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.

The effect of Radix Dipsaci: be the root of herbaceos perennial Radix Dipsaci, because energy " synthetism of continuous folding " is gained the name.Excavate autumn, removes root head and fibrous root, is dried to half-driedly with low baking temperature, banks up " diaphoresis " when the inner virescence, then dry.< < the southern regions of the Yunnan Province book on Chinese herbal medicine > >: " meridians determine in tonifying liver, bone and muscle strengthening, and only in warp, (muscles and bones) ached; antiabortive, controls married woman leucorrhea, tissue regeneration promoting blood, removing blood stasis with potent drugs blood; the stillborn fetus that falls, and the cough-relieving hemoptysis of coughing, controls red white turbid urine.

The effect of Moschus: the secretions of the umbilicus that Moschus is male Moschus moschiferous and the glandular sac between genitals, after being dried, be graininess or bulk, there is special fragrance, there is bitterness, can make spice, also can be used as medicine.Be central nervous excitation agent, external can be eased pain, promoting blood circulation and detumescence.

The effect of Radix Arnebiae (Radix Lithospermi): have another name called mountain Radix Arnebiae (Radix Lithospermi), Zi Dan, Radix Arnebiae (Radix Lithospermi), be distributed in the ground such as Liaoning, Shanxi, Hunan, Gansu, Shandong, Hubei, Guangxi, Sichuan, Shaanxi, Guizhou, Jiangxi, Hebei, Henan of Japan, Korea and China's Mainland, grow in the area of 50 meters to 2500 meters of height above sea level, be grown in patana more, started at present artificial introducing and planting.Be a kind of of Chinese herbal medicine, uproot spring and autumn, removes residual stem and earth (not washing with water, in case fade), dries or low baking temperature oven dry raw using.The root of Radix Arnebiae (Radix Lithospermi) and spending all containing pigment, Acetyl-shikonin Acetylshikonin, alkannan, isobutyryl shikonin etc., function cures mainly removing heat from blood, invigorates blood circulation, the rash of detoxifying.For heat in blood poison contain, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.Clearing away heat and cooling blood, for measles, calentura skin eruption, eczema, hematuria, stranguria with blood, dysentery, skin infection, erysipelas, burn, constipation with heat retention,

The effect of Herba Ecliptae: Compositae, annual herb plant.Uprightly, tool stolon; Leaf is to life, lanceolar; Head inflorescence, axil is raw or top is raw, floral white; Achene black.Be common in field stalk, Gou Xi limit wetland.Herb is medicinal, has the effect of convergence, hemostasis, invigorating the liver and kidney

Caulis Bambusae In Taenia is traditional Chinese medical science medical material, is the dry intermediate layer of the stem stalk of grass bambusa breviflora Munro, major part allusion quotation bamboo or phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle.All can gather and process the whole year, gets fresh stem, removes crust, slightly viridant intermediate layer spread to strand, or chip, and ties up bunchy, dries in the shade.The former claims " loose Caulis Bambusae In Taenia ", and the latter claims " neat Caulis Bambusae In Taenia ".Nature and flavor cold nature, sweet in the mouth.Function cures mainly: removing heat-phlegm, relieves restlessness and prevents vomiting.For phlegm-heat cough, gallbladder fire, hold expectorant, dysphoria with smothery sensation vomiting, palpitation with fear insomnia, wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement under the arm.

The effect of Borneolum Syntheticum: Borneolum Syntheticum, have another name called sheet brain, Fructus Citri tangerinae sheet, Borneolum Syntheticum, MEIHUA BINGPIAN, Dipterocarpus pilosus, Flos Mume brain, Borneolum Syntheticum brain, Mei Bing etc., the resin and the volatile oil processed goods that are Spore density Borneolum Syntheticum extract the crystallization obtaining, and are near pure dextro Borneolum Syntheticum.Also useful chemical method is synthetic.It can be used for for excess syndrome of stroke coma, for conjunctival congestion and swelling pain, sore throat aphtha, for skin infection, swells and ache, and does not hold back etc. after bursting.

The effect of Fructus Gardeniae: another name Yellow Fructus Gardeniae, Fructus Gardeniae, white toad are the fruits of Maguireothamnus speciosus Fructus Gardeniae.At present, the fruit of Fructus Gardeniae is Chinese medicine, has the effects such as hepatoprotective, function of gallbladder promoting, blood pressure lowering, calmness, hemostasis, detumescence.

The effect of Semen Coicis: Semen Coicis is the annual or perennial herb of grass family.To remove the kernel of shell and kind skin, be used as medicine.The provinces such as main product Hunan, Hebei, Jiangsu, Fujian.Sweet in the mouth, light, cold nature.There are invigorating spleen to remove dampness, clearing away heat and discharging pus function.For diseases such as diarrhea due to hypofunction of the spleen edema beriberi, leucorrhea, wet, arthralgia, acute appendicitis, consumptive lung diseases.Still for cancer and multiple warts such as gastric cancer, cervical cancer, chorionic epithelioma.

The effect of Caulis Akebiae: Caulis Akebiae is the woody stems of dicotyledon medicine Caulis Akebiae, section plant Caulis Akebiae or threeleaf akebia, five leaf Caulis Akebiaes.Nature and flavor are bitter, cool, pathogenic fire purging row water, promoting blood circulation.Cure mainly hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasis.

The effect of Semen Cuscutae: Semen Cuscutae is the special parasitic plant of a kind of physiological make-up, in the cell of its composition, there is no chloroplast, utilization is climbed rattan columnar structure and is sought connections with at other plant, and stretch out spine from contact host's position, protrude into the through phloem of host, draw nutrient to support one's family, further also can store into starch grain in tissue.Cuscuta chinensis is the seed of dicotyledon scammonia section plant Semen Cuscutae, southern Semen Cuscutae, cuscuta japonica Choisy etc., has the effect of the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, solid tire stopping leak.Externally treating leucoderma.

The effect of Herba Artemisiae Scopariae: Herba Artemisiae Scopariae is the dry aerial parts of Compositae herbaceos perennial Artemisia scoparia Waldst. et Kit. or Tarragon.The most area of China has distribution, the ground such as main product Shaanxi, Shanxi, Anhui.This product bitter in the mouth, pungent, be slightly cold, enter spleen, stomach, liver, gallbladder meridian.Effect clearing away damp-heat, jaundice eliminating subcutaneous ulcer.There is remarkable progress the aspects such as relevant this product pharmacological action and clinical practice in recent years, have function of gallbladder promoting, protect the liver; The effects such as resisting pathogenic microbes, antitumor, antipyretic-antalgic antiinflammatory.Also can treat intractable eczema.

The effect of siritch: siritch has long edible history in China.Siritch is extremely many in appellation among the people, has Wang oil, the Lushui River is oily and Oleum Sesami etc.Linum is one of China five large oil crop, is commonly called as Semen Sesami, sesame.Siritch also claims Oleum sesami, the fatty oil that Ta Shiconghu section plant sesame seed squeezes, the effect that has moistening dryness for relaxing bowels, nourishing blood to expel wind, weak, dizzy after can curing the disease, constipation, old man's xerosis cutis, Scaling, allergic dermatitis, pruritus, skin infection eczema and hypertension, sclerosis of blood vessels, cholesterol such as increase at the disease.

The present invention has designed, and is used for the treatment of the Chinese medicine composition of leukoplakia vulvae, includes: Chinese medicine composition I be set to by radix Sophorae Flavescentis28 grams, 72 grams of Radix Salviae Miltiorrhizaes, 25 grams of Cortex Phellodendris, 48 grams of Fructus Cnidiis, 62 grams of the Fructus Kochiae, 9 grams of Radix Angelicae Sinensis, 6.1 grams of the Radixs Astragali, 10 grams of Sanguis Draxonis, 15 grams of Herba Taxillis, 8.8 grams of the Radix Pulsatillaes, 35.5 grams of Rhizoma Belamcandae, 19 grams of Radix Rehmanniae, 37 grams of Fructus Psoraleaes, 21 grams of Radix Dipsaci, 32 grams, Moschus, 8 grams of Radix Arnebiae (Radix Lithospermi)s, 7.8 grams of Herba Ecliptaes, 14 grams of Caulis Bambusae In Taenia and 58 grams of compositions of Borneolum Syntheticum; Chinese medicine composition II is set to be comprised of in right amount 88 grams of Fructus Gardeniaes, 70 grams of Semen Coiciss, 45 grams of Caulis Akebiaes, 32 grams of Semen Cuscutae, 15 grams of Herba Artemisiae Scopariaes and siritch.

The present invention has designed, the boiling and to the device that diseased region atomization is processed, include steam chamber for assembling steam, the drug cartridge that is set to be communicated with steam chamber and to be set to distribute by row by row, be arranged on drug cartridge the permeable membrane for Chinese medicine and medicinal liquid are isolated of Chinese medicine composition that is used for the treatment of leukoplakia vulvae.

According to the not classification of Chinese medicine, Chinese medicine is put in different drug cartridge, be connected with steam chamber respectively again, pharmaceutical compositions is penetrated in water vapour, by permeable membrane, enter into drug cartridge bottom, owing to having designed steam chamber, drug cartridge and permeable membrane, according to different classes of Chinese medicine, in different drug cartridge, boil, no longer different classes of Chinese medicine is mixed and boiled, the composition that therefore extracts Chinese medicine is best.

The present invention has designed, also include valve and lower valve, on the lower end surface of steam chamber, be provided with connection, drug cartridge is set to connect with the connection of steam chamber and is provided with valve between the connection of steam chamber and drug cartridge, on the lower end surface of drug cartridge, be provided with lower valve, in drug cartridge, be provided with division board and be provided with permeable membrane on the division board of drug cartridge.

The present invention has designed, also include radiator, atomization ball, nozzle, plug and support, on support, be provided with and have in the seat cushion of cavity cavity that nozzle is arranged on seat cushion, in the lower end of seat cushion, be provided with atomization ball and atomization ball is set to support hinged, in atomization ball, be provided with buffering cavity and on atomization ball, be provided with the connector being communicated with the buffering cavity of atomization ball, connector at atomization ball is provided with nozzle and plug, the cushion chamber of atomization ball is set to be communicated with radiator, and radiator is set to be communicated with lower valve.

The present invention has designed, and drug cartridge is set to four and be set to arranged distribution on the lower end surface of steam chamber.

The present invention has designed, and is provided with spiral form road groove on the cushion chamber wall of atomization ball.

The present invention has designed, and permeable membrane is set to be carried as the one-way membrane of the pressure of 1.51～1.65Mpa.

The present invention has designed, and is provided with sealed opening on steam chamber.

Three, accompanying drawing explanation

Fig. 1 is the schematic diagram of boiling of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae of the present invention and device that diseased region atomization is processed.

Four, the specific embodiment

The ingredients of first embodiment of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae of the present invention, includes: Chinese medicine composition I be set to by radix Sophorae Flavescentis25 grams, 55 grams of Radix Salviae Miltiorrhizaes, 10 grams of Cortex Phellodendris, 35 grams of Fructus Cnidiis, 60 grams of the Fructus Kochiae, 7 grams of Radix Angelicae Sinensis, 6 grams of the Radixs Astragali, 10 grams of Sanguis Draxonis, 10 grams of Herba Taxillis, 5 grams of the Radix Pulsatillaes, 35 grams of Rhizoma Belamcandae, 10 grams of Radix Rehmanniae, 30 grams of Fructus Psoraleaes, 20 grams of Radix Dipsaci, 10 grams, Moschus, 5 grams of Radix Arnebiae (Radix Lithospermi)s, 6 grams of Herba Ecliptaes, 10 grams of Caulis Bambusae In Taenia and 50 grams of compositions of Borneolum Syntheticum; Chinese medicine composition II is set to be comprised of in right amount 80 grams of Fructus Gardeniaes, 50 grams of Semen Coiciss, 30 grams of Caulis Akebiaes, 25 grams of Semen Cuscutae, 10 grams of Herba Artemisiae Scopariaes and siritch.

These several Chinese medicine decoctings in Chinese medicine composition I are made to Chinese medicinal decoction, and every natural gift morning, noon and afternoon take for three times, within seven days, are a course for the treatment of, after the course for the treatment of, and drug withdrawal 3～5 days, then carry out next one course for the treatment of; Fructus Gardeniae in Chinese medicine composition II, Semen Coicis, Caulis Akebiae, Semen Cuscutae and Herba Artemisiae Scopariae are soaked more than 24 hours in siritch, be put in container and carry out steaming and decocting, make the steam producing act on pudendum position, white macula is carried out to atomization processing, at least two days once, and continuous is for seven times a course for the treatment of.

At Hospital Attached to Taishan Medical College, carried out the clinical observation of leukoplakia vulvae:

95 examples are all made a definite diagnosis through vulvar disease biopsy pathology; Maximum 66 years old of patient age, minimum 23 years old, 45.6 years old mean age; 3 years person's 50 examples of course of disease <, 3～10 years 35 examples, 10 years 10 examples of >.95 examples are divided into treatment group 60 examples and matched group 35 examples at random, and two groups of patients, at aspect there was no significant differences such as histological type, age, course of disease length, have comparability.

Therapeutic Method: treatment group adopts medicine of the present invention.Usage: 1 dose of Chinese medicine composition I decocting, every day, Chinese medicine composition II is carried out atomization processing after 10～15 minutes to white macula position, general every day 1 time.Matched group adopts urea compound ointment partial smearing, every day 2 times, all take 4 weeks as 1 course for the treatment of, treats altogether for 2 courses for the treatment of, outpatient service regular follow-up for 2 groups.

Efficacy assessment standard: short term effect criterion clinical cure: transference cure, the mucocutaneous color in vulvar disease district and elasticity are recovered normally substantially, after treatment finishes, follow up a case by regular visits to half a year without recurrence, and pathologic finding is normal skin mucosa; Effective: transference cure, skin elasticity is obviously improved, and color significantly changes, and follows up a case by regular visits to half a year without recurrence, and the mucocutaneous organizational structure of pathologic finding recovers normal substantially; Take a turn for the better: symptom alleviates, and skin elasticity and color have improvement to a certain degree, and diseased region dwindles, it is normal that pathologic finding skin histology structure division recovers; Invalid: after treatment, symptom is without improvement, and skin of vulva is without change, and the mucocutaneous organizational structure of pathologic finding is unchanged.

Pruritus standards of grading 0 minute: there is no pruritus: 1 minute: have the property a crossed pruritus; 2 minutes: have pruritus, but do not affect sleep; 3 minutes: have serious pruritus, impact sleep.

In short term effect treatment group 60 examples, cure 15 examples, effective 33 examples, 10 examples that take a turn for the better, invalid 2 examples, total effective rate 96.66%; In matched group 35 examples, 17 examples that take a turn for the better, invalid 18 examples, total effective rate 48.57%.2 groups of total effective rate comparisons, have significant difference ( p<0.05), treatment group short term effect is obviously better than matched group.

Before treatment, patient is distributed as: 0 minute: treatment group 2 examples, matched group 0 example; 1 minute: treatment group 10 examples, matched group 8 examples; 2 minutes: treatment group 20 examples, matched group 17 examples; 3 minutes: treatment group 28 examples, matched group 20 examples; After treatment, patient is distributed as: 0 minute: treatment group 10 examples, matched group 0 example; 1 minute: treatment group 43 examples, matched group 15 examples; 2 minutes: treatment group 5 examples, matched group 8 examples; 3 minutes: treatment group 2 examples, matched group 12 examples.

Before and after treatment, pruritus scoring is learned and is processed by statistics, after treatment treatment group and matched group pruritus mark (within 0+1 minute, number of cases accounts for the ratio of respectively organizing number of cases) relatively have significant difference ( p< 0.05), the pruritus improvement for the treatment of group is obviously better than matched group.

Model case

1, Lee XX, female, 9 years old, in August, 2010 was medical, and main suit's pudendum is very itched, and because scratch, there is scratch, the redness of many places in pudendum road, and nympha has ulcer 2 weeks, through the outbreak repeatedly again in 3 days for the treatment of urea compound Ointment in Treatment.Pathologic finding turns out to be leukoplakia vulvae.Patient requires to take oral medicinal herb of the present invention and atomization is processed, and every dose of two courses for the treatment of of 1/3 amount treatment of getting adult, clinical symptoms disappears completely, does not follow up a case by regular visits to half a year and does not recur.

2, king X, female, 50 years old, medical in July, 2011, pruritus vulvae, can have scorching hot, pain 10 days sometimes, and pudendum cleans 5 days poor effect with Ph4 weak acid formula feminine care liquid.Have a medical check-up: pudendum day shift and scratching.Pathologic finding is made a definite diagnosis this disease.Patient requires to take oral medicinal herb medicine of the present invention and two courses for the treatment of are processed in atomization, and clinical symptoms disappears completely, within 1 year, does not follow up a case by regular visits to and does not recur.

3, Wei XX, female, 59 years old, medical in JIUYUE, 2012, pruritus vulvae, sometimes scorching hot, pars affecta skin is coarse, have scratch, the first quarter moon of chapping, smears fluocinonide ointment and treats 1 week poor effect in local commune hospital.Pathologic finding turns out to be leukoplakia vulvae.Patient requires to take oral medicinal herb medicine of the present invention and four courses for the treatment of are processed in atomization, and clinical symptoms disappears completely, does not follow up a case by regular visits to half a year and does not recur.

The ingredients of second embodiment of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae of the present invention, includes: Chinese medicine composition I be set to by radix Sophorae Flavescentis45 grams, 75 grams of Radix Salviae Miltiorrhizaes, 35 grams of Cortex Phellodendris, 50 grams of Fructus Cnidiis, 75 grams of the Fructus Kochiae, 9 grams of Radix Angelicae Sinensis, 8 grams of the Radixs Astragali, 15 grams of Sanguis Draxonis, 15 grams of Herba Taxillis, 9 grams of the Radix Pulsatillaes, 40 grams of Rhizoma Belamcandae, 20 grams of Radix Rehmanniae, 40 grams of Fructus Psoraleaes, 25 grams of Radix Dipsaci, 35 grams, Moschus, 8 grams of Radix Arnebiae (Radix Lithospermi)s, 9 grams of Herba Ecliptaes, 15 grams of Caulis Bambusae In Taenia and 70 grams of compositions of Borneolum Syntheticum; Chinese medicine composition II is set to be comprised of in right amount 90 grams of Fructus Gardeniaes, 70 grams of Semen Coiciss, 45 grams of Caulis Akebiaes, 45 grams of Semen Cuscutae, 20 grams of Herba Artemisiae Scopariaes and siritch.

The ingredients of the 3rd embodiment of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae of the present invention, includes: Chinese medicine composition I be set to by radix Sophorae Flavescentis35 grams, 65 grams of Radix Salviae Miltiorrhizaes, 22.5 grams of Cortex Phellodendris, 42.5 grams of Fructus Cnidiis, 67.5 grams of the Fructus Kochiae, 8 grams of Radix Angelicae Sinensis, 8 grams of the Radixs Astragali, 12.5 grams of Sanguis Draxonis, 12.5 grams of Herba Taxillis, 7 grams of the Radix Pulsatillaes, 37.5 grams of Rhizoma Belamcandae, 15 grams of Radix Rehmanniae, 35 grams of Fructus Psoraleaes, 22.5 grams of Radix Dipsaci, 17.5 grams, Moschus, 6.5 grams of Radix Arnebiae (Radix Lithospermi)s, 7.5 grams of Herba Ecliptaes, 12.5 grams of Caulis Bambusae In Taenia and 60 grams of compositions of Borneolum Syntheticum; Chinese medicine composition II is set to be comprised of in right amount 85 grams of Fructus Gardeniaes, 60 grams of Semen Coiciss, 37.5 grams of Caulis Akebiaes, 35 grams of Semen Cuscutae, 15 grams of Herba Artemisiae Scopariaes and siritch.

The ingredients of the 4th embodiment of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae of the present invention, includes: Chinese medicine composition I be set to by radix Sophorae Flavescentis28 grams, 72 grams of Radix Salviae Miltiorrhizaes, 25 grams of Cortex Phellodendris, 48 grams of Fructus Cnidiis, 62 grams of the Fructus Kochiae, 9 grams of Radix Angelicae Sinensis, 6.1 grams of the Radixs Astragali, 10 grams of Sanguis Draxonis, 15 grams of Herba Taxillis, 8.8 grams of the Radix Pulsatillaes, 35.5 grams of Rhizoma Belamcandae, 19 grams of Radix Rehmanniae, 37 grams of Fructus Psoraleaes, 21 grams of Radix Dipsaci, 32 grams, Moschus, 8 grams of Radix Arnebiae (Radix Lithospermi)s, 7.8 grams of Herba Ecliptaes, 14 grams of Caulis Bambusae In Taenia and 58 grams of compositions of Borneolum Syntheticum; Chinese medicine composition II is set to be comprised of in right amount 88 grams of Fructus Gardeniaes, 70 grams of Semen Coiciss, 45 grams of Caulis Akebiaes, 32 grams of Semen Cuscutae, 15 grams of Herba Artemisiae Scopariaes and siritch.The present embodiment is best at the therapeutic effect in 20-30 year to patient age, and effective percentage is 99%, cure rate is 95%.

Therefore the present invention is theoretical according to traditional Chinese medical science traditional theory and modern treatment, theoretical in conjunction with traditional Chinese medical science traditional theory and modern treatment, the better effects if for the treatment of leukoplakia vulvae.

First embodiment of the device that boils and diseased region atomization is processed that is used for the treatment of the Chinese medicine composition of leukoplakia vulvae, include steam chamber 1, drug cartridge 2, upper valve 3, permeable membrane 4, lower valve 5, radiator 6, atomization ball 7, nozzle 8, plug 9 and support 10, on the lower end surface of steam chamber 1, be provided with connection, drug cartridge 2 is set to connect with the connection of steam chamber 1 and is provided with valve 3 between the connection of steam chamber 1 and drug cartridge 2, on the lower end surface of drug cartridge 2, be provided with lower valve 5, in drug cartridge 2, be provided with division board and on the division board of drug cartridge 2, be provided with permeable membrane 4, on support 10, being provided with seat cushion the nozzle 8 with cavity is arranged in the cavity of seat cushion, in the lower end of seat cushion, being provided with atomization ball 7 atomization ball 7 is set to support 10 hinged, in atomization ball 7, be provided with buffering cavity and on atomization ball 7, be provided with the connector being communicated with the buffering cavity of atomization ball 7, connector at atomization ball 7 is provided with nozzle 8 and plug 9, the cushion chamber of atomization ball 7 is set to be communicated with radiator 6, radiator 6 is set to be communicated with lower valve 5.

In the present embodiment, drug cartridge 2 is set to four and be set to arranged distribution on the lower end surface of steam chamber 1.

In the present embodiment, on the cushion chamber wall of atomization ball 7, be provided with spiral form road groove.

In the present embodiment, permeable membrane 4 is set to be carried as the one-way membrane of the pressure of 1.51Mpa.

In the present embodiment, on steam chamber 1, be provided with sealed opening.

According to the not classification of Chinese medicine, Chinese medicine is put in different drug cartridge 2, be connected with steam chamber 1 respectively again, regulate the open amount of the upper valve 3 in different drug cartridge 2, make to bear in different drug cartridge 2 water vapour of different pressures, thereby make different Chinese medicines in the water vapour of different pressures and temperature, pharmaceutical compositions is penetrated in water vapour, by permeable membrane 4, enter into drug cartridge 2 bottoms, by lower valve 5, access medicinal liquid and take orally; Equally, according to the not classification of Chinese medicine, Chinese medicine is put in different drug cartridge 2, then is connected with steam chamber 1 respectively, regulate the open amount of the upper valve 3 in different drug cartridge 2, make to enter in radiator 6 by lower valve 5 with the steam of pharmaceutical compositions, in radiator 6, after cooling, enter into atomization ball 7, according to patient's situation, the nozzle 8 of varying number is installed, patient is sitting on support 10, nozzle 8 is aimed to leukoplakia vulvae and carry out atomization processing.

Second embodiment of the device that boils and diseased region atomization is processed that is used for the treatment of the Chinese medicine composition of leukoplakia vulvae, permeable membrane 4 is set to be carried as the one-way membrane of the pressure of 1.65Mpa.

The 3rd embodiment of the device that boils and diseased region atomization is processed that is used for the treatment of the Chinese medicine composition of leukoplakia vulvae, permeable membrane 4 is set to be carried as the one-way membrane of the pressure of 1.58Mpa.

The 4th embodiment of the device that boils and diseased region atomization is processed that is used for the treatment of the Chinese medicine composition of leukoplakia vulvae, permeable membrane 4 is set to be carried as the one-way membrane of the pressure of 1.52Mpa.

The 5th embodiment of the device that boils and diseased region atomization is processed that is used for the treatment of the Chinese medicine composition of leukoplakia vulvae, permeable membrane 4 is set to be carried as the one-way membrane of the pressure of 1.62Mpa.

Above-described embodiment is a kind of way of realization of the device that is used for the treatment of the Chinese medicine composition of leukoplakia vulvae and boils and diseased region atomization is processed provided by the present invention; according to other distortion of scheme provided by the present invention; increase or reduce composition or step wherein; or the technical field approaching with the present invention by the present invention for other, all belongs to protection scope of the present invention.

Claims (9)

1. a Chinese medicine composition that is used for the treatment of leukoplakia vulvae, is characterized in that: include: Chinese medicine composition I is set to be comprised of Radix Sophorae Flavescentis 25-45 gram, Radix Salviae Miltiorrhizae 55-75 gram, Cortex Phellodendri 10-35 gram, Fructus Cnidii 35-50 gram, Fructus Kochiae 60-75 gram, Radix Angelicae Sinensis 7-9 gram, Radix Astragali 6-8 gram, Sanguis Draxonis 10-15 gram, Herba Taxilli 10-15 gram, Radix Pulsatillae 5-9 gram, Rhizoma Belamcandae 35-40 gram, Radix Rehmanniae 10-20 gram, Fructus Psoraleae 30-40 gram, Radix Dipsaci 20-25 gram, Moschus 10-35 gram, Radix Arnebiae (Radix Lithospermi) 5-8 gram, Herba Ecliptae 6-9 gram, Caulis Bambusae In Taenia 10-15 gram and Borneolum Syntheticum 50-70 gram; Chinese medicine composition II is set to be comprised of in right amount Fructus Gardeniae 80-90 gram, Semen Coicis 50-70 gram, Caulis Akebiae 30-45 gram, Semen Cuscutae 25-45 gram, Herba Artemisiae Scopariae 10-20 gram and siritch.

2. the Chinese medicine composition that is used for the treatment of leukoplakia vulvae according to claim 1; It is characterized in that: include: Chinese medicine composition I be set to by radix Sophorae Flavescentis28 grams, 72 grams of Radix Salviae Miltiorrhizaes, 25 grams of Cortex Phellodendris, 48 grams of Fructus Cnidiis, 62 grams of the Fructus Kochiae, 9 grams of Radix Angelicae Sinensis, 6.1 grams of the Radixs Astragali, 10 grams of Sanguis Draxonis, 15 grams of Herba Taxillis, 8.8 grams of the Radix Pulsatillaes, 35.5 grams of Rhizoma Belamcandae, 19 grams of Radix Rehmanniae, 37 grams of Fructus Psoraleaes, 21 grams of Radix Dipsaci, 32 grams, Moschus, 8 grams of Radix Arnebiae (Radix Lithospermi)s, 7.8 grams of Herba Ecliptaes, 14 grams of Caulis Bambusae In Taenia and 58 grams of compositions of Borneolum Syntheticum; Chinese medicine composition II is set to be comprised of in right amount 88 grams of Fructus Gardeniaes, 70 grams of Semen Coiciss, 45 grams of Caulis Akebiaes, 32 grams of Semen Cuscutae, 15 grams of Herba Artemisiae Scopariaes and siritch.

3. the device that boils and diseased region atomization is processed of a Chinese medicine composition that is used for the treatment of leukoplakia vulvae; It is characterized in that: the drug cartridge (2) that include steam chamber (1) for assembling steam, is set to be communicated with steam chamber (1) and to be set to distribute by row by row, be arranged on drug cartridge (2) the permeable membrane (4) for Chinese medicine and medicinal liquid are isolated.

4. the device that boils and diseased region atomization is processed of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae according to claim 3; It is characterized in that: also include valve (3) and lower valve (5), on the lower end surface of steam chamber (1), be provided with connection, drug cartridge (2) is set to connect with the connection of steam chamber (1) and is provided with upper valve (3) between the connection of steam chamber (1) and drug cartridge (2), on the lower end surface of drug cartridge (2), be provided with lower valve (5), in drug cartridge (2), be provided with division board and on the division board of drug cartridge (2), be provided with permeable membrane (4).

5. the device that boils and diseased region atomization is processed of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae according to claim 4, it is characterized in that: also include radiator (6), atomization ball (7), nozzle (8), plug (9) and support (10), on support (10), being provided with seat cushion the nozzle (8) with cavity is arranged in the cavity of seat cushion, in the lower end of seat cushion, be provided with atomization ball (7) and atomization ball (7) is set to support (10) hinged, in atomization ball (7), be provided with buffering cavity and on atomization ball (7), be provided with the connector being communicated with the buffering cavity of atomization ball (7), connector at atomization ball (7) is provided with nozzle (8) and plug (9), the cushion chamber of atomization ball (7) is set to be communicated with radiator (6), radiator (6) is set to be communicated with lower valve (5).

6. the device that boils and diseased region atomization is processed of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae according to claim 4; It is characterized in that: drug cartridge (2) is set to four and be set to arranged distribution on the lower end surface of steam chamber (1).

7. the device that boils and diseased region atomization is processed of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae according to claim 4; It is characterized in that: on the cushion chamber wall of atomization ball (7), be provided with spiral form road groove.

8. the device that boils and diseased region atomization is processed of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae according to claim 4; It is characterized in that: permeable membrane (4) is set to be carried as the one-way membrane of the pressure of 1.51-1.65Mpa.

9. the device that boils and diseased region atomization is processed of the Chinese medicine composition that is used for the treatment of leukoplakia vulvae according to claim 4; It is characterized in that: on steam chamber (1), be provided with sealed opening.

Images