CN103520844A - Focused ultrasonic treating device - Google Patents
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- CN103520844A CN103520844A CN201210227513.7A CN201210227513A CN103520844A CN 103520844 A CN103520844 A CN 103520844A CN 201210227513 A CN201210227513 A CN 201210227513A CN 103520844 A CN103520844 A CN 103520844A
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Abstract
The present invention provides a focused ultrasonic treating device which belongs to the technical field of a medical device. The focused ultrasonic treating device of the invention can settle the following problems in the existing in-vitro focused ultrasonic treating technique: low clarity in imaging, high difficulty in accurately positioning a focus, and low treating effect. The focused ultrasonic treating device of the invention comprises the following components: an ultrasonic medium accommodating unit which accommodates an ultrasonic wave conducting medium; an ultrasonic transducer which is arranged in the ultrasonic medium accommodating unit and can conduct the ultrasonic wave to the body of a patient; a motion mechanism which drives the ultrasonic transducer to move in the ultrasonic medium accommodating unit; an ultrasonic transducer bracket which is connected with the motion mechanism, wherein the ultrasonic transducer is connected with the transducer bracket; a positioning monitoring system which is used for forming the image of a to-be-treated part of the patient and is provided with a chamber for accommodating the ultrasonic medium accommodating unit and the to-be-treated part of the patient in treatment; and a treatment bed which is used for fixing the position of the patient and is at least arranged in the chamber partially. The focused ultrasonic treating device of the invention can be used for treating disease, such as prostatosis.
Description
Technical field
The invention belongs to technical field of medical instruments, be specifically related to a kind of focused ultrasound therapy device, especially prostatosis focused ultrasound therapy device.
Background technology
Focused ultrasound therapy technology is a kind of technology of utilizing ultrasonic therapy disease, it sends the ultrasound wave of focusing to lesions position by ultrasonic transducer, utilize hyperacoustic effect to treat target area focus, as diseases such as treatment prostatitis, tumor, cervical erosion, cyclomastopathy.Focused ultrasound therapy technology belongs to the treatment technology of atraumatic, therefore have low, painful little, the few side effects of cost, almost without complication, recover fast, can repetitive therapy etc. advantage.Meanwhile, for other routine treatment of numerous disease, all can not reach the effect of focused ultrasound therapy.For example, prostatosis is one of modal disease of adult male, particularly prostatic hyperplasia, and data shows, the sickness rate of various countries' adult male prostatic hyperplasia is respectively: France 14.2%, England 20.4%, Canada 23.0%, Scotland 25.3%, Spain 30.4%, the U.S. 33.7%; And in China, in the time of more than the sickness rate of 40 to 79 years old age bracket prostatic hyperplasia is about 50%, 80 years old, sickness rate is up to 80%.Because prostate outer wrapping the tough and tensile adipose membrane of one deck, drug molecule is difficult to infiltrate, so the time of Drug therapy prostatosis is long, poor effect; Operative treatment conventionally exist damage large, hemorrhage many, recover slow, excise the shortcomings such as body of gland size is limited, not reproducible.And because ultrasound wave can see through the adipose membrane that prostate increases easily, can not cause wound to human body again, so focused ultrasound therapy prostatosis has good prospect simultaneously.
For ultrasound wave is focused on to lesions position, focused ultrasound therapy technology is mainly divided into two kinds of intracavitary therapy and external treatments.Intracavitary therapy technology is that ultrasonic therapeutic head is stretched in human body and to lesions position and sent hyperacoustic treatment technology by urethra, rectum etc.; For example, patent documentation CN200510115582.9, CN200510093457.2, US5676692, US6371903, US5762066, EP0552995, WO00/24328 etc. have introduced the correlation technique of intracavity focused ultrasound therapy prostatosis.Wherein, " ultrasonic therapeutic head " comprises ultrasonic transducer and is enclosed within shell outside ultrasonic transducer etc., be filled with for conducting hyperacoustic ultrasound wave transmitting medium (as de aerated water) between shell and ultrasonic transducer.But, intracavitary therapy Technology Need stretches into human body by ultrasonic therapeutic head, due to the space in human body very limited (especially true for urethra etc.), therefore the volume of its ultrasonic therapeutic head (ultrasonic transducer), quantity, position etc. are all very limited, little and the difficult adjustment of focal length of ultrasonic power, doctor's operating difficulties, therapeutic domain is limited, patient's comfortableness is poor, easily causes infection and the damage of urethra, rectum etc.
External treatment technology is that the lesions position in the export-oriented body of human body sends hyperacoustic technology with ultrasonic therapeutic head.Patent documentation CN200920296822.3, US5443069 etc. have introduced the technology with the external focusing ultrasonic therapeutic prostatosis of ultra sonic imaging (B ultrasonic) technology guiding.Owing to ultrasonic therapeutic head need not being stretched in human body, not limited by cavity space, therefore external treatment technology is more easy to operate, patient's comfortableness is good, and can use the ultrasonic therapeutic head of large (its power and energy are also larger thus, and therapeutic effect is better) of emission area.But, existing external treatment technology all guides by B ultrasonic, and imaging definition of B ultrasonic, precision etc. are compared low with nuclear magnetic resonance (MRI), electronic computer x-ray tomography imaging (CT) etc., especially for the disease of the specific positions such as prostate, the imaging capability of B ultrasonic is poorer, be difficult to clear demonstration prostate and surrounding tissue thereof, thereby cause it can not accurately locate focus and show treatment situation, affect the therapeutic effect of external treatment.The magnetic resonance imaging system that imaging capability is stronger, electronic computer x-ray tomography imaging system etc. all has the cavity that can hold patient body, needs of patients recumbency could carry out imaging to diseased region after entering cavity, but because this void space is very limited, therefore when patient is in cavity, to handle again simultaneously ultrasonic therapeutic head it is treated just very inconvenient, therefore, in existing external treatment technology, can not use magnetic resonance imaging system, electronic computer x-ray tomography imaging system etc. has the locating and monitoring system of cavity, therefore just be there is to this problem in the treatment such as prostatosis etc.
Summary of the invention
Technical problem to be solved by this invention comprises, for existing intracavity focused ultrasound therapy technology can not use high power altrasonic transducer, operation inconvenience, that patient treatment is experienced is poor, easily cause infection, and external focusing ultrasonic therapeutic technology can not use have locating and monitoring system, the imaging of cavity unclear, be difficult to accurately to locate focus, problem that therapeutic effect is not good enough, provide a kind of can blur-free imaging, external focusing apparatus for ultrasonic therapeutic treatment that therapeutic effect is good.
The technical scheme that solution the technology of the present invention problem adopts is a kind of focused ultrasound therapy device, and it comprises:
For holding the ultrasonic medium accommodating unit of ultrasound wave transmitting medium;
At least one is positioned at the ultrasonic transducer of described ultrasonic medium accommodating unit, for sending concentration ultrasonic, during treatment described in the ultrasound wave conduction that ultrasonic transducer can be sent of ultrasound wave transmitting medium to patient body;
Be used for the motion that drives described ultrasonic transducer to move and change its focal position in ultrasonic medium accommodating unit;
With the transducer mount that described motion is connected, described ultrasonic transducer is connected on transducer mount;
For at least forming the locating and monitoring system of the image at patient position to be treated, it has can hold the cavity at described ultrasonic medium accommodating unit and patient position to be treated when treatment;
For the therapeutic bed of immobilized patients position, during treatment described in therapeutic bed be positioned at least partly the cavity of described monitoring system.
Wherein, ultrasound wave transmitting medium can be de aerated water, also can be other liquid.
Focused ultrasound therapy device of the present invention belongs to external focusing apparatus for ultrasonic therapeutic treatment, thus its have advantages of can use high power altrasonic transducer, easy to operate, patient treatment is experienced, be difficult for causing infection; Simultaneously, the ultrasonic medium accommodating unit and the therapeutic bed that wherein have again in the cavity that can stretch into locating and monitoring system are (obvious, ultrasonic transducer in ultrasonic medium accommodating unit also can stretch in cavity), ultrasonic transducer is connected with motion by transducer mount, therefore motion can (or part is outside cavity) drive ultrasonic transducer outside cavity, thereby it is not subject to the restriction of sky cavity space; Therefore, in focused ultrasound therapy device of the present invention, can use magnetic resonance imaging system or electronic computer x-ray tomography imaging system etc. to there is the locating and monitoring system of cavity, thereby its imaging clearly, can clearly locate pathological changes and show treatment situation, and therapeutic effect is good.
Preferably, described focused ultrasound therapy device is prostatosis focused ultrasound therapy device, and wherein said therapeutic bed is for being fixed patient's the sleeping position of lying on the back or lie prone.
Further preferably, described ultrasonic transducer is that circular arc is planar, the part that described arc surface is sphere.
Further preferably, described ultrasonic transducer is one, and this ultrasonic transducer is located at patient body front side, in patient's height direction in patient's abdominal region, and towards patient's prostatic; Or this ultrasonic transducer is located at patient body rear side, in patient's height direction in patient's buttocks position, and towards patient's prostatic.
The diameter of the sphere that further preferably, described ultrasonic transducer is corresponding is between 350 millimeters to 650 millimeters; Be parallel to patient's height direction and passing through in the plane of ultrasonic transducer focus, central angle corresponding to described ultrasonic transducer is between 20 degree to 120 degree, be parallel to patient body width and by the plane of ultrasonic transducer focus, central angle corresponding to described ultrasonic transducer is between 15 degree to 60 degree.
Further preferably, when described ultrasonic transducer is located at patient body top, patient body top is also located in described ultrasonic medium accommodating unit, and the lower ending opening of described ultrasonic medium accommodating unit, and described opening is sealed by the sound passing membrane that can contact with patient body; Or when described ultrasonic transducer is located at patient body below, described therapeutic bed is provided with the holding part of depression, described ultrasonic medium accommodating unit is located in described holding part, and upper end open.
Further preferably, described ultrasonic transducer is two, and be connected on a transducer mount, the focus of two ultrasonic transducers overlaps, and the equal diameters of corresponding sphere, wherein: a ultrasonic transducer is located at patient body front side, in patient's height direction in patient's abdominal region, and towards patient's prostatic; Another ultrasonic transducer is located at patient body rear side, in patient's height direction in patient's buttocks position, and towards patient's prostatic.
Further preferably, two described ultrasonic transducers are symmetrical arranged with respect to their focus.
The diameter of the sphere that further preferably, described ultrasonic transducer is corresponding is between 350 millimeters to 650 millimeters; Be parallel to patient's height direction and passing through in the plane of ultrasonic transducer focus, central angle corresponding to described ultrasonic transducer is between 20 degree to 120 degree, be parallel to patient body width and by the plane of ultrasonic transducer focus, central angle corresponding to described ultrasonic transducer is between 15 degree to 60 degree.
Further preferably, described therapeutic bed is provided with the holding part of depression, and the bottom of described ultrasonic medium accommodating unit is positioned at described holding part; On described ultrasonic medium accommodating unit, there are two openings that pass through for patient's shank, each opening is all connected with one end of a leg seal cover, and the other end of described leg seal cover has can be for patient's shank by also forming the hermetically-sealed construction that water-stop contact with patient's shank; On described ultrasonic medium accommodating unit, there is an opening passing through for patient's abdominal part, this opening is connected with one end of abdominal part sealing shroud, and the other end of described abdominal part sealing shroud has can be for patient's abdominal part by also forming the hermetically-sealed construction that water-stop contact with patient's abdominal part.
Further preferably, described ultrasonic medium accommodating unit has two, lay respectively at the above and below of patient body, two ultrasonic transducers lay respectively in two ultrasonic medium accommodating unit, wherein: be positioned at the ultrasonic medium accommodating unit lower ending opening of patient body top, and described opening is sealed by the sound passing membrane that can contact with patient body; Described therapeutic bed is provided with the holding part of depression, described in be arranged in patient body below ultrasonic medium accommodating unit be located at described holding part, and upper end open.
Preferably, described ultrasonic transducer is that circular arc is planar, the part that described arc surface is sphere.
Further preferably, described ultrasonic transducer has one; Or described ultrasonic transducer has at least two, the focus of each ultrasonic transducer overlaps, and the equal diameters of sphere corresponding to each ultrasonic transducer.
Further preferably, described ultrasonic transducer has at least two, and all ultrasonic transducers are connected on a transducer mount.
Preferably, described ultrasonic medium accommodating unit is provided with the opening for passing through for patient body, opening is connected with one end of sealing shroud, and the other end of described sealing shroud has can be for patient body by also forming the hermetically-sealed construction that water-stop contact with the patient body passing through.
Preferably, described ultrasonic medium accommodating unit is in the direction upper shed towards patient body, and described opening is sealed by the sound passing membrane that can contact with patient body.
Preferably, described therapeutic bed is provided with the holding part of depression, and described ultrasonic medium accommodating unit is arranged in described holding part, and described ultrasonic medium accommodating unit upper end open.Preferably, described locating and monitoring system is magnetic resonance imaging system or electronic computer x-ray tomography imaging system.
The present invention, for the ultrasonic therapy disease to focus on, is particularly suited for treating prostatosis; Certainly, the present invention also can be used for treating other pathological changes in pelvic cavity, abdominal cavity, thoracic cavity, as hepatopathy, nephropathy, pancreatic diseases, pneumonopathy etc.
Accompanying drawing explanation
Fig. 1 is the side-looking structural representation of the focused ultrasound therapy device of the embodiment of the present invention 2;
Fig. 2 is the plan structure schematic diagram (not shown patient and locating and monitoring system) of the focused ultrasound therapy device of the embodiment of the present invention 2;
Fig. 3 is that the focused ultrasound therapy device of the embodiment of the present invention 2 is along the sectional structure schematic diagram of AA face;
Fig. 4 is that the focused ultrasound therapy device of the embodiment of the present invention 2 is along the sectional structure schematic diagram (not shown patient and locating and monitoring system) of BB face;
Fig. 5 is the local structure for amplifying schematic diagram of I part of Fig. 4 of the focused ultrasound therapy device of the embodiment of the present invention 2;
Fig. 6 is a kind of structural representation of ultrasonic transducer of the focused ultrasound therapy device of the embodiment of the present invention 2;
Fig. 7 is a kind of sectional structure schematic diagram along its length of ultrasonic transducer of the focused ultrasound therapy device of the embodiment of the present invention 2;
Fig. 8 is a kind of sectional structure schematic diagram along its width of ultrasonic transducer of the focused ultrasound therapy device of the embodiment of the present invention 2;
Fig. 9 is the structural representation of another kind of ultrasonic transducer of the focused ultrasound therapy device of the embodiment of the present invention 2;
Figure 10 is the sectional structure schematic diagram of the focused ultrasound therapy device of the embodiment of the present invention 3;
Figure 11 is the sectional structure schematic diagram of the focused ultrasound therapy device of the embodiment of the present invention 4;
Figure 12 is the sectional structure schematic diagram of the focused ultrasound therapy device of the embodiment of the present invention 5.
Wherein Reference numeral is: 1, therapeutic bed; 3, protuberance; 4, ultrasonic medium accommodating unit; 5, locating and monitoring system; 6, abdominal part sealing shroud; 7, leg seal cover; 8, corrugated flexible hose; 10, ultrasonic transducer; 11, transducer mount; 12, the first driving-belt; 13, contact roller; 14, the first belt wheel; 15, the first electric rotating machine; 16, rotating shaft; 17, O RunddichtringO; 18, gear; 19, gear; 20, the second electric rotating machine; 21, rotating shaft carrying position; 22, the second driving-belt; 23, the 3rd belt wheel; 24, the second belt wheel; 25, the 3rd electric rotating machine; 26, guide rail; 27, O RunddichtringO; 28, annular seal space; 29, projection; 30, arc guide groove; 33, focus; 38, patient; 44, ultrasound wave passage; 45, sound passing membrane; 51, cavity.
The specific embodiment
For making those skilled in the art understand better technical scheme of the present invention, below in conjunction with the drawings and specific embodiments, the present invention is described in further detail.
Embodiment 1:
The present embodiment provides a kind of focused ultrasound therapy device, and it comprises:
For holding the ultrasonic medium accommodating unit of ultrasound wave transmitting medium;
At least one is positioned at the ultrasonic transducer of ultrasonic medium accommodating unit, and for sending concentration ultrasonic, the ultrasound wave conduction that during treatment, ultrasound wave transmitting medium can send ultrasonic transducer is to patient body;
Be used for the motion that drives ultrasonic transducer to move and change its focal position in ultrasonic medium accommodating unit;
The transducer mount being connected with motion, ultrasonic transducer is connected on transducer mount;
For at least forming the locating and monitoring system of the image at patient position to be treated, it has can hold the cavity at ultrasonic medium accommodating unit and patient position to be treated when treatment;
For the therapeutic bed of immobilized patients position, during treatment, therapeutic bed is positioned at the cavity of monitoring system at least partly.
The focused ultrasound therapy device of the present embodiment belongs to external focusing apparatus for ultrasonic therapeutic treatment, thus its have advantages of can use high power altrasonic transducer, easy to operate, patient treatment is experienced, be difficult for causing infection; Simultaneously, the ultrasonic medium accommodating unit and the therapeutic bed that wherein have again in the cavity that can stretch into locating and monitoring system are (obvious, ultrasonic transducer in ultrasonic medium accommodating unit also can stretch in cavity), ultrasonic transducer is connected with motion by transducer mount, therefore motion can (or part is outside cavity) drive ultrasonic transducer outside cavity, thereby it is not subject to the restriction of sky cavity space; Therefore, in the focused ultrasound therapy device of the present embodiment, can use magnetic resonance imaging system or electronic computer x-ray tomography imaging system etc. to there is the locating and monitoring system of cavity, thereby its imaging clearly, can clearly locate pathological changes and show treatment situation, and therapeutic effect is good.
Embodiment 2:
The present embodiment provides a kind of prostatosis focused ultrasound therapy device, and as shown in Figures 1 to 9, it comprises therapeutic bed 1, ultrasonic medium accommodating unit 4, ultrasonic transducer 10, motion, locating and monitoring system 5, transducer mount 11.
Wherein, locating and monitoring system 5 has cavity 51, and this cavity 51 is generally near cylindrical, and locating and monitoring system 5 can carry out Imaging for Monitoring to being positioned at the object of cavity 51.When treating, ultrasonic medium accommodating unit 4 and patient's 39 position to be treated is all arranged in cavity 51 (certainly, the ultrasonic transducer 10 in ultrasonic medium accommodating unit 4 is also arranged in cavity 51).Preferably, locating and monitoring system 5 is nuclear magnetic resonance (MRI) system or electronic computer x-ray tomography imaging (CT) system, during treatment, ultrasonic medium accommodating unit 4 is positioned at the image scanning scope of locating and monitoring system 5, therefore ultrasonic medium accommodating unit 4 preferably adopts plastic material; Because above-mentioned two kinds of imaging techniques all utilize electromagnetic wave to carry out, and metallics has shielding action to electromagnetic wave, therefore ultrasonic medium accommodating unit 4 preferably adopts plastic material (ultrasonic transducer 10, transducer mount 11 preferably also adopt non-metallic material certainly).The imaging clearly of magnetic resonance imaging system or electronic computer x-ray tomography imaging system is stablized, resolution is high, thus can accurately locate focus and observe focus situation, thus better treat; Especially for prostate etc., be positioned at the tissue of specific position, conventional ultrasonic imaging technique (B ultrasonic) can not form image clearly, therefore the above-mentioned locating and monitoring system with cavity 5 is more applicable.
When patient 39 lies on the back on therapeutic bed 1, ultrasonic medium accommodating unit 4 holds patient 39 hypogastric region and shank upper end (patient 39 health " passes " ultrasonic medium accommodating unit 4 in other words), and these positions are immersed in ultrasound wave transmitting medium.As shown in Figure 2, can have the protuberance 3 being positioned between 39 liang of lower limbs of patient on ultrasonic medium accommodating unit 4, this protuberance 3 is mainly used in motion to access ultrasonic medium accommodating unit 4, certainly, if this protuberance 3 is not feasible yet.
Preferably, on ultrasonic medium accommodating unit 4, there is the opening passing through for patient's 39 healths, opening connects one end of sealing shroud, the other end of sealing shroud has for supplying patient's 39 healths by also forming the hermetically-sealed construction that water-stops contact with patient's 39 body parts that pass through, thereby ultrasound wave transmitting medium can be sealed in ultrasonic medium accommodating unit 4.Preferably, sealing shroud can be fexible film material, and its hermetically-sealed construction can be the opening with tightening device, thereby it can produce close contact with the human body through opening.Because the material of sealing shroud, structure etc. can adopt known technology, therefore be not described in greater detail at this.By sealing shroud is set, the position to be treated that can make 4 of ultrasonic medium accommodating unit use hold patient 39, and other positions of patient's 39 healths can be stretched out outside ultrasonic medium accommodating unit 4 by sealing shroud, thereby reduce the volume of ultrasonic medium accommodating unit 4, reduce costs, make it adapt to the small space in cavity 51.Concrete, as shown in Figure 1, Figure 2, shown in Fig. 4 etc., in the present embodiment, on ultrasonic medium accommodating unit 4, there are two openings that pass through for patient's 39 shanks and an opening passing through for patient's 39 abdominal paries, each opening connects respectively 7 and abdominal part sealing shrouds 6 of two leg seal covers, leg seal cover 7 and the hermetically-sealed construction having respectively on abdominal part sealing shroud 6 for contacting with abdominal part formation water-stop with patient's 39 shanks.Certainly, different according to concrete purposes, the quantity of sealing shroud, position, shape etc. also can be different, for example, if when focused ultrasound therapy device is used for the treatment of the disease on top, abdominal cavity (as gastropathy), ultrasonic medium accommodating unit 4 should connect respectively a chest sealing shroud and an abdominal part sealing shroud.
Preferably, ultrasonic transducer 10 is that circular arc is planar; That is to say, ultrasonic transducer 10 is lamellar, and its surface is cambered surface, and this cambered surface is a part for sphere.The focus 33 of the ultrasonic transducer 10 of this form is just in time positioned at the centre of sphere place of its corresponding sphere, therefore its focus 33 location comparisons are easily definite, and focusing effect is good; Meanwhile, planar ultrasonic transducer 10 sizes of circular arc can be larger, so its power can be higher, can improve the ultrasonic energy at focus 33 places, to reach better therapeutic effect.
Concrete, it is planar that ultrasonic transducer 10 can be illustrated in figure 9 spherical crown.Wherein, " spherical crown " refers to the part of similar " crown " that obtain after a ball is cut by plane, and " spherical crown surface " refers to the surface of the arch section of this spherical crown.Ultrasonic transducer 10 simple shape that this spherical crown is planar, focus is easily determined.Or ultrasonic transducer 10 can as shown in Figure 6 to 8, be also each lamellar not waiting to size.
Because the planar ultrasonic transducer 10 of above-described various circular arcs can adopt existing product, therefore no longer their concrete form is described in detail at this.Certainly, it is planar that ultrasonic transducer 10 also can be other circular arc, or ultrasonic transducer 10 also can be other planar shapes of non-circular arc.
Preferably, as shown in Figure 3, in the present embodiment, ultrasonic transducer 10 has two, and their focus overlaps; By a plurality of ultrasonic transducers 10 being set, can improving the hyperacoustic energy intensity that acts on lesions position, improve therapeutic effect.Preferred, the equal diameters of the sphere of two ultrasonic transducer 10 correspondences, two ultrasonic transducers 10 have the parameters such as identical curvature, focal length in other words.Further preferred, as shown in Fig. 3, Fig. 6, Fig. 7, Fig. 8, Fig. 9, two ultrasonic transducers are symmetrical arranged with respect to their focus 33 (common focus 33); Ultrasonic transducer 10 advantages of this form are, the ultrasound wave passage 44 of two ultrasonic transducers 10 overlaps, thereby can reduce the impact of ultrasound wave on other positions of human body except lesions position as far as possible.
Concrete, one of them ultrasonic transducer 10 is located at patient 39 health front sides, in patient's 39 height directions in patient's 39 abdominal regions, and towards patient 39 prostatic; 10 of another ultrasonic transducers are located at patient's 39 health rear sides, in patient's 39 height directions in patient 39 buttocks positions, and towards patient 39 prostatic.Why ultrasonic transducer 10 is arranged by above-mentioned position, and be not set directly at the prostatic above and below of patient 39, be because the line of 10 of ultrasonic transducers arranging on the one hand like this with respect to vertical direction (short transverse of cavity 51 in other words) at an angle, therefore the distance of the two can be greater than the height of cavity 51, thereby can the in the situation that of cavity 51 interior limited space, use larger sized ultrasonic transducer 10 (corresponding its power is also larger, and therapeutic effect is better) as far as possible; On the other hand, if directly ultrasonic transducer 10 is located at patient 39 prostatic above or below, ultrasound wave is most of can be blocked by pubis and rumpbone, affect therapeutic effect, and its hetero-organizations such as pubis and rumpbone can be avoided in the position of the present embodiment ultrasonic transducer 10 as far as possible.
Preferred, when ultrasonic transducer 10 is positioned at above-mentioned position, as shown in Fig. 6, Fig. 7, Fig. 8, the diameter of the sphere of ultrasonic transducer 10 correspondences is between 350 millimeters to 650 millimeters; And in being parallel to the plane of patient's 39 height directions (or claim ultrasonic transducer 10 length direction) and the focus 33 by ultrasonic transducer 10, the central angle of ultrasonic transducer 10 correspondences (β angle) is between 20 degree to 120 degree (seeing Fig. 7), and in being parallel to the plane of patient's 39 health widths (or claim ultrasonic transducer 10 width) and the focus 33 by ultrasonic transducer 10, the central angle of ultrasonic transducer 10 correspondences (α angle) is between 15 degree to 60 degree (seeing Fig. 8).That is to say, ultrasonic transducer 10 preferably irregular circular arc is planar, and it is similar to the shape being intercepted on sphere by a rectangular area, and the size in all directions is different.Ultrasonic transducer 10 advantages of this form are: when it arranges by above-mentioned position, its ultrasound wave sending can be avoided patient 39 rumpbone and peripheral nerve tissue thereof completely, and can partly or entirely avoid patient 39 pubic symphysis, thereby reduce these tissues, to hyperacoustic, stop, and reduce the impact of ultrasound wave on human body as far as possible when guaranteeing therapeutic effect.Visible, the ultrasonic transducer 10 of above-mentioned form can be obtained best effect when treatment prostatosis.
Obviously, although be to lie on the back on therapeutic bed 1 as an example with patient 39 in the present embodiment, if be also feasible (therapeutic bed also can be used for the sleeping position of lying prone of immobilized patients 39 in other words) but patient 39 is lain prone crouch to treat on therapeutic bed 1, but now the position of two ultrasonic transducers 10 just should exchange.
Wherein, as shown in Figure 3, ultrasonic transducer 10 is connected on transducer mount 11, thereby is positioned in respectively precalculated position separately; Transducer mount 11 connects motion, thereby motion can drive ultrasonic transducer 10 motions by transducer mount 11.The advantage of this structure is: first, because motion drives ultrasonic transducer 10 by transducer mount 11, therefore the distance that motion and ultrasonic transducer are 10 can be far away, motion can be located at outside cavity 51 and (be located at least partly cavity 51 outer), its volume, position etc. are not subject to the restriction of cavity 51, can when being positioned at the cavity 51 of limited space, patient 39 effectively drive ultrasonic transducer 10 motions, thereby the locating and monitoring system 5 with cavity 51 is applicable in external treatment technology, to guarantee the clear of imaging, improve therapeutic effect; In addition, on transducer mount 11, can there are a plurality of different connecting positions (for example position of the top and bottom of transducer mount 11 connection ultrasonic transducer 10 in Fig. 3), thereby in the time will treating various disease, as long as the different connecting positions at transducer mount 11 arrange different ultrasonic transducers 10, thereby can change easily quantity, position, size, model of ultrasonic transducer 10 etc., make focused ultrasound therapy device can be used for the treatment of multiple different disease.
Preferably, two ultrasonic transducers 10 are connected on same transducer mount 11.The advantage of this structure is: on the one hand, as long as the connecting position on pre-set transducer mount 11, when two ultrasonic transducers 10 are connected on transducer mount 11, can directly realize focus 33 overlaps, and can keep this correct relative position always, and need not adjust one by one again ultrasonic transducer 10; On the other hand, like this as long as a set of motion can drive a plurality of ultrasonic transducers 10 simultaneously, and can guarantee the synchronous of their motions always, thus the structure of simplification device.
Obviously, although the present embodiment with two ultrasonic transducers 10 as an example, ultrasonic transducer 10 also has three or more.Wherein, when ultrasonic transducer 10 has when a plurality of, their focus preferably overlaps, and the diameter of their corresponding spheres preferably all equates; Preferred, all ultrasonic transducers 10 are connected on a transducer mount 11.
Motion drives ultrasonic transducer 10 in the 4 interior motions of ultrasonic medium accommodating unit and changes its focus 33 positions for (by transducer mount 11), thereby the image providing according to locating and monitoring system 5 accurately moves to lesions position by ultrasound focus 33, to reach best therapeutic effect.
Motion can comprise and is respectively used to drive ultrasonic transducer 10 at X-direction motion, Y-direction motion, the Z-direction motion of directions X, Y-direction, the motion of Z direction.As shown in Figure 1, Z direction is patient's 39 height directions, and directions X is the direction of patient's 39 health width, and Y-direction is simultaneously perpendicular to directions X and Z direction.The advantage of this motion is: ultrasonic transducer 10 is all removable in all directions, and degree of freedom is larger; Ultrasonic transducer 10 motion in different directions is simultaneously realized by different institutions respectively, therefore motion is relatively simple for structure.
Concrete, Y-direction motion is the first rotational motion mechanism, is arranged in ultrasonic medium accommodating unit 4, by rotating shaft 16, is connected with X-direction motion.As shown in Fig. 3, Fig. 5, the first rotational motion mechanism comprises the first electric rotating machine 15 in the annular seal space 28 that is located at rotating shaft 16, its output shaft stretches out annular seal space 28 by O RunddichtringO 27, and drive the first driving-belt 12 by the first belt wheel 14, the two ends of transducer mount 11 are also provided with projection 29, and it stretches in the arc guide groove 30 of rotating shaft 16 inner sides, end; The two ends of the first driving-belt 12 are affixed transducer mount 11 respectively, and is provided with and is respectively equipped with on two connecting positions that 13, two ultrasonic transducers 10 of contact roller are connected to the two ends that connect transducer mount 11 with the joint of transducer mount 11.During the first electric rotating machine 15 rotation, can drive transducer mount 11 to rotate around X-axis, thereby make ultrasonic transducer 10 focuses 33 move in the Y direction (certainly, focus 33 also can produce very little motion simultaneously in Z direction).
X-direction motion is the second rotational motion mechanism, and it is located at guide rail 2O above and is connected with the second driving-belt 22.The second rotational motion mechanism comprises the carrying position 21 of the second electric rotating machine 20 and carrying rotating shaft 16, the second electric rotating machine 20 drives rotating shaft 16 to rotate around Z axis by gear 18,19, and then drive Y-direction motion (also driving ultrasonic transducer 10 simultaneously) to rotate around Z axis, make thus ultrasonic transducer 10 focuses 33 move (certainly, focus 33 also can produce very little motion in the Y direction) on directions X.Wherein, rotating shaft 16 is stretched into ultrasonic medium accommodating unit 4 by the opening on ultrasonic medium accommodating unit 4, rotating shaft 16 overcoat corrugated flexible hoses 8, and corrugated flexible hose 8 one end connect above-mentioned opening, the other end is connected with rotating shaft carrying position 21, in rotating shaft 16 and 21, position of carrying, also can be provided with O RunddichtringO 17.Corrugated flexible hose 8 can be made by materials such as rubber, and it can, by 4 sealings of ultrasonic medium accommodating unit, allow again the motion of rotating shaft 16.
Z-direction motion is straight-line motion mechanism, it comprises connection guide rail 26, the 3rd electric rotating machine 25, the second belt wheel 24, the 3rd belt wheel 23, the second driving-belt 22, its middle guide 26 and the second driving-belt 22 are all along directions X setting, the second driving-belt 22 is enclosed within on belt wheel 23,24, the 3rd electric rotating machine 25 can drive the second belt wheel 24 to rotate and drive 22 of the second driving-belt 22, the second driving-belts to drive X-direction motion (also driving Y-direction motion, ultrasonic transducer 10) to move up in Z side.
The advantage of above-mentioned motion is: X-direction motion, Y-direction motion are rotational motion mechanism, therefore volume does not change when they drive, can not make the liquid level in ultrasonic medium accommodating unit 4 change yet, and slight change (being caused by the flexible of corrugated flexible hose 8) only occurs Z-direction motion liquid level in ultrasonic medium accommodating unit 4 when driving, and stable liquid level is conducive to improve the image quality of magnetic resonance imaging system and electronic computer x-ray tomography imaging system; In addition, the length direction of above motion is consistent with the length direction of cavity 51, and the size making progress in the footpath of cavity 51 is less, therefore can well drive ultrasonic transducer 10 by transducer mount 11 in the cavity 51 of limited space.
Certainly, above motion is a kind of in the various ways that can take of motion, and motion also can be many other different forms.
Certainly, in the focused ultrasound therapy device of the present embodiment, also should comprise other necessary device, as the power supply unit for to device bulk supply, for controlling the control unit of ultrasonic transducer 10 and motion, for showing the display unit of the image that locating and monitoring system 5 gathers, be used to ultrasonic medium accommodating unit 4 to be filled with or to emit the unit that charges and discharge of ultrasound wave transmitting medium, for making therapeutic bed 1 and ultrasonic medium accommodating unit 4 enter or shift out the therapeutic bed mobile unit etc. of the cavity 51 of locating and monitoring system 5.
The present embodiment provides a kind of prostatosis focused ultrasound therapy device, and it has the similar structure of prostatosis focused ultrasound therapy device with embodiment 2.The difference of the prostatosis focused ultrasound therapy device of the present embodiment and the prostatosis focused ultrasound therapy device of embodiment 2 is: as shown in figure 10, in the present embodiment, ultrasonic medium accommodating unit 4 has two, lay respectively at the above and below of patient's 39 healths, two ultrasonic transducers 10 lay respectively at (but its position with respect to patient's 39 healths can be in the same manner as in Example 2) in two ultrasonic medium accommodating unit 4.
Wherein, ultrasonic medium accommodating unit 4 lower ending openings of patient 39 health tops, this opening is sealed by sound passing membrane 45, under the effect of gravity etc., sound passing membrane 45 deformables are sagging and contact with patient 39 abdominal part, thereby the ultrasound wave that ultrasonic transducer 10 sends can and import patient's 39 abdominal paries into through ultrasound wave transmitting medium.
The ultrasonic medium accommodating unit 4 that is located at patient 39 health belows is arranged in the holding part of therapeutic bed 1, and its upper end open, therefore patient 39 buttocks can be immersed in the ultrasound wave transmitting medium in this ultrasonic medium accommodating unit 4, thereby the ultrasound wave that ultrasonic transducer 10 sends can import patient's 39 buttocks into via ultrasound wave transmitting medium.
Certainly, the above-mentioned ultrasonic medium accommodating unit 4 with sound passing membrane 45 is not limited to be positioned at patient 39 healths tops.Either party (for example two sides of horizontal direction) of patient's 39 healths all can be provided with ultrasonic medium accommodating unit 4, and this ultrasonic medium accommodating unit 4 is towards patient's direction opening, and opening can be sealed with the sound passing membrane 45 of patient's 39 Body contact.If when for example ultrasonic medium accommodating unit 4 is around patient's 39 health, sound passing membrane 45 also can be the circulus around patient body.
The advantage of the prostatosis focused ultrasound therapy device of the present embodiment is: patient 39 health is immersed in area in ultrasound wave transmitting medium and has reduced, therefore patient 39 treatment is experienced better; Simultaneously, wherein needn't use sealing shroud etc. that ultrasound wave transmitting medium is sealed in ultrasonic medium accommodating unit 4, and the sealing between motion and ultrasonic medium accommodating unit 4 is also simpler, thereby can simplify the structure of focused ultrasound therapy device, reduce costs and risk that ultrasound wave transmitting medium leaks.
The present embodiment provides a kind of prostatosis focused ultrasound therapy device, has the similar structure of prostatosis focused ultrasound therapy device with embodiment 3, and difference is:
As shown in figure 11, in the prostatosis focused ultrasound therapy device of the present embodiment, only have a ultrasonic transducer 10 and a ultrasonic medium accommodating unit 4, this ultrasonic transducer 10 is positioned at patient's 39 health upsides (being front side), ultrasonic medium accommodating unit 4 is located at patient 39 health tops, lower ending opening, opening is sealed by sound passing membrane 45; On therapeutic bed 1, there is no holding part and ultrasonic medium accommodating unit 4.
Now, owing to there is no holding part and ultrasonic medium accommodating unit 4 on therapeutic bed 1, so it can directly adopt the conventional bed body in locating and monitoring system 5, thereby reduces the cost of device.
The present embodiment provides a kind of prostatosis focused ultrasound therapy device, has the similar structure of prostatosis focused ultrasound therapy device with embodiment 3, and difference is:
As shown in figure 12, in the prostatosis focused ultrasound therapy device of the present embodiment, only have a ultrasonic transducer 10 and a ultrasonic medium accommodating unit 4, this ultrasonic transducer 10 is positioned at patient's 39 health downsides (being rear side), in the holding part that ultrasonic medium accommodating unit 4 is located on therapeutic bed 1, and upper end open; Patient 39 health tops do not have ultrasonic medium accommodating unit 4, sound passing membrane 45 etc.
The advantage of the prostatosis focused ultrasound therapy device that only has a ultrasonic transducer 10 of example 4 and embodiment 5 is in real time: on the one hand, its ultrasonic transducer 10 quantity are few, the volume occupying is also less, therefore be more conducive to make prostatosis focused ultrasound therapy device and the locating and monitoring system 5 with cavity 51 to adapt; Meanwhile, it is relatively simple for structure, and cost is low.
As shown in Figure 11 and Figure 12, in real time in the prostatosis focused ultrasound therapy device of example 4 and embodiment 5, owing to only having a ultrasonic transducer 10, therefore also only have respectively a connecting position on its transducer mount 11; But obviously, also can use the transducer mount 11 (example transducer mount 11 as shown in Figure 3) of a plurality of connecting positions in these two embodiment, just on transducer mount 11, only use and connect a ultrasonic transducer 10, other connecting position can vacancy.
Of course it is to be understood that those skilled in the art also can carry out many variations to the focused ultrasound therapy device of the various embodiments described above, for example: ultrasonic transducer also can be three or more; The position of ultrasonic transducer, shape, size etc. can be different; The shape of transducer mount, size, connecting position quantity, connecting position position can be different; Ultrasonic medium accommodating unit also can be other size and dimension, thereby for holding other positions such as pelvic cavity, abdominal cavity, thoracic cavity of patient, for (corresponding ultrasonic transducers locations also will be adjusted) such as treatment hepatopathy, nephropathy, pancreatic diseases, pneumonopathy; Patient also can lie prone and crouch or lie on one's side on therapeutic bed (corresponding ultrasonic transducers locations also will be adjusted); The concrete form of motion can be not equal.
Be understandable that, above embodiment is only used to principle of the present invention is described and the illustrative embodiments that adopts, yet the present invention is not limited thereto.For those skilled in the art, without departing from the spirit and substance in the present invention, can make various modification and improvement, these modification and improvement are also considered as protection scope of the present invention.
Claims (18)
1. a focused ultrasound therapy device, is characterized in that, comprising:
For holding the ultrasonic medium accommodating unit of ultrasound wave transmitting medium;
At least one is positioned at the ultrasonic transducer of described ultrasonic medium accommodating unit, for sending concentration ultrasonic, during treatment described in the ultrasound wave conduction that ultrasonic transducer can be sent of ultrasound wave transmitting medium to patient body;
Be used for the motion that drives described ultrasonic transducer to move and change its focal position in ultrasonic medium accommodating unit;
With the transducer mount that described motion is connected, described ultrasonic transducer is connected on transducer mount;
For at least forming the locating and monitoring system of the image at patient position to be treated, it has can hold the cavity at described ultrasonic medium accommodating unit and patient position to be treated when treatment;
For the therapeutic bed of immobilized patients position, during treatment described in therapeutic bed be positioned at least partly the cavity of described monitoring system.
2. focused ultrasound therapy device according to claim 1, is characterized in that, described focused ultrasound therapy device is prostatosis focused ultrasound therapy device, and wherein said therapeutic bed is for being fixed patient's the sleeping position of lying on the back or lie prone.
3. focused ultrasound therapy device according to claim 2, is characterized in that,
Described ultrasonic transducer is that circular arc is planar, the part that described arc surface is sphere.
4. focused ultrasound therapy device according to claim 3, is characterized in that, described ultrasonic transducer is one, and
This ultrasonic transducer is located at patient body front side, in patient's height direction in patient's abdominal region, and towards patient's prostatic;
Or
This ultrasonic transducer is located at patient body rear side, in patient's height direction in patient's buttocks position, and towards patient's prostatic.
5. focused ultrasound therapy device according to claim 4, is characterized in that,
The diameter of the sphere that described ultrasonic transducer is corresponding is between 350 millimeters to 650 millimeters;
Be parallel to patient's height direction and passing through in the plane of ultrasonic transducer focus, central angle corresponding to described ultrasonic transducer is between 20 degree to 120 degree, be parallel to patient body width and by the plane of ultrasonic transducer focus, central angle corresponding to described ultrasonic transducer is between 15 degree to 60 degree.
6. focused ultrasound therapy device according to claim 4, is characterized in that,
When described ultrasonic transducer is located at patient body top, patient body top is also located in described ultrasonic medium accommodating unit, and the lower ending opening of described ultrasonic medium accommodating unit, and described opening is sealed by the sound passing membrane that can contact with patient body;
Or
When described ultrasonic transducer is located at patient body below, described therapeutic bed is provided with the holding part of depression, and described ultrasonic medium accommodating unit is located in described holding part, and upper end open.
7. focused ultrasound therapy device according to claim 3, is characterized in that, described ultrasonic transducer is two, and is connected on a transducer mount, and the focus of two ultrasonic transducers overlaps, and the equal diameters of corresponding sphere, wherein:
A ultrasonic transducer is located at patient body front side, in patient's height direction in patient's abdominal region, and towards patient's prostatic;
Another ultrasonic transducer is located at patient body rear side, in patient's height direction in patient's buttocks position, and towards patient's prostatic.
8. focused ultrasound therapy device according to claim 7, is characterized in that, two described ultrasonic transducers are symmetrical arranged with respect to their focus.
9. focused ultrasound therapy device according to claim 8, is characterized in that,
The diameter of the sphere that described ultrasonic transducer is corresponding is between 350 millimeters to 650 millimeters;
Be parallel to patient's height direction and passing through in the plane of ultrasonic transducer focus, central angle corresponding to described ultrasonic transducer is between 20 degree to 120 degree, be parallel to patient body width and by the plane of ultrasonic transducer focus, central angle corresponding to described ultrasonic transducer is between 15 degree to 60 degree.
10. focused ultrasound therapy device according to claim 7, is characterized in that,
Described therapeutic bed is provided with the holding part of depression, and the bottom of described ultrasonic medium accommodating unit is positioned at described holding part;
On described ultrasonic medium accommodating unit, there are two openings that pass through for patient's shank, each opening is all connected with one end of a leg seal cover, and the other end of described leg seal cover has can be for patient's shank by also forming the hermetically-sealed construction that water-stop contact with patient's shank;
On described ultrasonic medium accommodating unit, there is an opening passing through for patient's abdominal part, this opening is connected with one end of abdominal part sealing shroud, and the other end of described abdominal part sealing shroud has can be for patient's abdominal part by also forming the hermetically-sealed construction that water-stop contact with patient's abdominal part.
11. focused ultrasound therapy devices according to claim 7, is characterized in that, described ultrasonic medium accommodating unit has two, lays respectively at the above and below of patient body, and two ultrasonic transducers lay respectively in two ultrasonic medium accommodating unit, wherein:
Be positioned at the ultrasonic medium accommodating unit lower ending opening of patient body top, and described opening is sealed by the sound passing membrane that can contact with patient body;
Described therapeutic bed is provided with the holding part of depression, described in be arranged in patient body below ultrasonic medium accommodating unit be located at described holding part, and upper end open.
12. focused ultrasound therapy devices according to claim 1, is characterized in that, described ultrasonic transducer is that circular arc is planar, the part that described arc surface is sphere.
13. focused ultrasound therapy devices according to claim 12, is characterized in that, described ultrasonic transducer has one;
Or
Described ultrasonic transducer has at least two, and the focus of each ultrasonic transducer overlaps, and the equal diameters of sphere corresponding to each ultrasonic transducer.
14. focused ultrasound therapy devices according to claim 13, is characterized in that,
Described ultrasonic transducer has at least two, and all ultrasonic transducers are connected on a transducer mount.
15. focused ultrasound therapy devices according to claim 1, is characterized in that,
Described ultrasonic medium accommodating unit is provided with the opening for passing through for patient body, and opening is connected with one end of sealing shroud, and the other end of described sealing shroud has can be for patient body by also forming the hermetically-sealed construction that water-stop contact with the patient body passing through.
16. focused ultrasound therapy devices according to claim 1, is characterized in that,
Described ultrasonic medium accommodating unit is in the direction upper shed towards patient body, and described opening is sealed by the sound passing membrane that can contact with patient body.
17. focused ultrasound therapy devices according to claim 1, is characterized in that, described therapeutic bed is provided with the holding part of depression, and described ultrasonic medium accommodating unit is arranged in described holding part, and described ultrasonic medium accommodating unit upper end open.
18. according to the focused ultrasound therapy device described in any one in claim 1 to 17, it is characterized in that,
Described locating and monitoring system is magnetic resonance imaging system or electronic computer x-ray tomography imaging system.
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