TWI621460B - High-intensity focused ultrasound treatment apparatus - Google Patents

Abstract

A high-energy focusing ultrasonic therapy device, comprising an ultrasonic imaging device, a display device, a first positioning device and a high-energy focusing ultrasonic device, wherein: the ultrasonic imaging device has an ultrasonic scanner for an operator Ultrasonic scanning is performed on a first position on a patient's body surface to capture an ultrasonic image; the display device is configured to receive and display an ultrasonic image captured by the ultrasonic imaging device; the first positioning The device is configured to receive a target position in the ultrasonic image displayed by the display device, and generate a first positioning signal; the high-energy focusing ultrasonic device is configured to receive the first positioning device. The first positioning signal is generated and moved to a second position on the body surface of the patient according to the first positioning signal, thereby guiding a focused energy to a position corresponding to the target position in the patient.

Description

High-energy focused ultrasonic therapy equipment

The present invention relates to a high-energy focused ultrasonic therapy device, in particular to a positioning using only an ultrasonic imaging device, and the positioning ultrasonic imaging device and the therapeutic high-energy focusing ultrasonic device are arranged in a non-coaxial manner. A high-energy focused ultrasound therapy device that allows the operator to indicate the target location with a virtual axis and a virtual reference point.

High-energy focused ultrasound therapy is a non-invasive treatment that uses a large portion of the energy of a high-energy focused ultrasound to be transmitted to a target location (focus) in a patient for treatment. High-energy focused ultrasound therapy is widely used in clinical applications, including the treatment of benign or malignant tumors, the opening of blood-brain barriers, hemostasis, thrombolysis, drug and gene delivery, and dermatology, among which Advantage.

For the treatment of tumors, common non-invasive therapies include chemotherapy and radiation therapy. Among them, chemotherapy is aimed at the rapid division of tumor cells to destroy tumor cells, so it will inevitably affect the normal growth of fast cells, and some chemotherapy drugs may also cause heart, lung, kidney, liver, bladder and Damage to the cells of the nervous system; when treated with radiation, there is a certain degree of damage to the surrounding tissues of the tumor, and repeated use will also expose the patient to the potential risks associated with the accumulation of doses.

In contrast, high-energy focused ultrasound therapy accurately directs most of the energy of the high-energy focused ultrasound to the target location within the patient, along the guiding path (from the patient's body) The energy that the tissue passing through the path between the table and the target position in the body will be extremely low and will not be destroyed. Furthermore, since the use of high-energy focused ultrasound does not have the problem of dose accumulation as with radiation therapy, and does not cause various side effects such as the use of chemotherapeutic drugs, it is quite safe to use.

How to position the high-energy focused ultrasound to be guided to the target position in the patient is the key to the implementation of high-energy focused ultrasound therapy. In terms of guiding positioning, coaxial ultrasonic positioning and nuclear magnetic resonance positioning have been used. In the aspect of coaxial ultrasonic positioning, the general practice is to perform preliminary positioning with a diagnostic ultrasonic device, and then perform treatment at the aforementioned positioning position with a high-energy focused ultrasonic device. In terms of NMR positioning, the NMR scanning device is used for stereotactic positioning in the patient's body, and then treated with a high-energy focused ultrasound device.

However, when coaxial ultrasonic positioning is used, it is necessary to alternately move the diagnostic ultrasonic device and the high-energy focusing ultrasonic device, which is troublesome in use. When using nuclear magnetic resonance positioning, the NMR scanning device used is not only expensive in itself, but also requires a large space and is not easy to operate, and it is often necessary to integrate the high-energy focusing ultrasonic device with the nuclear magnetic resonance scanning device in application. Increase the cost of its use.

The technical problems to be solved by the present invention include: the inconvenience of the conventional diagnostic ultrasonic device and the high-energy focusing ultrasonic device, and the difficulty in integration, and how to improve the accuracy of ultrasonic diagnosis. Therefore, in order to make up for the deficiencies of the prior art, the inventors have accumulated many years of experience and continuous research and development improvements, and the present invention has been produced.

One of the main objects of the present invention is to provide a combination of a positioning ultrasonic ultrasonic imaging device and a high-energy focusing ultrasonic device for positioning using only an ultrasonic imaging device, and providing an operator with a virtual axis and a virtual Reference point indicates the target position High-energy focused ultrasound therapy equipment.

Another object of the present invention is to provide a simultaneous ultrasonic scanning of a plurality of positions on a patient's body surface by a plurality of ultrasonic scanners to construct a three-dimensional ultrasonic image and provide an operator with a virtual axis and a virtual reference point. The constructed three-dimensional ultrasonic image indicates a high-energy focused ultrasonic therapy device at the target position.

In order to achieve the foregoing objects and produce the expected technical effects, the present invention provides a high-energy focused ultrasonic therapeutic apparatus, including an ultrasonic imaging apparatus, a display apparatus, a first positioning apparatus, and a high-energy focusing ultrasonic apparatus, wherein: The sound wave imaging device has an ultrasonic scanner for an operator to perform ultrasonic scanning on a first position on a patient's body surface to capture an ultrasonic image; the display device is configured to receive and display the foregoing The ultrasonic image captured by the ultrasonic imaging device; the first positioning device is configured to allow the operator to mark a target position in the ultrasonic image displayed by the display device, and generate a first positioning signal according to the foregoing; The focusing ultrasonic device is configured to receive the first positioning signal generated by the first positioning device, and is moved to a second position on the body surface of the patient according to the first positioning signal, thereby further focusing energy Guided to the patient's body corresponding to the aforementioned target location.

In implementation, the high-energy focused ultrasonic therapy device further includes an image processing device, and the ultrasonic imaging device further includes another ultrasonic scanner; wherein the other ultrasonic scanner is provided to the operator for a patient body. The third position of the table is ultrasonically scanned to capture the ultrasonic image; the image processing device is configured to process the ultrasonic image captured from the first position and the third position, and construct a correspondence a three-dimensional ultrasonic image of the internal anatomy of the patient; the display device is configured to receive and display a three-dimensional ultrasonic image constructed by the ultrasonic imaging device; and the first positioning device is provided by the operator in the foregoing three-dimensional A target position is indicated in the ultrasonic image, and a first positioning signal is generated accordingly.

In implementation, the aforementioned high-energy focused ultrasonic therapy device further includes a second positioning The device is configured to detect an orientation of the ultrasonic scanner of the ultrasonic imaging device, and generate a second positioning signal, wherein the high-energy focusing ultrasonic device receives the first positioning device The first positioning signal and the second positioning signal generated by the second positioning device are moved to the second position on the body surface of the patient according to the first positioning signal and the second positioning signal, thereby guiding a focusing energy To the patient's body corresponding to the aforementioned target position.

In implementation, the display device displays a virtual axis and a virtual reference point movable along the virtual axis in the displayed ultrasonic image, for the operator to move the virtual reference point to a target position to generate the foregoing The first positioning signal. In one embodiment, the virtual axis is a longitudinal center axis; in another embodiment, the virtual axis is a lateral center axis.

In implementation, the display device displays, in the displayed ultrasonic image, two virtual axes intersecting each other and a virtual reference point movable along the two virtual axes, for the operator to move the virtual reference point to a target. Position to generate the aforementioned first positioning signal.

In implementation, the high-energy focused ultrasonic therapy device further includes an automatic displacement device that controls the movement of the ultrasonic scanner of the ultrasonic imaging device and the high-energy focused ultrasonic device by a robot arm.

For a better understanding of the features and functions of the present invention, the embodiments are described in detail below with reference to the drawings.

1, 1'‧‧‧High-energy focused ultrasound therapy equipment

10‧‧‧Ultrasonic imaging device

102‧‧‧Ultrasonic scanner

104‧‧‧ Wide-angle probe

106‧‧‧Two-dimensional ultrasound image

1062‧‧‧Effective area

1064‧‧‧ Anatomical structure

11‧‧‧ display device

112‧‧‧Virtual axis

114‧‧‧virtual reference point

116‧‧‧ Target location

12‧‧‧First positioning device

122‧‧‧First positioning signal

13‧‧‧High-energy focused ultrasonic device

132‧‧‧ Probe

14‧‧‧Automatic displacement device

142‧‧‧ Robotic arm

144‧‧‧ first position

146‧‧‧second position

148‧‧‧ third position

15‧‧‧Second positioning device

152‧‧‧Second positioning signal

16‧‧‧Image processing device

162‧‧‧Three-dimensional ultrasound image

17, 17’‧‧‧ wearing parts

172‧‧‧Outer layer

174‧‧‧ inner filling layer

18, 19‧‧‧ hollow transmission cabin

180, 190‧‧ ‧ water inlet

181, 191‧‧ ‧ water outlet

182, 192‧‧‧ space

183, 193‧‧‧Ultrasonic conducting media

194‧‧‧ inner cabin

184‧‧‧ cover

185, 195‧‧ Track

186, 196‧‧‧ body

2‧‧‧ platform

Fig. 1A is a schematic view showing the structure of a first embodiment of the high energy focused ultrasonic therapeutic apparatus of the present invention.

Figure 1B shows the ultrasonic scanner and the high-energy focused ultrasonic device in Figure 1A. A schematic diagram of the use.

2A-2B are diagrams showing the use of a virtual axis and a virtual reference point in the first embodiment of the high energy focused ultrasonic therapy apparatus of the present invention.

3A to 3C are views showing the structure of the ultrasonic scanner in the first embodiment of the high-energy focused ultrasonic treatment apparatus of the present invention.

Fig. 4A is a schematic view showing the structure of a second embodiment of the high energy focused ultrasonic therapeutic apparatus of the present invention.

Fig. 4B is a view showing the use of the ultrasonic scanner and the high energy focused ultrasonic device in Fig. 4A.

5A-5B are diagrams showing the processing of the captured two-dimensional ultrasonic image by the image processing apparatus in the second embodiment of the high-energy focused ultrasonic therapeutic apparatus of the present invention.

6A to 6B are views showing the use of the virtual axis and the virtual reference point in the second embodiment of the high energy focused ultrasonic therapy apparatus of the present invention.

Figure 7 is a schematic illustration of another aspect of the use of a virtual axis and a virtual reference point in a high energy focused ultrasound therapy device of the present invention.

Fig. 8A is a view showing the structure of the ultrasonic transmission medium used in the first embodiment of the high energy focusing ultrasonic treatment apparatus of the present invention.

Fig. 8B is a schematic cross-sectional view showing the structure of the ultrasonic transmission medium in Fig. 8A taken along the line AA'.

Fig. 8C is a view showing the structure of the ultrasonic transmission medium used in the second embodiment of the high energy focused ultrasonic treatment apparatus of the present invention.

Fig. 8D is a schematic cross-sectional view showing the structure of the ultrasonic transmission medium in Fig. 8C taken along the line BB'.

Fig. 9A is a view showing another embodiment of the structure of the ultrasonic transmission medium used in the high energy focused ultrasonic therapeutic apparatus of the present invention.

Fig. 9B is a schematic cross-sectional view showing the structure of the ultrasonic transmission medium in Fig. 9A taken along line CC'.

Fig. 10A is a schematic view showing still another embodiment of the structure of the ultrasonic transmission medium used in the high energy focused ultrasonic therapeutic apparatus of the present invention.

Fig. 10B is a schematic cross-sectional view showing the structure of the ultrasonic transmission medium in Fig. 10A taken along the line DD'.

Fig. 10C is a view showing the state of use of the structure of the ultrasonic transmission medium in Fig. 10A.

The present invention relates to a high energy focused ultrasound therapeutic apparatus comprising an ultrasonic imaging device, a display device, a first positioning device and a high energy focusing ultrasonic device. The ultrasonic imaging device has an ultrasonic scanner for an operator to perform ultrasonic scanning on a first position on a patient's body surface to capture an ultrasonic image; the display device is configured to receive and Displaying the ultrasonic image captured by the ultrasonic imaging device; the first positioning device is configured to allow the operator to mark a target position in the ultrasonic image displayed by the display device, and generate a first positioning signal accordingly; The high-energy focusing ultrasonic device receives the first positioning signal generated by the first positioning device, and is moved to a second position on the body surface of the patient according to the first positioning signal, thereby further focusing energy Guided to the patient's body corresponding to the aforementioned target location.

Please refer to FIG. 1A, which is a schematic diagram showing the architecture of a first embodiment of a high energy focused ultrasound therapeutic apparatus of the present invention. As shown in FIG. 1A, the high-energy focusing ultrasonic therapy device 1 of the present invention mainly comprises an ultrasonic imaging device 10, a display device 11, a first positioning device 12, a high-energy focusing ultrasonic device 13, and an automatic Displacement device 14.

In the present embodiment, the ultrasonic imaging device 10 has an ultrasonic scanner 102 for performing ultrasonic scanning on a patient's body surface to capture the two-dimensional ultrasonic image 106. The display device 11 is configured to display the captured two-dimensional ultrasonic image 106, and the operator can mark the displayed two-dimensional ultrasonic image 106 by the first positioning device 12. The high-energy focusing ultrasonic device 13 has a probe 132, and the probe 132 is a large-area probe with better geometric focusing characteristics for transmitting high-energy ultrasonic waves.

When the two-dimensional ultrasonic image 106 is displayed on the display device 11, the operator can control the first positioning device 12, and mark a target position in the displayed two-dimensional ultrasonic image 106, and generate a first A positioning signal 122. Please refer to FIGS. 2A-2B for a schematic diagram showing the operator using the first positioning device 12 to mark. As shown in FIG. 2A, the display device 11 displays a longitudinal virtual axis 112 and a virtual reference point 114 movable along the virtual axis 112 in the displayed image (two-dimensional ultrasonic image). As shown in FIG. 2B, the operator can move the virtual reference point 114 to a target position 116 via the first positioning device 12, and after confirming the target position 116, the first positioning device 12 will generate a first The signal 122 is located and transmitted to the aforementioned automatic displacement device 14 to control the movement of the high energy focused ultrasonic device 13 through the automatic displacement device 14. In the implementation, the aforementioned virtual axis can also be designed as a movable person; in this example, the operator can also control the movement of the virtual axis by the aforementioned first positioning device.

In the implementation, as shown in FIG. 1B, the automatic displacement device 14 first moves the ultrasonic scanner 102 of the ultrasonic imaging device 10 to the first position 144 of the patient's body surface by the robot arm 142 for ultrasonic scanning. To capture the two-dimensional ultrasonic image 106. After the operator completes the indication of the target position via the first positioning device 12, the generated first positioning signal 122 will control the high-energy focusing ultrasonic device 13 to move to a second position 146, thereby guiding a focused energy to The patient's body corresponds to the aforementioned target position. As shown in FIG. 1B, in this embodiment, The ultrasonic imaging device 10 and the high-energy focusing ultrasonic device 13 are non-coaxial setters.

The aforementioned automatic displacement device 14 controls the movement of the ultrasonic scanner 102 by the robot arm 142. In addition to controlling the movement of the ultrasonic scanner 102, the robot arm 142 can also rotate the ultrasonic scanner along an axis in the up-and-down or left-right direction, thereby significantly increasing the scanning range. Before performing the ultrasonic scanning, the position of the body surface to be subjected to ultrasonic scanning and the configuration of the ultrasonic scanner to be used may be determined in advance according to the anatomical structure of the target to be detected.

The aforementioned ultrasonic scanner can also be modified in configuration to augment its application level. For example, referring to Figure 3A, the ultrasonic scanner can be designed to have a convex wide-angle probe (preferably having a scan angle of 60-120 degrees), thereby increasing the detection range of the ultrasonic scanner. In addition, the ultrasonic scanner can also be configured according to the anatomical structure of the scanning body surface. For example, please refer to Figures 3B and 3C, wherein the ultrasonic scanner is configured as a long strip, and its convex wide angle The probe system is disposed on its long side or short side side, thereby being applied to, for example, scanning between ribs.

In the implementation, in order to overcome the obstacle caused by the limitation of the surface anatomy when the ultrasonic scanner scans the human body surface, the high energy focused ultrasonic therapeutic apparatus of the present invention may further comprise an ultrasonic conductive medium structure. In the present embodiment, as shown in FIG. 8A, the ultrasonic conductive medium structure is configured as a wearing member 17 for being worn on a patient.

Please refer to Fig. 8B, which is a cross-sectional view showing the structure of the ultrasonic transmission medium in Fig. 8A taken along the line AA'. In the present embodiment, the wearing member 17 includes an outer skin 172 and an inner filling layer 174 covered by the outer skin 172. The outer surface layer 172 is made of a solid ultrasonic conducting medium, and the inner filling layer 174 is composed of a liquid or gel-like ultrasonic conducting medium. In addition, the solid ultrasonic transmission medium from which the outer skin layer 172 is formed has good compliance, whereby it can be closely attached to the patient's body to avoid any air gap. In the embodiment, the wearing part is exemplified by a vest, and may be implemented according to actual needs. It is configured in other types of clothing (such as pants, neck covers, sleeves, etc.).

Please refer to FIG. 4A, which is a schematic diagram showing the structure of a second embodiment of the high energy focusing ultrasonic therapeutic apparatus of the present invention. As shown in FIG. 4A, the high-energy focused ultrasonic therapeutic apparatus 1' of the present invention mainly comprises an ultrasonic imaging device 10, a display device 11, a first positioning device 12, a high-energy focusing ultrasonic device 13, and a The automatic displacement device 14, a second positioning device 15, and an image processing device 16.

In the present embodiment, the ultrasonic imaging device 10 has a plurality of ultrasonic scanners 102 for simultaneously performing ultrasonic scanning on a plurality of positions on a patient's body surface to capture a plurality of two-dimensional ultrasonic images 106. The image processing device 16 is configured to process a plurality of two-dimensional ultrasonic images 106 captured by the ultrasonic imaging device 10, thereby constructing a three-dimensional ultrasonic image 162 corresponding to the anatomical structure of the patient. The display device 11 is configured to display the constructed three-dimensional ultrasonic image 162, and the operator can mark the displayed three-dimensional ultrasonic image 162 by the first positioning device 12, and generate a first positioning signal 122 accordingly. The high-energy focusing ultrasonic device 13 has a probe 132 which is a large-area probe with better geometric focusing characteristics for transmitting high-energy ultrasonic waves. The second positioning device 15 is configured to detect the orientation of the plurality of ultrasonic scanners 102 and generate a second positioning signal 152.

In implementation, the aforementioned ultrasonic imaging device 10 may be a B mode ultrasonic imaging device, a Doppler mode ultrasonic imaging device, an elastic pattern mode ultrasonic imaging device, or a combination thereof, thereby taking a B mode, Doppler Two-dimensional ultrasonic image of mode and elastic pattern mode. The plurality of captured two-dimensional ultrasonic images can be processed by the image processing device 16 to generate a three-dimensional ultrasonic image in the following manner: as shown in FIG. 5A, the image processing device 16 first analyzes the plurality of captured two-dimensional images. The ultrasonic image 106 selects an effective region 1062 in each of the two-dimensional ultrasonic images 106; subsequently, as shown in FIG. 5B, the anatomical structure 1064 appears in each effective region 1062, and then is valid according to the plurality of the aforementioned plurality of Correlation of marked anatomical structures in the region, with supersonics The information such as the position and orientation of the wave scanner (i.e., the information obtained by the second positioning device 15) can be used to construct the three-dimensional ultrasonic image 162, for example, by volume imaging.

Subsequently, the constructed three-dimensional ultrasonic image 162 will be displayed in the aforementioned display device 11. At this time, the operator can use the first positioning device 12 to mark a target position in the displayed three-dimensional ultrasonic image 162, and generate a first positioning signal 122 accordingly. Please refer to FIGS. 6A-6B , which are schematic diagrams showing the operator using the aforementioned first positioning device 12 for marking. As shown in Fig. 6A, the display device 11 displays a lateral virtual axis 112' and a virtual reference point 114 movable along the lateral virtual axis 112' in the displayed picture (three-dimensional ultrasonic image). As shown in FIG. 6B, the operator can move the virtual reference point 114 to a target position 116 via the aforementioned first positioning device 12; after confirming the target position 116, the first positioning device 12 will generate a first The signal 122 is located and transmitted to the aforementioned automatic displacement device 14. In addition to receiving the first positioning signal 122, the automatic displacement device 14 also receives the second positioning signal 152 generated by the second positioning device 15 and according to the received first positioning signal 122 and the second positioning signal 152. The movement of the high-energy focused ultrasonic device 13 is controlled. In the implementation, the virtual axis can also be designed as a movable person; in this example, the operator can also control the movement of the virtual axis by the first positioning device.

In the implementation, as shown in FIG. 4B, the automatic displacement device 14 first moves the ultrasonic scanner 102 of the ultrasonic device 10 to a first position 144 and a third position of the patient's body surface by the robot arm 142. Ultrasonic scanning is performed on 148 to capture a plurality of two-dimensional ultrasonic images 106. After the operator completes the marking of the target position via the first positioning device 12, the automatic displacement device 14 moves the high-energy focusing ultrasonic device 13 to the first positioning signal 122 and the second positioning signal 152. The second position 146 is to direct a focused energy to a location in the patient corresponding to the aforementioned target location. As described above, this embodiment uses a plurality of ultrasonic scanners to perform multi-point simultaneous scanning on a patient, so that it can be treated according to the previous treatment before scanning. The target position is determined by a plurality of positions on the patient's body surface to be simultaneously subjected to ultrasonic scanning, and the configuration of the ultrasonic scanner used is determined according to the anatomy of the ultrasonic scanning position to be performed.

Please refer to FIGS. 8C and 8D, wherein FIG. 8C shows the structure of the ultrasonic transmission medium used in the second embodiment of the high-energy focused ultrasonic therapeutic apparatus of the present invention, and the 8D diagram shows the ultrasonic wave in FIG. 8C. A schematic cross-sectional view of a conductive medium structure taken along line BB'. In the second embodiment, the ultrasonically conductive medium structure is also configured as a wearing member, except that the wearing member 17' is directly made of the solid ultrasonic conducting medium 172.

In addition, the ultrasonic transmission medium structure used in the high-energy focusing ultrasonic therapy device of the present invention can also be configured as a single-cavity or dual-chamber type, and the 9A to 9B-line display a single-chamber ultrasonic transmission medium structure, 10A to 10C show the dual-chamber ultrasonic transmission medium structure.

Fig. 9A is a view showing another embodiment of the structure of the ultrasonic transmission medium used in the high-energy focused ultrasonic therapeutic apparatus of the present invention, and Fig. 9B is a view showing the structure of the ultrasonic conductive medium along the CC' in Fig. 9A. Schematic diagram of the line obtained. In this embodiment, the ultrasonic conductive medium structure is configured as a hollow conducting cabin 18.

As shown in Figures 9A and 9B, the hollow conducting compartment 18 has a cover 184 and defines a space 182 therein for the patient to lie in. In the space 182, an ultrasonic conductive medium 183 sufficient to cover the patient's body is injected; in the case of water, as shown in FIG. 9A, water can be injected into the space 182 through a water inlet 180 before use. After use, the water can be drained through a water outlet 181.

In this embodiment, a plurality of staggered rails 185 are disposed on the inner surface of the cover body 184, and a plurality of seats 186 displaceable on the rails are disposed on the rails 185 for A probe for accommodating a plurality of ultrasonic scanners 102 and high-energy focused ultrasonic devices 132. By this design, the movement of the plurality of ultrasonic scanners 102 and the high-energy focused ultrasonic device probe 132 on the inner surface of the cover 185 can be controlled. In addition, the seat body can be moved along an axis or in a direction away from the inner surface of the cover, in addition to being movable on the track. By rotating, the scanning range of the ultrasonic scanner can be changed; by moving in a direction away from the inner surface of the cover, the problem that the distance between the track and the surface of the ultrasonic conductive medium is too long can be solved. In addition to the above methods, other mechanisms (such as magnetic or electric power) may be used to control the movement of the ultrasonic scanner, the probe of the high-energy focusing ultrasonic device on the inner surface of the cover, or the ultrasonic control of the ultrasonic scanner by the robot arm. The movement in the cabin.

Please refer to FIGS. 10A and 10B, wherein FIG. 10A is a schematic view showing still another embodiment of the structure of the ultrasonic transmission medium used in the high-energy focused ultrasonic therapeutic apparatus of the present invention, and FIG. 10B is a diagram showing the super 10A. A schematic cross-sectional view of the acoustically conductive medium structure taken along the line DD'. In this embodiment, the ultrasonic transmission medium structure is configured as an upright dual-chamber hollow transmission chamber 19. With the dual-chamber design, the patient can stand in the inner compartment, and the ultrasonic scanner can move around the patient in a space outside the inner and outer cabins in a 360-degree space, and the patient is subjected to ultrasonic scanning and High-energy focused ultrasound therapy.

As shown in Figures 10A and 10B, the hollow conducting compartment 19 has an inner compartment 194 and defines a space 192 therein (i.e., a space inside the hollow conducting compartment 19 and outside the inner compartment 194). The inner compartment 194 is constructed of a solid state ultrasonic conducting medium, and a liquid ultrasonic conducting medium 193 (e.g., water) sufficient to cover the patient's body is additionally injected into the inner chamber 194. In addition, as shown in FIG. 10A, the inner compartment 194 is provided with a water inlet 190 and a water outlet 191, so that the liquid ultrasonic conductive medium 193 can be injected into the inner compartment 194 via the water inlet 190 before use. After use, the liquid ultrasonic conducting medium 193 can be discharged through the water outlet 191.

In addition, a plurality of staggered rails 195 are disposed on the inner surface of the hollow conducting compartment 19, and a plurality of seats 196 displaceable on the rails are disposed on the rails 195 for receiving a plurality of The ultrasonic scanner 102 and the probe 132 of the high energy focused ultrasonic device. By this design, a plurality of ultrasonic scanners can be controlled to move on the inner surface of the hollow conducting chamber 19 to pass through the inner chamber into which the liquid ultrasonic medium is injected, and the patient is subjected to ultrasonic scanning and high-energy focused ultrasonic treatment. .

The foregoing track may be disposed outside the inner surface of the hollow conducting compartment, or may be disposed on the outer surface of the inner tank; for example, the track may be constructed in a frame form and coupled to the outer surface of the inner tank, It can be used not only for the ultrasonic scanner but also as an external support structure for the inner compartment. In addition, the seat body can be rotated along an axis or in a direction away from the inner surface of the hollow conductive chamber, in addition to being movable on the track. By rotating, the scanning range of the ultrasonic scanner can be changed; by moving away from the inner surface of the hollow conducting compartment, the problem that the distance between the rail and the inner compartment is too long can be solved. In addition to the above, other mechanisms (such as magnetic force, electric power) may be used to control the movement of the ultrasonic scanner, the high-energy focused ultrasonic device probe on the inner surface of the hollow conducting chamber, or the ultrasonic arm through the robot arm. Move within space 192.

In the implementation, the hollow transmission compartment may be provided with a door for the patient to enter the inner compartment, or designed to be vertically movable relative to a platform, and the patient enters the inner compartment by vertical movement of the hollow conducting compartment. . Please refer to FIG. 10C, which shows a state of use of the structure of the ultrasonic conductive medium in FIG. 10A. As shown, the hollow conducting compartment 19 is designed to be moved into or out of a platform 2. At the beginning, the hollow conducting chamber 19 can be completely moved into the platform 2, and the patient can stand on the platform 3 corresponding to the position of the inner compartment (the foot type mark in Fig. 10A), and then, as needed, The hollow conductive chamber 19 embedded in the interior of the platform is vertically moved up to a preset position (for example, relative to the waist, chest or neck of the patient), and the liquid ultrasonic conductive medium is injected into the inner chamber through the water inlet. Ultrasonic scanning and high-energy focused ultrasound therapy. In this way, in addition to meeting different needs, the height of the hollow conduction chamber removed from the platform can be adjusted according to the height of different patients, and the use is more flexible.

Please refer to Fig. 7, which is a schematic diagram showing another aspect of the use of the virtual axis and the virtual reference point in the high energy focused ultrasonic therapy device of the present invention. As shown, when the captured two-dimensional ultrasonic image or the constructed three-dimensional ultrasonic image is displayed on the display device 11, the display device 11 will display two virtual axes intersecting each other in the displayed image. 112, 112' and a virtual reference point 114 movable along the aforementioned two virtual axes 112, 112'. The operator can move the virtual reference point 114 to a target position via the first positioning device 12; after confirming the target position, the first positioning device 12 generates a first positioning signal 122 accordingly, and transmits the signal to the first positioning device 122. The aforementioned automatic displacement device 14 controls the movement of the high energy focusing ultrasonic device 13. In practice, the two virtual axes intersecting may also be designed as movable; in this example, the operator may control the movement of the virtual axis by the aforementioned first positioning device.

In view of the foregoing, the present invention can indeed achieve the intended purpose, and provides a combination of an ultrasonic imaging device for positioning using only an ultrasonic imaging device, a positioning ultrasonic imaging device for non-coaxial setting, and a high-energy focusing ultrasonic device for treatment. The operator uses the virtual axis and the virtual reference point to mark the target position of the high-energy focused ultrasound therapy device on the screen of the display device. It is extremely valuable for industrial use, and patent applications are filed according to law.

The above description and drawings are merely illustrative of the embodiments of the present invention, and those of ordinary skill in the art can

Claims (7)

A high-energy focused ultrasonic therapy device includes: an ultrasonic imaging device having an ultrasonic scanner for an operator to perform ultrasonic scanning on a first position on a patient's body surface to capture Ultrasonic image; a display device for receiving and displaying the ultrasonic image captured by the ultrasonic imaging device; and a first positioning device for the ultrasonic image displayed by the operator on the display device A target position is indicated in the first position signal, and a second positioning device is configured to detect the orientation of the ultrasonic scanner of the ultrasonic imaging device, and generate a second positioning signal accordingly. And a high-energy focusing ultrasonic device, which receives the first positioning signal generated by the first positioning device and the second positioning signal generated by the second positioning device, and according to the first positioning signal and the second positioning The signal is moved to a second position on the body surface of the aforementioned patient, thereby directing a focused energy to the patient's body corresponding to the aforementioned target position. The high-energy focused ultrasonic therapy device of claim 1, further comprising an image processing device, and the ultrasonic imaging device further comprises another ultrasonic scanner; wherein the other ultrasonic scanner is For the operator to perform ultrasonic scanning on a third position on a patient's body surface to capture an ultrasonic image; the image processing device is configured to process the first position and the third position a supersonic image, and constructing a three-dimensional ultrasonic image corresponding to the internal anatomy of the patient; the display device is for receiving and displaying the three-dimensional ultrasonic image constructed by the ultrasonic imaging device; and the first positioning device Then, the operator is used to mark a target position in the three-dimensional ultrasonic image, and accordingly generate a first positioning signal. A high-energy focused ultrasonic therapy apparatus according to claim 1 or 2, wherein the aforementioned The display device displays a virtual axis and a virtual reference point movable along the virtual axis in the displayed ultrasonic image, for the operator to move the virtual reference point to a target position to generate the first positioning signal. . The high energy focused ultrasonic therapeutic apparatus of claim 3, wherein the virtual axis is a longitudinal central axis. The high energy focused ultrasonic therapy apparatus of claim 3, wherein the virtual axis is a lateral central axis. The high-energy focused ultrasonic therapeutic apparatus according to claim 1 or 2, wherein the display device displays two virtual axes intersecting each other and one along the two virtual axes in the displayed ultrasonic image. Moving the virtual reference point for the operator to move the virtual reference point to a target position to generate the first positioning signal. The high-energy focused ultrasonic therapeutic apparatus according to claim 1 or 2, further comprising: an automatic displacement device that controls the ultrasonic scanner of the ultrasonic imaging device with a robot arm and the aforementioned high-energy focusing type The movement of the ultrasonic device.