CN103520650B - 一种治疗慢性浅表性胃炎的中药 - Google Patents
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Abstract
本发明提供了一种治疗慢性浅表性胃炎的中药，该中药由人参、黄芪、苦参、升麻、柴胡、薏米、甘松、莪术、桃仁、云苓、枳壳、白芥子、茴香十三味药组成。制备方法：按重量份称取各原料，加冷水高于药面浸泡1～1.5小时，大火烧开，小火煮25～35分钟，过滤去渣，得药液；煎两次，将两次的药液混合后再煮沸，小火煮4～5分钟，共煎出400ml，平均分为两份。本发明中药不仅具有疏肝解郁、健脾理气、益气和胃、清热止痛、活血化瘀的功效，还能降低药物的毒性和不良反应，疗程短，效果好，从而达到全面调节恢复胃及肝、脾、肠各种生理功能的目的。
Description
技术领域
本发明涉及中药领域，具体涉及一种治疗慢性浅表性胃炎的中药。
背景技术
慢性浅表性胃炎是胃黏膜呈慢性浅表性炎症的疾病，为消化系统常见病，属慢性胃炎中的一种。可因嗜酒、喝浓咖啡、胆汁反流，或因幽门螺杆菌感染等引起。患者可有不同程度的消化不良症状，如进食后上腹部不适、隐痛，伴嗳气、恶心、泛酸，偶有呕吐。
在我国，胃肠道疾病患病总人数已接近1.3亿人，其中约有40％的患者长期受到胃肠道疾病的困扰，许多人甚至面临着癌变的威胁。对于慢性浅表性胃炎的药物治疗上，一般采用保护胃黏膜药、调整胃肠运动功能药物、抗生素、制酸剂等，但这类药物不能给予慢性浅表性胃炎患者满意的治疗效果，同时，对肝、肾等器官的副作用大，这类药物的耐药性问题也极大限制了其发展。而中药在改善症状，修复胃粘膜有不同于现代医学的优势，症状消失快，粘膜修复好，药物无任何不良反应。
发明内容
本发明的目的在于提供一种治疗慢性浅表性胃炎的中药，以克服现有技术中治疗慢性浅表性胃炎的药副作用大、疗效单一、效果差的缺陷。
为了实现上述目的，本发明技术方案是：
一种治疗慢性浅表性胃炎的中药，由以下重量份的原料药制成：人参8～12份，黄芪28～32份，苦参13～17份，升麻13～16份，柴胡14～18份，薏米28～33份，甘松13～17份，莪术8～12份，桃仁12～18份，云苓27～31份，枳壳8～12份，白芥子14～18份，茴香3～7份。
一种优化方案，所述中药由以下重量份的原料药制成：人参10份，黄芪30份，苦参15份，升麻15份，柴胡15份，薏米30份，甘松15份，莪术10份，桃仁15份，云苓30份，枳壳10份，白芥子15份，茴香5份。
另一种优化方案，所述中药由以下重量份的原料药制成：人参9份，黄芪31份，苦参16份，升麻14份，柴胡16份，薏米31份，甘松14份，莪术9份，桃仁13份，云苓28份，枳壳11份，白芥子16份，茴香4份。
再一种优化方案，所述中药由以下重量份的原料药制成：人参11份，黄芪29份，苦参14份，升麻13份，柴胡16份，薏米29份，甘松16份，莪术11份，桃仁14份，云苓29份，枳壳9份，白芥子17份，茴香6份。
进一步的优化方案，所述中药由以下重量份的原料药制成：人参10份，黄芪28份，苦参13份，升麻16份，柴胡17份，薏米32份，甘松14份，莪术8份，桃仁16份，云苓27份，枳壳12份，白芥子14份，茴香6份。
制备方法：按重量份称取各原料，加冷水高于药面浸泡1～1.5小时，大火烧开，小火煮25～35分钟，过滤去渣，得药液；煎两次，将两次的药液混合后再煮沸，小火煮4～5分钟，共煎出400ml，平均分为两份。
治疗方法：每天早晚各一次，饭后服用，每次服用一份，即一天一剂，五至十天一个疗程。
禁忌：服药期间禁食辛辣刺激之物。
下面对本发明采用的各原料药的药性进行简要说明：
人参：性平，味甘，微苦，微温。归脾、肺、心经。大补元气，复脉固脱，补脾益肺，生津止渴，安神益智。用于劳伤虚损、食少、倦怠、反胃吐食、大便滑泄、虚咳喘促、自汗暴脱、惊悸、健忘、眩晕头痛、阳痿、尿频、消渴、妇女崩漏、小儿慢惊及久虚不复，一切气血津液不足之症。
黄芪：味甘，微温。归肺、脾、肝、肾经。有益气固表、敛汗固脱、托疮生肌、利水消肿之功效。用于治疗气虚乏力，中气下陷，久泻脱肛，便血崩漏，表虚自汗，痈疽难溃，久溃不敛，血虚萎黄，内热消渴，慢性肾炎，蛋白尿，糖尿病等。炙黄芪益气补中，生用固表托疮。
苦参：味苦，性寒。归肝、肾、大肠、小肠、膀胱、心经。清热燥湿，祛风杀虫。主湿热泻痢，肠风便血，黄疸，小便不利，水肿，带下，阴痒，疥癣，麻风，皮肤瘙痒，湿毒疮疡。
升麻：辛、微甘，微寒。发表透疹，清热解毒，升举阳气。主治风热头痛，齿痛，口疮，咽喉肿痛，麻疹不透，阳毒发斑；脱肛，子宫脱垂。
柴胡：性微寒、味苦、辛。归肝、胆经，具疏肝利胆、疏气解郁、散火之功效。透表泄热，疏肝解郁，升举阳气。主治感冒发热、寒热虚劳发热。小儿痘疹余热，面黄肌瘦腹部膨大，疟疾，肝郁气滞，胸肋胀痛，脱肛，子宫脱落，月经不调。
薏米：味甘、淡，性凉。归脾、肺、肾经。具有利水、健脾、除痹、清热排脓的功效。用于小便不利、水肿、脚气、脾虚泄泻，也可用于肺痈、肠痈等病的治疗。尚用于胃癌、子宫颈癌、绒毛膜上皮癌等癌症以及多发性疣。
甘松：味辛、甘、温。归脾、胃经。行气止痛，开郁醒脾，外用祛湿消肿。用于中焦寒凝气滞，脾胃不和，食欲不振，呕吐；外用治牙痛。
莪术：辛、苦，温。归肝、脾经。行气破血，消积止痛。用于燀瘕痞块，瘀血经闭，食积胀痛；早期宫颈癌。
桃仁：苦、甘，平。归心、肝、大肠经。活血祛瘀，润肠通便，止咳平喘。用于经闭，痛经，癓瘕痞块，跌扑损伤，肠燥便秘。
云苓：性味甘、淡，平。归心、肺、脾、肾经。利水，渗湿利尿。主治小便不利，水肿胀满，痰饮咳逆，呕吐，脾虚食少，泄泻，心悸不安，失眠健忘，遗精白浊。
枳壳：破气，行痰，消积。治胸膈痰滞，胸痞，胁胀，食积，噫气，呕逆，下痢后重，脱肛，子宫脱垂。
白芥子：无臭，味辛、辣。《得配本草》：“入手太阴经。”温肺豁痰利气，散结通络止痛。用于咳喘痰多，胸满胁痛，肢体麻木，关节肿痛，湿痰流注，阴疽肿毒，胸胁胀满疼痛，反胃呕吐，中风不语，肢体痹痛麻木，脚气，跌打肿痛。
茴香：散寒止痛，理气和胃。用于寒疝腹痛，睾丸偏坠，痛经，少腹冷痛，脘腹胀痛，食少吐泻，睾丸鞘膜积液。盐小茴香暖肾散寒止痛。用于寒疝腹痛，睾丸偏坠，经寒腹痛。
慢性浅表性胃炎的发病机理比较复杂，病在胃而涉及脾、肝、大肠、小肠。按照中医学理论，脾胃属土，同居中焦；脾气的特点以升为顺，胃气的特点以降为和，二者经脉互相络属，配合成脏腑阴阳表里关系；脾主运化转输，胃主受纳腐熟；脾主升清，以升为顺。胃的消化、传导要靠肝气的疏泄，如果肝气犯胃，则肝胃不和，气滞血瘀，食滞胃脘。如肠道功能紊乱，肠道容易痉挛、积气无法排出，造成胃脘痛、胀痛等胃部病症。
本发明采用以上技术方案后，与现有技术相比，具有如下优点：本发明按照中医胃病发病机理、利用不同组分药物的相互作用关系，十三味药物科学组方，其有效成分通过人体的吸收，能快速消炎、杀菌，加快胃的血液循环、修复受损的胃组织细胞，同时调理脾、肝、肠道的功能，从而达到治疗的目的。本发明的独特之处在于，本发明中药不仅具有疏肝解郁、健脾理气、益气和胃、清热止痛、活血化瘀的功效，还能降低药物的毒性和不良反应，疗程短，效果好，从而达到全面调节恢复胃及肝、脾、肠各种生理功能的目的。
具体实施方式
实施例1：一种治疗慢性浅表性胃炎的中药，由以下重量份的原料药制成：人参10份，黄芪30份，苦参15份，升麻15份，柴胡15份，薏米30份，甘松15份，莪术10份，桃仁15份，云苓30份，枳壳10份，白芥子15份，茴香5份。
实施例2：一种治疗慢性浅表性胃炎的中药，由以下重量份的原料药制成：人参9份，黄芪31份，苦参16份，升麻14份，柴胡16份，薏米31份，甘松14份，莪术9份，桃仁13份，云苓28份，枳壳11份，白芥子16份，茴香4份。
实施例3：一种治疗慢性浅表性胃炎的中药，由以下重量份的原料药制成：人参11份，黄芪29份，苦参14份，升麻13份，柴胡16份，薏米29份，甘松16份，莪术11份，桃仁14份，云苓29份，枳壳9份，白芥子17份，茴香6份。
实施例4：一种治疗慢性浅表性胃炎的中药，由以下重量份的原料药制成：人参10份，黄芪28份，苦参13份，升麻16份，柴胡17份，薏米32份，甘松14份，莪术8份，桃仁16份，云苓27份，枳壳12份，白芥子14份，茴香6份。
上述4个实施例中的中药制备方法均相同。
制备方法：按重量份称取各原料，加冷水高于药面浸泡1～1.5小时，大火烧开，小火煮25～35分钟，过滤去渣，得药液；煎两次，将两次的药液混合后再煮沸，小火煮4～5分钟，共煎出400ml，平均分为两份。
治疗方法：每天早晚各一次，饭后服用，每次服用一份，即一天一剂，五至十天一个疗程。
禁忌：服药期间禁食辛辣刺激之物。
对比试验：取500例慢性浅表性胃炎患者，随机选取400例作为治疗组，另外100例作为对照组，其中400例患者分为试验组1、实验组2、实验组3和实验组4，每个实验组治疗随机抽取的100例患者，试验组1使用本发明实施例1制备的中药；试验组2使用本发明实施例2制备的中药；试验组3使用本发明实施例3制备的中药；试验组4使用本发明实施例4制备的中药。将按上述制备方法熬制好的中药分别给上述实验组患者按上述服用方法服用，十天一个疗程。
对照组按照常规的治疗方法，硫糖铝、雷尼替丁、颠茄片口服。
辅以胃镜和幽门螺杆菌检查。
一个疗程后的治疗结果对比情况如下表：
| 组别 | 显效(例) | 有效(例) | 无效(例) | 总有效率(％) |
| 试验组1 | 89 | 10 | 1 | 99 |
| 实验组2 | 86 | 12 | 2 | 98 |
| 实验组3 | 85 | 11 | 4 | 96 |
| 试验组4 | 84 | 13 | 3 | 97 |
| 对照组 | 80 | 10 | 10 | 90 |
从以上数据可以看出，使用本发明五个实施例制备的药物治疗慢性浅表性胃炎，本发明四个实施例制备的药物的有效率均比对照组常规治疗的有效率高，平均有效率达到97.5％，其中实施例1的效果最好。
典型病例：
病例1：王某，男，20岁，患有胃病半年，胆汁返流，幽门发炎，饭后胀，长时间不消化，嗳气，确诊为慢性浅表性胃炎，服用本发明的中药(按实施例1中药组份制得)，仅五天(一个疗程)就见效，十天症状消失。继续巩固服用两个疗程，痊愈。半年后随访，无复发。
病例2：赵某，女，47岁，胃部不适1年，隐隐作痛，无规律，经常感觉肚子饿，食则饱，反酸，胃镜显示主要是胃窦部红肿，充血，有小点糜烂，确诊为慢性浅表性胃炎。服用本发明的中药(按实施例2中药组份制得)，十天(一个疗程)就见效，二十天症状消失。继续巩固服用三个疗程，痊愈。八个月后随访，无复发。
病例3：李某，男，60岁，胃部不适已有6年，胸闷嗳气，激动则胃脘胀痛，便秘，反酸，恶心，确诊为慢性浅表性胃炎。服用本发明的中药(按实施例4中药组份制得)，二十天(两个疗程)见效，四十天症状消失。继续巩固服用四个疗程，痊愈。1年后随访，无复发。
以上所述仅为本发明的较佳实施例而已，并不用以限制本发明，凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。
Claims (5)
1.一种治疗慢性浅表性胃炎的中药，其特征在于：它的活性成分由以下重量份的原料药制成：人参8～12份，黄芪28～32份，苦参13～17份，升麻13～16份，柴胡14～18份，薏米28～33份，甘松13～17份，莪术8～12份，桃仁12～18份，云苓27～31份，枳壳8～12份，白芥子14～18份，茴香3～7份。
2.如权利要求1所述的治疗慢性浅表性胃炎的中药，其特征在于：它的活性成分由以下重量份的原料药制成：人参10份，黄芪30份，苦参15份，升麻15份，柴胡15份，薏米30份，甘松15份，莪术10份，桃仁15份，云苓30份，枳壳10份，白芥子15份，茴香5份。
3.如权利要求1所述的治疗慢性浅表性胃炎的中药，其特征在于：它的活性成分由以下重量份的原料药制成：人参9份，黄芪31份，苦参16份，升麻14份，柴胡16份，薏米31份，甘松14份，莪术9份，桃仁13份，云苓28份，枳壳11份，白芥子16份，茴香4份。
4.如权利要求1所述的治疗慢性浅表性胃炎的中药，其特征在于：它的活性成分由以下重量份的原料药制成：人参11份，黄芪29份，苦参14份，升麻13份，柴胡16份，薏米29份，甘松16份，莪术11份，桃仁14份，云苓29份，枳壳9份，白芥子17份，茴香6份。
5.如权利要求1所述的治疗慢性浅表性胃炎的中药，其特征在于：它的活性成分由以下重量份的原料药制成：人参10份，黄芪28份，苦参13份，升麻16份，柴胡17份，薏米32份，甘松14份，莪术8份，桃仁16份，云苓27份，枳壳12份，白芥子14份，茴香6份。
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