CN103520466A

CN103520466A - Traditional Chinese medicine decoction for treating diabetic constipation

Info

Publication number: CN103520466A
Application number: CN201310473812.3A
Authority: CN
Inventors: 马兆强; 张丽香
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-09-24
Filing date: 2013-09-24
Publication date: 2014-01-22
Anticipated expiration: 2033-09-24
Also published as: CN103520466B

Abstract

The invention relates to the field of pharmaceutical formula, and in particular to a traditional Chinese medicine decoction for treating diabetic constipation. The invention has the technical characteristic that the decoction comprises the following raw materials by weight: 12-23 parts of Radix Ophiopogonis, 12-22 parts of bitter orange, 8-10 parts of Semen Trichosanthis, 12-16 parts of banksia rose, 4-6 parts of rhubarb, 10-14 parts of citron, 10-12 parts of bitter orange, 8-10 parts of licorice, 2-3 parts of folium sennae, 4-6 parts of dens draconis, 12-16 parts of cassia twig, 8-12 parts of Ligusticum wallichii and 6-10 parts of gentian. The above 13 bulk drugs are immersed with water, decocted and deslagged to obtain a filtrate. The decoction provided by the invention has curative effect, low cost and no toxic or side effect, and is used for the treatment of diabetic constipation.

Description

The Chinese medicine decoction for the treatment of diabetic constipation

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine decoction that is used for the treatment of diabetic constipation.

Background technology

As everyone knows, along with people living condition's improvement, the change of life style, the sickness rate of diabetes and complication raises day by day, diabetic gastrointestinal disease is the common chronic complicating diseases of diabetes, prevalence is 30%-76%, and the constipation common sympton that is diabetes gastrointestinal disease accounts for 60%, its pathogenesis still imperfectly understands, may be due to hyperglycemia and Developmental and Metabolic Disorder, cause neural malnutrition, domination gastrointestinal nerve damage.

Western medicine there is no specific treatment ways and means at present, conventional symptomatic treatment medicine: cisapride sheet, phenolphthalein tablets etc., but the reactions such as some patients were has dizziness, distending pain in the head, drowsiness, tongue is numb, abdominal discomfort, arrhythmia, can not tolerate, once the Case report that had gynecomasty, galactorrhea, convulsibility epilepsy, the extrapyramidal symptoms and frequent micturition, limited its clinical practice, the people's health in serious threat, and quality of life is declined comprehensively.

Summary of the invention

Object of the present invention is exactly in order to overcome above-mentioned existing technical deficiency, and a kind of determined curative effect is provided, with low cost, the Chinese medicine decoction of the treatment diabetic constipation having no side effect.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine decoction for the treatment of diabetic constipation, and its technical characterictic is that raw material forms to be counted with weight portion: Radix Ophiopogonis 12～23, Fructus Aurantii Immaturus 12～22, Semen Trichosanthis 8～10, the Radix Aucklandiae 12～16, Radix Et Rhizoma Rhei 4～6, citron 10～14, Fructus Aurantii Immaturus 10～12, Radix Glycyrrhizae 8～10, Folium Sennae 2～3, Dens Draconis 4～6, Ramulus Cinnamomi 12～16, Rhizoma Chuanxiong 8～12, Radix Gentianae 6～10, above-mentioned 13 taste crude drug are soaked in water, the filtrate of removing slag to obtain after decocting.

The invention has the beneficial effects as follows, determined curative effect, with low cost, have no side effect.

The specific embodiment

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1:

Adopt Radix Ophiopogonis, Fructus Aurantii Immaturus, Semen Trichosanthis, the Radix Aucklandiae, Radix Et Rhizoma Rhei, citron, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Folium Sennae, Dens Draconis, Ramulus Cinnamomi, Rhizoma Chuanxiong, Radix Gentianae is that raw material is prepared from, its component (weight portion) is Radix Ophiopogonis 17, Fructus Aurantii Immaturus 17, Semen Trichosanthis 9, the Radix Aucklandiae 14, Radix Et Rhizoma Rhei 4, citron 12, Fructus Aurantii Immaturus 11, Radix Glycyrrhizae 9, Folium Sennae 2, Dens Draconis 6, Ramulus Cinnamomi 14, Rhizoma Chuanxiong 10, Radix Gentianae 9, get 180 grams of mixing of above-mentioned 13 kinds of crude drug gross weights, by clean water, soak 1 hour, water consumption 1200ml, after intense fire is fried open, use slow fire boiling instead, extracting juice 200ml, two decoct and add water 300ml, decocting extracting juice 200ml, two decoct mixing, decoct again and be concentrated into 300ml, sterile vacuum packing, preparation gets product.Every day potion divide 2 times oral, each (medicine) being taken before meal 150ml sooner or later.Within 10 days, be a course for the treatment of, each course for the treatment of is every three days, takes continuously three courses for the treatment of of decoction of the present invention.

Therapeutic Principle of the present invention: diabetic constipation belongs to the constipation category that the traditional Chinese medical science is quenched one's thirst in deteriorated case, the scorching blood stasis of deficiency of qi and yin is the important pathogenesis, runs through primary disease all the time.Diabetic constipation be the course of disease with the passing of time, more very, cloudy body fluid deficiency is empty for the scorching blood stasis of deficiency of qi and yin, large intestine not flourish and conduct unable due to, its pathogenesis is the cloudy body fluid deficiency of gas, dryness of the intestine blood stasis, therefore treatment take supplementing QI and nourishing YIN, moisturize purge heat, blood circulation promoting and blood stasis dispelling is rule.In component of the present invention: Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation; Radix Et Rhizoma Rhei stasis removing, relieving constipation by purgation, stagnant for Gastrointestinal excess heat, constipation; In Fructus Aurantii Immaturus is stagnant, stop, feeling of fullness distending pain, constipation, heavy after dysentery, blocked-up chest, gastroptosis, uterine prolapse, proctoptosis; Semen Trichosanthis enters lung meridian, sweet cold clear and rich, reduces phlegm and purges heat, for controlling the key medicine of heat-phlegm dry phlegm.Enter stomach, large intestine channel, matter profit greasiness, loosening bowel to relieve constipation, controls again dryness of the intestine constipation; The Radix Aucklandiae is for turbid damp retardance mechanism of qi, and chest and diaphragm painful abdominal mass is vexed, abdominal distention, and vomiting is felt sick, and belch is indigestion and loss of appetite; Citron has the effect of activating QI to eliminate phlegm, analgesic antiphlogistic; In Fructus Aurantii Immaturus is stagnant, stop to weigh thoracic obstruction puerperal abdonimal pain after feeling of fullness distending pain constipation dysentery; Folium Sennae is used for purging heat capable stagnant, relieving constipation, diuretic.Stagnant for accumulation of heat, constipation stomachache, edema distension; The effect of Radix Glycyrrhizae grass has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle skin ulcer; Dens Draconis be ancient times mammal as if the fossil of the tooth of class, rhinoceros class, Hippocampal cortex etc., tranquillizing the mind by relieving convulsion, heat clearing away and restlessness relieving.Control infantile convulsion demented, dysphoria with smothery sensation is uneasy, insomnia and dreamful sleep; Ramulus Cinnamomi is the withe of canella Cortex Cinnamomi.Acrid, sweet, warm.Enter the heart, lung, urinary bladder channel.There is relieving the exterior syndrome by diaphoresis, promoting the flow of QI-blood by warming the meridian, the effect of activating YANG and prormoting functioning of QI; The various diseases of the suitable stagnation of blood stasis of Rhizoma Chuanxiong; Wind-expelling pain-stopping, effectiveness is excellent, can control wind syndrome of head headache, rheumatic arthralgia etc.; Radix Gentianae nature and flavor are bitter, puckery, Great Cold, nontoxic.Cure mainly cold and heat between bone, frightened pathogenic factor gas, the wound absolutely that continues, determines the five internal organs, parasite killing poison.All medicines share profit and do not grow greasy, cool and impairment of YIN not, supplementing QI and nourishing YIN, blood stasis dispelling intestine moistening, makes three warmers fluent, constipation is dredged and is separated.The present invention has adjusting gastrointestinal function, promotes enterokinesia, and constipation relieving symptom simultaneously can the effect of auxiliary adjustment blood glucose, and clinical practice treatment diabetic constipation is obtained good efficacy.

The embodiment that each raw material of the present invention also can the listed ratio of according to the form below (unit: gram) mixes realizes.Its processing technique is identical with embodiment 1.

The clinical preliminary test carrying out below in conjunction with Wendeng City, Wo Yuan，Ji In Shandong Weihai central hospital is done further, is described in detail the present invention:

1, case selection: this organizes 60 examples, male 32 examples, female's 28 examples, age 2l-64 year, 40 years old mean age, course of disease 2-27, average 10.2 years.

2, Therapeutic Method: early, late twice (medicine) being taken before meal, each oral a bag 10 days is a course for the treatment of, and every three days, take continuously three courses for the treatment of of the present invention each course for the treatment of.

3, diagnostic criteria: observe case diabetes diagnosis standard and all meet the diagnostic criteria that WHO proposed in 1997, and there is defecation in various degree to require great effort, constipation with dry stool, the clinical manifestations such as defecation frequency minimizing, get rid of the serious heart, brain, kidney complication, colon, rectum organic disease are got rid of in the barium enema of x line, and Metcalf improves and simplifies technical measurement Colonic transit time (CTT) all over upper limits of normal 56 hours.

4, criterion of therapeutical effect: formulate with reference to relevant criterion in " traditional Chinese medical science disease Standardization of diagnosis and curative effect " and " new Chinese medicine guideline of clinical investigations (trying) ".Cure: in two days, once, just matter turns profit to defecation, solution is unobstructed just time, and short-term is without recurrence.Effective: in three days, once, just matter turns profit to defecation, it is smooth that solution is just owed.Do not heal: symptom is not improved or recurs and even increase the weight of during treating.

5, therapeutic outcome: the present invention treats 60 examples, takes medicine three courses for the treatment of, cures 14 examples, effective 42 examples, invalid 4 examples, cure rate 23%, effective percentage 70%, inefficiency 7%, total effective rate 93%.

Claims

1. treat a Chinese medicine decoction for diabetic constipation, its technical characterictic is: raw material forms to be counted with weight portion, Radix Ophiopogonis 12～23, Fructus Aurantii Immaturus 12～22, Semen Trichosanthis 8～10, the Radix Aucklandiae 12～16, Radix Et Rhizoma Rhei 4～6, citron 10～14, Fructus Aurantii Immaturus 10～12, Radix Glycyrrhizae 8～10, Folium Sennae 2～3, Dens Draconis 4～6, Ramulus Cinnamomi 12～16, Rhizoma Chuanxiong 8～12, Radix Gentianae 6～10, above-mentioned 13 taste crude drug are soaked in water, the filtrate of removing slag to obtain after decocting.