CN103520288A - External drug for treating heart disease and vasculitis, and its application - Google Patents
External drug for treating heart disease and vasculitis, and its application Download PDFInfo
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Abstract
An external drug for treating heart disease and vasculitis comprises Semen Momordicae, Semen Pharbitidis and pepper as effective components, also comprises almond, and has the efficacies of channel warming, cold dispelling, blood circulation invigorating, blood stasis removing, cough relieving, calming panting, swelling eliminating, pain relieving, water dispelling and bowel relaxing. The external drug has substantial treatment effects on chronic cardiac insufficiency, arrhythmias, the coronary heart disease, angina, myocardial infarction, the rheumatic heart disease, vasculitis, the pulmonary heart disease, diabetes and phlebitis, and has no toxic side effects. The external drug can also be used for the auxiliary treatment of femur head necrosis and the prevention of the diabetes by reducing the blood sugar value, and has good curative effects on asthma, emphysema, bronchitis and bronchiectasis. After the external drug is applied, the blood quality is obviously improved, microcirculation is improved, and healthy qi is strengthened, thereby above diseases are fundamentally treated. The external drug has the advantages of easy accept, use convenience, no damages to the liver or kidney, definite therapeutic effect, no recurrence, easy obtaining and easy preparation.
Description
Technical field
The present invention relates to tcm field, particularly relate to a kind of treat heart disease, vasculitic medicine for external use and application thereof.
Background technology
Heart disease, vasculitis are clinical common chronic diseases, heavy when light during conditions of patients, are difficult for thoroughly curing.
Chinese medicine heart disease, vasculitis have its advantage, because containing Semen Momordicae, Semen Pharbitidis, Fructus Piperis, Semen Armeniacae Amarum in component of the present invention, applicant has retrieved Chinese medicine patent, find patent documentation as the patent No. be cardiopathic medicine of 200410010299 treatment and preparation method thereof, with Fructus Crotonis, Semen Armeniacae Amarum, Semen Persicae, dry (life) Rhizoma Zingiberis Recens, Tremella, Radix orixae japonicae, form, treatment heart disease is also prevented pulmonary heart disease.
The patent No. is 200510003189.0 1 kinds of Miao Ethnomedicine and preparation and usings method for the treatment of pulmonary tuberculosis and rheumatic heart disease, Semen Persicae, Semen Armeniacae Amarum, Fructus Crotonis, Radix orixae japonicae, Auricularia, Rhizoma Zingiberis Recens, consists of, and is used for the treatment of pulmonary tuberculosis, rheumatic heart disease.
The patent No. is the liniment of 200710015824.6 treatment infantile pneumonias, bronchitis and asthma, consists for the treatment of infantile pneumonia, bronchitis and asthma Semen Persicae, Semen Armeniacae Amarum, Pheretima, Radix Asteris, Radix orixae japonicae, Oryza glutinosa.
The patent No. is hypertensive external used medicine of 200810141099.1 treatment and preparation method thereof, forms treatment hypertension, heart disease with Fructus Crotonis, Semen Momordicae, Semen Persicae, Semen Cassiae, Fructus Crataegi, Spica Prunellae, Fructus Corni, Rhizoma Chuanxiong, Radix orixae japonicae.
The patent No. is 200610045313.4 1 kinds for the treatment of vasculitiss, phlebitic Chinese medicine composition, consists for the treatment of vasculitis, phlebitis Semen Armeniacae Amarum, Semen Momordicae, Radix orixae japonicae, cock bile.
Application number is 200,810,016,997 1 kinds of externally-applied medicinal compositions for the treatment of allergic asthma, consists for the treatment of allergic asthma Semen Pharbitidis, Semen Pharbitidis, Radix orixae japonicae, Semen Momordicae.
Application number is 200810159970.0 1 kinds of Chinese medicine compositions for the treatment of diabetes, consists for the treatment of diabetes Semen Momordicae, Semen Pharbitidis, Semen Pharbitidis, Radix orixae japonicae, raw egg.
Application number is 200810160531.1 1 kinds of cataplasm of tcm for the treatment of diabetes, by Semen Pharbitidis, Radix orixae japonicae, Semen Momordicae, egg, is that raw material forms, and can effectively fall glycopenia therapeutic diabetes.
Application number is 20101220269.2 to have the medicine for external use of hypoglycemic effect, Semen Momordicae, Semen Pharbitidis, the Radix Astragali, Carapax et Plastrum Testudinis, Radix Glycyrrhizae, Fructus Schisandrae Chinensis, Radix Rehmanniae, atractylodes japonica, Radix Pseudostellariae, Fructus Psoraleae, Semen Ginkgo, Radix orixae japonicae, consists of, and prevents and treat diabetes.
Above patent all contains two kinds or several Chinese medicines in Semen Momordicae, Semen Pharbitidis, Semen Pharbitidis, Semen Armeniacae Amarum, Radix orixae japonicae, be used for the treatment of heart disease, pulmonary heart disease, bronchitis, asthma, vasculitis, phlebitis, diabetes effect remarkable, prompting is used these diseases of above treatment by Chinese herbs to have its strong point, but above patent is different from overall composition of the present invention, using method, goal of the invention.
The artificial application of application the present invention has consulted a large amount of medical books and patent documentation, does not find as effective ingredient, to treat heart disease, vasculitic medicine for external use by Semen Momordicae, Semen Pharbitidis, Semen Armeniacae Amarum, Fructus Piperis.
Summary of the invention
The object of this invention is to provide and a kind ofly by Semen Momordicae, Semen Pharbitidis, Fructus Piperis, as effective ingredient, formed, treatment heart disease, vasculitic medicine for external use.The present patent application is dividing an application of application number 201110213234.0.
Another object of the present invention be to provide above-mentioned medicine for external use treatment chronic cardiac insufficiency, arrhythmia (comprise bradycardia, overrun, premature beat, atrial fibrillation, chamber are flutterred, conduction block, fibrillation.), coronary heart diseases and angina pectoris, myocardial infarction, rheumatic heart disease, pulmonary heart disease, diabetes, vasculitis, phlebitis, the application in femur head necrosis medicine, and there is the application in diabetes in treatment asthma, emphysema, bronchitis, bronchiectasis and the prevention of reduction blood glucose value.
The present invention is on the basis of secret prescription handed down in the family from generation to generation, through inventor concentrate on studies for a long time, clinical practice draws, applicant uses so far from research in 1994, in clinical practice, find, in the cardiopathic while for the treatment of, diabetes, vasculitis, phlebitis, femur head necrosis are also had to good therapeutic effect, through repetition learning research Diagnostics of Chinese Medicine, Chinese materia medica, pharmacology of Chinese materia medica, in conjunction with modern medicine report, and clinical practice obtains the present invention eventually.
Medicine for external use of the present invention is comprised of as effective ingredient Semen Momordicae, Semen Pharbitidis, Fructus Piperis, and the component of medication is that inventor draws according to more than ten years clinical empirical summary, and its weight portion is 1.5～15 parts of Semen Momordicaes, 1～15 part of Semen Pharbitidis, 1～6 part, Fructus Piperis.Wherein also add Semen Armeniacae Amarum to form as effective ingredient, its weight portion is 1.5～15 parts of Semen Momordicaes, 1～15 part of Semen Pharbitidis, 1～6 part, Fructus Piperis, 1～9 part, Semen Armeniacae Amarum.
Wherein, Semen Momordicae: bitter micro-sweet, temperature, enters liver, spleen, stomach warp.Dispersing swelling and dissipating binds, toxic removing.It is hot and suffocating and be gout paralysis, migratory arthralgia, flaccidity with cold limbs, beriberi, contraction disease, crane knee joint that " it is former that book on Chinese herbal medicine is asked " controls all cold-damp." Bencao Jingshu " is for loose heat in blood, except the key medicine of carbuncle poison.The Gan Wenneng meridians that pass through, heat in blood is loose, and the loose all cards of heat in blood are recover invariably." Chinese medicine voluminous dictionary " Shanghai science tech publishing house
Semen Pharbitidis: hardship, cold.Return large intestine, lung, kidney channel.The detumescent of relieving oedema or abdominal distension through diuresis or purgation is rushed down drink, capture stagnant, diuresis, ascarifuge.
Fructus Piperis: pungent, heat.Return spleen, stomach, large intestine channel.Warming spleen and stomach for dispelling cold, pain relieving.
Semen Armeniacae Amarum: hardship, tepor.Return lung, large intestine channel.Relieving cough and asthma, loosening bowel to relieve constipation.Below all come from China Traditional Chinese Medicine Publishing House " Chinese materia medica () "
Medicine for external use of the present invention has the effect of dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, relieving cough and asthma, reducing swelling and alleviating pain, the relieving constipation of relieving oedema or abdominal distension through diuresis or purgation.The present invention can be used for treating chronic cardiac insufficiency, arrhythmia (comprise bradycardia, overrun, premature beat, atrial fibrillation, chamber are flutterred, conduction block, fibrillation.), coronary heart diseases and angina pectoris, myocardial infarction, rheumatic heart disease, asthma, pulmonary heart disease, emphysema, bronchitis, bronchiectasis heart and lung diseases, diabetes, vasculitis, phlebitis, effect is remarkable, without any side effects.Also can be used for the auxiliary treatment of femur head necrosis and reduce blood glucose value prevention diabetes occur.Stick the present invention and can obviously improve blood quality, improve immunity, reinforcing body resistance, blood circulation promoting is accelerated, and relief of symptoms, recovers body function rapidly, fundamentally cures above disease.
The present invention can be used alone or coordinates other therapies to use according to state of an illness weight simultaneously.At disease acute attack stage, when using other therapies, external application the present invention can obviously improve curative effect, shortens the course of disease, cures in early days, plays synergistic function; Early stage or catabasis of the state of an illness, uses that energy prevent disease of the present invention occurs, recurrence, development, and progressively healing.Use the present invention should be in line with symptomatic treatment in acute condition, slow ask its principle, in conjunction with Chinese and western medicine advantage, coordinate traditional therapy, can obviously strengthen therapeutic effect, shorten the course of disease, raising cure rate.
The invention has the beneficial effects as follows by liniment of acupuncture point and treat disease, need not take orally, to liver, kidney not damaged, treating both the principal and secondary aspects of a disease, be more afterwards difficult for recurrence, and there is the acceptance of being easy to, the advantages such as easy to use, determined curative effect is stable lastingly, medicine is easy to get, cost is low, easy preparation.
The specific embodiment
By the following examples, the present invention is described in further detail, embodiment is only indicative, the present invention includes but be not limited to following examples, also never mean it by any way or form limit the scope of the invention, do not departing under the technology of the present invention state of mind, the various replacements of making according to ordinary skill knowledge and habitual means or the modification of change, include within the scope of the invention.
The present invention is by Semen Momordicae, Semen Pharbitidis, Fructus Piperis as effective ingredient, and its weight portion is 1.5～15 parts of Semen Momordicaes, 1～15 part of Semen Pharbitidis, 1～6 part, Fructus Piperis.
Embodiment 1 Semen Momordicae 3g, Semen Pharbitidis 1g, Fructus Piperis 3g.
Embodiment 2 Semen Momordicae 6g, Semen Pharbitidis 8g, Fructus Piperis 1g.
Embodiment 3 Semen Momordicae 9g, Semen Pharbitidis 15g, Fructus Piperis 6g.
Embodiment 4 Semen Momordicae 13g, Semen Pharbitidis 10g, Fructus Piperis 5g.
Embodiment 5 Semen Momordicae 15g, Semen Pharbitidis 9g, Fructus Piperis 4g.
Embodiment 6 Semen Momordicae 3g, Semen Pharbitidis 2g, Fructus Piperis 2g.
Above embodiment is all by each medicine taken amount, and pulverization, crosses 80～120 mesh sieves altogether, mixes and get final product.
Wherein also add Semen Armeniacae Amarum as effective ingredient, its weight portion is 1.5～15 parts of Semen Momordicaes, 1～15 part of Semen Pharbitidis, 1～6 part, Fructus Piperis, 1～9 part, Semen Armeniacae Amarum.
Embodiment 1 Semen Momordicae 7g, Semen Pharbitidis 2g, Fructus Piperis 1g, Semen Armeniacae Amarum 1g.
Embodiment 2 Semen Momordicae 5g, Semen Pharbitidis 4g, Fructus Piperis 2g, Semen Armeniacae Amarum 5g.
Embodiment 3 Semen Momordicae 10g, Semen Pharbitidis 10g, Fructus Piperis 6g, Semen Armeniacae Amarum 3g.
Embodiment 4 Semen Momordicae 15g, Semen Pharbitidis 1g, Fructus Piperis 5g, Semen Armeniacae Amarum 8g.
Embodiment 5 Semen Momordicae 3g, Semen Pharbitidis 15g, Fructus Piperis 4g, Semen Armeniacae Amarum 9g.
Embodiment 6 Semen Momordicae 1.5g, Semen Pharbitidis 1g, Fructus Piperis 1g, Semen Armeniacae Amarum 1g.
Above embodiment is all by each medicine taken amount, and pulverization, crosses 80～120 mesh sieves altogether, mixes and get final product.
Using method: get it filled that powder is clear with suitable quantity of water, wine or ethanol, vinegar, raw egg, any is mixed well among peeling raw egg or raw bile, coated appointment acupuncture point and arch of the foot, or external application affected part, 4～24 hours, one pair of company applies 3 times, and interval is applied afterwards next for 4 days and paid, and connecting deposited 4 pairs is a course for the treatment of.
The present invention improves and gets through inventor on the secret prescription handed down in the family from generation to generation basis for the treatment of heart and lung diseases, has cured routine heart and lung diseases up to ten thousand when inventor obtains prescription.For proving advantage of the present invention, below according to clinical observation on the therapeutic effect, further set forth application of the present invention and beneficial effect.
Clinical verification: following all cases are applicant's clinic case, and be all through County Hospital, make a definite diagnosis case.
One. physical data and diagnostic criteria and Therapeutic Method
1. diabetics 51 examples, 35～78 years old age, make a definite diagnosis 10 days～37 years, 32 of male, 19 of women, wherein, heart patient 11 examples that occur together, suffer from asthma person's 3 examples, concurrent vasculitis person's 9 examples.
Diagnostic criteria: with reference to People's Health Publisher Weng Weiliang chief editor " Chinese medicine clinical pharmacology ".Patient has polyuria, polydipsia, polyphagia, fatigue, " three-many-one-little " symptom of becoming thin.Random blood sugar value is higher than 11.1mmol/L.Fasting glucose is higher than 7.0mmol/L.Complication is with reference to dependent diagnostic standard.
Therapeutic Method: get embodiment medicated powder 15g, 30g, mix well clearly in right amount with raw egg, coated appointment acupuncture point and arch of the foot, removed after 12 hours respectively.With other diseases person, with reference to following related methods for the treatment of, treat simultaneously.
2. bronchitis, asthma, emphysema, pulmonary heart disease, bronchiectasis patient is totally 108 examples:
Diagnostic criteria: meet Chinese Medicine science and technology publishing house's " rural area prevention and control of frequently occurring " bronchitis in 1993, asthma, emphysema, pulmonary heart disease, the clinical manifestation under bronchiectasis item and diagnostic criteria.
Therapeutic Method: get embodiment medicated powder 25g, 10g, 10g, to remove the peel raw egg or live chickens bile is mixed well in right amount, coated arch of the foot and shirtfront, back are specified acupuncture point, remove after 15 hours.
3. cardiac's totally 127 examples, maximum 81 years old age, minimal ages 27 years old.
Diagnostic criteria: make a definite diagnosis with reference to clinical manifestation and diagnostic criteria under Chinese Medicine science and technology publishing house's " rural area prevention and control of frequently occurring " continuous item in 1993.
Therapeutic Method: get embodiment medicated powder 10g, 5g, 20g, mix well clearly in right amount with raw egg, coated shirtfront, back are specified acupuncture point and arch of the foot, remove after 15 hours.
4. vasculitis, the routine patient of phlebitis 21; Head Necrosis of 8 Cases.
Therapeutic Method: vasculitis is got embodiment medicated powder and mixed well in right amount with live chickens bile in right amount; Phlebitis is got embodiment medicated powder in right amount with the appropriate furnishing pasty state of vinegar; Femur head necrosis is got embodiment medicated powder and with ethanol or Chinese liquor appropriate (allergy sufferers water tune), is mixed well in right amount, and coated affected part and arch of the foot, removed after 8～12 hours.
The above disease can be applied ointment or plaster without interval continuously at acute attack stage.Generally stick and can cure 1～4 course for the treatment of, do not recur after more.
Two. criterion of therapeutical effect and therapeutic outcome
Following criterion of therapeutical effect is all formulated with practical situation with reference to People's Health Publisher Weng Weiliang chief editor " Chinese medicine clinical pharmacology ".
1. diabetes:
Recovery from illness: clinical symptoms, sign disappear, and fasting glucose and post-prandial glycemia drop to normal range, follows up a case by regular visits to not recurrence above in 1 year.
Effective: clinical symptoms, sign disappear, fasting glucose and after the meal 2 hours blood glucoses decline and approach normal value but do not reach normal value, the person that do not re-use medicine.
Effective: clinical symptoms, sign are improved, fasting glucose and after the meal 2 hours blood glucoses decline, also even with the suitable effector of medicine.
Invalid: clinical symptoms, sign are without improving or worsening.
Cure 41 examples, effective: 6 examples, effective 3 examples, invalid 1 example.
2. bronchitis, asthma, emphysema, pulmonary heart disease, bronchiectasis: cure: clinical symptoms, sign disappear, follows up a case by regular visits to recurrence above in 1 year after healing.Effective: clinical symptoms, sign are improved, the person that still occasionally uses medicine.Invalid: clinical symptoms, sign are without improving or worsening.Cure 97 examples, effective 10 examples, invalid 1 example.
3. heart disease: cure: clinical symptoms, sign disappear, follows up a case by regular visits to recurrence above in 1 year after healing.Effective: clinical symptoms, sign are improved, the person that still occasionally uses medicine.Invalid: clinical symptoms, sign are without improving or worsening.Cure 112 examples, effective 13 examples, invalid 2 examples.
4. vasculitis, phlebitis, femur head necrosis: cure: clinical symptoms, sign disappear, follow up a case by regular visits to recurrence above in 1 year after healing.Effective: clinical symptoms, sign are improved, and still occasionally with medicine, control.Invalid: clinical symptoms, sign are without improving or worsening.
Vasculitis, phlebitis, cure 16 examples, effective 4 examples, invalid 1 example.Femur head necrosis, cures 6 examples, effective 1 example,
Invalid 1 example.
Model case:
1. Feng, man, 63 years old, tachycardia 7 years, heavy when light during the state of an illness, and progressively develop into coronary heart disease companion angina pectoris more than 2 years, and by morbidity in 2,3 months, develop into for 1 time and monthly fall ill 1 to 4 time, stick one pair of recovery from illness of the present invention, within 17 years, do not have an attack of one's old illness so far.
2. Zhang, man, 71 years old, 21 years companion's heart disease of asthma 5 years, all fall ill every year, the transfusion control state of an illness after morbidity.This time asthma attack, increases the weight of heart sympton, and control of medication heterodyne applies 4 pairs of recoveries from illness of the present invention, and autumn coming year is because of tired and be affected by the cold and again bring out, but symptom is light than before, sticks again 2 pairs of recoveries from illness of the present invention, and 7 years so far healthy.
3. Liu, female, 68 years old, 39 years companion's chronic tracheitiss of heart disease 36 years, diabetes 2 years, because cold cough brings out pulmonary heart disease, fasting glucose 13.2mmol/L, applies 14 pairs of the present invention and also coordinates oral medicine, looks into fasting glucose 6.3mol/L, and recovery from illness, did not recur for 4 years so far.
4. Hu, man, 57 years old, diabetes 11 years, heart disease 6 years, vasculitis half a year, fasting glucose 12.5mmol/L, applies 15 pairs of the present invention, looks into fasting glucose 6.2mmol/L, and all disease knowing are removed, and within 2 years so far, do not recur recovery from illness.
5. bavin, man, 55 years old, because of one month body weight thin 40 jin without reason, remove examination in hospital then, look into fasting glucose 19.58mmol/L, be diagnosed as diabetes, xerostomia, easily hungry, polyuria, sticks the fasting glucose 11.8mmol/L that tests oneself after 1 pair of the present invention, and 2 Fu Houqu hospitals look into fasting glucose 14.0mmol/L, the easy hungry transference cure of xerostomia, body weight increases 2kg, stick 8 pairs after self detecting blood sugar 10.2mmol/L, existing still in treatment.(inspection report see reference data)
Claims (3)
1. treatment heart disease, vasculitic medicine for external use, is characterized in that by Semen Momordicae, Semen Pharbitidis, Fructus Piperis, as effective ingredient, its weight portion is 1.5～15 parts of Semen Momordicaes, 1～15 part of Semen Pharbitidis, 1～6 part, Fructus Piperis.
2. medicine for external use according to claim 1, is characterized in that also adding Semen Armeniacae Amarum as effective ingredient, and its weight portion is 1.5～15 parts of Semen Momordicaes, 1～15 part of Semen Pharbitidis, 1～6 part, Fructus Piperis, 1～9 part, Semen Armeniacae Amarum.
3. according to the medicine for external use described in the arbitrary claim of claim 1 or 2, in preparation, treat chronic cardiac insufficiency, arrhythmia, coronary heart diseases and angina pectoris, myocardial infarction, rheumatic heart disease, pulmonary heart disease, diabetes, vasculitis, phlebitis, application in femur head necrosis medicine, and there is the application in diabetes medicament in preparation treatment asthma, emphysema, bronchitis, bronchiectasis and the prevention of reduction blood glucose value.
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| CN201310464145.2A CN103520288A (en) | 2011-07-28 | 2011-07-28 | External drug for treating heart disease and vasculitis, and its application |
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| CN201310464145.2A CN103520288A (en) | 2011-07-28 | 2011-07-28 | External drug for treating heart disease and vasculitis, and its application |
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| CN2011102132340A Division CN102266394A (en) | 2011-07-28 | 2011-07-28 | Topical medicinal preparation for treating heart and lung diseases, diabetes and angiitis and application thereof |
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| CN106420897A (en) * | 2016-10-10 | 2017-02-22 | 毛里夏里甫·哈帕 | Fuming preparation for treating high blood pressure and rheumatic heart disease, preparing method and application method |
| CN113143986A (en) * | 2021-05-06 | 2021-07-23 | 广东医科大学 | Medicine for treating pulmonary tuberculosis |
| CN115068531A (en) * | 2022-06-22 | 2022-09-20 | 四川东方猫建筑设计有限公司 | External application medicine for treating cardiopulmonary diseases |
| CN115671201A (en) * | 2021-07-28 | 2023-02-03 | 上海中医药大学附属龙华医院 | Traditional Chinese medicine plaster for treating premature beat |
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| CN1277864A (en) * | 1999-06-22 | 2000-12-27 | 史东永 | External application medicine for treating hypertension |
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| CN106420897A (en) * | 2016-10-10 | 2017-02-22 | 毛里夏里甫·哈帕 | Fuming preparation for treating high blood pressure and rheumatic heart disease, preparing method and application method |
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| CN115671201A (en) * | 2021-07-28 | 2023-02-03 | 上海中医药大学附属龙华医院 | Traditional Chinese medicine plaster for treating premature beat |
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| CN115068531A (en) * | 2022-06-22 | 2022-09-20 | 四川东方猫建筑设计有限公司 | External application medicine for treating cardiopulmonary diseases |
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Application publication date: 20140122 |