CN103519180B - Preparation method of maca extract - Google Patents
Preparation method of maca extract Download PDFInfo
- Publication number
- CN103519180B CN103519180B CN201310523259.XA CN201310523259A CN103519180B CN 103519180 B CN103519180 B CN 103519180B CN 201310523259 A CN201310523259 A CN 201310523259A CN 103519180 B CN103519180 B CN 103519180B
- Authority
- CN
- China
- Prior art keywords
- extract
- agate coffee
- tank
- ceramic membrane
- extraction time
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 240000000759 Lepidium meyenii Species 0.000 title claims abstract description 19
- 235000000421 Lepidium meyenii Nutrition 0.000 title claims abstract description 19
- 235000012902 lepidium meyenii Nutrition 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- 239000000919 ceramic Substances 0.000 claims abstract description 20
- 239000007788 liquid Substances 0.000 claims abstract description 8
- 238000000605 extraction Methods 0.000 claims description 36
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 34
- 239000012528 membrane Substances 0.000 claims description 23
- 239000000463 material Substances 0.000 claims description 19
- 239000012141 concentrate Substances 0.000 claims description 15
- 239000000706 filtrate Substances 0.000 claims description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 239000012530 fluid Substances 0.000 claims description 10
- 238000001471 micro-filtration Methods 0.000 claims description 10
- 238000005507 spraying Methods 0.000 claims description 10
- 239000006228 supernatant Substances 0.000 claims description 10
- 230000015572 biosynthetic process Effects 0.000 claims description 5
- 230000009977 dual effect Effects 0.000 claims description 5
- 239000013049 sediment Substances 0.000 claims description 5
- 230000008719 thickening Effects 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 238000000034 method Methods 0.000 abstract description 8
- 125000004383 glucosinolate group Chemical group 0.000 abstract description 7
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000011031 large-scale manufacturing process Methods 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract description 2
- 238000005374 membrane filtration Methods 0.000 abstract 2
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 description 6
- 239000004480 active ingredient Substances 0.000 description 5
- 238000000926 separation method Methods 0.000 description 5
- 238000001514 detection method Methods 0.000 description 3
- 230000035558 fertility Effects 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 2
- 230000002929 anti-fatigue Effects 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- -1 benzyl mustard oil glycosides Chemical class 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 241000208340 Araliaceae Species 0.000 description 1
- 241000219193 Brassicaceae Species 0.000 description 1
- 208000020401 Depressive disease Diseases 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 235000004458 antinutrient Nutrition 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000008164 mustard oil Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
- Tea And Coffee (AREA)
Abstract
The invention discloses a preparation method of a maca extract. The method comprises the steps of: (1) maca extract liquid preparation; (2) maca extract liquid pretreatment; (3) ceramic membrane filtration; (4) vacuum concentration; and (5) spray drying. The content of an effective component glucosinolate in the extract provided by the invention can be improved by more than 3 times that of existing methods. Also, with the ceramic membrane filtration step, the physical and chemical characteristics of the maca effective component can be well preserved. With the method, product quality can be improved, production cost can be reduced, and environment can be protected. The method is beneficial for large-scale productions.
Description
Technical field
The present invention relates to the extraction separation and purification of effective ingredients in plant, particularly a kind of preparation method of Maca extract.
Background technology
Agate coffee (Maca), have another name called Peruvian ginseng, maino, ayak chichira, ayakwillku etc., originate in the mountain area, Andean, South America of height above sea level 3500-4500 meters, main producing region is in the Hu Ning (Junin) of Peru and Pasco (Pasco) area, for Cruciferae separate row Vegetable spp plant, be often called as Peru's ginseng.Agate coffee has had more than 5800 year in the edible history in South America, traditionally as food and herbal medicine, can improvement function, and improve fertility, antifatigue, antitumor and be used for the treatment of depression, asthma and female dimacteric syndrome etc.
Protein, amino acid, carbohydrate, mineral matter and multivitamin is rich in agate coffee, recent years, efficacy study showed, agate coffee in raising fertility, antifatigue, improve in osteoporosis etc. there is remarkable efficacy, and also have effect in improvement function and memory etc.Most researcher thinks that macamide, benzyl mustard oil glycosides and catabolite isothiocyanic acid benzyl fat thereof are its main active and property material.Glucosinolate and volatile decomposition products isothiocyanic acid lipid material thereof by traditional anti-nutrient substance change into antitumor, improve the active material in fertility etc. with great potential.
The separation of current agate coffee extract is main mainly with conventional separation methods, as plate-frame filtering method, plate-frame filtering needs intermittently operated, labour intensity is large, production efficiency is low, not high to the clearance of tannin, starch, resin and protein, and the dissolubility of products obtained therefrom is not good, thus solid yields is very high, produces considerable influence to the stability of the application of extract later stage and product.
Summary of the invention
Object of the present invention is just to provide a kind of preparation method of Maca extract; Agate coffee thing active ingredient glucosinolate content >=10% that the method obtains, clear after dissolving, impurity content is low, is suitable for preparing food and health products.
The preparation method of a kind of Maca extract of the present invention, comprises the steps:
(1) the preparation of agate coffee extract
Agate coffee medicinal material is on average added in three extractors A, B, C of group tank counter-flow extraction, add the ethanol of medicinal material weight 6-10 times, volume fraction 60-90%, extract at 60-80 DEG C, at gradient formation stages, A tank extraction time is respectively 5min, 15min, and B tank extraction time is 10min; In the extraction stage, each tank extraction time is 2h; In extraction ending phase, extraction time is 2h; Merge each tank extract, obtain agate coffee extract;
(2) the pretreatment of agate coffee extract
Owing to containing more solid particle polluter in agate coffee extract, directly can cause the severe contamination of film with ceramic membrane, reduce the service life of film, thus the pretreatment of liquid is the key ensureing film serviceability, and can extend the service life of film.Adopt Alfa Laval disc centrifuge centrifugal under 6000r/min agate coffee extract, collect supernatant, discard sediment;
(3) ceramic membrane filter
By step (2) gained supernatant adopt membrane aperture to be that the ceramic membrane unit of 0.05 μm-0.2 μm carries out micro-filtration separating treatment, wherein the combination of unit is two strings four and formulas, fills 61,0.05 μm of-0.2 μm of film core, totally 488 in every root film pipe; Operating temperature: 25-30 DEG C, operating pressure: 0.2 MPa, obtains filtrate; After micro-filtration, wash 3 times with water to trapped fluid top, temperature is washed on top: 30-40 DEG C, and pressure is washed on top: 0.2-0.5MPa, obtains ceramic membrane filter liquid; Require filtrate turbidity≤3.0NTU;
(4) Vacuum Concentration
Adopt the filtered fluid of dual-effect concentrator to step (3) gained to concentrate, thickening temperature 70 DEG C, filtrate is concentrated in every 1ml concentrate containing 500mg medicinal material;
(5) spraying dry
Concentrate is carried out spraying dry, controls leaving air temp 70-80 DEG C, the dry thing of gained is Maca extract.
The inventive method compared with prior art, has following characteristics:
(1) adopt in ceramic membrane separation process without phase transformation, be conducive to the physicochemical property preserving effective component in Maka, as often as possible retain the plurality of active ingredients of agate coffee medicinal material, particularly can retain some heat-sensitive ingredients in agate coffee extract, as alkaloid, glucosinolate etc.
(2) improve the quality of product, the existence of the non-effective component of high molecular weight or low effective component, the concentration of effective ingredient in Chinese is reduced, and drug effect weakens, and reduces stability and the sense index of extract.And utilize Ceramic Membranes Separating Technique can remove the non-effective component of high molecular weight or low effective component to greatest extent, thus this technology can make product quality obtain larger raising.
(3) owing to not consuming organic solvent, and do not add other any material in separation process, therefore compared with conventional method, can operation be reduced, shorten the production cycle, reduce production cost, reduce environmental pollution, and whole operation can be carried out continuously, is beneficial to large-scale production.
(4) can improve Maca extract stability, the turbidity of Maca extract solution can be reduced.
Detailed description of the invention
Embodiment 1
(1) the preparation of agate coffee extract
Agate coffee medicinal material is on average added in three extractors A, B, C of group tank counter-flow extraction, add the ethanol of medicinal material weight 8 times, volume fraction 70%, extract at 60 DEG C, at gradient formation stages, A tank extraction time is respectively 5min, 15min, and B tank extraction time is 10min; In the extraction stage, each tank extraction time is 2h; In extraction ending phase, extraction time is 2h; Merge each tank extract, obtain agate coffee extract;
(2) the pretreatment of agate coffee extract
Adopt Alfa Laval disc centrifuge centrifugal under 6000r/min agate coffee extract, collect supernatant, discard sediment;
(3) ceramic membrane filter
By step (2) gained supernatant adopt membrane aperture to be that the ceramic membrane unit of 0.05 μm carries out micro-filtration separating treatment, wherein the combination of unit is two strings four and formulas, fills 61,0.05 μm of film core, totally 488 in every root film pipe; Operating temperature: 25 DEG C, operating pressure: 0.2 MPa, obtains filtrate; After micro-filtration, wash 3 times with water to trapped fluid top, temperature is washed on top: 30 DEG C, and pressure is washed on top: 0.2MPa, obtains ceramic membrane filter liquid; Detection filtrate turbidity is 2.3NTU;
(4) Vacuum Concentration
Adopt the filtered fluid of dual-effect concentrator to step (3) gained to concentrate, thickening temperature 70 DEG C, is concentrated into filtrate in every 1ml concentrate and contains
500mg medicinal material;
(5) spraying dry
Concentrate is carried out spraying dry, controls leaving air temp 80 DEG C, the dry thing of gained is Maca extract.Wherein the content of active ingredient glucosinolate is 11.2%.
Embodiment 2
(1) the preparation of agate coffee extract
Agate coffee medicinal material is on average added in three extractors A, B, C of group tank counter-flow extraction, add medicinal material weight 9 times, the ethanol of volume fraction 90%, extract at 70 DEG C, at gradient formation stages, A tank extraction time is respectively 5min, 15min, and B tank extraction time is 10min; In the extraction stage, each tank extraction time is 2h; In extraction ending phase, extraction time is 2h; Merge each tank extract, obtain agate coffee extract;
(2) the pretreatment of agate coffee extract
Adopt Alfa Laval disc centrifuge centrifugal under 6000r/min agate coffee extract, collect supernatant, discard sediment;
(3) ceramic membrane filter
By step (2) gained supernatant adopt membrane aperture to be that the ceramic membrane unit of 0.09 μm carries out micro-filtration separating treatment, wherein the combination of unit is two strings four and formulas, fills 61,0.09 μm of film core, totally 488 in every root film pipe; Operating temperature: 30 DEG C, operating pressure: 0.2 MPa, obtains filtrate; After micro-filtration, wash 3 times with water to trapped fluid top, temperature is washed on top: 30 DEG C, and pressure is washed on top: 0.2MPa, obtains ceramic membrane filter liquid; Detection filtrate turbidity is 1.9NTU;
(4) Vacuum Concentration
Adopt the filtered fluid of dual-effect concentrator to step (3) gained to concentrate, thickening temperature 70 DEG C, is concentrated into filtrate in every 1ml concentrate and contains
500mg medicinal material;
(5) spraying dry
Concentrate is carried out spraying dry, controls air-out humidity 70 DEG C, the dry thing of gained is Maca extract.Wherein the content of active ingredient glucosinolate is 11.7%.
Embodiment 3
(1) the preparation of agate coffee extract
Agate coffee medicinal material is on average added in three extractors A, B, C of group tank counter-flow extraction, add medicinal material weight 7 times, the ethanol of volume fraction 80%, extract at 80 DEG C, at gradient formation stages, A tank extraction time is respectively 5min, 15min, and B tank extraction time is 10min; In the extraction stage, each tank extraction time is 2h; In extraction ending phase, extraction time is 2h; Merge each tank extract, obtain agate coffee extract;
(2) the pretreatment of agate coffee extract
Adopt Alfa Laval disc centrifuge centrifugal under 6000r/min agate coffee extract, collect supernatant, discard sediment;
(3) ceramic membrane filter
By step (2) gained supernatant adopt membrane aperture to be that the ceramic membrane unit of 0.2 μm carries out micro-filtration separating treatment, wherein the combination of unit is two strings four and formulas, fills 61,0.2 μm of film core, totally 488 in every root film pipe; Operating temperature: 30 DEG C, operating pressure: 0.2 MPa, obtains filtrate; After micro-filtration, wash 3 times with water to trapped fluid top, temperature is washed on top: 30 DEG C, and pressure is washed on top: 0.2MPa, obtains ceramic membrane filter liquid; Detection filtrate turbidity is 2.2NTU;
(4) Vacuum Concentration
Adopt the filtered fluid of dual-effect concentrator to step (3) gained to concentrate, thickening temperature 70 DEG C, is concentrated into filtrate in every 1ml concentrate and contains
500mg medicinal material;
(5) spraying dry
Concentrate is carried out spraying dry, controls air-out humidity 75 DEG C, the dry thing of gained is Maca extract.Wherein the content of active ingredient glucosinolate is 11.7.
Claims (1)
1. the preparation method of Maca extract, is characterized in that comprising the steps:
(1) the preparation of agate coffee extract
Agate coffee medicinal material is on average added in three extractors A, B, C of group tank counter-flow extraction, add the ethanol of medicinal material weight 6-10 times, volume fraction 60-90%, extract at 60-80 DEG C, at gradient formation stages, A tank extraction time is respectively 5min, 15min, and B tank extraction time is 10min; In the extraction stage, each tank extraction time is 2h; In extraction ending phase, extraction time is 2h; Merge each tank extract, obtain agate coffee extract;
(2) the pretreatment of agate coffee extract
Adopt Alfa Laval disc centrifuge centrifugal under 6000r/min agate coffee extract, collect supernatant, discard sediment;
(3) ceramic membrane filter
By step (2) gained supernatant adopt membrane aperture to be that the ceramic membrane unit of 0.05 μm-0.2 μm carries out micro-filtration separating treatment, wherein the combination of unit is two strings four and formulas, fills 61,0.05 μm of-0.2 μm of film core, totally 488 in every root film pipe; Operating temperature: 25-30 DEG C, operating pressure: 0.2 MPa, obtains filtrate; After micro-filtration, wash 3 times with water to trapped fluid top, temperature is washed on top: 30-40 DEG C, and pressure is washed on top: 0.2-0.5MPa, obtains ceramic membrane filter liquid; Require filtrate turbidity≤3.0NTU;
(4) Vacuum Concentration
Adopt the filtered fluid of dual-effect concentrator to step (3) gained to concentrate, thickening temperature 70 DEG C, filtrate is concentrated in every 1ml concentrate containing 500mg medicinal material;
(5) spraying dry
Concentrate is carried out spraying dry, controls leaving air temp 70-80 DEG C, the dry thing of gained is Maca extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310523259.XA CN103519180B (en) | 2013-10-30 | 2013-10-30 | Preparation method of maca extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310523259.XA CN103519180B (en) | 2013-10-30 | 2013-10-30 | Preparation method of maca extract |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103519180A CN103519180A (en) | 2014-01-22 |
| CN103519180B true CN103519180B (en) | 2015-03-18 |
Family
ID=49921816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310523259.XA Active CN103519180B (en) | 2013-10-30 | 2013-10-30 | Preparation method of maca extract |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103519180B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103766907A (en) * | 2014-02-20 | 2014-05-07 | 云南众爱生物科技有限公司 | Pure maca tablets and preparation method thereof |
| CN104256608B (en) * | 2014-10-11 | 2016-05-11 | 王衍彬 | A kind of agate coffee extract health product and application thereof |
| CN105030872A (en) * | 2015-07-30 | 2015-11-11 | 太阳树（厦门）生物工程有限公司 | Extraction process for Maca extractive |
| CN105558243A (en) * | 2016-01-04 | 2016-05-11 | 青海汇珍生物科技有限公司 | Maca extract, maca candy sheet and preparation method thereof |
| CN105994861A (en) * | 2016-05-30 | 2016-10-12 | 云南力奥天然饮品有限公司 | Preparation technology of Maca coffee beverage |
| CN106434227A (en) * | 2016-12-08 | 2017-02-22 | 枫林健康酒业有限公司 | Anti-fatigue Maca wine and preparation method thereof |
| CN108272848A (en) * | 2018-04-18 | 2018-07-13 | 佛山市飞程信息技术有限公司 | A kind of extraction process of Maca extract |
| CN113575949B (en) * | 2021-08-04 | 2024-01-05 | 湖南华诚生物资源股份有限公司 | Maca concentrated juice and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1800122A (en) * | 2005-12-09 | 2006-07-12 | 浙江大学 | Giant knotweed rhizome active ingredient emodin extraction method |
| CN101138418A (en) * | 2007-10-16 | 2008-03-12 | 浙江大学 | Hop supercritical residues comprehensive utilization method |
| CN102579547A (en) * | 2012-03-26 | 2012-07-18 | 张丽琴 | Method for extracting active ingredients of maca |
| CN102988432A (en) * | 2012-12-11 | 2013-03-27 | 广东新峰药业股份有限公司 | Preparation method of traditional Chinese medicine aqueous solution for antibiosis, antiphlogosis and antitumor |
| CN103040896A (en) * | 2013-01-06 | 2013-04-17 | 云南圣草峰生物科技有限公司 | Preparation method of maca extractive |
-
2013
- 2013-10-30 CN CN201310523259.XA patent/CN103519180B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1800122A (en) * | 2005-12-09 | 2006-07-12 | 浙江大学 | Giant knotweed rhizome active ingredient emodin extraction method |
| CN101138418A (en) * | 2007-10-16 | 2008-03-12 | 浙江大学 | Hop supercritical residues comprehensive utilization method |
| CN102579547A (en) * | 2012-03-26 | 2012-07-18 | 张丽琴 | Method for extracting active ingredients of maca |
| CN102988432A (en) * | 2012-12-11 | 2013-03-27 | 广东新峰药业股份有限公司 | Preparation method of traditional Chinese medicine aqueous solution for antibiosis, antiphlogosis and antitumor |
| CN103040896A (en) * | 2013-01-06 | 2013-04-17 | 云南圣草峰生物科技有限公司 | Preparation method of maca extractive |
Non-Patent Citations (5)
| Title |
|---|
| 动态罐组式逆流提取技术在中药生产中的应用研究进展;谢志鹏等;《中国中药杂志》;20070515;第32卷(第10期);第884-887页 * |
| 玛咖的营养成分及功效研究进展;尹子娟等;《云南农业科技》;20120925(第5期);61-64页 * |
| 罐组式动态逆流提取技术及其在中药提取中的应用;季艳艳等;《中国现代中药》;20061216;第8卷(第12期);第27-30页 * |
| 罐组逆流提取工艺参数的多指标优化方法研究;陈勇等;《中国药学杂志》;20060708;第41卷(第13期);第998-1001页 * |
| 陶瓷膜强化过滤技术的应用;丁志斌等;《净水技术》;20121225;第31卷(第6期);14-17页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103519180A (en) | 2014-01-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103519180B (en) | Preparation method of maca extract | |
| CN102993328B (en) | Method for comprehensively extracting polysaccharides, polyphenol and saponin from camellia oleifera abel defatted cakes | |
| CN103012095B (en) | Method for combined extraction of variety of functional components of ginger | |
| CN105106351A (en) | Production method of aronia melanocarpa extract | |
| CN106381319A (en) | High-efficiency extraction and separation method of grape seed proanthocyanidin oligomer | |
| CN104961839B (en) | The preparation method of one species specificity pachymaran granule | |
| CN104059163B (en) | Qaidam, Qinghai lycium barbarum polysaccharide is extracted and is separated novel preparation method | |
| CN104523836A (en) | Method for comprehensively extracting protein, polysaccharide and polyphenol from avocado kernels | |
| CN103819577A (en) | Method for preparing spirulina platensis polysaccharide | |
| CN102660137B (en) | Method for efficiently preparing natural red date pigment | |
| CN100439319C (en) | Method for preparing salviol acid A | |
| CN104045724A (en) | Method for extracting and preparing polysaccharide from inonotus obliquus | |
| CN103054021A (en) | Method for extracting compound from nitraria tangutorum peel | |
| CN104045727B (en) | Utilize the method for AB-8 low pole resin for the thick polysaccharide of Inonotus obliquus | |
| CN102453601A (en) | Extraction method of Cinnamomum camphora seed oil by ultrasound-assisted compound enzyme | |
| CN101817809A (en) | Method for producing flavonoids by using pectin-extracted orange peel | |
| CN106491458A (en) | A kind of preparation method and applications of tea polyphenols condensed cream | |
| CN101775233A (en) | Membrane separation integrated technology-based preparation method for producing deodorized red radish pigment | |
| CN106008211A (en) | Method for extraction of cynarin from cynara scolymus by membrane integration technology | |
| CN104045728B (en) | Adopt the method for D101 resin for the thick polysaccharide of Inonotus obliquus | |
| CN104857035A (en) | Ginkgo biloba leaf extract preparation method | |
| CN104045726B (en) | Utilize the method for the refining thick polysaccharide of Inonotus obliquus of macroporous absorbent resin DA201 | |
| CN107473979A (en) | A kind of processing method of film extraction theanine | |
| CN103725740A (en) | Method for extracting glycoprotein by using scollop blanching liquid | |
| CN110054706A (en) | The method for the fucoidin concentration extracted in one main laminaria |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |