CN103505386B - Fresh eclipta composition - Google Patents

Fresh eclipta composition Download PDF

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CN103505386B
CN103505386B CN201210215999.2A CN201210215999A CN103505386B CN 103505386 B CN103505386 B CN 103505386B CN 201210215999 A CN201210215999 A CN 201210215999A CN 103505386 B CN103505386 B CN 103505386B
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eclipta
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刘子平
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Abstract

The invention provides compositions and the production technology thereof of a kind of fresh Herba Ecliptae, the compositions of described fresh Herba Ecliptae comprises: fresh Herba Ecliptae extracting solution (A), fresh Herba Portulacae extracting solution (B), fresh Folium Camelliae sinensis extracting solution (C), fresh Herba Spinaciae extracting solution (E), Radix Rehmanniae extracting solution (D).

Description

Fresh eclipta composition
Technical field
The present invention relates to the production technology of a kind of fresh eclipta composition and this fresh eclipta composition, particularly a kind of containing any photosensitive and chemical irritants, there is the fresh eclipta composition and its production technology that promote human body melanin granule naturally to synthesize and realize the natural blackening of poliosis.
Background technology
Human body melanin granule produces synthesis by melanocyte, participates in body metabolism and plays an important role in metabolism, can form skin pigment, and protection skin, from ultraviolet radiation, fills in medula pipe, can form the black of hair.The phenylalanine of another synthesis of melanin is relevant with the memory function of neurotransmitter and brain cell with tyrosine:
When lacking melanin granule in human body, following serious disease can be produced:
1, cranial nerve cell lacks melanin granule---and lessen one's memory, lose, cause alzheimer disease;
2, skin lacks melanin granule---vitiligo, albinism, dermatitis solaris;
3, hair lacks melanin granule---poliosis;
4, neurotransmitter dopamine reduces---Parkinson's disease.
Above-mentioned disease up to now, all without effective Drug therapy.One of major reason is that melanin granule automatically cannot synthesize in human body.Hair color series products commercially available is at present still based on hair dyeing product, but the chemical substance such as m-diaminobenzene. in hair dye may cause allergy, the side effect such as carcinogenic.Chinese medicine hair color product is additive mainly with Chinese medicine extract such as the kidney invigorating such as Semen Sesami Nigrum, the Radix Polygoni Multiflori, and because pharmacy and extraction process are still based on conventional boil technique, cause effective active matter inactivation, hair color effect is very undesirable.
At present, according to the medicine principle of generally acknowledging, the synthesis of melanin granule has to pass through 5 biochemical reactions processes and can finally synthesize, and obstacle appears in any one link, all can not synthesizing black crude granule, wherein the content of tyrosine and the activity of tryrosinase are the keys of synthesis.And as follows about the related link research of technique:
Within (1) 1997 year, American scientist Prusiner is because finding that Protein virus invades central nervous system, the content of DOPA (Dopa) in cerebral hippocampus entorhinal area cutaneous nerve cell (memory cell) is caused to decline, melanin granule disappears, Vacuole formation, indicate the death of cranial nerve cell, cause hypomnesis, forfeiture, form alzheimer disease, this technology is awarded Nobel physiology and Medicine.
Within (2) 2000 years, Sweden scientist Gosta Carlsson, American scientist Greengard, Kan Deeryin find that between neurocyte in information exchanging process, lacking of neurotransmitter dopamine causes the reason of Parkinson's disease and obtain Nobel physiology and Medicine.
Just because of melanin granule building-up process, extremely complexity, reacting substance and reaction condition require very strict, up to now, be external or domestic scientific and technological circle, the medical circle report that all do not have definite theory and clear and definite scientific research data and tables of data person of good sense body melanin granule to be synthesized.
Summary of the invention
Therefore, the present invention is in view of promoting also defectiveness and the invention completed of product that human body melanin granule synthesizes naturally in prior art.
The object of the present invention is to provide a kind of containing any photosensitive and chemical irritants and the production technology of the fresh eclipta composition that human body melanin granule can be promoted naturally to synthesize and this fresh eclipta composition.
The present inventors find to select diverse pure fresh plant and Chinese medicine species with Chinese medicine, specifically, fresh Herba Ecliptae extracting solution (A), fresh Herba Portulacae extracting solution (B), fresh Folium Camelliae sinensis extracting solution (C), fresh Herba Spinaciae extracting solution (E), Radix Rehmanniae extracting solution (D) are mixed, with the extraction process of original creation, the biological activity of the important substance such as enzyme, kinases, phenylalanine, tyrosine, biological Saponin, ATP can be preserved to greatest extent, thus complete the present invention.
The invention provides a kind of fresh eclipta composition, it is characterized in that, containing fresh Herba Ecliptae extracting solution (A), fresh Herba Portulacae extracting solution (B), fresh Folium Camelliae sinensis extracting solution (C), fresh Herba Spinaciae extracting solution (E), Radix Rehmanniae extracting solution (D).
Wherein, described fresh Herba Ecliptae extracting solution (A) content is 20 ~ 70%, the content of described fresh Herba Portulacae extracting solution (B) is 10 ~ 30%, the content of described fresh Folium Camelliae sinensis extracting solution (C) is 7 ~ 10%, the content of described fresh Herba Spinaciae extracting solution (E) is 3 ~ 10%, and the content of described Radix Rehmanniae extracting solution (D) is 10 ~ 30%.
Described fresh Herba Ecliptae extracting solution (A) content is preferably 60%, the content of described fresh Herba Portulacae extracting solution (B) is preferably 15%, the content of described fresh Folium Camelliae sinensis extracting solution (C) is preferably 5%, the content of described fresh Herba Spinaciae extracting solution (E) is preferably 5%, and the content of described Radix Rehmanniae extracting solution (D) is preferably 10%.
In addition, in described fresh eclipta composition fresh Herba Ecliptae extracting solution (A) by fresh Herba Ecliptae, Herba Ecliptae dry product, Radix Ginseng, Radix Polygoni Multiflori, Semen Sesami Nigrum and 25% rare alcohol make.
Wherein, the content of described fresh Herba Ecliptae is 10 ~ 55%, and the content of described Herba Ecliptae dry product is 10 ~ 15%, the content of described Radix Ginseng is 5 ~ 10%, the content of described Radix Polygoni Multiflori is 5 ~ 10%, and the content of described Semen Sesami Nigrum is 5 ~ 10%, and the content of rare alcohol of described 25% is 20 ~ 45%.
Further, the content of described fresh Herba Ecliptae is preferably 30%, and described Herba Ecliptae dry product is preferably 8%, the content of described Radix Ginseng is preferably 8%, the content of described Radix Polygoni Multiflori is preferably 7%, and the content of described Semen Sesami Nigrum is preferably 7%, and the content of rare alcohol of described 25% is preferably 40%.
In addition, the fresh Herba Portulacae extracting solution in described fresh eclipta composition is made up of fresh Herba Portulacae and 15% rare alcohol.
Wherein, the content of described fresh Herba Portulacae is 10 ~ 80%, and the content being preferably 30%, 15% rare alcohol is 20 ~ 90%, is preferably 70%.
In addition, the fresh Folium Camelliae sinensis extracting solution (C) in described fresh eclipta composition is made up of fresh Folium Camelliae sinensis and deionized water.
Wherein, the content of described fresh Folium Camelliae sinensis is 10 ~ 80%, and be preferably 30%, the content of deionized water is 20 ~ 90%, is preferably 70%.
In addition, the Radix Rehmanniae extracting solution in described fresh eclipta composition is made up of the medical alcohol of Radix Rehmanniae and 25 ~ 50% concentration, and the content of described Radix Rehmanniae is 10 ~ 80%, and be preferably 30%, the content of the medical alcohol of described 25-50% concentration is 20 ~ 90%, is preferably 70%.
In addition, the fresh Herba Spinaciae extracting solution in fresh eclipta composition is made up of Herba Spinaciae and deionized water, and the content of described Herba Spinaciae is 30 ~ 70%, and be preferably 50%, the content of described deionized water is 30 ~ 70%, is preferably 50%.
In addition, the present invention also provides a kind of production technology manufacturing fresh eclipta composition, it is characterized in that, comprise: by fresh Herba Portulacae extracting solution, fresh Folium Camelliae sinensis extracting solution, fresh Herba Ecliptae extracting solution, Radix Rehmanniae extracting solution, the mixing of fresh Herba Spinaciae extracting solution, temperature 22 ~ 24 DEG C, leave standstill 8 days, filter with 300 object gauzes, it is carried out disinfection, slightly put forward the operation of mixed liquor; With slightly carrying in mixed liquor 95% ethanol adding equivalent, fully after reaction, remove precipitate, get supernatant, carry except ethanol after distilling under reduced pressure, after carrying out disinfection, obtain the operation of fresh eclipta composition.
In addition, fresh eclipta composition of the present invention can be applied in the hair series of products for raw hair color such as nutrition shampoo, treatment wax, nutritional solution dew.
Invention effect
Fresh eclipta composition of the present invention has following advantage:
1) cell function can be improved rapidly, supplement the nutrients, promote the anabolism of trichochromes cell.
2) pure rarely have the new discovery of machine plants ' medicinal component and novelty teabag, for B16 cell provides comprehensive biological active nutritional element, can really promote and realize white hair and naturally turn black.
3) do not induce other cytometaplasia hypertrophy, also do not make melanocyte increased number, serviceability is safer.
4) not containing any photosensitive and chemical irritants, existing medicine photochemical reaction is avoided to the infringement of human body, serviceability milder.
5) definite effect is remarkable, rapid-action, is applicable to the preventing of various poliosis, treats the nutrition with hair color.
6) draw materials extensive, with low cost, environment friendly and pollution-free.
Detailed description of the invention
Below, the production technology of fresh eclipta composition of the present invention and this fresh eclipta composition is specifically described.
Present inventor Liu Zi puts down from the science angle of modern medicine, the theory proposing " phenylalanine, tyrosine are urged human body melanin granule and naturally synthesized " first, has set forth two seed amino acids and trace element to promoting that the positive role of enzyme and kinase activity and melanin granule are to the physiological action of brain nervous cell and the effect to the synthesis of neurotransmitter DOPA.This theory belongs to the important breakthrough of basic medical theory.
Fresh eclipta composition of the present invention has selected diverse pure fresh plant and Chinese medicine species with Chinese medicine, with the extraction process of original creation, preserve the biological activity of the important substance such as enzyme, kinases, phenylalanine, tyrosine, biological Saponin, ATP to greatest extent.
Fresh eclipta composition of the present invention comprises fresh Herba Ecliptae extracting solution (A), fresh Herba Portulacae extracting solution (B), fresh Folium Camelliae sinensis extracting solution (C), fresh Herba Spinaciae extracting solution (E), Radix Rehmanniae extracting solution (D).
Its ratio range of fresh eclipta composition of the present invention is as shown in table 1.
Table 1
Title Content range % Be preferably % Be more preferably % Most preferably be %
Fresh Herba Ecliptae extracting solution 20~70 22~64 28~62 60
Fresh Herba Portulacae extracting solution 10~30 12~28 14~26 15
Fresh Folium Camelliae sinensis extracting solution 7~10 8~9 9~8 5
Fresh Herba Spinaciae extracting solution 3~10 4~9 5~8 5
Radix Rehmanniae extracting solution 10~30 12~25 13~20 15
Note: in table, said content range is volume content.
Manufacture fresh eclipta composition of the present invention and can adopt conventional method extracting solution being carried out mix, extract of the prior art, first composition each in compositions fresh Herba Ecliptae extracting solution, fresh Herba Portulacae extracting solution, fresh Folium Camelliae sinensis extracting solution, Radix Rehmanniae extracting solution, fresh Herba Spinaciae extracting solution are mixed by ormal weight, temperature 22 ~ 24 DEG C, leave standstill 8 days, filter with 300 object gauzes, it is carried out disinfection, is slightly carried mixed liquor.Then, slightly carrying in mixed liquor 95% ethanol adding equivalent, fully after reaction, removing precipitate, get supernatant, carry except ethanol after distilling under reduced pressure, after carrying out disinfection, obtain fresh eclipta composition.
In fresh eclipta composition of the present invention, described fresh Herba Ecliptae extracting solution as a kind of Energy mixture, comprise fresh Herba Ecliptae, Herba Ecliptae dry product, Radix Ginseng, Radix Polygoni Multiflori, Semen Sesami Nigrum and 25% rare alcohol.Its meridian distribution of property and flavor, comprises Liver Channel, kidney channel, and its function is the kidney invigorating, tonifying YIN, hemostasis, and its new function is the synthesis participating in Energy mixture.
The ratio range of described fresh Herba Ecliptae extracting solution is as shown in table 2.
Table 2
Title Content range % Be preferably % Be more preferably % Most preferably be %
Fresh Herba Ecliptae 10~55 15~50 25~40 30
Herba Ecliptae dry product 10~15 9~14 8.5~10 8
Radix Ginseng 5~10 6~9 7~8 8
Radix Polygoni Multiflori 5~10 5.5~9 6.5~7 7
Semen Sesami Nigrum 5~10 5.5~8 6~8 7
25% rare alcohol 20~45 24~45 32~42 40
Note: described content range is quality percent by volume.Raw material calculates by quality, and rare alcohol by volume calculates.
Rare alcohol used in the present invention is medical alcohol.
Fresh Herba Ecliptae extracting solution of the present invention can adopt general biological extraction process of the prior art, first after the fresh Herba Ecliptae of ormal weight and Herba Ecliptae dry product clear water being cleaned, put into 25% rare alcohol, temperature 22 ~ 24 DEG C, soak extraction after 3 ~ 7 days, add Radix Ginseng, Radix Polygoni Multiflori, Semen Sesami Nigrum, temperature 22 ~ 24 DEG C, immersion extraction are after 5 ~ 10 days, get supernatant and leave standstill 48 hours, supernatant is got in discharging, with 300 mesh filter screens filter, after anticorrosion, sterilization, in temperature 22 ~ 24 DEG C storage, for subsequent use.
Poliosis by theory of Chinese medical science for suffer from a deficiency of the kidney relevant, present inventor thinks in its theoretical basis: except old people causes physiological poliosis because the decline of body physiological, cell function, melanin granule can not synthesize, belong to outside category of suffering from a deficiency of the kidney, other more poliosis be then due to work strain, stress is excessive, scalp blood is under-supply, cause that cell function goes down relatively, nutrition supply be not enough and the poliosis that causes hair melanin granule not synthesize and produce.This belongs to, and essence and blood secretly consumes, yin asthenia generating intrinsic heat, bright blood sparkle in the Chinese pathology category of essence.
With regard to fresh Herba Ecliptae extracting solution, because Herba Ecliptae is wherein cool in nature, return liver, kidney two warp, there is effect of the kidney invigorating, tonifying YIN, removing heat from blood, kind purify the blood in heat, therefore have that Herba Ecliptae is kidney tonifying removing heat from blood, crow must hair color, growth hair the saying of key medicine.
Chemical composition contained by this Herba Ecliptae is vitamin A, pellagra preventive factor, and wherein, vitamin A has the effect maintaining epithelial cell stability, and pellagra preventive factor participates in the synthesis of Energy mixture.The present invention is using Herba Ecliptae as the main component in said composition, and by being used as medicine with fresh goods, adopting biological extraction process, more completely can keep the activity of various nutritional labeling, be monarch drug.
And the Radix Ginseng in fresh Herba Ecliptae extracting solution is ministerial drug, it has effect of strongly invigorating QI and blood, and chemical composition is ginsenoside, can blood vessel dilating, improve blood circulation, for cell synthesis energy is provided.
With regard to the Radix Polygoni Multiflori in fresh Herba Ecliptae extracting solution, warm in nature, enter lung spleen kidney three through, liver and kidney tonifying, the benefit that nourishes blood essence, be good at the kind the kidney invigorating deficiency of YIN, but the deficiency of YIN then easily gives birth to interior-heat, Gu Er makes medicine and Herba Ecliptae the monarch and his subjects match as a left side, bring out the best in each other, phospholipid contained by it can blood circulation promoting, promotes the synthesis of cell.
Semen Sesami Nigrum in fresh Herba Ecliptae extracting solution, its property is sweet puts down, enter Liver and kidney, tonification is moisturized, and the nutritional labelings such as the oleic acid contained by it, glyceride and vitamin E more can be moistened hair, make hair more smooth submissive.
In the present invention, by the proportioning of each component in fresh Herba Ecliptae extracting solution being set to the proportioning of each composition in table, thus can realizing not containing any photosensitive and chemical irritants, just can promote the beneficial effect that melanin granule synthesizes naturally.If lower than the lower limit of each composition listed in table, then the optimum efficiency of each component function can not be played, if too high, other component ratio is caused to lack of proper care and can not Comprehensive harmonies be played.
Fresh Herba Portulacae extracting solution in the present invention is made up of fresh Herba Portulacae and 15% rare alcohol.
Fresh Herba Portulacae meridian distribution of property and flavor, comprise large intestine, liver, spleen, its function is: heat-clearing and toxic substances removing, treatment dysentery, erysipelas, contained chemical composition is aminoacid, glutamic acid and vitamin, and its new function is: amino acid contained is the necessary aminoacid of synthesizing black crude granule, and vitamin participates in enzyme and kinase whose anabolism.
The proportioning of fresh Herba Portulacae extracting solution is in the present invention as shown in table 3:
Table 3
Title Content range % Be preferably % Be more preferably % Most preferably be %
Fresh Herba Portulacae 10~80 15~75 25~65 30
15% rare alcohol 20~90 25~85 35~75 70
Note: described content range is quality percent by volume.Raw material calculates by quality, and rare alcohol by volume calculates.
Fresh Herba Portulacae extracting solution of the present invention can adopt common extracting method of the prior art, first after fresh Herba Portulacae clear water being cleaned, put into 15% rare alcohol, after 24 hours, extrude juice with juice extractor in temperature 22 ~ 24 DEG C, immersion, with gauze, be preferably 21 yarns to filter, leave standstill after 24 hours, supernatant is got in discharging, with 300 mesh filter screens filter, to be kept at temperature be 22 ~ 24 DEG C after anticorrosion, sterilization, for subsequent use.
The proportioning of the present invention by by fresh Herba Portulacae extracting solution being above-mentioned table 3, thus effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds can be played, because it is rich in a large amount of aminoacid, vitamin, fat and protein, the synthesis of protein therefore can be participated in.
In fresh eclipta composition of the present invention, described fresh Folium Camelliae sinensis extracting solution is a kind of category-A enzyme agonist, is made up of fresh Folium Camelliae sinensis and deionized water.
This fresh Folium Camelliae sinensis meridian distribution of property and flavor, comprise lung, stomach warp, its function is: reduce phlegm, heat clearing away, and contained chemical composition is pellagra preventive factor, and its new function is: the synthesis participating in enzyme and protein, participates in the synthesis of Energy mixture.
The proportioning of described fresh Folium Camelliae sinensis is as shown in table 4.
Table 4
Title Content range % Be preferably % Be more preferably % Most preferably be %
Fresh Folium Camelliae sinensis (green tea) 10~80 20~60 25~50 30
Deionized water 20~90 40~80 50~75 70
Note: described content range is quality percent by volume.Raw material calculates by quality, and rare alcohol by volume calculates.
The fresh Folium Camelliae sinensis used in the present invention for commercially available any one organic green-tea, such as, can enumerate Xihu Longjing Tea, C.sinensis cv.Huimingcha, dongting biluchun (tea), Gu small piece of land surrounded by water purple tea, noon celestial milli, Yellow Mountain fuzz tip, XINYANGMAOJIAN, par green tea, precious big vast tea, Shangrao white-browed, footpath Flos Camelliae Japonicae, high eyebrow Folium Bambusae etc.In addition, the fresh and tender green tea of fresh Folium Camelliae sinensis preferably before Clear and Bright then.
Fresh Folium Camelliae sinensis extracting solution of the present invention can adopt common extracting method of the prior art, after first being cleaned with clear water by fresh Folium Camelliae sinensis, puts into container, in temperature 22 ~ 24 DEG C, immersion after 2 ~ 18 hours, extrude juice with juice extractor, then use gauze, after preferably 21 yarns filter, leave standstill 24 hours, supernatant is got in discharging, with 300 mesh filter screens filter, anticorrosion, sterilization after, being kept at temperature is 22 ~ 24 DEG C, for subsequent use.
The proportioning of the present invention by by the proportioning of bud green tea extract being each composition of table 4, thus effect of heat-clearing and toxic substances removing can be played, and bud green Folium Camelliae sinensis is containing alkaloid, has direct dilating effect to peripheral vessel.
In fresh eclipta composition of the present invention, described Radix Rehmanniae extracting solution is made up of the medical alcohol of Radix Rehmanniae and 25 ~ 50% concentration.This Radix Rehmanniae meridian distribution of property and flavor, comprises the heart, liver, kidney channel, and its function is: nourish blood, YIN nourishing is new, and its new function is: participate in anabolism.
The proportioning of described Radix Rehmanniae extracting solution is as shown in table 5.
Table 5
Title Content range % Be preferably % Be more preferably % Most preferably be %
Radix Rehmanniae 10~80 15~60 25~45 30
25 ~ 50% medical alcohols 20~90 40~85 55~75 70
Note: described content range is quality percent by volume.Raw material calculates by quality, and rare alcohol by volume calculates.。
Radix Rehmanniae extracting solution of the present invention can adopt common extracting method of the prior art, Radix Rehmanniae clear water is cleaned, put into container, temperature 22 ~ 24 DEG C, add medical alcohol immersion after 3 ~ 48 hours, with gauze, be preferably 21 yarns to filter, leave standstill after 24 hours, supernatant is got in discharging, filters with 300 mesh filter screens, anticorrosion, sterilization, at temperature is 22 ~ 24 DEG C store, for subsequent use.
The proportioning of the present invention by by the proportioning of Radix Rehmanniae extracting solution being each composition of above-mentioned table 5, thus can realisation sweet cool, enter conscience kidney four through, nourishing YIN and benefiting blood benefiting kidney-essence, effect of outstanding kind tonifying kidney-yin.The recovery that it is amino acid contained, alkaloid and fatty acid nutrient substance are biological cells and tissues provides support.
In fresh eclipta composition of the present invention, described fresh Herba Spinaciae extracting solution is a kind of category-B enzyme agonist, is made up of fresh Herba Spinaciae and deionized water.
Fresh Herba Spinaciae meridian distribution of property and flavor, comprise stomach, intestinal warp, its function is: nourish blood, stop blooding, and contained chemical composition is iron ion, each biostearin and folic acid, and its new function is: participate in anabolism.
The proportioning of described fresh Herba Spinaciae extracting solution is as shown in table 6.
Table 6
Title Content range % Be preferably % Be more preferably % Most preferably be %
Fresh Herba Spinaciae 30~70 38~60 45~65 50
Deionized water 30~70 40~62 35~55 50
Note: described content range is quality percent by volume.Raw material calculates by quality, and rare alcohol by volume calculates.
Fresh Herba Spinaciae extracting solution of the present invention can adopt common extracting method of the prior art, after being cleaned by fresh Herba Spinaciae, puts into container with clear water, at temperature 22 ~ 24 DEG C, after adding deionized water Homogeneous phase mixing, extruding juice, with gauze, be preferably 21 yarns to filter, leave standstill after 24 hours, supernatant is got in discharging, filters with 300 mesh filter screens, anticorrosion, sterilization is 22 ~ 24 DEG C of storages, for subsequent use in temperature.
The present invention by by the proportioning of the proportioning of fresh Herba Spinaciae extracting solution for composition each shown in table 6, thus can realize into stomach, intestinal through, effect of nourishing blood, stopping blooding, and contained each biostearin, folic acid participate in cellular metabolism.
In addition, the present invention is said freshly to be referred to, not through the raw material of any processed, carries out processed picking within 24 hours.
Although fresh eclipta composition of the present invention is based on the principles of formulating prescriptions of traditional " monarch " of the traditional Chinese medical science, but not exclusively stick to this, the maximum different of monarch drug taking Radix Polygoni Multiflori as hair color the kidney invigorating from tradition are, deficiency-heat in removing summer-heat blood and solution are allowanced for bark exterior-heat poison combine, residence removing heat from blood is among nourishing blood.From the angle of modern medicine, meet hair color and recover necessary condition, namely, improve blood circulation, recover cell viability, enrich histotrophic nutrition.Meanwhile, take and concoct diverse ways with Chinese medicine, be used as medicine with fresh goods, adopt biological extraction process more completely to maintain the activity of various nutritional labeling.Thus, fresh eclipta composition of the present invention, can not contain any photosensitive and chemical irritants, just can promote naturally synthesizing of human body melanin granule.
Fresh eclipta composition of the present invention can be applied in the hair series of products that nutrition shampoo, treatment wax, nutritional solution dew etc. recover for growth-promoting hair color.
Embodiment
Below, fresh eclipta composition of the present invention is further illustrated by embodiment and comparative example.Rare alcohol used in the present embodiment all by volume percentage ratio calculates.
Embodiment 1
By fresh Herba Ecliptae extracting solution, fresh Herba Portulacae extracting solution, fresh Folium Camelliae sinensis extracting solution, fresh Herba Spinaciae extracting solution, Radix Rehmanniae extracting solution by volume for 2:3:1:1:3 mixes, temperature 23 DEG C, leave standstill 8 days, filter with 300 object gauzes, carry out disinfection, slightly carried mixed liquor.Then, slightly carrying in mixed liquor 95% ethanol adding equivalent, fully after reaction, removing precipitate, get supernatant, carry except ethanol after distilling under reduced pressure, after carrying out disinfection, obtain fresh eclipta composition A.
For fresh Herba Ecliptae extracting solution, after fresh for 30g Herba Ecliptae and 8g Herba Ecliptae dry product clear water are cleaned, put into 25% rare alcohol of 100 milliliters, temperature 23 DEG C, soak extraction after 3 days, add 8g Radix Ginseng, 7g Radix Polygoni Multiflori, 7g Semen Sesami Nigrum, then, again at temperature 23 DEG C, soak extraction after 7 days, get supernatant, leave standstill after 48 hours, supernatant is got in discharging, with 300 mesh filter screens filtrations, anticorrosion, sterilization.
3g fresh Herba Portulacae is put into 15% rare alcohol of 7ml, extract and obtain fresh Herba Portulacae extracting solution.The fresh organic green-tea (Yellow Mountain fuzz tip) of 3g and the deionized water of 7ml are extracted, manufactures fresh Folium Camelliae sinensis extracting solution.Radix Rehmanniae extracting solution of the present invention is made by the medical alcohol of 40% concentration of 3g Radix Rehmanniae and 7ml.With the deionized water of the fresh Herba Spinaciae of 5g and 5ml, make the fresh Herba Spinaciae extracting solution used in the present invention.
Embodiment 2:
Except the volume ratio of fresh Herba Ecliptae extracting solution, fresh Herba Portulacae extracting solution, fresh Folium Camelliae sinensis extracting solution, fresh Herba Spinaciae extracting solution and Radix Rehmanniae extracting solution is changed to except 7:1:0.7:0.3:1, manufacture fresh eclipta composition similarly to Example 1, obtain fresh eclipta composition B.
Embodiment 3
Except the volume ratio of fresh Herba Ecliptae extracting solution, fresh Herba Portulacae extracting solution, fresh Folium Camelliae sinensis extracting solution, fresh Herba Spinaciae extracting solution and Radix Rehmanniae extracting solution is changed into except 6:1.5:0.5:0.5:1.5 respectively, manufacture fresh eclipta composition similarly to Example 1, obtain fresh eclipta composition C.
(1) animal effect experimental
In order to the effect of fresh eclipta composition of the present invention is described, fresh eclipta composition of the present invention is carried out to the zoopery of rabbit tragus melanin granule synthesis.
First, be one group with 6 rabbit, shave off the tragus of the wide ear table of its auris dextra respectively, then, uniform application fresh eclipta composition A of the present invention, B, C respectively, and left ear need not any medicinal liquid, contrasts as consubstantiality.Medication, after 60 days, by sacrifice of animal, as Herba Ecliptae group, gets the hard of hearing skin of rabbit, observes melanin and occurs speed and contain the ratio of volume melanin hair shaft in hair shaft sum.
In contrast, equally to rabbit 6, smear 15% alcohol solvent, and do not smear fresh eclipta composition of the present invention, administration and processing method process are with Herba Ecliptae group of the present invention.
(1) rabbit melanin be there is to the impact of speed:
Shaving hair the 8th day, its medication ear of rabbit of fresh Herba Ecliptae group (using embodiment 1 ~ 3) all starts to occur point-like melanin pigmentation, 15-18 days, and large stretch of melanin pigmentation then appears in medication ear, and non-medication ear also has point-like melanin pigmentation to occur.
In contrast, matched group ears are showed no melanin pigmentation.
(2) pore place is observed containing the ratio of the melanic hair shaft of volume in hair shaft sum by Histological section:
The synthesis of hair melanin granule is relevant with the growth cycle of melanocytic function and hair.How many this experiments represents with melanin amount in hair shaft is in asynchronous hair.Thus understand the effect of fresh eclipta composition to the female chromatophorous nutrition of hair and functional rehabilitation.
The results are shown in table 7.
Table 7
Containing volume melanin hair shaft ratio (X ± SD) in hair shaft sum
Embodiment 1 0.461±0.235
Embodiment 2 0.457±0.251
Embodiment 3 0.476±0.279
Matched group 0.047±0.030
From the experimental result of table 7, in the animal hair shaft of embodiment 1-3, melanin is more, and pigment time of occurrence is obviously faster than matched group rabbit.
(2) human body effect experimental:
In order to prove the facilitation that " fresh eclipta composition " of the present invention synthesizes naturally to human hair melanin granule, the result of use of having carried out the white originator of male, women 2-12 month is observed.
Effective: after use, have newborn hair color or the black tip of root white naturally turn melanotrichia growth, hair color development deepens or interval time of having hair dyed comparatively uses front prolongation, and hair quality improves obviously.
Invalid: not to be any change after use.
The results are shown in table 8.
Table 8
As can be known from the results of Table 8: " the fresh eclipta composition " of the present invention of embodiment 1 ~ 3, promotion human hair pigment granule is naturally synthesized and played a role to the nutrition of hair color, this result also show poliosis and naturally turns black effective time and do not have inevitable contacting and rule between sex, age and medication, and have certain relation with the individual variation of patient and pathogenic factor, in user, all there is not side effect.

Claims (7)

1. a fresh eclipta composition, it is characterized in that, be made up of fresh Herba Ecliptae extracting solution (A), fresh Herba Portulacae extracting solution (B), fresh Folium Camelliae sinensis extracting solution (C), fresh Herba Spinaciae extracting solution (E) and Radix Rehmanniae extracting solution (D); Wherein, the content of described fresh Herba Ecliptae extracting solution (A) is 20 ~ 70%, the content of described fresh Herba Portulacae extracting solution (B) is 10 ~ 30%, the content of described fresh Folium Camelliae sinensis extracting solution (C) is 7 ~ 10%, the content of described fresh Herba Spinaciae extracting solution (E) is 3 ~ 10%, and the content of described Radix Rehmanniae extracting solution (D) is 10 ~ 30%;
Described fresh Herba Ecliptae extracting solution (A) by fresh Herba Ecliptae, Herba Ecliptae dry product, Radix Ginseng, Radix Polygoni Multiflori, Semen Sesami Nigrum and 25% medical alcohol make; The content of described fresh Herba Ecliptae is 10 ~ 55%, the content of described Herba Ecliptae dry product is 10 ~ 15%, and the content of described Radix Ginseng is 5 ~ 10%, and the content of described Radix Polygoni Multiflori is 5 ~ 10%, the content of described Semen Sesami Nigrum is 5 ~ 10%, and the content of the medical alcohol of described 25% is 20 ~ 45%;
Described fresh Herba Portulacae extracting solution is made up of fresh Herba Portulacae and 15% medical alcohol; The content of described fresh Herba Portulacae is 10 ~ 80%, and the content of described 15% medical alcohol is 20 ~ 90%;
Described fresh Folium Camelliae sinensis extracting solution (C) is made up of fresh Folium Camelliae sinensis and deionized water; The content of described fresh Folium Camelliae sinensis is 10 ~ 80%, and the content of described deionized water is 20 ~ 90%;
Described Radix Rehmanniae extracting solution is made up of the medical alcohol of Radix Rehmanniae and 25 ~ 50% concentration; The content of described Radix Rehmanniae is 10 ~ 80%, and the content of the medical alcohol of described 25-50% concentration is 20 ~ 90%;
Described fresh Herba Spinaciae extracting solution is made up of Herba Spinaciae and deionized water; The content of described Herba Spinaciae is 30 ~ 70%, and the content of described deionized water is 30 ~ 70%;
The production technology of described fresh eclipta composition, comprising:
By fresh Herba Portulacae extracting solution, fresh Folium Camelliae sinensis extracting solution, fresh Herba Ecliptae extracting solution, Radix Rehmanniae extracting solution, the mixing of fresh Herba Spinaciae extracting solution, temperature 22 ~ 24 DEG C, leave standstill 8 days, filter with 300 object gauzes, it is carried out disinfection, slightly put forward the operation of mixed liquor; With
Slightly carrying in mixed liquor 95% ethanol adding equivalent, fully after reaction, removing precipitate, get supernatant, carry except ethanol after distilling under reduced pressure, after carrying out disinfection, obtain the operation of fresh eclipta composition.
2. fresh eclipta composition according to claim 1, wherein, the content of described fresh Herba Portulacae is 30%, and the content of described 15% medical alcohol is 70%.
3. fresh eclipta composition according to claim 1, wherein, the content of described fresh Folium Camelliae sinensis is 30%, and the content of described deionized water is 70%.
4. fresh eclipta composition according to claim 1, wherein, the content of described Radix Rehmanniae is 30%, and the content of the medical alcohol of described 25 ~ 50% concentration is 70%.
5. fresh eclipta composition according to claim 1, wherein, the content of described Herba Spinaciae is 50%, and the content of deionized water is 50%.
6. a production technology for the fresh eclipta composition according to any one of manufacturing claims 1 ~ 5, is characterized in that, comprising:
By fresh Herba Portulacae extracting solution, fresh Folium Camelliae sinensis extracting solution, fresh Herba Ecliptae extracting solution, Radix Rehmanniae extracting solution, the mixing of fresh Herba Spinaciae extracting solution, temperature 22 ~ 24 DEG C, leave standstill 8 days, filter with 300 object gauzes, it is carried out disinfection, slightly put forward the operation of mixed liquor; With
Slightly carrying in mixed liquor 95% ethanol adding equivalent, fully after reaction, removing precipitate, get supernatant, carry except ethanol after distilling under reduced pressure, after carrying out disinfection, obtain the operation of fresh eclipta composition.
7. the application of the fresh eclipta composition according to any one of Claims 1 to 5 in preparation nutrition shampoo, treatment wax, nutritional solution dew.
CN201210215999.2A 2012-06-26 2012-06-26 Fresh eclipta composition Active CN103505386B (en)

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CN1543925A (en) * 2003-11-20 2004-11-10 李明劲 Shampoo cream containing Yerbadetajo Herb and method for preparing the same
CN101933984A (en) * 2010-09-29 2011-01-05 湖南省永佳阿胶制药有限公司 Liniment formula for blackening hair and preventing hair loss and preparation and using methods thereof
CN102274473A (en) * 2011-07-15 2011-12-14 广州市娇兰化妆品有限公司 Compound natural plant hair loss preventing liquid and preparation method and application thereof in shampoo liquid

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1543925A (en) * 2003-11-20 2004-11-10 李明劲 Shampoo cream containing Yerbadetajo Herb and method for preparing the same
CN101933984A (en) * 2010-09-29 2011-01-05 湖南省永佳阿胶制药有限公司 Liniment formula for blackening hair and preventing hair loss and preparation and using methods thereof
CN102274473A (en) * 2011-07-15 2011-12-14 广州市娇兰化妆品有限公司 Compound natural plant hair loss preventing liquid and preparation method and application thereof in shampoo liquid

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