CN103479911B - A kind of Chinese medicine composition for the treatment of apoplexy sequela - Google Patents
A kind of Chinese medicine composition for the treatment of apoplexy sequela Download PDFInfo
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- CN103479911B CN103479911B CN201310410321.4A CN201310410321A CN103479911B CN 103479911 B CN103479911 B CN 103479911B CN 201310410321 A CN201310410321 A CN 201310410321A CN 103479911 B CN103479911 B CN 103479911B
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Abstract
The present invention discloses a kind of Chinese medicine composition for the treatment of apoplexy sequela, and said composition is made up of Rhizoma Gastrodiae, Calculus Bovis, Rhizoma Pinelliae Preparata, Rhizoma Acori Graminei, Caulis Bambusae In Taenia, Arisaema Cum Bile, Fructus Trichosanthis, Fel Ursi, Radix Scrophulariae, Monas cuspurpureus Went, Radix Polygalae, Cinnabaris, Bombyx Batryticatus, Borneolum Syntheticum, Pheretima, Fructus Gleditsiae Abnormalis, Radix Ginseng Rubra, Agkistrodon, Zaocys, Os Tigris, Scorpio, Radix Ginseng, Carapax et Plastrum Testudinis, Moschus, Cornu rhinocerotis and Benzoinum.Pharmaceutical composition of the present invention conveniently technique adds customary adjuvant and makes the pill of clinical acceptance, capsule, tablet, granule, powder, decoction or oral liquid.Pharmaceutical composition of the present invention has that peace consciousness-restoring and orifice-opening, refreshing sedate, strengthening vital QI to eliminate pathogenic factors, YIN nourishing spleen invigorating, regulating the flow of vital energy are strongly fragrant, effect of brain-strengthening kidney tonifying.To treatment apoplexy sequela Be very effective, have no side effect.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of Chinese medicine composition for the treatment of apoplexy sequela.
Background technology
Apoplexy is also apoplexy, is the general designation of Chinese medicine to acute cerebrovascular disease.It is suddenly fainted, syncope, the distortion of commissure that occurs together, dysphonia and occur that hemiplegia is a class disease of cardinal symptom.Because primary disease sickness rate is high, mortality rate is high, disability rate is high, relapse rate is high and complication is many, so medical circle is listed as one of three large diseases threatening human health its same coronary heart disease, cancer.The importance of prevention of stroke has caused the attention of domestic and international medical circle, and physicians explore the preventive measure of apoplexy just in all its bearings.Though have a lot of Chinese patent drugs for treatment apoplexy at present, effect is not very remarkable.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine composition for the treatment of apoplexy sequela.
The present invention is achieved through the following technical solutions:
The crude drug of Chinese medicine composition of the present invention consists of:
The crude drug composition of Chinese medicine composition of the present invention is preferably:
The crude drug composition of Chinese medicine composition of the present invention is preferably:
The crude drug composition of Chinese medicine composition of the present invention is preferably:
Chinese medicine composition of the present invention conveniently technique adds customary adjuvant and makes the pill of clinical acceptance, capsule, tablet, granule, powder, decoction or oral liquid.
Chinese medicine composition of the present invention has that peace consciousness-restoring and orifice-opening, refreshing sedate, strengthening vital QI to eliminate pathogenic factors, YIN nourishing spleen invigorating, regulating the flow of vital energy are strongly fragrant, effect of brain-strengthening kidney tonifying.To treatment apoplexy sequela Be very effective, have no side effect.
Experimental example is used for further illustrating the present invention below, but is not limited to the present invention.
One, experimental example
1, clinical observation
Treatment group anthology invention capsule (according to the preparation of embodiment 1 method) treatment apoplexy sequela 100 example, wherein male 50 example, women 50 example.
2, medicament selection
Treatment group: capsule of the present invention (according to the preparation of embodiment 1 method), treats three courses for the treatment of (15 days courses for the treatment of), oral, every 0.5g.Each serving 4, every day 2 times.
3, diagnostic criteria
1. with hemiplegia, crooked mouth and tongue, stiff tongue speech stuttering, hemianesthesia, very then staring spells, mist, coma, muddle-headed be main symptom.
2. fall ill hurried, have progressive evolution.There is dizziness headache, the tendencys such as numb limbs and tense tendons before sick more.
3. often have worn with age, overstrain internal injury, hobby tobacco and wine, the factors such as rich and fatty diet.Often bring out because angry, tired, excessive drinking, sense are cold etc.
4. blood pressure, nervous system, cerebrospinal fluid and the inspection such as routine blood test, optical fundus is done.CT, magnetic resonance examination, can have Novel presentation.
4, criterion of therapeutical effect
" in cure the desease Standardization of diagnosis and curative effect " of implementing with reference to State Administration of Traditional Chinese Medicine 1994 drafts as follows:
Recovery from illness: tcm clinical practice symptom, sign disappear or substantially disappear;
Effective: tcm clinical practice symptom, sign obviously change;
Effective: tcm clinical practice symptom, sign all take a favorable turn;
Invalid: tcm clinical practice symptom, sign are all not improved;
5, therapeutic outcome
The efficacy result of apoplexy sequela treated by table 1
| Group | Treatment number | Cure | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 100 | 60 | 18 | 20 | 2 | 98％ |
6, conclusion
Capsule of the present invention (according to the preparation of embodiment 1 method) treatment apoplexy sequela three courses for the treatment of (15 days each courses for the treatment of), therapeutic outcome shows, and total effective rate is 98%.
7, discuss
Rhizoma Gastrodiae in Chinese medicine composition of the present invention: Gan Ping, returns Liver Channel.Effect: endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral.Calculus Bovis: the cholelithiasis referring to bovid cattle or Babalus bubalis L..Hardship, cool.GUIXIN, Liver Channel.Function cures mainly: clear away heart-fire, and eliminating phlegm is had one's ideas straightened out, cool liver, endogenous wind stopping, removing toxic substances.The clearing away heart-fire and eliminating phlegm of this product energy, refreshment of having one's ideas straightened out, for epidemic febrile disease heat attacking the pericardium, unconsciousness and delirium, or the expectorant thermal resistance such as apoplexy, infantile convulsion, epilepsy is closed.Rhizoma Pinelliae Preparata: pungent, temperature.Return spleen, stomach, lung meridian.Function cures mainly: drying dampness to eliminate phlegm.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache.Rhizoma Acori Graminei: nature and flavor: warm in nature, acrid in the mouth, hardship.This product is pungent to be opened bitter dry temperature and leads to, and fragrance is walked to alter, and not only has the merit of refreshment of having one's ideas straightened out, and has removing dampness concurrently, eliminating phlegm, wards off dirty effect.Caulis Bambusae In Taenia: nature and flavor: cold nature, sweet in the mouth.Return lung, stomach warp.Function cures mainly: removing heat-phlegm, relieves restlessness and prevents vomiting.Arisaema Cum Bile: be the processed goods of Rhizoma Arisaematis Fel Bovis seu Bubali mixing.Taste is micro-pungent and bitter, cool in nature.Enter the heart, liver, lung three warp.Function cures mainly: clearing away fire and eliminating phlegm, relieving convulsion fixed chronic.Control middle wind-phlegm fan, infantile convulsion epilepsy, phlegm-fire is breathed heavily and is coughed, phlegm-accumulating vertigo." medicineization justice ": " cure mainly all apoplexy, acute infantile convulsion, infantile convulsion, wind syndrome of head, dizzy, old god is slow-witted, and children's sends out and jerks, puerperal severe palpitation.Fructus Trichosanthis: sweetness and bitterness, cold.Enter lung, stomach, large intestine channel." herbal classic is met former ": " Fructus Trichosanthis is real, and its property comparatively radices trichosanthis is slightly flat, and without cold strongly fragrant trouble." Fel Ursi: bitter, cold.Return liver; Gallbladder; The heart; Stomach warp.Function cures mainly: heat-clearing and toxic substances removing, improving eyesight, relieving convulsion.Be applicable to excessive heat of infant infantile convulsion, epilepsy, twitch.Radix Scrophulariae: bitter in the mouth is salty.Cold nature.Nontoxic.Function cures mainly: replenishing YIN and removing heat, eliminating fire and detoxication, hard masses softening and resolving.Monas cuspurpureus Went: sweet, warm, nontoxic.Return liver; Spleen; Stomach; Large intestine channel.Function cures mainly: blood circulation promoting and blood stasis dispelling; Strengthening the spleen to promote digestion.Main eating accumulation; Distension and fullness in the abdomen.Radix Polygalae: warm in nature, bitter in the mouth, pungent, the function of there is Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, subsiding a swelling.Cinnabaris: nature and flavor: cold nature, sweet in the mouth, can not be excessive or continue to take, in case mercurialism.Pharmacological action: tranquilizing mind, heat-clearing and toxic substances removing.Arisaema Cum Bile: bitter cold, micro-pungent, cool.Return lung, liver, spleen channel.Removing heat-phlegm, dispelling wind and relieving convulsion.For middle wind-phlegm fan, demented infantile convulsion.Bombyx Batryticatus: be conventional Chinese medicine simply, acrid in the mouth, salty, property is put down, and have expelling wind to relieve convulsion, dissipating phlegm and resolving masses, effect of heat-clearing and toxic substances removing dampness, clinical being used for controls heat syndrome cough, rheumatalgia etc., and its range of application and field constantly expand in recent years.Borneolum Syntheticum: " bitter in the mouth is pungent, tepor, nontoxic." enter the heart, Liver Channel.Treatment apoplexy locked mouth, infantile convulsion expectorant fan.Pheretima: cold in nature, salty in the mouth.Heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis; Twitch for unconsciousness due to high fever infantile convulsion, joint is benumbed, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, vascular hypertension.Rhizoma Gastrodiae: Gan Ping, returns Liver Channel.Function: endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral.Clinically be used for the disease such as headache dizzy, numb limbs and tense tendons, infantile convulsion, epilepsy, tic, tetanus.Fructus Gleditsiae Abnormalis: pungent, salty, temperature; Slightly poisonous.Return lung, large intestine channel.Function: eliminate the phlegm and have one's ideas straightened out, mass dissipating and swelling eliminating.For apoplexy locked mouth, remain unconscious, epilepsy abundant expectoration, pass key is obstructed.Radix Ginseng Rubra: nature and flavor: sweet, micro-hardship, temperature.Gui Jing: return spleen, lung, heart channel.Radix Ginseng Rubra is the ripe articles for use of ginseng, has energy strongly invigorating primordial QI, and multiple arteries and veins takes off admittedly, nourishing qi to stop effect.Radix Ginseng Rubra is used for weak body and prostration, cold extremities faint pulse, QI failing to control blood, metrostaxis; Heart failure, cardiogenic shock.Agkistrodon: sweet in the mouth.Salty.Property is put down.Poisonous.Meat: cure mainly apoplexy and numb limbs and tense tendons is meciless, spasm of muscles and vessels, facial hemiparalysis, hemiplegia, arthralgia.Li Shizhen (1518-1593 A.D.) is said: wind being mobile and changeable, and Serpentis also benefaction number sloughs off, and eats Caulis et Folium piperis again, so deeply can search wind, cuts and frightenedly surely to jerk, the key medicine of, stasis of blood tinea malignant boil frightened for migratory arthralgia.Zaocys: sweet is flat.Return Liver Channel.Dispel the wind, dredging collateral, relieving convulsion.Os Tigris: sweet, pungent, temperature.Return liver, kidney channel.It is the skeleton of felid tiger.Os Tigris is one of famous and precious rare animal medical material of China, has benefit essence of reinforcing the kidney, the effect such as strengthening the tendons and bones, Fructus Alpiniae Oxyphyllae are prolonged life, relaxing muscles and tendons to promote blood circulation, promoting blood circulation, strengthening the tendons and bones.Scorpio: pungent, flat; Poisonous.Return Liver Channel.Suppressing the hyperactive liver to relieve the wind syndrome; Dispel-wind drug.There is " spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., antiinflammatory counteracting toxic substances, removing obstruction in the collateral to relieve pain " function.Radix Ginseng: property is flat, sweet in the mouth, micro-hardship, tepor.Return spleen, lung, heart channel.Effect: strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, Fructus Alpiniae Oxyphyllae of calming the nerves.Carapax et Plastrum Testudinis: salty in the mouth is flat.Enter liver, kidney channel.Effect: YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone.Moschus: pungent, temperature, GUIXIN, spleen channel.Function: refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, pain relieving.Cornu rhinocerotis: nature and flavor acid is salty, cold.For antipyretic, heat removing and blood cooling medicine.Function heat clearing away, removing heat from blood, arresting convulsion, removing toxic substances.Benzoinum: pungent, bitter, flat, nontoxic.Effect: refreshment of having one's ideas straightened out; Eliminating phlegm is warded off dirty; Promoting flow of QI and blood; Pain relieving." book on Chinese herbal medicine is stated ": control apoplexy, migratory arthralgia ， Feng Epilepsy.Pharmaceutical composition of the present invention has that consciousness-restoring and orifice-opening, tranquilizing the mind, strengthening vital QI to eliminate pathogenic factors, YIN nourishing spleen invigorating, regulating the flow of vital energy are strongly fragrant, effect of brain-strengthening kidney tonifying.To treatment apoplexy sequela Be very effective, have no side effect.
Experimental example two, model case
Case 1: grandson, female, 63 years old.Peasant.Hemiplegia on the left of apoplexy before 2 years, the acupuncture of can not walking of the frequent edema pain of present left lower extremity has no effect in one month.Tongue is greasy in vain, slippery and rapid pulse.Diagnosis: apoplexy sequela.Method for the treatment of: YIN nourishing spleen invigorating, blood circulation promoting and blood stasis dispelling.By taking capsule of the present invention (according to the preparation of embodiment 1 method) treatment 2 courses for the treatment of (15 days courses for the treatment of), each serving 4, every day 2 times.Left lower extremity edema symptom obviously alleviates, and the state of an illness is clearly better.During further consultation, tongue arteries and veins is the same.Continuous take a course for the treatment of of capsule of the present invention, cure completely.
Case 2: Lee, man, 65 years old.Before 4 years, burst apoplexy, though through rescuing in time, but still leaves serious sequela.The left limb dyskinesia, right upper extremity lifts limited, and hands is unable can not take thing, and perspiration is many, sleeps poor.Diagnosis: apoplexy sequela; Method for the treatment of: tranquilizing the mind, strengthening vital QI to eliminate pathogenic factors.Treat five courses for the treatment of by taking Tablets, patient is conscious, and limb activity is clearly better, and receives food amelioration, peace of sleeping.2 courses for the treatment of (15 days courses for the treatment of) treated by continuous invention tablet (according to the preparation of embodiment 2 method) of taking, and patient activity freely.Cure completely after continuing to strengthen a course for the treatment of.
Case 3: Zhang, female, 68 years old.Peasant.Hemiplegia on the left of apoplexy before 3 years, the frequent edema pain of left lower extremity, can not walk, DeGrain after large hospital treats month.Tongue is greasy in vain, slippery and rapid pulse.Diagnosis: apoplexy sequela.Method for the treatment of: YIN nourishing spleen invigorating, blood circulation promoting and blood stasis dispelling.By taking granule of the present invention (according to the preparation of embodiment 3 method) treatment 2 courses for the treatment of (15 days courses for the treatment of), left lower extremity edema and pain symptom obviously alleviate, and the state of an illness is clearly better.During further consultation, tongue arteries and veins is the same.Continuous take a course for the treatment of of granule of the present invention, cure completely.
Following embodiment all can realize the effect of above-mentioned experimental example.
Embodiment 1 capsule
By said medicine conveniently technique add customary adjuvant and make capsule, every 0.5g.Each serving 4, every day 2 times.
Embodiment 2 tablet
By said medicine conveniently technique add customary adjuvant and make tablet.
Embodiment 3 granule
By said medicine conveniently technique add customary adjuvant and make granule.Embodiment 4 pill
By said medicine conveniently technique add customary adjuvant and make pill.
Embodiment 5 oral liquid
By said medicine conveniently technique add customary adjuvant and make oral liquid.
Claims (5)
1. treat a Chinese medicine composition for apoplexy sequela, it is characterized in that, the crude drug of said composition consists of:
2. Chinese medicine composition as claimed in claim 1, it is characterized in that, the crude drug of said composition consists of:
3. Chinese medicine composition as claimed in claim 1, it is characterized in that, the crude drug of said composition consists of:
4. Chinese medicine composition as claimed in claim 1, it is characterized in that, the crude drug of said composition consists of:
5. the application of the Chinese medicine composition as described in one of claim 1-4 in the medicine of preparation treatment apoplexy sequela.
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| CN106266759A (en) * | 2016-08-16 | 2017-01-04 | 甘肃鑫晟源生物科技开发有限责任公司 | A kind of granule for apoplexy sequela and rheumatic and rheumatoid diseases and preparation method thereof |
| CN116983368A (en) * | 2023-08-17 | 2023-11-03 | 广州新征程生物科技有限公司 | Traditional Chinese medicine for treating apoplexy sequela and preparation method thereof |
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| CN85106091A (en) * | 1985-04-01 | 1986-07-16 | 辽阳制药厂 | Produce the method for anti-embolism regenerative pill |
| CN1256926A (en) * | 1998-12-11 | 2000-06-21 | 孔宪斌 | Pill for treating hemiplegia |
| CN101991814A (en) * | 2009-08-14 | 2011-03-30 | 汤明昌 | Preparation with functions of expelling wind, reducing phlegm, promoting blood circulation and removing obstruction from channels and preparation method |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85106091A (en) * | 1985-04-01 | 1986-07-16 | 辽阳制药厂 | Produce the method for anti-embolism regenerative pill |
| CN1256926A (en) * | 1998-12-11 | 2000-06-21 | 孔宪斌 | Pill for treating hemiplegia |
| CN101991814A (en) * | 2009-08-14 | 2011-03-30 | 汤明昌 | Preparation with functions of expelling wind, reducing phlegm, promoting blood circulation and removing obstruction from channels and preparation method |
Non-Patent Citations (2)
| Title |
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| 中医药治疗中风后遗症研究近况;周志娴;《云南中医学院学报》;20060831;第29卷;149-152 * |
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