CN103479879A - Burn ointment and preparation method thereof - Google Patents
Burn ointment and preparation method thereof Download PDFInfo
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- CN103479879A CN103479879A CN201310381004.4A CN201310381004A CN103479879A CN 103479879 A CN103479879 A CN 103479879A CN 201310381004 A CN201310381004 A CN 201310381004A CN 103479879 A CN103479879 A CN 103479879A
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Abstract
The invention discloses burn ointment. The burn ointment comprises the following active components by weight: 60-80g of cutch, 40-60g of paeonia suffruticosa, 40-60g of mungbean, 20-30g of rhizoma anemarrhenae, 40-60g of fructus forsythiae, 50-70g of sophora flavescens, 40-60g of cape jasmine, 50-70g of notopterygium, 50-70g of aloe, 40-60g of chrysanthemum, 10-20g of cortex lycii radicis, 40-60g of polygonum cuspidatum, 40-60g of bletilla striata, and 30-50g of borneol. The burn ointment can be used for solving the problems of local blood stasis and obstruction, meridian stagnation and toxic heat flourishing, and has good effects in activating blood circulation, removing stasis and dredging collaterals, clearing heat and toxicity and cooling blood, and treating burns, wherein the effective rate is 93.2 percent, and the rate of favorable curative effect is 91.3 percent.
Description
Technical field
The present invention relates to contain the medicinal preparation that derives from plant material, particularly a kind of ointment for treating burn and preparation method thereof.
Background technology
Burn is flame, scorching hot gas, liquid, solid or electricity, lonizing radiation and the acting on human body of chemical substance and a kind of damage of causing.Clinically take flame wound and scalding as common.Due to the cause of disease that causes burn, burn surface area, degree, position and burns victims's age, body constitution difference, its clinical manifestation is also different, and depth of burn calculates and adopts three degree quarterings, i.e. I degree, light degree Ⅱ, dark II degree and III degree.Due to burn degree difference, clinical manifestation is also different.It is less that the I degree is hindered district, and the wound surface flushing is scorching hot, pain, and without vesicle, desquamation recovery from illness in 2-3 days; Superficial bums shows as severe pain, and local flushing, be the vesicle that differs in size, and substrate is evenly red, local hyperesthesia or swelling, and 1-2 week recovery from illness, have pigmentation; The existing pain of dark II kilsyth basalt is blunt, and vesicle is as pale as the diabrosis substrate, and there is the red fleck of different densities in central authorities, after burn 12-24 hour more obvious, 3-4 week healing, have cicatrix; III degree burn performance pain disappears, and without vesicle, skin is wax, and nonelastic or carbonization is hard as leather, and dry rear venae subcutaneae blocks as dendroid, and 2-4 week eschar comes off, and forms granulation wound, mostly needs skin-grafting to heal, and can form cicatrix and scar contracture.Diagnostic point is mainly according to clinical manifestation.Severe patient coordinates biochemical chemical examination, and blood, urine routine test are judged with judgement water and electrolyte disturbance situation, internal organs degree of impairment, infection conditions.Modern medicine is anti symptom treatment to the burn treating principle, as given, takes analgesic, external-use burn ointment or oil preparation etc.; Soda acid burn a large amount of clear water immediately rinses wound surface; At first severe patient is taked to shock and infection measure, press the fluid infusion of fluid infusion as burn formula, increase patient's nutrition, the measures such as blood transfusion, or intramuscular injection gamma globulin in case of necessity.
Chinese medicine claims burn for " burn due to hot liquid or fire ", specifically can be divided into " burning hot wound ", " soup scald ", " burn " etc.The Tang Dynasty Sun Simiao " prescriptions worth thousand gold " and is pointed out, and " all fired damages careful not with cold wash it ", otherwise " burn obtains cold, and steam more gos deep into cream, and bad person's muscles and bones difficulty is recovered ".Dialectical and the prognosis of the bright primary disease of the further lock of the doctor of the Qing Dynasty.As being shown note in " hole body difficult to understand purport ", Chen Erfeng has " soup is scalded ... the lighter's evil is at skin, heavy, at muscle, more so person's evil is at internal organs ", " burning skin ulcer burn all over rescues as deceived person's difficulty; Or burn gently and not blackening person's treatment still all right also.Right burnt roulade of skin, pain is hard to bear, has that 100,000 sides use and does not test the person, with the fire-toxin inside fire attack, control also inadequate, therefore the disease of baked wheaten cake, must inside and outside rule together, the fire-toxin legibility is also ".Aspect etiology and pathogenesis, Chinese medicine thinks, burn is that pyretic toxicity burns and contains damage of skin and superficial muscles, causes the intenseness of heat impairment of YIN, pyretic toxicity inside fire attack, internal organs discord, imbalance between YIN and YANG.Later stage is that malicious heresy is gradually moved back, and prolonged illness causes deficiency of both QI and blood, or the moon injures one's stomach and lose, and therefore all diseases are come out one after another.
Chinese medicine is the rarity in traditional Chinese culture, Chinese medicinal ointment or the folk prescription for the treatment of burn occur crossing very much since ancient times, secret recipe etc.It is simple that the present invention aims to provide a kind of technique, removes local blood stasis internal resistance, and meridians are blocked, and the problem of excessive noxious heat, reach activating blood circulation to dissipate blood stasis and dredge the collateral, heat-clearing and toxic substances removing removing heat from blood, a kind of ointment for treating burn that the treatment burn is effective and preparation method thereof.
summary of the invention:
The object of the invention is to, provide a kind of technique simple, remove local blood stasis internal resistance, meridians are blocked, and the problem of excessive noxious heat, reach activating blood circulation to dissipate blood stasis and dredge the collateral, heat-clearing and toxic substances removing removing heat from blood, a kind of ointment for treating burn that the treatment burn is effective and preparation method thereof.
For solving the problems of the technologies described above, the invention provides a kind of ointment for treating burn, wherein, comprise the following active component according to the unit of weight configuration:
Catechu 60-80g, Cortex Moutan 40-60g, Semen phaseoli radiati 40-60g, Rhizoma Anemarrhenae 20-30g, Fructus Forsythiae 40-60g, Radix Sophorae Flavescentis 50-70g, Fructus Gardeniae 40-60g, Rhizoma Et Radix Notopterygii 50-70g, Aloe 50-70g, Flos Chrysanthemi 40-60g, Cortex Lycii 10-20g, Rhizoma Polygoni Cuspidati 40-60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-60g, Borneolum Syntheticum 30-50g.
Perhaps, comprise the following active component according to the unit of weight configuration:
Catechu 60-70g, Cortex Moutan 40-50g, Semen phaseoli radiati 40-50g, Rhizoma Anemarrhenae 20-25g, Fructus Forsythiae 40-50g, Radix Sophorae Flavescentis 50-60g, Fructus Gardeniae 40-50g, Rhizoma Et Radix Notopterygii 50-60g, Aloe 50-60g, Flos Chrysanthemi 40-50g, Cortex Lycii 10-15g, Rhizoma Polygoni Cuspidati 40-50g, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-50g, Borneolum Syntheticum 30-40g.
Perhaps, comprise the following active component according to the unit of weight configuration:
Catechu 70-80g, Cortex Moutan 50-60g, Semen phaseoli radiati 50-60g, Rhizoma Anemarrhenae 25-30g, Fructus Forsythiae 50-60g, Radix Sophorae Flavescentis 60-70g, Fructus Gardeniae 50-60g, Rhizoma Et Radix Notopterygii 60-70g, Aloe 60-70g, Flos Chrysanthemi 50-60g, Cortex Lycii 15-20g, Rhizoma Polygoni Cuspidati 50-60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 50-60g, Borneolum Syntheticum 40-50g.
Perhaps, comprise the following active component according to the unit of weight configuration:
Catechu 65-75g, Cortex Moutan 45-55g, Semen phaseoli radiati 45-55g, Rhizoma Anemarrhenae 22-28g, Fructus Forsythiae 45-55g, Radix Sophorae Flavescentis 55-65g, Fructus Gardeniae 45-55g, Rhizoma Et Radix Notopterygii 55-65g, Aloe 55-65g, Flos Chrysanthemi 45-55g, Cortex Lycii 12-18g, Rhizoma Polygoni Cuspidati 45-55g, Pseudobulbus Bletillae (Rhizoma Bletillae) 45-55g, Borneolum Syntheticum 35-45g.
Purpose to better implement the present invention, the present invention also provides a kind of preparation method of ointment for treating burn, comprises the steps:
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride, chlorhexidine acetate and glycerol are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain ointment for treating burn.
Advantage of the present invention is: remove local blood stasis internal resistance, meridians are blocked, and the problem of excessive noxious heat, reach activating blood circulation to dissipate blood stasis and dredge the collateral, the heat-clearing and toxic substances removing removing heat from blood, and the treatment burn is effective.Wherein effective percentage 93.2%, rate of good 91.3%.
the specific embodiment:
Embodiment 1
Liu, two burn of lower limb, burn surface area 9%, wound surface burn degree is dark II degree, medical in 4h after burn, use the present invention, catechu 60g, Cortex Moutan 40g, Semen phaseoli radiati 40g, Rhizoma Anemarrhenae 20g, Fructus Forsythiae 40g, Radix Sophorae Flavescentis 50g, Fructus Gardeniae 40g, Rhizoma Et Radix Notopterygii 50g, Aloe 50g, Flos Chrysanthemi 40g, Cortex Lycii 10g, Rhizoma Polygoni Cuspidati 40g, Pseudobulbus Bletillae (Rhizoma Bletillae) 40g, Borneolum Syntheticum 30g.
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride 15g, chlorhexidine acetate 20g and glycerol 20g are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain ointment for treating burn.
Before using, every 250g ointment for treating burn adds approximately 80 of cod-liver oil drop 2.5g(), stir evenly and get final product.
To directly medicine be applied to the up exposure treatment of wound surface after the wound surface debridement, or 1 layer of sterile gauze of enclosing cover capable half exposes treatment; Make regular check on every day under gauze and have or not hydrops, change in time gauze if needed.4d changes dressings once left and right.The 9d healing, the decrustation fully of 18d left and right, form fresh granulation wound.
Embodiment 2
Zhang, trunk extremity burn, burn surface area 17%, depth of burn is light degree Ⅱ, medical in 3h after burn, use the present invention, catechu 65g, Cortex Moutan 45g, Semen phaseoli radiati 45g, Rhizoma Anemarrhenae 22g, Fructus Forsythiae 45g, Radix Sophorae Flavescentis 55g, Fructus Gardeniae 45g, Rhizoma Et Radix Notopterygii 55g, Aloe 55g, Flos Chrysanthemi 45g, Cortex Lycii 12g, Rhizoma Polygoni Cuspidati 45g, Pseudobulbus Bletillae (Rhizoma Bletillae) 45g, Borneolum Syntheticum 35g.
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride 15g, chlorhexidine acetate 20g and glycerol 20g are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain ointment for treating burn.
Before using, every 250g ointment for treating burn adds approximately 80 of cod-liver oil drop 2.5g(), stir evenly and get final product.
To directly medicine be applied to the up exposure treatment of wound surface after the wound surface debridement, or 1 layer of sterile gauze of enclosing cover capable half exposes treatment; Make regular check on every day under gauze and have or not hydrops, change in time gauze if needed.4d changes dressings once left and right.The 4d healing, the decrustation fully of 12d left and right, form fresh granulation wound.
Embodiment 3
Huang, the boiled water shirtfront of burning, burn surface area 12%, the degree of depth is light degree Ⅲ, burn and go to a doctor in latter 2 hours, use the present invention, catechu 75g, Cortex Moutan 55g, Semen phaseoli radiati 55g, Rhizoma Anemarrhenae 28g, Fructus Forsythiae 55g, Radix Sophorae Flavescentis 65g, Fructus Gardeniae 55g, Rhizoma Et Radix Notopterygii 65g, Aloe 65g, Flos Chrysanthemi 55g, Cortex Lycii 18g, Rhizoma Polygoni Cuspidati 55g, Pseudobulbus Bletillae (Rhizoma Bletillae) 55g, Borneolum Syntheticum 45g.
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride 15g, chlorhexidine acetate 20g and glycerol 20g are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain ointment for treating burn.
Before using, every 250g ointment for treating burn adds approximately 80 of cod-liver oil drop 2.5g(), stir evenly and get final product.
To directly medicine be applied to the up exposure treatment of wound surface after the wound surface debridement, or 1 layer of sterile gauze of enclosing cover capable half exposes treatment; Make regular check on every day under gauze and have or not hydrops, change in time gauze if needed.4d changes dressings once left and right.The 14d healing, the decrustation fully of 20d left and right, form fresh granulation wound.
Embodiment 4
Grandson, trunk extremity burn, burn surface area 21%, wound surface burn degree is dark II degree, transfer from one hospital to another so far after 3 days in other hospitalizes after burn, use the present invention, catechu 80g, Cortex Moutan 60g, Semen phaseoli radiati 60g, Rhizoma Anemarrhenae 30g, Fructus Forsythiae 60g, Radix Sophorae Flavescentis 70g, Fructus Gardeniae 60g, Rhizoma Et Radix Notopterygii 70g, Aloe 70g, Flos Chrysanthemi 60g, Cortex Lycii 20g, Rhizoma Polygoni Cuspidati 60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 60g, Borneolum Syntheticum 50g.
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride 15g, chlorhexidine acetate 20g and glycerol 20g are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain ointment for treating burn.
Before using, every 250g ointment for treating burn adds approximately 80 of cod-liver oil drop 2.5g(), stir evenly and get final product.
To directly medicine be applied to the up exposure treatment of wound surface after the wound surface debridement, or 1 layer of sterile gauze of enclosing cover capable half exposes treatment; Make regular check on every day under gauze and have or not hydrops, change in time gauze if needed.4d changes dressings once left and right.The 12d healing, the decrustation fully of 18d left and right, form fresh granulation wound.
Data compare:
220 patients, be divided into treatment group (the present invention) and matched group (moistening ointment for treating burn group) at random.Treatment group 110 examples, male 57 examples, female's 53 examples, at 10 months to 72 years old age, the mean age is (28.69 ± 15.03) year, traumatogenic reason: 60 examples of burning, boiling water burn 48 examples, oil is scalded 2 examples.Burn surface area average out to 12.54 ± 3.60; Matched group 110 examples, male 55 examples, female's 55 examples, at 18 months to 69 years old age, the mean age is (29.26 ± 13.24) year, traumatogenic reason: 53 examples of burning, boiling water burn 44 examples, oil is scalded 3 examples.Burn surface area average out to 10.28 ± 5.60; ).Two groups of ordinary circumstances are relatively without significant difference (P > 0.05), contrast between being organized.
Comparative result, in treatment group, all cases light Ⅱ° is in 3 ~ 7d healing as a result, and depthⅡ° is in 7 ~ 14d healing, and depthⅡ° is in 14 ~ 24d healing, and III degree burn is complete in (20-25) d decrustation, shallow eschar burn 14-18d healing.
Treatment group, than the matched group 2～3d that heals in advance, can make the decrustation fully in 11～17d of II degree wound surface eschar, forms fresh granulation wound, for good basis is established in operation; Can make the infective wound surface inflammation control rapidly, edge of wound is swift in response and disappears, and General Symptoms obviously improves.
For the light Ⅱ° burn and scald, can significantly shorten the course of disease, reduce antibiotic dosage, thus the reduction expense, successful.For the depthⅡ° burn and scald, not only obviously shorten the course of disease, antibiotic use natural law is had to the reduction of certain degree, and significantly reduced the probability of skin grafting.
The present invention removes local blood stasis internal resistance, and meridians are blocked, and the problem of excessive noxious heat, reach activating blood circulation to dissipate blood stasis and dredge the collateral, the heat-clearing and toxic substances removing removing heat from blood, and the treatment burn is effective.Wherein effective percentage 93.2%, rate of good 91.3%.
Claims (5)
1. an ointment for treating burn, is characterized in that, comprises the following active component according to the unit of weight configuration:
Catechu 60-80g, Cortex Moutan 40-60g, Semen phaseoli radiati 40-60g, Rhizoma Anemarrhenae 20-30g, Fructus Forsythiae 40-60g, Radix Sophorae Flavescentis 50-70g, Fructus Gardeniae 40-60g, Rhizoma Et Radix Notopterygii 50-70g, Aloe 50-70g, Flos Chrysanthemi 40-60g, Cortex Lycii 10-20g, Rhizoma Polygoni Cuspidati 40-60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-60g, Borneolum Syntheticum 30-50g.
2. ointment for treating burn according to claim 1, is characterized in that, comprises the following active component according to the unit of weight configuration:
Catechu 60-70g, Cortex Moutan 40-50g, Semen phaseoli radiati 40-50g, Rhizoma Anemarrhenae 20-25g, Fructus Forsythiae 40-50g, Radix Sophorae Flavescentis 50-60g, Fructus Gardeniae 40-50g, Rhizoma Et Radix Notopterygii 50-60g, Aloe 50-60g, Flos Chrysanthemi 40-50g, Cortex Lycii 10-15g, Rhizoma Polygoni Cuspidati 40-50g, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-50g, Borneolum Syntheticum 30-40g.
3. ointment for treating burn according to claim 1, is characterized in that, comprises the following active component according to the unit of weight configuration:
Catechu 70-80g, Cortex Moutan 50-60g, Semen phaseoli radiati 50-60g, Rhizoma Anemarrhenae 25-30g, Fructus Forsythiae 50-60g, Radix Sophorae Flavescentis 60-70g, Fructus Gardeniae 50-60g, Rhizoma Et Radix Notopterygii 60-70g, Aloe 60-70g, Flos Chrysanthemi 50-60g, Cortex Lycii 15-20g, Rhizoma Polygoni Cuspidati 50-60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 50-60g, Borneolum Syntheticum 40-50g.
4. ointment for treating burn according to claim 1, is characterized in that, comprises the following active component according to the unit of weight configuration:
Catechu 65-75g, Cortex Moutan 45-55g, Semen phaseoli radiati 45-55g, Rhizoma Anemarrhenae 22-28g, Fructus Forsythiae 45-55g, Radix Sophorae Flavescentis 55-65g, Fructus Gardeniae 45-55g, Rhizoma Et Radix Notopterygii 55-65g, Aloe 55-65g, Flos Chrysanthemi 45-55g, Cortex Lycii 12-18g, Rhizoma Polygoni Cuspidati 45-55g, Pseudobulbus Bletillae (Rhizoma Bletillae) 45-55g, Borneolum Syntheticum 35-45g.
One kind as arbitrary as claim 1-4 as described in the preparation method of ointment for treating burn, it is characterized in that, comprise the steps:
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder; Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder;
Dyclonine hydrochloride, chlorhexidine acetate and glycerol are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain ointment for treating burn.
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| CN201310381004.4A CN103479879A (en) | 2013-08-28 | 2013-08-28 | Burn ointment and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103933405A (en) * | 2014-05-12 | 2014-07-23 | 朱玉静 | Pharmaceutical composition for treating qi-blood deficiency burn, and preparation method thereof |
| CN105194364A (en) * | 2015-09-06 | 2015-12-30 | 张玉玲 | Medicinal composition for local burn nursing |
| CN105456578A (en) * | 2016-01-15 | 2016-04-06 | 李丽 | Traditional Chinese medicine ointment for treating scars and preparing method thereof |
-
2013
- 2013-08-28 CN CN201310381004.4A patent/CN103479879A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103933405A (en) * | 2014-05-12 | 2014-07-23 | 朱玉静 | Pharmaceutical composition for treating qi-blood deficiency burn, and preparation method thereof |
| CN105194364A (en) * | 2015-09-06 | 2015-12-30 | 张玉玲 | Medicinal composition for local burn nursing |
| CN105456578A (en) * | 2016-01-15 | 2016-04-06 | 李丽 | Traditional Chinese medicine ointment for treating scars and preparing method thereof |
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Application publication date: 20140101 |