CN103446443A - Burn ointment and preparation method thereof - Google Patents

Burn ointment and preparation method thereof Download PDF

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Publication number
CN103446443A
CN103446443A CN2013104011087A CN201310401108A CN103446443A CN 103446443 A CN103446443 A CN 103446443A CN 2013104011087 A CN2013104011087 A CN 2013104011087A CN 201310401108 A CN201310401108 A CN 201310401108A CN 103446443 A CN103446443 A CN 103446443A
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powder
radix
burn
bletillae
rhizoma bletillae
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黎英豪
王寿世
杨萍萍
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黎英豪
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Abstract

The invention discloses burn ointment. The burn ointment is prepared from the following active ingredients in weight unit: 60-80g of acalypha australis, 40-60g of mint, 40-60g of fresh hibiscus flowers, 20-30g of bear gall powder, 40-60g of figwort roots, 50-70g of radix sanguisorbae, 40-60g of astragalus roots, 50-70g of catechu, 50-70g of pomegranate barks, 40-60g of myrrh, 10-20g of talcum, 40-60g of pearl powder, 40-60g of hyacinth bletilla and 30-50g of angelica. The burn ointment has the advantages that the problems of partial blood stasis and internal resistance, meridian stagnation and toxic heat flourishing are solved, the effects of blood circulation invigorating, blood stasis dispelling, collateral dredging, heat clearing, detoxifying and blood cooling are achieved, and the burn treatment effect is good, wherein the effective rate is 93.2% and the good rate is 91.3%.

Description

A kind of burn cream and preparation method thereof
Technical field
The present invention relates to contain the medicinal preparation that derives from plant material, particularly a kind of burn cream and preparation method thereof.
Background technology
Burn is flame, scorching hot gas, liquid, solid or electricity, lonizing radiation and the acting on human body of chemical substance and a kind of damage of causing.Clinically take flame wound and scalding as common.Due to the cause of disease that causes burn, burn surface area, degree, position and burns victims's age, body constitution difference, its clinical manifestation is also different, and depth of burn calculates and adopts three degree quarterings, i.e. I degree, shallow II degree, dark II degree and III degree.Due to burn degree difference, clinical manifestation is also different.It is less that the I degree is hindered district, and the wound surface flushing is scorching hot, pain, and without vesicle, desquamation recovery from illness in 2-3 days; Shallow II degree burn shows as severe pain, and local flushing, be the vesicle that differs in size, and substrate is evenly red, local hyperesthesia or swelling, and 1-2 week recovery from illness, have pigmentation; The existing pain of dark II kilsyth basalt is blunt, and vesicle is as pale as the diabrosis substrate, and there is the red fleck of different densities in central authorities, after burn 12-24 hour more obvious, 3-4 week healing, have cicatrix; III degree burn performance pain disappears, and without vesicle, skin is wax, and nonelastic or carbonization is hard as leather, and dry rear venae subcutaneae blocks as dendroid, and 2-4 week eschar comes off, and forms granulation wound, mostly needs skin-grafting to heal, and can form cicatrix and scar contracture.Diagnostic point is mainly according to clinical manifestation.Severe patient coordinates biochemical chemical examination, and blood, urine routine test are judged with judgement water and electrolyte disturbance situation, internal organs degree of impairment, infection conditions.Modern medicine is anti symptom treatment to the burn treating principle, as given, takes analgesic, ointment for external application for curing burn or oil preparation etc.; Soda acid burn a large amount of clear water immediately rinses wound surface; At first severe patient is taked to shock and infection measure, press the fluid infusion of fluid infusion as burn formula, increase patient's nutrition, the measures such as blood transfusion, or intramuscular injection gamma globulin in case of necessity.
Chinese medicine claims burn for " burn due to hot liquid or fire ", specifically can be divided into " burning hot wound ", " soup scald ", " burn " etc.The Tang Dynasty Sun Simiao " prescriptions worth thousand gold " and is pointed out, and " all fired damages careful not with cold wash it ", otherwise " burn obtains cold, and steam more gos deep into cream, and bad person's muscles and bones difficulty is recovered ".Dialectical and the prognosis of the bright primary disease of the further lock of the doctor of the Qing Dynasty." soup is scalded ... the lighter's evil is at skin, heavy, at muscle, more so person's evil is at internal organs " arranged as Chen Erfeng shows note in " hole body difficult to understand purport ", and " burning skin ulcer burn all over rescues as deceived person's difficulty; Or burn gently and not blackening person's treatment still all right also.Right burnt roulade of skin, pain is hard to bear, has that 100,000 sides use and does not test the person, with the fire-toxin inside fire attack, control also inadequate, therefore the disease of baked wheaten cake, must inside and outside rule together, the fire-toxin legibility is also ".Aspect etiology and pathogenesis, Chinese medicine thinks, burn is that pyretic toxicity burns and contains damage of skin and superficial muscles, causes the intenseness of heat impairment of YIN, pyretic toxicity inside fire attack, internal organs discord, imbalance between YIN and YANG.Later stage is that malicious heresy is gradually moved back, and prolonged illness causes deficiency of both QI and blood, or the moon injures one's stomach and lose, and therefore all diseases are come out one after another.
Chinese medicine is the rarity in traditional Chinese culture, Chinese medicinal ointment or the folk prescription for the treatment of burn occur crossing very much since ancient times, secret recipe etc.It is simple that the present invention aims to provide a kind of technique, removes local blood stasis internal resistance, and meridians are blocked, and the problem of excessive noxious heat, reach activating blood circulation to dissipate blood stasis and dredge the collateral, heat-clearing and toxic substances removing removing heat from blood, a kind of burn cream that the treatment burn is effective and preparation method thereof.
Summary of the invention:
The object of the invention is to, provide a kind of technique simple, remove local blood stasis internal resistance, meridians are blocked, and the problem of excessive noxious heat, reach activating blood circulation to dissipate blood stasis and dredge the collateral, heat-clearing and toxic substances removing removing heat from blood, a kind of burn cream that the treatment burn is effective and preparation method thereof.
For solving the problems of the technologies described above, the invention provides a kind of burn cream, wherein, comprise the following active component according to the unit of weight configuration:
Herba Acalyphae 60-80g, Herba Menthae 40-60g, bright Flos Hibisci Mutabilis 40-60g, Fel Ursi powder 20-30g, Radix Scrophulariae 40-60g, Radix Sanguisorbae 50-70g, Radix Astragali 40-60g, catechu 50-70g, Pericarpium Granati 50-70g, Myrrha 40-60g, Talcum 10-20g, Margarita powder 40-60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-60g, Radix Angelicae Sinensis 30-50g.
Perhaps, comprise the following active component according to the unit of weight configuration:
Herba Acalyphae 60-70g, Herba Menthae 40-50g, bright Flos Hibisci Mutabilis 40-50g, Fel Ursi powder 20-25g, Radix Scrophulariae 40-50g, Radix Sanguisorbae 50-60g, Radix Astragali 40-50g, youngster bitter edible plant 50-60g, Pericarpium Granati 50-60g, Myrrha 40-50g, Talcum 10-15g, Margarita powder 40-50g, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-50g, Radix Angelicae Sinensis 30-40g.
Perhaps, comprise the following active component according to the unit of weight configuration:
Herba Acalyphae 70-80g, Herba Menthae 50-60g, bright Flos Hibisci Mutabilis 50-60g, Fel Ursi powder 25-30g, Radix Scrophulariae 50-60g, Radix Sanguisorbae 60-70g, Radix Astragali 50-60g, youngster bitter edible plant 60-70g, Pericarpium Granati 60-70g, Myrrha 50-60g, Talcum 15-20g, Margarita powder 50-60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 50-60g, Radix Angelicae Sinensis 40-50g.
Perhaps, comprise the following active component according to the unit of weight configuration:
Herba Acalyphae 65-75g, Herba Menthae 45-55g, bright Flos Hibisci Mutabilis 45-55g, Fel Ursi powder 22-28g, Radix Scrophulariae 45-55g, Radix Sanguisorbae 55-65g, Radix Astragali 45-55g, catechu 55-65g, Pericarpium Granati 55-65g, Myrrha 45-55g, Talcum 12-18g, Margarita powder 45-55g, Pseudobulbus Bletillae (Rhizoma Bletillae) 45-55g, Radix Angelicae Sinensis 35-45g.
Purpose to better implement the present invention, the present invention also provides a kind of preparation method of burn cream, comprises the steps:
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride, chlorhexidine acetate and glycerol are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain burn cream.
Advantage of the present invention is: remove local blood stasis internal resistance, meridians are blocked, and the problem of excessive noxious heat, reach activating blood circulation to dissipate blood stasis and dredge the collateral, the heat-clearing and toxic substances removing removing heat from blood, and the treatment burn is effective.Wherein effective percentage 93.2%, rate of good 91.3%.
The specific embodiment:
Embodiment 1
Liu, two burn of lower limb, burn surface area 9%, wound surface burn degree is dark II degree, medical in 4h after burn, use the present invention, Herba Acalyphae 60g, Herba Menthae 40g, bright Flos Hibisci Mutabilis 40g, Fel Ursi powder 20g, Radix Scrophulariae 40g, Radix Sanguisorbae 50g, Radix Astragali 40g, catechu 50g, Pericarpium Granati 50g, Myrrha 40g, Talcum 10g, Margarita powder 40g, Pseudobulbus Bletillae (Rhizoma Bletillae) 40g, Radix Angelicae Sinensis 30g.
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride 15g, chlorhexidine acetate 20g and glycerol 20g are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain burn cream.
Before using, every 250g burn cream adds cod-liver oil drop 2.5g (approximately 80), stirs evenly and gets final product.
To directly medicine be applied to the up exposure treatment of wound surface after the wound surface debridement, or 1 layer of sterile gauze of enclosing cover capable half exposes treatment; Make regular check on every day under gauze and have or not hydrops, change in time gauze if needed.4d changes dressings once left and right.The 9d healing, the decrustation fully of 18d left and right, form fresh granulation wound.
Embodiment 2
Zhang, trunk extremity burn, burn surface area 17%, depth of burn is shallow II degree, medical in 3h after burn, use the present invention, Herba Acalyphae 65g, Herba Menthae 45g, bright Flos Hibisci Mutabilis 45g, Fel Ursi powder 22g, Radix Scrophulariae 45g, Radix Sanguisorbae 55g, Radix Astragali 45g, catechu 55g, Pericarpium Granati 55g, Myrrha 45g, Talcum 12g, Margarita powder 45g, Pseudobulbus Bletillae (Rhizoma Bletillae) 45g, Radix Angelicae Sinensis 35g.
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride 15g, chlorhexidine acetate 20g and glycerol 20g are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain burn cream.
Before using, every 250g burn cream adds cod-liver oil drop 2.5g (approximately 80), stirs evenly and gets final product.
To directly medicine be applied to the up exposure treatment of wound surface after the wound surface debridement, or 1 layer of sterile gauze of enclosing cover capable half exposes treatment; Make regular check on every day under gauze and have or not hydrops, change in time gauze if needed.4d changes dressings once left and right.The 4d healing, the decrustation fully of 12d left and right, form fresh granulation wound.
Embodiment 3
Huang, the boiled water shirtfront of burning, burn surface area 12%, the degree of depth is shallow III degree, burn and go to a doctor in latter 2 hours, use the present invention, Herba Acalyphae 75g, Herba Menthae 55g, bright Flos Hibisci Mutabilis 55g, Fel Ursi powder 28g, Radix Scrophulariae 55g, Radix Sanguisorbae 65g, Radix Astragali 55g, youngster bitter edible plant 65g, Pericarpium Granati 65g, Myrrha 55g, Talcum 18g, Margarita powder 55g, Pseudobulbus Bletillae (Rhizoma Bletillae) 55g, Radix Angelicae Sinensis 45g.
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride 15g, chlorhexidine acetate 20g and glycerol 20g are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain burn cream.
Before using, every 250g burn cream adds cod-liver oil drop 2.5g (approximately 80), stirs evenly and gets final product.
To directly medicine be applied to the up exposure treatment of wound surface after the wound surface debridement, or 1 layer of sterile gauze of enclosing cover capable half exposes treatment; Make regular check on every day under gauze and have or not hydrops, change in time gauze if needed.4d changes dressings once left and right.The 14d healing, the decrustation fully of 20d left and right, form fresh granulation wound.
Embodiment 4
Grandson, trunk extremity burn, burn surface area 21%, wound surface burn degree is dark II degree, transfer from one hospital to another so far after 3 days in other hospitalizes after burn, use the present invention, Herba Acalyphae 80g, Herba Menthae 60g, bright Flos Hibisci Mutabilis 60g, Fel Ursi powder 30g, Radix Scrophulariae 60g, Radix Sanguisorbae 70g, Radix Astragali 60g, catechu 70g, Pericarpium Granati 70g, Myrrha 60g, Talcum 20g, Margarita powder 60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 60g, Radix Angelicae Sinensis 50g.
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride 15g, chlorhexidine acetate 20g and glycerol 20g are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain burn cream.
Before using, every 250g burn cream adds cod-liver oil drop 2.5g (approximately 80), stirs evenly and gets final product.
To directly medicine be applied to the up exposure treatment of wound surface after the wound surface debridement, or 1 layer of sterile gauze of enclosing cover capable half exposes treatment; Make regular check on every day under gauze and have or not hydrops, change in time gauze if needed.4d changes dressings once left and right.The 12d healing, the decrustation fully of 18d left and right, form fresh granulation wound.
Data compare:
220 patients, be divided into treatment group (the present invention) and matched group (moist expose burn ointment group) at random.Treatment group 110 examples, male 57 examples, female's 53 examples, at 10 months to 72 years old age, the mean age is (28.69 ± 15.03) year, traumatogenic reason: 60 examples of burning, boiling water burn 48 examples, oil is scalded 2 examples.Burn surface area average out to 12.54 ± 3.60; Matched group 110 examples, male 55 examples, female's 55 examples, at 18 months to 69 years old age, the mean age is (29.26 ± 13.24) year, traumatogenic reason: 53 examples of burning, boiling water burn 44 examples, oil is scalded 3 examples.Burn surface area average out to 10.28 ± 5.60; ).Two groups of ordinary circumstances, relatively without significant difference (P>0.05), contrast between being organized.
Comparative result, in treatment group as a result the shallow II of all cases ° in 3~7d healing, dark II ° in 7~14d healing, dark II ° in 14~24d healing, III degree burn is complete in (20-25) d decrustation, shallow III ° of burn 14-18d healing.
Treatment group, than the matched group 2~3d that heals in advance, can make the decrustation fully in 11~17d of II degree wound surface eschar, forms fresh granulation wound, for good basis is established in operation; Can make the infective wound surface inflammation control rapidly, edge of wound is swift in response and disappears, and General Symptoms obviously improves.
For shallow II ° burn and scald, can significantly shorten the course of disease, reduce antibiotic dosage, thus the reduction expense, successful.For dark II ° burn and scald, not only obviously shorten the course of disease, antibiotic use natural law is had to the reduction of certain degree, and significantly reduced the probability of skin grafting.
The present invention removes local blood stasis internal resistance, and meridians are blocked, and the problem of excessive noxious heat, reach activating blood circulation to dissipate blood stasis and dredge the collateral, the heat-clearing and toxic substances removing removing heat from blood, and the treatment burn is effective.Wherein effective percentage 93.2%, rate of good 91.3%.

Claims (5)

1. a burn cream, is characterized in that, comprises the following active component according to the unit of weight configuration:
Herba Acalyphae 60-80g, Herba Menthae 40-60g, bright Flos Hibisci Mutabilis 40-60g, Fel Ursi powder 20-30g, Radix Scrophulariae 40-60g, Radix Sanguisorbae 50-70g, Radix Astragali 40-60g, catechu 50-70g, Pericarpium Granati 50-70g, Myrrha 40-60g, Talcum 10-20g, Margarita powder 40-60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-60g, Radix Angelicae Sinensis 30-50g.
2. burn cream according to claim 1, is characterized in that, comprises the following active component according to the unit of weight configuration:
Herba Acalyphae 60-70g, Herba Menthae 40-50g, bright Flos Hibisci Mutabilis 40-50g, Fel Ursi powder 20-25g, Radix Scrophulariae 40-50g, Radix Sanguisorbae 50-60g, Radix Astragali 40-50g, catechu 50-60g, Pericarpium Granati 50-60g, Myrrha 40-50g, Talcum 10-15g, Margarita powder 40-50g, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-50g, Radix Angelicae Sinensis 30-40g.
3. burn cream according to claim 1, is characterized in that, comprises the following active component according to the unit of weight configuration:
Herba Acalyphae 70-80g, Herba Menthae 50-60g, bright Flos Hibisci Mutabilis 50-60g, Fel Ursi powder 25-30g, Radix Scrophulariae 50-60g, Radix Sanguisorbae 60-70g, Radix Astragali 50-60g, catechu 60-70g, Pericarpium Granati 60-70g, Myrrha 50-60g, Talcum 15-20g, Margarita powder 50-60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 50-60g, Radix Angelicae Sinensis 40-50g.
4. burn cream according to claim 1, is characterized in that, comprises the following active component according to the unit of weight configuration:
Herba Acalyphae 65-75g, Herba Menthae 45-55g, bright Flos Hibisci Mutabilis 45-55g, Fel Ursi powder 22-28g, Radix Scrophulariae 45-55g, Radix Sanguisorbae 55-65g, Radix Astragali 45-55g, youngster bitter edible plant 55-65g, Pericarpium Granati 55-65g, Myrrha 45-55g, Talcum 12-18g, Margarita powder 45-55g, Pseudobulbus Bletillae (Rhizoma Bletillae) 45-55g, Radix Angelicae Sinensis 35-45g.
One kind as arbitrary as claim 1-4 as described in the preparation method of burn cream, it is characterized in that, comprise the steps:
It is standby that the Pseudobulbus Bletillae (Rhizoma Bletillae) is ground into fine powder;
Other active components except the Pseudobulbus Bletillae (Rhizoma Bletillae) are cleaned, and cut off, and after pulverizing, cross 80 purpose sieves, obtain Chinese medicine powder,
Dyclonine hydrochloride, chlorhexidine acetate and glycerol are added in distilled water, after heating for dissolving, under constantly stirring, add Chinese medicine powder to stir evenly, be sprinkled into common bletilla, placement is spent the night, after the Pseudobulbus Bletillae (Rhizoma Bletillae) powder swelling, stir evenly, divide and install in 250 milliliters of volumetric flasks, the gland sealing, 110 ℃ of flowing steam sterilizations 30 minutes, obtain burn cream.
CN2013104011087A 2013-08-28 2013-08-28 Burn ointment and preparation method thereof Withdrawn CN103446443A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173749A (en) * 2014-09-10 2014-12-03 吕铝淼 Drug for repairing burn and scald
CN105194364A (en) * 2015-09-06 2015-12-30 张玉玲 Medicinal composition for local burn nursing
RU2647372C1 (en) * 2017-04-17 2018-03-15 Александр Ливиевич Ураков Cream for frostbite prevention
CN109771568A (en) * 2019-02-22 2019-05-21 南阳南石医院 A kind of biological agent and preparation method for inhibiting scar and promoting wound healing

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1432378A (en) * 2002-01-17 2003-07-30 傅元庆 Medicine for treating burns and scalds and its prepn process
CN101912532A (en) * 2010-08-30 2010-12-15 张树仁 External traditional Chinese medicine preparation for treating burns, scalds and frostbite
CN102614358A (en) * 2012-04-09 2012-08-01 张涛 Chinese medicinal liniment for treating burn and scalding

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1432378A (en) * 2002-01-17 2003-07-30 傅元庆 Medicine for treating burns and scalds and its prepn process
CN101912532A (en) * 2010-08-30 2010-12-15 张树仁 External traditional Chinese medicine preparation for treating burns, scalds and frostbite
CN102614358A (en) * 2012-04-09 2012-08-01 张涛 Chinese medicinal liniment for treating burn and scalding

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173749A (en) * 2014-09-10 2014-12-03 吕铝淼 Drug for repairing burn and scald
CN105194364A (en) * 2015-09-06 2015-12-30 张玉玲 Medicinal composition for local burn nursing
RU2647372C1 (en) * 2017-04-17 2018-03-15 Александр Ливиевич Ураков Cream for frostbite prevention
CN109771568A (en) * 2019-02-22 2019-05-21 南阳南石医院 A kind of biological agent and preparation method for inhibiting scar and promoting wound healing

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