CN103479582A - 制备含钙组合物的快速湿聚结方法 - Google Patents
制备含钙组合物的快速湿聚结方法 Download PDFInfo
- Publication number
- CN103479582A CN103479582A CN201310206506.3A CN201310206506A CN103479582A CN 103479582 A CN103479582 A CN 103479582A CN 201310206506 A CN201310206506 A CN 201310206506A CN 103479582 A CN103479582 A CN 103479582A
- Authority
- CN
- China
- Prior art keywords
- calcium
- approximately
- tablet
- granule
- containing compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Abstract
Description
赋形剂 | 浓度(组成的百分比) |
甜味剂 | 5-30,如果存在 |
人造甜味剂 | 0.05-0.3,如果存在 |
调味剂 | 0.1-3,如果存在 |
崩解剂 | 0.5-5,如果存在 |
助流剂和润滑剂 | 0.1-5,如果存在 |
填充剂/稀释剂/粘结剂 | 0.1-40,如果存在 |
成膜剂 | 0.1-5,如果存在 |
膜添加剂 | 0.05-5,如果存在 |
Claims (10)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK200500168 | 2005-02-03 | ||
DKPA200500168 | 2005-02-03 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200680003958XA Division CN101128186B (zh) | 2005-02-03 | 2006-02-02 | 制备含钙组合物的快速湿聚结方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN103479582A true CN103479582A (zh) | 2014-01-01 |
Family
ID=34974580
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200680003958XA Expired - Fee Related CN101128186B (zh) | 2005-02-03 | 2006-02-02 | 制备含钙组合物的快速湿聚结方法 |
CN201310206506.3A Pending CN103479582A (zh) | 2005-02-03 | 2006-02-02 | 制备含钙组合物的快速湿聚结方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200680003958XA Expired - Fee Related CN101128186B (zh) | 2005-02-03 | 2006-02-02 | 制备含钙组合物的快速湿聚结方法 |
Country Status (13)
Country | Link |
---|---|
US (1) | US8808735B2 (zh) |
EP (1) | EP1845950A2 (zh) |
JP (1) | JP5305374B2 (zh) |
CN (2) | CN101128186B (zh) |
AU (1) | AU2006211023B2 (zh) |
CA (1) | CA2644400C (zh) |
EA (1) | EA013867B1 (zh) |
IL (1) | IL184714A0 (zh) |
NO (1) | NO20074480L (zh) |
NZ (1) | NZ556465A (zh) |
UA (1) | UA88943C2 (zh) |
WO (1) | WO2006082501A2 (zh) |
ZA (1) | ZA200705875B (zh) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ556465A (en) * | 2005-02-03 | 2010-10-29 | Nycomed Pharma As | Fast wet-massing method for the preparation of calcium-containing compositions |
CA2621284C (en) * | 2005-09-16 | 2014-05-20 | Novartis Ag | Solid composition comprising water-soluble dietary fiber and calcium lactogluconate |
UY31411A1 (es) * | 2007-10-30 | 2009-05-29 | Composicion orodispersable sin mal olor o mal sabor que comprende acidos grasos poliinsaturados | |
US20110288146A1 (en) * | 2008-11-19 | 2011-11-24 | Nandu Deorkar | Directly compressible granular microcrystalline cellulose based, excipient, manufacturing process and use thereof |
SG171362A1 (en) * | 2008-11-20 | 2011-07-28 | Avantor Performance Mat Inc | Directly compressible high functionality granular dibasic calcium phosphate based co-processed excipient |
EP2468265A3 (en) * | 2010-12-04 | 2013-01-02 | DEEF Pharmaceutical Industries Co. | Homogeneous preparations containing vitamin D |
WO2014018433A1 (en) | 2012-07-25 | 2014-01-30 | 3M Innovative Properties Company | Agglomerated microbiological media |
CN103961688B (zh) * | 2014-04-30 | 2016-05-25 | 湖北神地农业科贸有限公司 | 一种蛋壳源复合柠檬酸钙咀嚼片及其制备方法 |
EA035687B1 (ru) | 2015-06-18 | 2020-07-27 | Эстетра Спрл | Диспергируемая в полости рта единица дозирования, содержащая эстетрольный компонент |
DK3106148T3 (en) | 2015-06-18 | 2018-05-07 | Mithra Pharmaceuticals S A | Orodispersible dosing unit containing an estetrol component |
EP3176222A1 (en) * | 2015-12-01 | 2017-06-07 | Omya International AG | Method for the production of granules comprising surface-reacted calcium carbonate |
KR20220144885A (ko) | 2016-08-05 | 2022-10-27 | 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 | 월경통 및 생리통의 관리방법 |
TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
IT202100030935A1 (it) * | 2021-12-09 | 2023-06-09 | Fidia Farm Spa | Compresse comprendenti condroitin solfato, glucosamina cloridrato e vitamina c per il trattamento di danni cartilaginei, tendinei, ossei |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0265951A2 (en) * | 1986-10-31 | 1988-05-04 | Rhone-Poulenc Basic Chemicals Co. | Granular tricalcium phosphate compositions suitable for direct compression tableting |
US4846409A (en) * | 1986-10-17 | 1989-07-11 | Bayer Aktiengesellschaft | Process for the preparation of granules |
US5108728A (en) * | 1990-03-03 | 1992-04-28 | Bk Ladenburg Gmbh | Process for the production of granulated dicalcium phosphate dihydrate |
WO1996009036A1 (fr) * | 1994-09-23 | 1996-03-28 | Laboratoire Innothera, Societe Anonyme | Association therapeutique vitamino-calcique sous forme galenique unitaire de comprimes, son procede d'obtention et son utilisation |
US5883047A (en) * | 1996-04-03 | 1999-03-16 | Basf Aktiengesellschaft | Granules of hygroscopic, water-soluble products |
WO2000028973A1 (en) * | 1998-11-13 | 2000-05-25 | Nycomed Pharma As | Process for preparing oral calcium compositions |
CN101128186B (zh) * | 2005-02-03 | 2013-07-03 | 奈科明制药有限公司 | 制备含钙组合物的快速湿聚结方法 |
Family Cites Families (27)
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---|---|---|---|---|
CA1279574C (en) * | 1985-04-17 | 1991-01-29 | Jeffrey L. Finnan | Process for lubricating water-soluble vitamin powders |
ES2066092T3 (es) | 1990-11-29 | 1995-03-01 | Wei Ming Pharmaceutical Mfg Co | Coadyuvante para la formacion directa de comprimidos. |
US5204115A (en) | 1990-12-12 | 1993-04-20 | Suomen Xyrofin Oy | Directly compressible xylitol and method |
JPH04235942A (ja) | 1991-01-16 | 1992-08-25 | Hiroshi Nakai | 粉末酢酸カルシウムの顆粒化法 |
JP2995226B2 (ja) | 1992-03-03 | 1999-12-27 | 日本ワイスレダリー株式会社 | カルシウム含有チユアブル錠 |
ZA937277B (en) * | 1992-09-30 | 1994-05-19 | Ascent Pharma Inc | Calsium polycarbophil sprinkle |
US5405623A (en) | 1993-09-22 | 1995-04-11 | Wm. Wrigley Jr. Company | Chewing gum compositions and methods for manufacturing same |
DE4427137B4 (de) | 1993-10-07 | 2007-08-23 | Degussa Gmbh | Fällungskieselsäure |
US20010007863A1 (en) * | 1998-06-18 | 2001-07-12 | Merck & Co., Inc. | Wet granulation formulation for bisphosphonic acids |
US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
DE19617487A1 (de) | 1996-05-02 | 1997-11-06 | Merck Patent Gmbh | Geschmacksverbesserung von Arzneimittelwirkstoffen |
AU733032C (en) | 1996-06-14 | 2002-01-03 | Kyowa Hakko Kirin Co., Ltd. | Intraorally rapidly disintegrable tablet |
FR2762217B1 (fr) | 1997-04-16 | 2000-09-29 | Besins Iscovesco Lab | Preparation solide vitamino-calcique, son procede d'obtention et son utilisation |
GB9710521D0 (en) | 1997-05-22 | 1997-07-16 | Boots Co Plc | Process |
ITFI970184A1 (it) | 1997-07-30 | 1999-01-30 | Menarini Farma Ind | Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico |
US6232351B1 (en) * | 1998-05-22 | 2001-05-15 | Amway Corporation | Co-processed botanical plant composition |
IL126746A0 (en) * | 1998-10-26 | 1999-08-17 | Nutragal Ltd Dev Production An | Calcium salt compositions having improved solubility and method for preparing them |
DE19927537A1 (de) | 1999-06-16 | 2000-12-21 | Merck Patent Gmbh | Sprühtrocknungsanlage und Verfahren zu ihrer Verwendung |
DK1126017T3 (da) | 2000-02-18 | 2006-02-06 | Glatt Ingtech Gmbh | Fremgangsmåde til fremstilling af höjeffektive vaskemidler og komponenter i höjeffektive vaskemidler |
AR028064A1 (es) | 2000-05-03 | 2003-04-23 | Omnia Fertilizer Ltd | Metodo para producir granulos de nitrato de calcio |
JP2001316249A (ja) | 2000-05-11 | 2001-11-13 | Lion Corp | 錠剤型医薬組成物 |
US6499984B1 (en) * | 2000-05-22 | 2002-12-31 | Warner-Lambert Company | Continuous production of pharmaceutical granulation |
EP1369131A1 (en) | 2001-03-06 | 2003-12-10 | Kyowa Hakko Kogyo Co., Ltd. | Utilization of spray-dried powder containing sugar alcohol |
US20040071772A1 (en) * | 2001-03-06 | 2004-04-15 | Shoichi Narita | Preparations quickly disintegrating in oral cavity |
JP2003016785A (ja) * | 2001-06-28 | 2003-01-17 | Sharp Corp | 半導体記憶装置およびそれを用いた情報機器 |
ES2192136B1 (es) | 2002-01-04 | 2005-03-16 | Italfarmaco, S.A. | Composiciones farmaceuticas para el tratamiento o prevencion de la osteoporosis. |
DE20216314U1 (de) | 2002-10-22 | 2003-12-04 | Dhw Deutsche Hydrierwerke Gmbh Rodleben | Sprühgetrockneter Xylitol und aus diesem hergestellte Komprimate |
-
2006
- 2006-02-02 NZ NZ556465A patent/NZ556465A/en unknown
- 2006-02-02 WO PCT/IB2006/000195 patent/WO2006082501A2/en active Application Filing
- 2006-02-02 US US11/883,536 patent/US8808735B2/en not_active Expired - Fee Related
- 2006-02-02 CA CA2644400A patent/CA2644400C/en not_active Expired - Fee Related
- 2006-02-02 UA UAA200709809A patent/UA88943C2/ru unknown
- 2006-02-02 AU AU2006211023A patent/AU2006211023B2/en not_active Ceased
- 2006-02-02 EP EP06710307A patent/EP1845950A2/en not_active Withdrawn
- 2006-02-02 CN CN200680003958XA patent/CN101128186B/zh not_active Expired - Fee Related
- 2006-02-02 EA EA200701653A patent/EA013867B1/ru not_active IP Right Cessation
- 2006-02-02 CN CN201310206506.3A patent/CN103479582A/zh active Pending
- 2006-02-02 JP JP2007553728A patent/JP5305374B2/ja not_active Expired - Fee Related
-
2007
- 2007-07-18 ZA ZA2007/05875A patent/ZA200705875B/en unknown
- 2007-07-19 IL IL184714A patent/IL184714A0/en unknown
- 2007-09-03 NO NO20074480A patent/NO20074480L/no not_active Application Discontinuation
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4846409A (en) * | 1986-10-17 | 1989-07-11 | Bayer Aktiengesellschaft | Process for the preparation of granules |
EP0265951A2 (en) * | 1986-10-31 | 1988-05-04 | Rhone-Poulenc Basic Chemicals Co. | Granular tricalcium phosphate compositions suitable for direct compression tableting |
US5108728A (en) * | 1990-03-03 | 1992-04-28 | Bk Ladenburg Gmbh | Process for the production of granulated dicalcium phosphate dihydrate |
WO1996009036A1 (fr) * | 1994-09-23 | 1996-03-28 | Laboratoire Innothera, Societe Anonyme | Association therapeutique vitamino-calcique sous forme galenique unitaire de comprimes, son procede d'obtention et son utilisation |
US5883047A (en) * | 1996-04-03 | 1999-03-16 | Basf Aktiengesellschaft | Granules of hygroscopic, water-soluble products |
WO2000028973A1 (en) * | 1998-11-13 | 2000-05-25 | Nycomed Pharma As | Process for preparing oral calcium compositions |
US20050232989A1 (en) * | 1998-11-13 | 2005-10-20 | Piene Jan Y | Process for preparing oral calcium compositions |
CN101128186B (zh) * | 2005-02-03 | 2013-07-03 | 奈科明制药有限公司 | 制备含钙组合物的快速湿聚结方法 |
Also Published As
Publication number | Publication date |
---|---|
AU2006211023B2 (en) | 2012-05-24 |
JP5305374B2 (ja) | 2013-10-02 |
US20080317842A1 (en) | 2008-12-25 |
CN101128186A (zh) | 2008-02-20 |
EP1845950A2 (en) | 2007-10-24 |
CA2644400C (en) | 2014-04-08 |
NZ556465A (en) | 2010-10-29 |
CA2644400A1 (en) | 2006-08-10 |
US8808735B2 (en) | 2014-08-19 |
WO2006082501A2 (en) | 2006-08-10 |
NO20074480L (no) | 2007-11-02 |
UA88943C2 (ru) | 2009-12-10 |
AU2006211023A1 (en) | 2006-08-10 |
IL184714A0 (en) | 2007-12-03 |
JP2008528676A (ja) | 2008-07-31 |
EA013867B1 (ru) | 2010-08-30 |
WO2006082501A3 (en) | 2006-12-07 |
ZA200705875B (en) | 2012-12-27 |
EA200701653A1 (ru) | 2007-12-28 |
CN101128186B (zh) | 2013-07-03 |
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Correction item: Priority number Correct: PA2005 00168 False: 2005 00168 Number: 01 Volume: 30 |
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Correction item: Priority number Correct: PA2005 00168 False: 2005 00168 Number: 01 Page: The title page Volume: 30 |
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