CN103463199A - Composition for subcutaneous tissue trauma - Google Patents
Composition for subcutaneous tissue trauma Download PDFInfo
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- CN103463199A CN103463199A CN2012101865527A CN201210186552A CN103463199A CN 103463199 A CN103463199 A CN 103463199A CN 2012101865527 A CN2012101865527 A CN 2012101865527A CN 201210186552 A CN201210186552 A CN 201210186552A CN 103463199 A CN103463199 A CN 103463199A
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Abstract
A composition for subcutaneous tissue trauma comprises: by weight percentage, 0.3-0.4% of lotus root powder, 0.1-0.2% of an antimicrobial agent and the balance of paraffin oil. The composition for the subcutaneous tissue trauma can promote flesh granulation proliferation and forming at a traumatic part, and can help traumatic part recovery and eliminate traumatic part scars.
Description
Technical field
The present invention is about a kind of constituent, particularly a kind of constituent that contributes to the subcutaneous tissue wound healing.
Background technology
The subcutaneous tissue wound of often encountering in daily life includes: the wounds such as lacerated wound, knife injury, incised wound, scratch or burn and scald.Once produce these described wounds at subcutaneous tissue, except being cleared up, sterilized in traumatic part, general family all has traumatic usually, this traumatic is spread upon on traumatic part, to avoid traumatic part to be subject to antibacterial, infect, and this traumatic also also has the effects such as antiinflammatory or pain relieving, to alleviating the wounded's pain.
In general family, common existing traumatic comprises the Mentholatum (Mentholatum) of doctor trained in Western medicine patent medicine, and the traditional Chinese medical science patent medicine such as YUNNAN BAIYAO or Comfrey Balm.Usually these traumatics can not make the granulation hyperplasia in traumatic part, and therefore, existing traumatic is with so that, in the process of traumatic part healing, often have pigementation, or the healing surface irregularity, and stays ugly cicatrix.
The main component of Mentholatum is Herba Menthae and vaseline, curative effect is " be used for slowing down that the wind-induced nasal obstruction of wound, headache, chest are gloomy, the external cold medication of cough and skin pain ", therefore, Mentholatum is not the general cognitive wound medication of the public, can't be applied to avoid traumatic part to be subject to antibacterial infection, antiinflammatory, pain relieving etc., more can't make the traumatic part granulation hyperplasia to accelerate the healing rate in traumatic part.
Except Mentholatum, common people can arrive Chinese herbalist clinic and buy the use of traditional Chinese medical science patent medicine.For instance, common traditional Chinese medical science patent medicine for oral administration is as the Yunnan BAIYAO, and its major function is hemostasis wound healing, Repercusion analgesia, treating blood disorders blood stasis dispelling etc.; In addition, common external traditional Chinese medical science patent medicine is as Comfrey Balm, and its main component includes Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Oleum Sesami and Cera Flava, and it has the functions such as antibiotic, antiinflammatory, pain relieving.
Yet, no matter be YUNNAN BAIYAO or Comfrey Balm, the two all can do nothing to help the formation new life's in traumatic part granulation, and then promotion wound healing, make the traumatic part preventing from scar, and existing traumatic is applied on wound, the time of the required recovery of wound is longer, recovery period is longer, and the wounded's time that mouthful pain does not feel well due to wound is also longer.
Summary of the invention
Main purpose of the present invention is to provide a kind of constituent for the subcutaneous tissue wound, and this constituent can promote granulation hyperplasia and the formation in traumatic part.
Of the present invention time a purpose is to provide a kind of constituent for the subcutaneous tissue wound, can help the traumatic part Fast Restoration.
For reaching aforementioned goal of the invention, the present invention includes for the constituent of subcutaneous tissue wound:
0.3 ~ 0.4% Lotus root congee by weight percentage, 0.1 ~ 0.2% antibacterial, all the other ratios are supplied with paraffin oil.
Wherein, this antibacterial is optional from selecting the group be comprised of quadracycline and silver sulfadiazine.
The present invention separately can comprise 0.77 ~ 1.15% Antrodia camphorata powder by weight percentage for the constituent of subcutaneous tissue wound.
The accompanying drawing explanation
Fig. 1: different traumatic parts kind is applied the treatment bar chart in time of constituent of the present invention and existing medicine.
The specific embodiment
For above-mentioned and other purpose, feature and advantage of the present invention can be become apparent, preferred embodiment of the present invention cited below particularly, and coordinate accompanying drawing, be described in detail below:
Please refer to the 1st table, for the preferred embodiment of the constituent for the subcutaneous tissue wound of the present invention, the constituent for the subcutaneous tissue wound of the present invention, include 0.3 ~ 0.4% Lotus root congee by weight percentage, 0.1 ~ 0.2% antibacterial, all the other ratios are supplied with paraffin oil.
This Lotus root congee is the active ingredient that makes the traumatic part healing, according to Chinese medicines, learns and carries, and Rhizoma Nelumbinis has the effect of removing heat from blood, dissipating blood stasis, for the granulation that promotes traumatic part is newborn, with formation, has splendid effect.The Lotus root congee of the present embodiment is got dry Rhizoma Nelumbinis, and Rhizoma Nelumbinis is ground to form to Lotus root congee, this Lotus root congee is better to be ground to below 120 orders, make this Lotus root congee can evenly be applied in traumatic part, and make this Lotus root congee can be attached at more closely this traumatic part, to reach the granulation that promotes traumatic part, form and newborn effect.
This antibacterial, make traumatic part not infected by antibacterial and cause the inflammation symptom.The antibacterial of the present embodiment is preferably to be selected from selects the group be comprised of tetracycline (Tetracyclin hydrochloride) and silver sulfadiazine (Sulfadimidine).Wherein, tetracycline is a kind of wide antibiotic of using, can be in order to suppress multiple gram positive bacteria or negative bacterium growth, gram positive bacterias such as streptococcus pneumoniae, streptococcus, staphylococcus, anthrax cold bacillus or clostridium, or as the growth of the gram negative bacterias such as escherichia coli, aerobacteria, Brucella, pasteurellosis bacillus; Silver sulfadiazine is a kind of white crystalline powder, water insoluble or ethanol equal solvent, and silver sulfadiazine is except having bacteriostasis, as suppress outside Pseudomonas aeruginosa, have more astriction, can make the surface of wound accelerate drying, make traumatic part incrustation and healing fast.In addition, if the percentage by weight of this antibacterial lower than 0.1%, can't reach anti-bacteria, infect, if the percentage by weight of this antibacterial higher than 0.2%, wound easily produces the inflammation phenomenon and redness is festered.
This paraffin oil (Petrolatum) is as figuration supporting agent of the present invention, make constituent of the present invention easily be coated on traumatic part, make this Lotus root congee and this antibacterial can be fully and the traumatic part effect, and by traumatic part and isolate from outer air, avoid wound to be subject to the pollutions such as microgranule in outside air, dust, and affect the recovery situation in traumatic part.
Please refer to the 3rd embodiment of the 1st table, the present invention separately can comprise 0.77 ~ 1.15% Antrodia camphorata powder by weight percentage for the constituent of subcutaneous tissue wound, is the effect that contributes to strengthen hyperplasia, shortens the course for the treatment of of traumatic part healing.There is the compositions such as abundant sudismase (SOD), polysaccharides (β-Glucan) and three note classes (Triterpenoids) due to Antrodia camphorata, there is the effects such as immunomodulating, antioxidation.Wherein, polysaccharides is a kind of active component of accelerating wound healing, according to people such as Kougias P., in calendar year 2001 research, finds, has the polysaccharides receiver on fibroblast and can be combined with polysaccharides, and then promote wound healing; In addition, the regeneration that polysaccharides more can stimulation collagen, more contribute to wound healing to become a smooth outward appearance, reduces the generation of cicatrix.
The 1st table: the composition of preferred embodiment of the present invention and ratio thereof
For confirming that the constituent for the subcutaneous tissue wound of the present invention has granulation hyperplasia and the formation that promotes traumatic part really, make the traumatic part Fast Restoration, to shorten the wounded's uncomfortable period that mouthful pain is followed due to wound.Please refer to shown in the 2nd table, is that the kind in different traumatic parts is used the treatment time of constituent of the present invention, with and restore the description of situation.
The 2nd table: the treatment time of using constituent of the present invention in different traumatic parts kind
| Group | The traumatic part kind | Constituent A of the present invention | Existing medicine B |
| 1 | Scratch | 5 ~ 7 days | 10 ~ 16 |
| 2 | Knife injury/incised wound | 5 ~ 7 days | 10 ~ 16 |
| 3 | Burn and scald | 25 ~ 45 days | 35 days to 3 months |
1. bruised wounds: constituent of the present invention (proportion of composing of the first embodiment as shown in the 1st table) is applied on general bruised wounds, can smear at least 1 every day, it is thick that the smearing thickness of this constituent is about 0.1 ~ 0.5mm, make constituent of the present invention be covered in this wound surface fully, approximately smear to 5th ~ 7 days and restore fully, and this wound scar not.
2. knife injury or incised wound wound: constituent of the present invention (proportion of composing of the second embodiment as shown in the 1st table) is applied on the wound of general knife injury or incised wound, the degree of depth of this wound surpasses the dark person of 3mm, in the darning mode, wound is forced to closure, in this darning position, smear 1 ~ 2 time every day, it is thick that the smearing thickness of this constituent is about 0.5 ~ 1.0mm, make constituent of the present invention be covered in this bruised wounds fully, approximately smear to 7th ~ 10 days and restore fully, and this wound scar not.Yet, if be applied in scratch, knife injury or incised wound wound to have medicine now, although recovery situation and the present invention are close, yet, smear wound to have medicine now, required recovery time is longer, approximately 10 ~ 16 days.
3. burn and scald wound: constituent of the present invention (proportion of composing of the 3rd embodiment as shown in the 1st table) is applied on the wound of general burn and scald, this burn and scald wound is that two degree are burnt, smear every day 1 time, it is thick that the smearing thickness of this constituent is about 2.0 ~ 3.0mm, make constituent of the present invention be covered in this bruised wounds fully, approximately smearing to 25th ~ 45 days can restore fully, and this burn and scald wound granulation hyperplasia while restoring is all right, only stays a little cicatrix.If use existing medicine to be applied on the burn and scald wound, inhomogeneous due to granulation new life, therefore the skin of wound after more is comparatively coarse and nonelastic, in addition, the time of the existing required recovery of medicine is also longer, approximately 35 days to 3 months, it is more flexible that existing medicine can't reach Fast Restoration and this wound skin surface after more.
Please refer to shown in Fig. 1, for constituent of the present invention and existing medicament administration on the wounds such as scratch, knife injury and burn and scald, the treatment bar chart in time of this required recovery in traumatic part, wherein, A is constituent of the present invention, B is existing medicine, and X-axis is different wound kinds: (1) scratch, (2) knife injury and (3) burn and scald, Y-axis is restored required average time for various types of wound.Which kind of wound no matter constituent of the present invention be applied on, the required treatment of all existing medicine will be shortened more than 5 to 10 days time, really have more to shorten than existing medicine with this susceptible of proof constituent of the present invention and treat time, to shorten the wounded mouth and the effect in period of not feeling well due to wound.
No matter above, be the traumatic parts such as scratch, knife injury and burn and scald, after all need the dirty or dust on this wound being removed with the program of generally clearing up wound surface, after the sterilizations such as BAIYAO water, then application constituent of the present invention, to avoid wound infection or to restore in poor shape situation, occur.In addition, constituent for the subcutaneous tissue wound of the present invention, can be according to the serious situation of wound infection whether, alternative is selected the interpolation antibacterial, this antibacterial selects free ethacridine (Acrinol), sees the group that large mycin (Gentamicin) and nioform (Iodochlorhydroxyquin) form, is not subject to the effect of the infection of specific bacteria, mycete to strengthen this traumatic part.
Whereby, the constituent for the subcutaneous tissue wound of the present invention can promote granulation hyperplasia and the formation in traumatic part, has the traumatic part of help and restores, and eliminates the effect of traumatic part cicatrix.
Constituent for the subcutaneous tissue wound of the present invention can help the traumatic part Fast Restoration, has and shortens the wounded's effect of the time that mouthful pain does not feel well due to wound.
Claims (5)
1. the constituent for the subcutaneous tissue wound, it is characterized in that: this constituent comprises 0.3 ~ 0.4% Lotus root congee by weight percentage, 0.1 ~ 0.2% antibacterial, all the other ratios are supplied with paraffin oil.
2. the constituent for the subcutaneous tissue wound as claimed in claim 1, it is characterized in that: this antibacterial is selected quadracycline or silver sulfadiazine or the combination of the two.
3. the constituent for the subcutaneous tissue wound as claimed in claim 1 or 2, is characterized in that: separately comprise 0.77 ~ 1.15% Antrodia camphorata powder by weight percentage.
4. the constituent for the subcutaneous tissue wound as claimed in claim 1 or 2, it is characterized in that: separately add at least one antibacterial, this antibacterial is selected ethacridine or is seen large mycin or nioform or aforementioned three's combination in any.
5. the constituent for the subcutaneous tissue wound as claimed in claim 3, it is characterized in that: separately add at least one antibacterial, this antibacterial is selected ethacridine or is seen large mycin or nioform or aforementioned three's combination in any.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101865527A CN103463199A (en) | 2012-06-07 | 2012-06-07 | Composition for subcutaneous tissue trauma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101865527A CN103463199A (en) | 2012-06-07 | 2012-06-07 | Composition for subcutaneous tissue trauma |
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| CN103463199A true CN103463199A (en) | 2013-12-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012101865527A Pending CN103463199A (en) | 2012-06-07 | 2012-06-07 | Composition for subcutaneous tissue trauma |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000297044A (en) * | 1999-04-13 | 2000-10-24 | Sunstar Inc | Transdermal patch for external use for skin |
| CN101062054A (en) * | 2007-06-08 | 2007-10-31 | 郑淑芬 | Medicine for curing wound |
| CN101874863A (en) * | 2009-04-29 | 2010-11-03 | 朱洪河 | External plaster for dispelling scar |
| CN101897990A (en) * | 2010-07-06 | 2010-12-01 | 大连理工大学 | Dressing composition used for inhibiting scars and accelerating wound healing and application thereof |
-
2012
- 2012-06-07 CN CN2012101865527A patent/CN103463199A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000297044A (en) * | 1999-04-13 | 2000-10-24 | Sunstar Inc | Transdermal patch for external use for skin |
| CN101062054A (en) * | 2007-06-08 | 2007-10-31 | 郑淑芬 | Medicine for curing wound |
| CN101874863A (en) * | 2009-04-29 | 2010-11-03 | 朱洪河 | External plaster for dispelling scar |
| CN101897990A (en) * | 2010-07-06 | 2010-12-01 | 大连理工大学 | Dressing composition used for inhibiting scars and accelerating wound healing and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 浦跃武等: "樟芝的研究及其应用现状", 《中国医院药学杂志》 * |
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Application publication date: 20131225 |