CN103458899A - 治疗阻塞性睡眠呼吸暂停的方法 - Google Patents

治疗阻塞性睡眠呼吸暂停的方法 Download PDF

Info

Publication number
CN103458899A
CN103458899A CN2012800065522A CN201280006552A CN103458899A CN 103458899 A CN103458899 A CN 103458899A CN 2012800065522 A CN2012800065522 A CN 2012800065522A CN 201280006552 A CN201280006552 A CN 201280006552A CN 103458899 A CN103458899 A CN 103458899A
Authority
CN
China
Prior art keywords
sleep
osa
pharmaceutical composition
pyridostigmine
apnea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2012800065522A
Other languages
English (en)
Chinese (zh)
Inventor
樊建强
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFANTASTIC MEDICAL RESEARCH INSTITUTE LLC
Original Assignee
PFANTASTIC MEDICAL RESEARCH INSTITUTE LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFANTASTIC MEDICAL RESEARCH INSTITUTE LLC filed Critical PFANTASTIC MEDICAL RESEARCH INSTITUTE LLC
Priority to CN201610821591.8A priority Critical patent/CN107007602A/zh
Publication of CN103458899A publication Critical patent/CN103458899A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/56—Devices for preventing snoring
    • A61F5/566—Intra-oral devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Nursing (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2012800065522A 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法 Pending CN103458899A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610821591.8A CN107007602A (zh) 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161437272P 2011-01-28 2011-01-28
US61/437,272 2011-01-28
PCT/US2012/022825 WO2012103398A2 (en) 2011-01-28 2012-01-27 Methods for treating obstructive sleep apnea

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201610821591.8A Division CN107007602A (zh) 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法

Publications (1)

Publication Number Publication Date
CN103458899A true CN103458899A (zh) 2013-12-18

Family

ID=46577943

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2012800065522A Pending CN103458899A (zh) 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法
CN201610821591.8A Pending CN107007602A (zh) 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201610821591.8A Pending CN107007602A (zh) 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法

Country Status (6)

Country Link
US (2) US8753327B2 (https=)
EP (1) EP2672972B1 (https=)
JP (2) JP2014503593A (https=)
CN (2) CN103458899A (https=)
CA (1) CA2825309C (https=)
WO (1) WO2012103398A2 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110198688A (zh) * 2016-12-23 2019-09-03 皇家飞利浦有限公司 用于处置至少两个用户间的打鼾的系统
CN110799181A (zh) * 2017-04-28 2020-02-14 布里格姆妇女医院 用于治疗睡眠呼吸暂停的方法和组合物
CN114504643A (zh) * 2021-12-24 2022-05-17 北京大学第一医院 抗IgE抗体在用于治疗OSAS中的应用
CN117402958A (zh) * 2023-10-26 2024-01-16 天津医科大学总医院 Claudin3及家族相关分子对阻塞性睡眠呼吸暂停低通气综合征的诊断价值
US11911351B2 (en) 2018-01-30 2024-02-27 Apnimed, Inc. (Delaware) Methods for treating sleep apnea with combinations of atomoxetine and (R)-oxybutynin
US12558327B2 (en) 2019-02-08 2026-02-24 The Brigham And Women's Hospital, Inc. Methods and compositions for treating sleep apnea

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014503593A (ja) * 2011-01-28 2014-02-13 ファンタスティック・メディカル・リサーチ・インスティテュート・エルエルシー 閉塞性睡眠時無呼吸を処置するための方法
US20160361192A1 (en) * 2014-03-03 2016-12-15 Sleep Innovations Pty Ltd Device and method for sleep apnoea treatment
US10166268B2 (en) 2014-07-25 2019-01-01 The George Washington University Oxytocin improves treatment of obstructive sleep apnea
AU2016243801B2 (en) 2015-04-02 2020-05-21 Hill-Rom Services Pte. Ltd. Manifold for respiratory device
EP3824881B1 (en) * 2018-06-18 2022-02-16 Amneal Complex Products Research LLC Extended release compositions comprising pyridostigmine
CN112601568B (zh) * 2018-08-24 2024-07-26 皇家飞利浦有限公司 利用压力治疗系统提供睡眠治疗
US20200282215A1 (en) 2019-03-06 2020-09-10 Medtronic Xomed, LLC Evaluating stimulation eficacy for treating sleep apnea and lingual muscle tone sensing system for improved osa therapy
EP4620390A1 (en) * 2022-12-28 2025-09-24 Nishikawa Co., Ltd. Health risk determination system, autonomic nerve determination system, life improvement system, sleeping posture determination system, sleeping posture determination program, bruxism detection system, and bruxism detection program

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6034117A (en) * 1995-12-19 2000-03-07 A & Science Invest Ab Methods of treating and diagnosing sleep disordered breathing and means for carrying out the method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2247662B (en) 1990-08-31 1994-11-02 Instance Ltd David J Labels and manufacture thereof
US7297691B2 (en) * 2003-08-13 2007-11-20 Janssen Pharmaceutica N.V. Treatment of sleep disorders with cholinesterase inhibitors
CN101291663A (zh) * 2005-09-16 2008-10-22 赛诺科学股份公司 预防和治疗睡眠呼吸障碍的方法和工具
US20080066739A1 (en) * 2006-09-20 2008-03-20 Lemahieu Edward Methods and systems of delivering medication via inhalation
US7984714B2 (en) * 2006-09-29 2011-07-26 Nellcor Puritan Bennett Llc Managing obstructive sleep apnea and/or snoring using local time released agents
JP2014503593A (ja) * 2011-01-28 2014-02-13 ファンタスティック・メディカル・リサーチ・インスティテュート・エルエルシー 閉塞性睡眠時無呼吸を処置するための方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6034117A (en) * 1995-12-19 2000-03-07 A & Science Invest Ab Methods of treating and diagnosing sleep disordered breathing and means for carrying out the method

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110198688A (zh) * 2016-12-23 2019-09-03 皇家飞利浦有限公司 用于处置至少两个用户间的打鼾的系统
CN110799181A (zh) * 2017-04-28 2020-02-14 布里格姆妇女医院 用于治疗睡眠呼吸暂停的方法和组合物
US11911351B2 (en) 2018-01-30 2024-02-27 Apnimed, Inc. (Delaware) Methods for treating sleep apnea with combinations of atomoxetine and (R)-oxybutynin
US12558327B2 (en) 2019-02-08 2026-02-24 The Brigham And Women's Hospital, Inc. Methods and compositions for treating sleep apnea
CN114504643A (zh) * 2021-12-24 2022-05-17 北京大学第一医院 抗IgE抗体在用于治疗OSAS中的应用
CN114504643B (zh) * 2021-12-24 2024-03-26 北京大学第一医院 抗IgE抗体在用于治疗OSAS中的应用
CN117402958A (zh) * 2023-10-26 2024-01-16 天津医科大学总医院 Claudin3及家族相关分子对阻塞性睡眠呼吸暂停低通气综合征的诊断价值

Also Published As

Publication number Publication date
JP2014503593A (ja) 2014-02-13
CA2825309A1 (en) 2012-08-02
CA2825309C (en) 2019-10-01
WO2012103398A9 (en) 2012-09-27
JP2017095485A (ja) 2017-06-01
EP2672972A4 (en) 2014-09-10
WO2012103398A2 (en) 2012-08-02
EP2672972A2 (en) 2013-12-18
JP6342525B2 (ja) 2018-06-13
US8753327B2 (en) 2014-06-17
US9295670B2 (en) 2016-03-29
EP2672972B1 (en) 2020-11-04
US20120197235A1 (en) 2012-08-02
US20140238412A1 (en) 2014-08-28
CN107007602A (zh) 2017-08-04

Similar Documents

Publication Publication Date Title
US9295670B2 (en) Methods for treating obstructive sleep apnea
Gotsopoulos et al. Oral appliance therapy reduces blood pressure in obstructive sleep apnea: a randomized, controlled trial
Casey et al. Sleep-related hypoventilation/hypoxemic syndromes
CN110799181A (zh) 用于治疗睡眠呼吸暂停的方法和组合物
JP2023038310A (ja) １９－ノルｃ３，３－二置換ｃ２１－ｎ－ピラゾリルステロイドおよびその使用方法
Friedman et al. Sleep disturbances and Parkinson's disease
JP2007505139A (ja) 診断された呼吸疾患を有する患者もしくは診断未確定の呼吸疾患を有する患者におけるオピオイド鎮痛薬の投与に関連する危険性を減少するための方法および組成
CN100558358C (zh) 唑尼沙胺在制备用于治疗或预防阻塞性睡眠呼吸暂停的药物中的应用
Jyothi et al. Obstructive sleep apnea: A pathophysiology and pharmacotherapy approach
Stepanski et al. A double-blind trial of protriptyline in the treatment of sleep apnea syndrome
HK1241728A1 (en) Methods for treating obstructive sleep apnea
McNicholas Sleep in chronic obstructive pulmonary
KR20250000641A (ko) 수면장애 및/또는 수면장애 관련 질환을 예방, 개선 또는 치료하는 방법
US9622997B2 (en) Methods for treating insomnia
Krieger et al. Obstructive sleep apnea and cardiovascular disease: Implications for clinical practice
Schmickl et al. 0567 Side Effects of Acetazolamide-A Systematic Review and Meta-Analysis Assessing Overall Risk and Dose-Dependence
Catterall et al. Ketotifen and nocturnal asthma.
Dobbin et al. Obstructive sleep apnea: recognition and management considerations for the aged patient
Bashir et al. Sleep and asthma
Culebras Sleep disorders and neuromuscular disorders
Waldhorn Sleep disorders in the elderly
Jones et al. Sleep and breathing disorders in adults
Roy Medicational Effect on Sleep
Colle et al. Hypertension in Obstructive Sleep Apnoea
Gorripati et al. Pharmacological and Non-Pharmacological Management of Obstructive Sleep Apnea.(2023)

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20131218

RJ01 Rejection of invention patent application after publication