A kind of micro-whole whitening imports elite and preparation method thereof
Technical field
The present invention relates to shaping medical cosmetology product technical field, especially relate to a kind of for " micro-shaping " or " non-surgical medical beauty treatment " project, containing natural composite whitening active component, the micro-whole whitening of maintenance type specialty imports elite and preparation method thereof.
Background technology
Whitening, be an effect (energy) term of skin nursing, and its implication is: 1, desalination skin (be mainly face) melanin pigmentation, drive away obscurely, and make it present pale, bright appearance; 2, dispel or desalinate mottle, as freckle, chloasma, person in middle and old age's speckle, acne speckle, melanoma etc., eliminating flaw, beautifying face.Certainly, whitening is a main flow consumption demand in cosmetics market.The method of tradition skin whitening, be mainly by using skin-lightening cosmetic, relies on nursing means in beauty parlor's to realize.Yet, along with the progress of shaping medical cosmetology technology, " micro-shaping " whitening extensively adopts in all kinds of professional medical science (treatment) cosmetic surgery hospital, become the important means that solves the skin-whitening problem.So-called " micro-shaping ", adopt the professional medical beauty treatment instruments such as laser, radio frequency, electric U.S.A mould, glory, micropin exactly, and the collocation product reaches the method for beauty treatment, as " the light speckle of photon ", " micropin whitening " etc.It is different from surgery " operation " shaping, does not relate to " moving knife " on macroscopic view, also can not cause the obvious wound of skin.So " micro-shaping " is otherwise known as " non-surgical medical beauty treatment ", it has the vertical advantage such as existing of short, effect of noinvasive or Wicresoft, convalescent period.Market development shows, " micro-shaping " occupied the share of shaping medical and beauty treatment 80%, becomes the fastest-rising project of medical cosmetology, and the personage that is subject to liking to be beautiful constantly pursues.
" micro-shaping " whitening will obtain desirable effect, and an importance is and the matching used product of " micro-shaping " apparatus.Prior art, " micro-shaping " whitening product used in cosmetic surgery hospital is mainly that the biochemical composites of folk prescription stock solution type such as NAP (vitamin C derivatives), tranamic acid (Trenaxmine), Chinese mugwort ground benzene (coenzyme Q10 derivant), glabridin (licoflavone) are in the majority, composition is single, fiting effect is limited, all only for melanin " target spot " effect, (activity of restraint of tyrosinase reduces melanic generation, or the melanin generated is decomposed, reduces), persistency is poor, easily regeneration.The most obvious defect is: the whitening function principle of not complete consideration " micro-shaping " apparatus, as, " Wicresoft " skin injury is arranged, need maintenance (as antiinflammatory, take off red, dispeling scar etc.) and effect consolidate (as moisturizing, nutritional supplementation, the barrier reparation, deep layer is dispelled black, cell activation, prevent regeneration etc.).In fact, result according to modern Dermatology research, the mechanism that melanin forms is simple like this more than only suppressing " tryrosinase activation ", also with age, sex, and skin impaired (inflammation), toxin (oxygen-derived free radicals), immunity, emotion etc. are multifactor relevant, therefore, desirable " micro-shaping " whitening product also should be considered " multifactor whitening mechanism " such as the reparations, activation, consolidation (immunity) of skin, to obtain lasting, satisfactory collocation result of use.
Summary of the invention
Purpose of the present invention is exactly the defect existed in order to overcome above-mentioned prior art, according to whitening function principle, using method (program) and the course for the treatment of of " micro-shaping " apparatus, and according to modern times reparation, activation, consolidation (immunity) " multifactor whitening mechanism ", science is screened natural composite whitening active component, provides a kind of safe, the micro-shaping instrumentation of specialty collocation, micro-whole whitening of maintenance type to import elite and preparation method thereof.
To achieve these goals, the present invention adopts following technical scheme:
A kind of micro-whole whitening imports elite, it is characterized in that, its component by following percentage by weight forms: nasturtium extract 4.0%~6.0%; Brown alga extract 3.0%~6.0%; Fructus Phyllanthi extract 0.1%~1.0%; Turmeric extract 0.05%~0.2%; Radix Scutellariae root extract 2.0%~4.0%; Hydrolysis zein 0.5%~1.5%; Hydrolysed rice albumen 0.5%~1.5%; Yeast beta-dextran 5.0%~10.0%; The smooth olive oil acid esters 0.2%~0.5% of cetearyl alcohol olive oil acid esters and/or Pyrusussuriensis; Glyceryl stearate citrate propylene glycol 0.5%~1.5%; Propylene glycol 3.0%~5.0%; 1,2 one pentanediol 3.0%~5.0%; Flos Magnoliae glycol 1.0%~3.0%; Garcinia indica seed oil 2.0%~4.0%; Tocopherol acetas 0.5%~1.5%; NAP 1.0%~3.0%; EDETATE SODIUM 0.05%~0.1%; Natto gum 0.2%~1.0%; Citric acid 0.03%~0.07%; Surplus is deionized water.
As the present invention, preferably, micro-whole whitening importing elite is comprised of the component of following percentage by weight: nasturtium extract 4.0%; Brown alga extract 4.0%; Fructus Phyllanthi extract 0.5%; Turmeric extract 0.1%; Radix Scutellariae root extract 3.0%; Hydrolysis zein 1.0%; Hydrolysed rice albumen 1.5%; Yeast beta-dextran 7.0%; The smooth olive oil acid esters 0.3% of cetearyl alcohol olive oil acid esters and/or Pyrusussuriensis; Glyceryl stearate citrate propylene glycol 0.5%%; Propylene glycol 4.0%; 1,2 one pentanediol 3.0%; Flos Magnoliae glycol 1.0%; Garcinia indica seed oil 2.0%; Tocopherol acetas 0.5%; NAP 2.0%; EDETATE SODIUM 0.05%; Natto gum 0.2%; Citric acid 0.05%; Surplus is deionized water.
As the present invention, preferably, micro-whole whitening importing elite is comprised of the component of following percentage by weight: nasturtium extract 5.0%; Brown alga extract 6.0%; Fructus Phyllanthi extract 0.1%; Turmeric extract 0.2%; Radix Scutellariae root extract 4.0%; Hydrolysis zein 1.5%; Hydrolysed rice albumen 0.5%; Yeast beta-dextran 5.0%; The smooth olive oil acid esters 0.2% of cetearyl alcohol olive oil acid esters and/or Pyrusussuriensis; Glyceryl stearate citrate propylene glycol 1.5%; Propylene glycol 3.0%; 1,2 one pentanediol 5.0%; Flos Magnoliae glycol 2.0%; Garcinia indica seed oil 3.0%; Tocopherol acetas 1.0%; NAP 3.0%; EDETATE SODIUM 0.08%; Natto gum 1.0%; Citric acid 0.07%; Surplus is deionized water.
As the present invention, preferably, micro-whole whitening importing elite is comprised of the component of following percentage by weight: nasturtium extract 6.0%; Brown alga extract 3.0%; Fructus Phyllanthi extract 1.0%; Turmeric extract 0.05%; Radix Scutellariae root extract 2.0%; Hydrolysis zein 0.5%; Hydrolysed rice albumen 1.0%; Yeast beta-dextran 10.0%; The smooth olive oil acid esters 0.5% of cetearyl alcohol olive oil acid esters and/or Pyrusussuriensis; Glyceryl stearate citrate propylene glycol 1.0%; Propylene glycol 5.0%; 1,2 one pentanediol 4.0%; Flos Magnoliae glycol 3.0%; Garcinia indica seed oil 4.0%; Tocopherol acetas 1.5%; NAP 1.0%; EDETATE SODIUM 0.1%; Natto gum 0.5%; Citric acid 0.03%; Surplus is deionized water.
Nasturtium extract in the present invention, extracted by the nasturtium petal, is rich in polyphenol (p-coumaric acid), can significantly be suppressed at the activity of the tryrosinase played a crucial role in the melanin forming process, reduces melanic generation.Play check melanin and generate, prevent mottle, even fair-complexioned effect.
Brown alga extract in the present invention, belong to Brown algae by the ocean tooth and extract, and is rich in hormone (pheromones) pheromone, can effectively suppress three committed steps of dermal melanin calmness: 1. control the size of immaturity melanosome and synthesize; 2. suppress the maturing of melanosome; 3. suppress ripe melanosome and move to skin surface.Rise and reduce melanin pigmentation, the effect of desalination mottle.
Fructus Phyllanthi extract in the present invention; by Fructus Phyllanthi, really extracted; the main tannic acid material containing the micromolecule amount; these materials are proved to be and can be subject to ultraviolet and oxidative damage by fine protection skin cell epimatrix (ECM) albumen; thereby can significantly reduce because of Exposure to Sunlight, electromagnetic radiation induced pigmentation, play a part to repair RADI, desalinate obstinate speckle (as freckle).
Turmeric extract in the present invention, extracted by the cassumunar xanthorrhiza, containing the high-purity tetrahydrocurcumin, has the powerful oxygen-derived free radicals of removing, and the blocking-up inflammatory process, repair the functions such as extraneous damage.Play the antioxidant pigment calmness, fast the effect of brilliant white.
Radix Scutellariae root extract in the present invention, containing biological active substanceies such as baicalin, Radix Scutellariae elements.Studies have shown that, the melanic generation of skin not only ultraviolet, oxidative damage is relevant, also closely related with environmental pollution (vehicle exhaust, industrial waste gas, tobacco smoke etc.), mental pressure (overwork, inter personal contact etc.), be also to cause dim heavy, the major reason that plays speckle of skin.The Radix Scutellariae root extract has the injury effect of good anti-environmental pollution to skin, plays the antipollution whitening function.
Hydrolysis zein in the present invention, hydrolysed rice albumen, the active polypeptide extracted by Semen Maydis and rice, the test confirmation, the skin problem that various factors is caused (color is heavy, Huang is mute, dry, irritated etc.) there is good maintenance function, play the maintenance whitening function.
Yeast beta-dextran in the present invention, produced through fermentation by Herba bromi japonici or Agaricus campestris extract.To the skin damage, especially inflammation damnification (wound, redness, cicatrix etc.) has fine repairing effect, plays antiinflammatory, removes the scar whitening function.
The smooth olive oil acid esters of cetearyl alcohol olive oil acid esters in the present invention and/or Pyrusussuriensis is naturally occurring emulsifying agent.
Glyceryl stearate citrate in the present invention is natural co-emulsifier.
In the present invention 1,2 pentanediol, Flos Magnoliae glycol are wetting agent, have bacteria resistance function concurrently, play the antiseptic effect, realize " without adding " formula.
The oils and fats that Garcinia indica seed oil in the present invention is extracted by the seed of India ancient plant Resina garciniae, have the magical effects such as moist, moisturizing, antiinflammatory, the scar of dispelling, and works to repair epidermis injury (as cicatrix), enhancing skin barrier.
Tocopherol acetas in the present invention, i.e. vitamin E, the effect of tool antioxidation, stable prod activity.
NAP in the present invention, vitamin C derivatives, be tyrosinase inhibitor, composite with each plant extract of the present invention, tool whitening potentiation has anti-senescence function (exciting skin collagen regeneration) concurrently simultaneously.
Natto gum in the present invention, have another name called natto gum.By natto, extracted, main component is poly-gamma-glutamic acid sodium, and the high moisture-keeping function of tool is collaborative with other compositions, plays the repair of epidermis injury barrier.
EDETATE SODIUM in the present invention, for metal ion chelation agents such as calcium, magnesium, ferrum, prevent that it from affecting the food ingredient activity.
Citric acid in the present invention is product acidity (pH value) regulator, regulates pH value and skin and approaches (5.0-6.5), and guarantee that Product Activity is stable.
Prepare the method that micro-whole whitening imports elite, comprise the steps:
(1) weigh deionized water in the water pot, add successively the more measured propylene glycol of accurate scale, natto gum, and be heated to while stirring 60 ℃, insulated and stirred to natto gum is uniformly dissolved, add successively 1 again, the smooth olive oil acid esters of 2-pentanediol, Flos Magnoliae glycol, cetearyl alcohol olive oil acid esters and/or Pyrusussuriensis, Glyceryl stearate citrate propylene glycol, Garcinia indica seed oil, EDETATE SODIUM, Fructus Phyllanthi extract, turmeric extract, fully be uniformly mixed, be cooled to afterwards temperature 50 C;
(2) by water pot material suction vacuum emulsifying pot, keep temperature 50 C, start the homogenizing stirring and beat homogenizing 3~5 minutes, add successively the measured nasturtium extract of accurate scale, brown alga extract, Radix Scutellariae root extract, tocopherol acetas, NAP under stirring afterwards, stir 30 minutes and beat homogenizing 3-5 minute, fully mix homogeneously;
(3) cool, when temperature drops to 40 ℃, add successively hydrolysis zein, hydrolysed rice albumen, yeast beta-dextran, and stir;
(4) continue coolingly, when temperature drops to 35 ℃, add citric acid, and stir;
(5) cooling again, when temperature drops to 30 ℃, stop stirring, sample and be cooled to the external sight of room temperature observation material, denseness, color and luster, abnormal smells from the patient, pH value, qualified is that discharging is to the semi-finished product container;
(6) semi-finished product are standing 24 hours, and semi-finished product physicochemical and microbial index check is done in sampling, qualifiedly get final product fill, pack to obtain finished product;
(7) the full index test of finished product, qualified can the warehouse-in in storage are done in sampling.
The present invention has following beneficial effect: the present invention has taken into full account whitening function principle, using method (program) and the course for the treatment of of " micro-shaping " apparatus, and according to modern " multifactor whitening mechanism ", science has been screened above natural composite whitening active component, thereby realize " micro-shaping " nourishing before the course for the treatment of, conditioning, whitening, repair, activate, consolidate science, the special and professional care of (immunity) after the course for the treatment of.
The accompanying drawing explanation
Fig. 1 is preparation technology's flow chart that micro-whole whitening imports elite.
The specific embodiment
For technological means, creation characteristic that the present invention is realized, reach purpose and effect is easy to understand, below in conjunction with concrete diagram, further set forth the present invention.
Embodiment 1: micro-whole whitening imports elite, and its component by following percentage by weight forms: nasturtium extract 4.0%; Brown alga extract 4.0%; Fructus Phyllanthi extract 0.5%; Turmeric extract 0.1%; Radix Scutellariae root extract 3.0%; Hydrolysis zein 1.0%; Hydrolysed rice albumen 1.5%; Yeast beta-dextran 7.0%; The smooth olive oil acid esters 0.3% of cetearyl alcohol olive oil acid esters and Pyrusussuriensis; Glyceryl stearate citrate propylene glycol 0.5%%; Propylene glycol 4.0%; 1,2 one pentanediol 3.0%; Flos Magnoliae glycol 1.0%; Garcinia indica seed oil 2.0%; Tocopherol acetas 0.5%; . NAP 2.0%; EDETATE SODIUM 0.05%; Natto gum 0.2%; Citric acid 0.05%; Deionized water 66.30%.The percentage by weight sum of above each component is 100%.
Referring to Fig. 1, prepare the method that micro-whole whitening imports elite, comprise the steps: that (1) weighs deionized water in the water pot, add successively the more measured propylene glycol of accurate scale, natto gum, and be heated to while stirring 60 ℃, insulated and stirred to natto gum is uniformly dissolved, add successively 1 again, the 2-pentanediol, the Flos Magnoliae glycol, the smooth olive oil acid esters of cetearyl alcohol olive oil acid esters and Pyrusussuriensis, the Glyceryl stearate citrate propylene glycol, Garcinia indica seed oil, EDETATE SODIUM, Fructus Phyllanthi extract, the turmeric extract, fully be uniformly mixed, be cooled to afterwards temperature 50 C.
(2) by water pot material suction vacuum emulsifying pot, keep temperature 50 C, start the homogenizing stirring and beat homogenizing 3 minutes, add successively the measured nasturtium extract of accurate scale, brown alga extract, Radix Scutellariae root extract, tocopherol acetas (vitamin E), NAP under stirring afterwards, stir 30 minutes and beat homogenizing 3 minutes, fully mix homogeneously.
(3) cool, when temperature drops to 40 ℃, add successively hydrolysis zein, hydrolysed rice albumen, yeast beta-dextran, and stir.
(4) continue coolingly, when temperature drops to 35 ℃, add citric acid, and stir.
(5) cooling again, when temperature drops to 30 ℃, stop stirring, sample and be cooled to the external sight of room temperature observation material, denseness, color and luster, abnormal smells from the patient, pH value, qualified is that discharging is to the semi-finished product container.These parameters can be with reference to corresponding national touchstone, such as following national touchstone, standard No.: QB/T2286-1997.
(6) semi-finished product are standing 24 hours, and semi-finished product physicochemical and microbial index check is done in sampling, qualifiedly get final product fill, pack to obtain finished product.
(7) the full index test of finished product, qualified can the warehouse-in in storage are done in sampling.
Embodiment 2: micro-whole whitening imports elite, and its component by following percentage by weight forms: nasturtium extract 5.0%; Brown alga extract 6.0%; Fructus Phyllanthi extract 0.1%; Turmeric extract 0.2%; Radix Scutellariae root extract 4.0%; Hydrolysis zein 1.5%; Hydrolysed rice albumen 0.5%; Yeast beta-dextran 5.0%; The smooth olive oil acid esters 0.2% of cetearyl alcohol olive oil acid esters and/or Pyrusussuriensis; Glyceryl stearate citrate propylene glycol 1.5%; Propylene glycol 3.0%; 1,2 one pentanediol 5.0%; Flos Magnoliae glycol 2.0%; Garcinia indica seed oil 3.0%; Tocopherol acetas 1.0%; NAP 3.0%; EDETATE SODIUM 0.08%; Natto gum 1.0%; Citric acid 0.07%; Deionized water 57.85%.The percentage by weight sum of above each component is 100%.
Referring to Fig. 1, prepare the method that micro-whole whitening imports elite, comprise the steps: that (1) weighs deionized water in the water pot, add successively the more measured propylene glycol of accurate scale, natto gum, and be heated to while stirring 60 ℃, insulated and stirred to natto gum is uniformly dissolved, add successively 1 again, the 2-pentanediol, the Flos Magnoliae glycol, the smooth olive oil acid esters of cetearyl alcohol olive oil acid esters and/or Pyrusussuriensis, the Glyceryl stearate citrate propylene glycol, Garcinia indica seed oil, EDETATE SODIUM, Fructus Phyllanthi extract, the turmeric extract, fully be uniformly mixed, be cooled to afterwards temperature 50 C.
(2) by water pot material suction vacuum emulsifying pot, keep temperature 50 C, start the homogenizing stirring and beat homogenizing 4 minutes, add successively the measured nasturtium extract of accurate scale, brown alga extract, Radix Scutellariae root extract, tocopherol acetas (vitamin E), NAP under stirring afterwards, stir 30 minutes and beat homogenizing 4 minutes, fully mix homogeneously.
(3) cool, when temperature drops to 40 ℃, add successively hydrolysis zein, hydrolysed rice albumen, yeast beta-dextran, and stir;
(4) continue coolingly, when temperature drops to 35 ℃, add citric acid, and stir.
(5) cooling again, when temperature drops to 30 ℃, stop stirring, sample and be cooled to the external sight of room temperature observation material, denseness, color and luster, abnormal smells from the patient, pH value, qualified is that discharging is to the semi-finished product container.
(6) semi-finished product are standing 24 hours, and semi-finished product physicochemical and microbial index check is done in sampling, qualifiedly get final product fill, pack to obtain finished product.
(7) the full index test of finished product, qualified can the warehouse-in in storage are done in sampling.
Embodiment 3: micro-whole whitening imports elite, and its component by following percentage by weight forms: nasturtium extract 6.0%; Brown alga extract 3.0%; Fructus Phyllanthi extract 1.0%; Turmeric extract 0.05%; Radix Scutellariae root extract 2.0%; Hydrolysis zein 0.5%; Hydrolysed rice albumen 1.0%; Yeast beta-dextran 10.0%; The smooth olive oil acid esters 0.5% of cetearyl alcohol olive oil acid esters and Pyrusussuriensis; Glyceryl stearate citrate propylene glycol 1.0%; Propylene glycol 5.0%; 1,2 one pentanediol 4.0%; Flos Magnoliae glycol 3.0%; Garcinia indica seed oil 4.0%; Tocopherol acetas 1.5%; NAP 1.0%; EDETATE SODIUM 0.1%; Natto gum 0.5%; Citric acid 0.03%; Deionized water 55.82%.The percentage by weight sum of above each component is 100%.
Referring to Fig. 1, prepare the method that micro-whole whitening imports elite, comprise the steps: that (1) weighs deionized water in the water pot, add successively the more measured propylene glycol of accurate scale, natto gum, and be heated to while stirring 60 ℃, insulated and stirred to natto gum is uniformly dissolved, add successively 1 again, the 2-pentanediol, the Flos Magnoliae glycol, the smooth olive oil acid esters of cetearyl alcohol olive oil acid esters and/or Pyrusussuriensis, the Glyceryl stearate citrate propylene glycol, Garcinia indica seed oil, EDETATE SODIUM, Fructus Phyllanthi extract, the turmeric extract, fully be uniformly mixed, be cooled to afterwards temperature 50 C.
(2) by water pot material suction vacuum emulsifying pot, keep temperature 50 C, start the homogenizing stirring and beat homogenizing 5 minutes, add successively the measured nasturtium extract of accurate scale, brown alga extract, Radix Scutellariae root extract, tocopherol acetas (vitamin E), NAP under stirring afterwards, stir 30 minutes and beat homogenizing 5 minutes, fully mix homogeneously.
(3) cool, when temperature drops to 40 ℃, add successively hydrolysis zein, hydrolysed rice albumen, yeast beta-dextran, and stir.
(4) continue coolingly, when temperature drops to 35 ℃, add citric acid, and stir.
(5) cooling again, when temperature drops to 30 ℃, stop stirring, sample and be cooled to the external sight of room temperature observation material, denseness, color and luster, abnormal smells from the patient, pH value, qualified is that discharging is to the semi-finished product container.
(6) semi-finished product are standing 24 hours, and semi-finished product physicochemical and microbial index check is done in sampling, qualifiedly get final product fill, pack to obtain finished product.
(7) the full index test of finished product, qualified can the warehouse-in in storage are done in sampling.
The foregoing is only the preferred embodiment of the present invention, protection scope of the present invention is not limited in above-mentioned embodiment, and every technical scheme that belongs to the principle of the invention all belongs to protection scope of the present invention.For a person skilled in the art, some improvement of carrying out under the prerequisite that does not break away from principle of the present invention, these improvement also should be considered as protection scope of the present invention.