CN103432393B - 一种治疗高血压的中药组合物 - Google Patents
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Abstract
本发明涉及一种治疗高血压的中药组合物,是由以下重量份的原料药制成的:何首乌12-18份,白芍10-15份,当归8-12份,川穹4-6份,炒杜仲15-20份,黄芪25-35份,黄柏4-8份,钩藤25-35份,黄精18-25份,夏枯草12-20份,益母草12-18份,车前草12-18份,豨莶草12-18份,菊花12-18份,黄芩12-18份,葛根15-30份。其安全可靠、标本兼治、疗效显著,有效率高达95%,治愈率高达80%。
Description
技术领域
本发明涉及一种中药组合物,具体涉及一种治疗高血压的中药组合物。
背景技术
随着人们经济水平提高,生活水平也得到很大的改善,但是盐份和脂肪摄入过高,过量饮酒等这些不良饮食习惯和作息不健康、生活压力大也导致了患高血压的人群日益增多。血压增高的实质,是由器官供血不足而造成的,中医诊断认为本病与肝、脾、肾有关,其发病机理为肝的气血失和、脾的升降失司、肾的阴阳失调。就一般情况而言,高血压的初期大多始于肝,进而影响脾,最后归结于肾,形成肾阴不足,肝阳上亢的高血压病。本病的表象为头痛、眩晕、耳鸣、心悸、失眠,其本质实为阴血亏虚。在现有的应用中,未能发现有较好治疗或减缓此类症状的药物,一般的降压西药用时则降,停药则升,会让患者产生极大的依赖性,仅能治标,不能治本,同时也带来了巨大的副作用,现有的技术中,也有不少的治疗高血压的中药组合物,但实践表明,这些中药组合物存在疗效一般、治疗周期长、费用高昂等缺点,广大患者急切希望能有一种治疗效果更好并且价格低廉的治疗药物。
发明内容
基于上述原因,本发明提供了一种安全可靠,标本兼治,疗效显著的治疗高血压的中药组合物,其有效率高达95%,治愈率高达80%,治疗周期短,并且价格低廉,适合广大老百姓使用。
本发明是通过以下技术方案实现的:
一种治疗高血压的中药组合物,是由以下重量份的原料药制成的:何首乌12-18份,白芍10-15份,当归8-12份,川穹4-6份,炒杜仲15-20份,黄芪25-35份,黄柏4-8份,钩藤25-35份,黄精18-25份,夏枯草12-20份,益母草12-18份,车前草12-18份,豨莶草12-18份,菊花12-18份,黄芩12-18份,葛根15-30份。
优选地,是由以下重量份的原料药制成的:何首乌15份,白芍12份,当归9份,川穹5份,炒杜仲18份,黄芪30份,黄柏6份,钩藤30份,黄精20份,夏枯草15份,益母草15份,车前草15份,豨莶草15份,菊花15份,黄芩15份,葛根20份。
优选地,是由以下重量份的原料药制成的:何首乌12份,白芍10份,当归8份,川穹4份,炒杜仲15份,黄芪25份,黄柏4份,钩藤25份,黄精18份,夏枯草12份,益母草12份,车前草12份,豨莶草12份,菊花12份,黄芩12份,葛根15份。
优选地,是由以下重量份的原料药制成的:何首乌18份,白芍15份,当归12份,川穹6份,炒杜仲20份,黄芪35份,黄柏8份,钩藤35份,黄精25份,夏枯草20份,益母草18份,车前草18份,豨莶草18份,菊花18份,黄芩18份,葛根30份。
治疗时,称取配方中的原料药,加适量温水浸泡1个小时,煎两次。首次文火煎煮10-15分钟,第二次文火煎煮30-50分钟,煎好后将两煎混合,总量约250-300毫升,每日1剂,每剂分2-3次服用,饭后2小时左右温服。
本发明的中药经数百位患者使用后,达到了良好的效果,受到患者的好评,有效率和治愈率均高于现有的中药,因此值得推广使用。
本发明的中药制剂所采用的原料药的药理药效如下:
何首乌:味苦甘涩,微温,归肝、脾经。补肝肾,益精血,乌须发,强筋骨。用于促进造血功能,提高机体免疫功能,降血脂,抗动脉粥样硬化,保肝,延缓衰老,影响内分泌功能,润肠通便。
白芍:味苦酸,微寒,归肝、脾经。补血柔肝、平肝止痛,敛阴收汗。用于抗菌、解热、抗炎、增加冠状动脉流量、改善心肌营养血流、扩张血管、降低血压、对抗急性心肌缺血、抑制血小板聚集、镇静、镇痛、解痉、抗溃疡、调节血糖。
当归:性温,味甘、辛。归肝、心、脾经。用于补血活血,调经止痛,润肠通便。用于血虚萎黄、眩晕心悸、月经不调、经闭痛经、虚寒腹痛、肠燥便秘、风湿痹痛、跌扑损伤、痈疽疮疡。
川穹:性温,味辛,归肝、胆、心包经。活血行气,祛风止痛。用于月经不调,经闭痛经,症瘕腹痛,胸胁刺痛,跌扑肿痛,头痛,风湿痹痛。
杜仲:性温,味甘。补肝肾,强筋骨,清除体内垃圾,加强人体细胞物质代谢,防止肌肉骨骼老化,平衡人体血压,分解体内胆固醇,降低体内脂肪,恢复血管弹性,利尿清热,广谱抗菌,兴奋中枢神经,提高白血球数量,增强人体免疫力。用于高血压、腰脊酸疼,足膝痿弱,小便余沥,阴下湿痒,胎漏欲堕,胎动不安。一般使用时,把杜仲炒制入药。
黄芪:味甘,性微温,归肝、脾、肺、肾经。补气固表、敛汗固脱、托疮生肌、利水消肿。用于降低血液粘稠度、减少血栓形成、降低血压、保护心脏、双向调节血糖、抗自由基损伤、抗衰老、抗缺氧、抗肿瘤、增强机体免疫力、扩张血管,改善皮肤血液循环和营养状况、消除肾炎患者的蛋白尿、保护肝脏、防止肝糖原减少、提高肺与呼吸系统免疫能力。
黄柏:味苦,寒。归肾、膀胱、大肠经。清热燥湿,泻火解毒。用于降压、止咳、抗菌、抗炎、湿热泻痢,黄疸,带下,热淋,脚气,痿辟,骨蒸劳热,盗汗,遗精,疮疡肿毒,湿疹瘙痒。
钩藤:味甘、微苦,性微寒;归肝、心包经。清热平肝,熄风止痉。主治肝火上逆头痛目赤,肝阳上亢头晕目眩,热盛动风惊痫,小儿惊风,夜啼,子痫,中风瘫痪,肢节挛急,高血压。
黄精:味甘,性平,归脾、肺、肾经。补气养阴,健脾,润肺,益肾。用于降血压、降血糖、降血脂、防止动脉粥样硬化、延缓衰老和抗菌、补脾阴、益脾气及消渴。
夏枯草:性寒,味甘、辛、微苦,归肝、胆经。清泄肝火、散结消肿、清热解毒、祛痰止咳、凉血止血。用于淋巴结核、甲状腺肿、乳痈、头目眩晕、口眼歪斜、筋骨疼痛、肺结核、血崩、带下、急性传染性黄疸型肝炎、细菌性痢疾及抵制癌细胞等。同时用于降低血压,扩张血管,其所含芦丁有抗炎作用,能降低血管通透性,减少脆性,降低肝脂。
益母草:味辛、苦、性微寒,归心、肝、膀胱经。用于活血,祛瘀,调经,消水。治月经不调,胎漏难产,胞衣不下,产后血晕,瘀血腹痛,崩中漏下,尿血,泻血,痈肿疮疡。
车前草:味甘、淡、性微寒,归肺经;肝经;肾经;膀胱经。清热利尿、渗湿止泻、明目、祛痰。用于治疗主小便不利、淋浊带下、水肿胀满、暑湿泻痢、目赤障翳、痰热咳喘、高血压。
豨莶草:味辛、苦,性寒,归肝、肾经。祛风湿,强筋骨。用于风湿关节炎、筋骨无力、腰膝酸软、四肢麻痹、半身不遂、风疹湿疮、降压和血管舒张、抗炎抗菌和抗疟。
菊花:菊花含有水苏碱、刺槐甙、木樨草甙、大波斯菊甙、腺膘呤、胆碱、葡萄糖甙等成分,尤其富含挥发油,并且油中主要为菊酮、龙脑、龙脑已酸酯等物质。功效作用方面,菊花具有平肝明目、散风清热、消咳止痛的功效,用于治疗头痛眩晕、目赤肿痛、风热感冒、咳嗽等病症效果显著。
黄芩:苦,寒。归肺、胆、脾、胃、大肠、小肠经,清热燥湿,泻火解毒,止血,安胎,降血压。用于湿温、暑温胸闷呕恶,湿热痞满,泻痢,黄疸,肺热咳嗽,高热烦渴,血热吐衄,痈肿疮毒,胎动不安。
葛根:含多种黄酮类成分,主要活性成分为大豆素、大豆甙、葛根素、葛根素-7-木糖甙等。最新资料表明,葛根具有α受体和血管紧张素Ⅱ受体亦有阻断作用,疗效优于以往各类抗高血压药物。尤其可能逆转高血压所致的心肌肥厚。葛根素可使明显增高的血浆内皮素(ET)水平较快恢复正常,故葛根素治疗高血压病的机制之一可能在于能抑制ET过量释放,促进内皮恢复功能,进而兴奋PG12合成酶活性,显著增高EC生成PG抑制血小板聚集,起到改善血液循环的作用。大剂量葛根素能降低血糖,能明显降低血清胆固醇。
具体实施方式
下面结合实施例和临床资料对本发明作进一步的说明:
实施例1:制备一种治疗高血压的中药制剂。
配方为:何首乌15份,白芍12份,当归9份,川穹5份,炒杜仲18份,黄芪30份,黄柏6份,钩藤30份,黄精20份,夏枯草15份,益母草15份,车前草15份,豨莶草15份,菊花15份,黄芩15份,葛根20份。
治疗时,按1g/份的重量称取配方中的原料药,加适量温水浸泡1个小时,煎两次。首次文火煎煮10-15分钟,第二次文火煎煮30-50分钟,煎好后将两煎混合,总量约250-300毫升,每日1剂,每剂分2-3次服用,饭后2小时左右温服。
实施例2:制备一种治疗高血压的中药制剂。
配方为:何首乌12份,白芍10份,当归8份,川穹4份,炒杜仲15份,黄芪25份,黄柏4份,钩藤25份,黄精18份,夏枯草12份,益母草12份,车前草12份,豨莶草12份,菊花12份,黄芩12份,葛根15份。
治疗时,按1g/份的重量称取配方中的原料药,加适量温水浸泡1个小时,煎两次。首次文火煎煮10-15分钟,第二次文火煎煮30-50分钟,煎好后将两煎混合,总量约250-300毫升,每日1剂,每剂分2-3次服用,饭后2小时左右温服。
实施例3:制备一种治疗高血压的中药制剂。
配方为:何首乌18份,白芍15份,当归12份,川穹6份,炒杜仲20份,黄芪35份,黄柏8份,钩藤35份,黄精25份,夏枯草20份,益母草18份,车前草18份,豨莶草18份,菊花18份,黄芩18份,葛根30份。
治疗时,按1g/份的重量称取配方中的原料药,加适量温水浸泡1个小时,煎两次。首次文火煎煮10-15分钟,第二次文火煎煮30-50分钟,煎好后将两煎混合,总量约250-300毫升,每日1剂,每剂分2-3次服用,饭后2小时左右温服。
临床资料:
病例1:李某,女,54岁,某大学教授,在52岁时常常出现头痛头晕、眩晕、耳鸣、心悸、失眠等症状,医院确诊为患有中度高血压,血压为:收缩压170,舒张压106。随后开始吃降压西药,但用时则降,停药则升,且带来了一系列心率增快、心动过速、头痛、低血压、倦怠无力、食欲不振、胃肠充气、四肢麻木等不良反应。后开始寻求中医治疗,服用本发明的中药制剂,每日1剂,每剂分2-3次服用,两周后症状得到缓解,治疗30天后各种症状消失,血压回归为正常值:收缩压130~舒张压80,至今无复发。
病例2:张某某,男,38岁,某外企主管,由于工作压力大,经常饮酒且作息不规律,在37岁时产生了头晕、心悸、失眠、神志不宁,心烦急躁等症状,后被诊断为高血压,血压为收缩压160~舒张压98。经朋友推荐,直接寻求中医治疗,2012年1月20日求助本发明人,服用本发明的中药制剂,每日1剂,每剂分2-3次服用,两周后症状明显好转,治疗30天后各种症状消失,血压下降到正常值:收缩压120~舒张压78,随访1年无复发。
病例3:高某某,男,46岁,司机,由于过度劳累且身体肥胖,44岁体检时发现患有高血压,血压为收缩压175~舒张压102,医生建议用中药调理,后开始服用本发明的中药制剂,每日1剂,每剂分2-3次服用,连续服用30天后,血压恢复到正常值:收缩压128~舒张压82,至今一直稳定无回升。
Claims (1)
1.一种治疗高血压的中药组合物,其特征在于,是由以下重量份的原料药制成的:何首乌12份,白芍10份,当归8份,川穹4份,炒杜仲15份,黄芪25份,黄柏4份,钩藤25份,黄精18份,夏枯草12份,益母草12份,车前草12份,豨莶草12份,菊花12份,黄芩12份,葛根15份;按1g/份的重量称取配方中的原料药,加适量温水浸泡1个小时,煎两次;首次文火煎煮10-15分钟,第二次文火煎煮30-50分钟,煎好后将两煎混合,总量250-300毫升。
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