CN103431411A - Milk calcium orally fast dissolving tablet convenient to be taken by infants and production method thereof - Google Patents
Milk calcium orally fast dissolving tablet convenient to be taken by infants and production method thereof Download PDFInfo
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- CN103431411A CN103431411A CN201310423085XA CN201310423085A CN103431411A CN 103431411 A CN103431411 A CN 103431411A CN 201310423085X A CN201310423085X A CN 201310423085XA CN 201310423085 A CN201310423085 A CN 201310423085A CN 103431411 A CN103431411 A CN 103431411A
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Abstract
The invention discloses a milk calcium orally fast dissolving tablet convenient to be taken by infants and a production method of the same and aims at providing a prepared orally fast dissolving tablet which is convenient to be taken by infants for supplementing calcium. The orally fast dissolving tablet containing milk calcium provided by the invention comprises milk calcium for supplementing calcium to infants, tablet support agents, adhesives and other auxiliary materials, wherein the other auxiliary materials can be flavoring agents or other calcium supplements. According to the preparation method, pullulan and Arabic gum or xanthan gum are used as compound adhesives, so that the method of orally taking calcium supplement by infants can be improved due to the prepared orally fast dissolving tablet containing milk calcium ingredients, and requirements on listing standards of related national departments are satisfied.
Description
[technical field]
The present invention relates to the freeze-drying sheet and the production method thereof that contain the milk calcium composition, particularly relate to a kind of containing for not enough milk calcium freeze-drying sheet and the production method thereof that plays supplementary function of infant growth calcium intake.
[technical background]
Along with the development of social technology level, becoming more meticulous in food causes the loss of a large amount of food ingredients, and the calcium deficiency situation appears in increasing infant.
The calcium major function is to promote growing of infant, promotes the growth of bone, the disease that pre-myopia prevention etc. cause because of insufficiency of intake.
Milk calcium is whey inorganic salts concentrates, is the best inorganic Yanyuan of nutritive value and absorption easy to digest.Total inorganic salts amount in cow's milk approximately 0.7%, calcium is about 0.1%.With the calcium in other food, comparing, is top quality calcium source, and this is because the calcium in cow's milk approximately has 70% to be the granular state of casein glue, comprising 40% of the calcium phosphate of collastromin, is combined calcium approximately 30% with casein.Calcium in cow's milk approximately has 30% for solubility calcium, and the ionic calcium of 30% genus is approximately arranged in solubility calcium, and 60% is calcium citrate, and 10% of remainder is calcium phosphate.Be the calcium source that the generally acknowledged element of Nutriology Dept. educational circles the most easily absorbs in the world at present, the human absorptivity is high, and is rich in albumen fragment natural in milk, polypeptide, amino acid and other a large amount of mineral matters.
The sheep milk calcium: calcium phosphorus ration is good.The sheep breast dimension D calcium tablet ratio golden ratio of 1: 8: 1, more approach breast milk, and calcium absorbs better, does not hinder stomach.The fat globule of goat milk and protein particulate only have 1/3 of milk, and even particle size, more easily digested.Contain a large amount of protein structures in goat milk, lactalbumin is identical with breast milk, and not containing causing irritated foreign preteins in milk.So goat milk than the absorption more easy to digest of other dairy produces, can not cause have a stomach upset, the dairy products allergic symptom such as diarrhoea occurs, and is the dairy products that the people of any physique can accept.In the lipid structure of goat milk, carbochain is short, and unsaturated fatty acid content is high, is good emulsified state, more is conducive to body and directly utilizes.Be particularly suitable for the weak crowd of allergic constitution and system.Different from milk of the casein structure of goat milk; Main containing α-2S casein, beta-casein in goat milk, these two kinds of caseins are easily decomposed by yeast; And mainly contain α-1S casein in milk, therefore, to milk allergy and the weak crowd of physique, can accept goat milk fully.Contain 200 multiple nutrients materials in goat milk, it contains with breast milk approaches and enriches mineral matter, trace element, multivitamin, taurine, DHA etc., and the total content of protein, mineral matter and various vitamins is higher than milk.Goat milk contains bioactie agent " adenosine cyclophosphate ", " atriphos " and " EGF growth factor ", these factors have multiple regulatory function in vivo, " adenosine cyclophosphate " is the generally acknowledged cancer-resisting factors of scientific circles, it can make human body metabolism maintain balance, can increase the content of haemocyanin and albumen, increase the premunition of human body; Can improve myocardial nutrition, softening blood vessel, to improvement prevent and treat artery sclerosis, hypertension has very effective effect, simultaneously, the infant uses the goat milk milk calcium to be not easy to get angry.
Healthy correct supplement calcium causes extensive concern day by day.
Existing infant replenishes the calcium and evens the soft capsule supported mainly with the liquid calcium agent out is main, infant taking need to squeeze broken soft capsule to dripping in mouth as, this mode of taking produces the infant to fear to dislike mood.
The advantage of oral instant or disintegrated tablet is that tablet enters into mouthful k disintegration rapidly, is dissolved in saliva
The oral instant tablet form is characterised in that rapid disintegration, and the infant produces the reaction of people's any discomfort taking Shi Buhui, and the milk calcium oral instant-dissolving tablet will be the best infant formulation of replenishing the calcium.
[summary of the invention]
The invention reside in a kind of oral instant-dissolving tablet that contains milk calcium is provided; Another purpose of the present invention is to provide the preparation method of this tablet.
The oral instant preparation that provides a kind of product prepared to contain milk calcium is provided.
The oral instant-dissolving tablet that the present invention contains the milk calcium composition comprises milk calcium composition, sheet shape supporting agent, adhesive and other auxiliary materials, and auxiliary material comprises flavouring and other auxiliary materials of using.
Described milk calcium is the high lactoprotein calcium of pure natural active directly extracted from milk or the high lactoprotein calcium of pure natural active extracted from goat milk.
Described shape presided over the complex that agent is lactose, dextrin and sweet mellow wine, can be that three's mixture can be also the mixture of two kinds wherein, and content is not more than 40%.
The complex that described adhesive is pulullan polysaccharide and Arabic gum, xanthans, can be that three's mixture can be also the mixture of two kinds wherein, and content is not more than 40%.
Wherein said flavouring includes but not limited to that the essence such as various fruity, milk-like taste, honey etc. have that in the food of flavoring function or various essence, one or more have the mixture of flavoring functional food, and its content is not more than 5%.
Described other auxiliary materials comprise that other auxiliary a small amount of compositions of calcareous absorption, as one or more of DHA, prebiotics and vitamin C etc., also can not add, and sheet shape is helped out as galactolipin, xylitol, glycine, Sucralose, dextran etc.
The oral instant tablet preparation method who contains the milk calcium composition described in the present invention is as follows:
Milk calcium is freezing to be saved backup;
To the liquid low temperature that adds appropriate sheet shape supporting agent, adhesive to prepare stable homogeneous in purified water, preserve;
Under low-temperature condition, appropriate milk calcium is joined in the liquid of above-mentioned stable homogeneous, be stirred to uniform and stable;
If need flavouring or other auxiliary materials, add required auxiliary material in aforesaid liquid under low-temperature condition, mix;
The stable homogeneous liquid that above-mentioned steps is obtained divides and is filled in volume required mould fast, the environment stored frozen 15-150 minute below be placed in-70-℃, and in the maintenance mould, liquid is fully curing;
The solidified liquid that above-mentioned steps is obtained is used cryodesiccated technology to make instant of milk calcium freeze-dry orally.
[specific embodiment]
Further describe by the following examples the present invention, this embodiment is of the present invention giving an example, and the invention is not restricted to this.
Preparing the oral instant tablet according to the composition shown in list and quantity is that concrete grammar is as follows:
Milk calcium is freezing to be saved backup;
To the liquid low temperature that adds appropriate sheet shape supporting agent, adhesive to prepare stable homogeneous in purified water, preserve;
Under low-temperature condition, appropriate milk calcium is joined in the liquid of above-mentioned stable homogeneous, be stirred to uniform and stable;
If need flavouring or other auxiliary materials, add required auxiliary material in aforesaid liquid under low-temperature condition, mix;
The stable homogeneous liquid that above-mentioned steps is obtained divides and is filled in volume required mould fast, is placed in the environment stored frozen 15-150 minute below-70 ℃, and in the maintenance mould, liquid is fully curing;
The solidified liquid that above-mentioned steps is obtained is used cryodesiccated technology to make instant of milk calcium freeze-dry orally.
Be listed as follows:
Claims (8)
1. the tablet prepared based on freeze drying that contains milk calcium, comprise that milk calcium, tablet are supportive, adhesive and other auxiliary materials.
2. tablet as claimed in claim 1, is characterized in that described adhesive is the complex of Propiram and Arabic gum or xanthans.
3. tablet as claimed in claim 1, is characterized in that described shape supporting agent is the complex of lactose or dextrin and sweet mellow wine.
4. tablet as claimed in claim 1, is characterized in that described other auxiliary materials are that the auxiliary material milk calcium absorbs composition.Flavouring or other are auxiliary with adhesive or disintegrant etc.
5. as tablet as described in claim 1-4, it is characterized in that in described tablet, milk calcium is the high lactoprotein calcium of pure natural active directly extracted or the high lactoprotein calcium of pure natural active extracted from milk from goat milk.Auxiliary element is one or more of prebiotics, vitamin C or minim DNA or other auxiliary elements.
6. as tablet as described in claim 1-5, it is characterized in that described milk calcium total amount accounts for the tablet total amount and is not less than 50%, sheet supporting agent content is not higher than 40%, and binder content is not higher than 40%.
7. as tablet as described in claim 1-6, it is characterized in that containing not flavouring and other auxiliary materials higher than 15%.
8. the preparation method as described oral instant of claim 1-7 any one is as follows:
(1) by the freezing preservation of milk calcium;
(2) to the liquid low temperature that adds appropriate sheet shape supporting agent, adhesive to prepare stable homogeneous in purified water, preserve;
(3) under low-temperature condition, appropriate (1) is joined in (2), be stirred to uniform and stable;
(4) if need flavouring or other auxiliary materials, under low-temperature condition, in (3), add required auxiliary material, mix;
The stable homogeneous liquid that (5) the 4th steps obtain divides and is filled in volume required mould fast, and as for refrigerated storage 15-150 minute in the environment below-70 ℃, in the maintenance mould, liquid is fully curing;
(6) by the 5th step solidified liquid use cryodesiccated technology to make instant of milk calcium freeze-dry orally.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310423085XA CN103431411A (en) | 2013-09-17 | 2013-09-17 | Milk calcium orally fast dissolving tablet convenient to be taken by infants and production method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310423085XA CN103431411A (en) | 2013-09-17 | 2013-09-17 | Milk calcium orally fast dissolving tablet convenient to be taken by infants and production method thereof |
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| CN103431411A true CN103431411A (en) | 2013-12-11 |
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| CN201310423085XA Pending CN103431411A (en) | 2013-09-17 | 2013-09-17 | Milk calcium orally fast dissolving tablet convenient to be taken by infants and production method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103976248A (en) * | 2014-05-30 | 2014-08-13 | 梁艳红 | Infant milk calcium rice flour and preparation method thereof |
| CN106819105A (en) * | 2016-12-19 | 2017-06-13 | 福建美食品有限公司 | Vacuum freeze drying milk calcium milk beans and preparation method thereof |
| CN106963748A (en) * | 2016-01-13 | 2017-07-21 | 北京量子高科制药科技有限公司 | The vitamin replenisher and preparation method of quick release in oral cavity |
| CN107684078A (en) * | 2017-10-19 | 2018-02-13 | 深圳市德荟堂生物科技有限公司 | A kind of milk calcium product and its production technology |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997048383A1 (en) * | 1996-06-17 | 1997-12-24 | Janssen Pharmaceutica N.V. | Biconvex rapidly disintegrating dosage forms |
| CN102160648A (en) * | 2011-03-11 | 2011-08-24 | 陕西科技大学 | Rapidly disintegrating calcium tablets and preparation method thereof |
-
2013
- 2013-09-17 CN CN201310423085XA patent/CN103431411A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997048383A1 (en) * | 1996-06-17 | 1997-12-24 | Janssen Pharmaceutica N.V. | Biconvex rapidly disintegrating dosage forms |
| CN102160648A (en) * | 2011-03-11 | 2011-08-24 | 陕西科技大学 | Rapidly disintegrating calcium tablets and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 李新玲，等: "活性牛初乳钙片的研制与生产", 《中国乳业》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103976248A (en) * | 2014-05-30 | 2014-08-13 | 梁艳红 | Infant milk calcium rice flour and preparation method thereof |
| CN106963748A (en) * | 2016-01-13 | 2017-07-21 | 北京量子高科制药科技有限公司 | The vitamin replenisher and preparation method of quick release in oral cavity |
| CN106963748B (en) * | 2016-01-13 | 2020-02-21 | 北京量子高科制药科技有限公司 | Vitamin supplement capable of being rapidly released in oral cavity and preparation method thereof |
| CN106819105A (en) * | 2016-12-19 | 2017-06-13 | 福建美食品有限公司 | Vacuum freeze drying milk calcium milk beans and preparation method thereof |
| CN107684078A (en) * | 2017-10-19 | 2018-02-13 | 深圳市德荟堂生物科技有限公司 | A kind of milk calcium product and its production technology |
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Application publication date: 20131211 |