CN107048137A - It is a kind of suitable for low-phosphorus whey albumen powder of Patients with Chronic Renal Disease and preparation method thereof - Google Patents
It is a kind of suitable for low-phosphorus whey albumen powder of Patients with Chronic Renal Disease and preparation method thereof Download PDFInfo
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- CN107048137A CN107048137A CN201710253664.2A CN201710253664A CN107048137A CN 107048137 A CN107048137 A CN 107048137A CN 201710253664 A CN201710253664 A CN 201710253664A CN 107048137 A CN107048137 A CN 107048137A
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract
The invention provides a kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease, the technical scheme devises brand-new albumen powder formula for the constitutive character of patients with chronic kidney disease, on the one hand phosphorus in protein source, Determination of Potassium are improved, on the other hand the nutritional disorders situation for patients with chronic kidney disease, especially dialysis treatment person have matched suitable trace element, it is intended that renal disease patient supplement high-quality protein on the basis of avoid the generation of hyperphosphatemia, while improve its nutrition condition, recovery of invigorating health effectively.Tolerance when product of the present invention is favorably improved patient's treatment is eaten, morbidity and mortality is reduced, improves patients ' life quality etc..On this basis, the present invention preparation method is devised according to the characteristics of formula material, this method is carried out using dry-mixed mode, and reduces energy consumption by the restriction to charging sequence, feeding quantity, products obtained therefrom is lightweight, good water solubility, nutrition retain completely.
Description
Technical field
The present invention relates to the improvement of the composition of functional solid beverage with preparing, and in particular to one kind is applied to chronic renal sufferer
Low-phosphorus whey albumen powder of person and preparation method thereof.
Background technology
Protein is the indispensable nutriment of human body, with the improvement of living standards with the continuous increasing of health perception
By force, daily meals approach can not meet the demand to albumen intake, and albumen powder product arises at the historic moment in this case.
Albumen powder is the solid beverage obtained through means such as separation, extraction, preparations using the food materials rich in protein as raw material, for
Edible mode is that human body supplements protein.The albumen powder product of prior art designs for general population's constitution, generally only has in mind
In the content and absorptivity of protein, but for special constitution crowd, especially nephrosis crowd, the albumen powder of prior art is produced
Product, which are often difficult to meet, to be required.
Kidney trouble often influences the protein and amino acid metabolism of body, particularly with patients with renal failure, saturating
Serum amino acid reduction becomes apparent in analysis treatment；And renal disease patient generally needs to control taking the photograph for nutrients and salinity
Enter, this further have impact on Nutritional Status of Patients, therefore the not enough symptom of renal disease patient generally existing proteinaceous nutrient.It is existing
Although the albumen powder product for having technology can provide high biological value protein, nitrogen balance, albumen powder in nephrotic's body are maintained
Middle phosphorus content is too high, typically in 200~400mg/100g, while albumen is supplemented, often leads to the generation of hyperphosphatemia.And
And, the albumen powder that in the market is sold at present, the difficult situation of generally existing dissolving when reconstituting, and in dissolving with caking
Produce, there is granular sensation when drinking, and local flavor is single, is unfavorable for patient and adheres to drinking for a long time.
The content of the invention
It is contemplated that for the technological deficiency of prior art, there is provided a kind of low-phosphorus whey suitable for Patients with Chronic Renal Disease
Albumen powder and preparation method thereof, high phosphorus blood is easily caused with the albumen powder product for solving prior art during nephrotic is edible
The technical problem of disease.
Another technical problem to be solved by the present invention is that in the albumen powder product dissolving difficulty of prior art, course of dissolution easily
Caking.
To realize above technical purpose, the present invention uses following technical scheme：
A kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease, is made up of the composition of following percentage by weight：Point
From lactalbumin 80~90%, fructose 9~19%, taurine 0.1~0.15%, l-cn 0.1~0.7% is combined dimension life
Element 0.1~0.5%, composite mineral matter 0.1~0.2%, flavoring essence 0.1~0.3%.
Preferably, phosphorus element content is no more than 38mg in albumen powder described in per 100g.
Preferably, Determination of Potassium is no more than 35mg in albumen powder described in per 100g.
Meanwhile, present invention also offers the preparation method of above-mentioned low-phosphorus whey albumen powder, comprise the following steps：
1) B B-complex, composite mineral matter, l-cn, taurine, the flavoring essence of formula ratio are taken, in batch mixer
Mix 10min；
2) take step 1) in 5 times of material gross mass sepg whey albumen add batch mixer continue mix 20min；
3) fructose of the sepg whey albumen of surplus and formula ratio is added into batch mixer to continue to mix 30min, that is, obtains institute
State the low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease.
In above technical scheme, the sepg whey albumen is the product of commercially available, entitled sepg whey albumen powder.
The present invention is from sepg whey albumen as the source of protein, and relative to general proteins powder, its protein content is higher, biological
Utilization rate is up to more than 90%.Moreover, sepg whey albumen is rich in alpha lactalbumin, beta lactoglobulin, lactoferrin, immune ball
Albumen isoreactivity material, helps to adjust body immunity.Sepg whey albumen can containing a large amount of BCAA (branch key amino acid) simultaneously
Nutrient effectively needed for supplement muscle, is to be best suitable for the growth of increase muscle and the restorative nutriment of sufferer at present.More
For importantly, phosphorus, Determination of Potassium are extremely low in the sepg whey albumen that this product is selected, patients with chronic kidney disease can be avoided
The generation of hyperphosphatemia etc. during edible.According to the concrete condition of patient, calculated according to the albumen quantity delivered of inventive formulation,
10~25g products of the present invention are supplemented, patient's protein requirement of one day can be met.
In above technical scheme, select with good taste, sugariness is high, glycemic index is low and carious tooth etc. should not be caused excellent
The fructose composition of point, ensure that the edible safety of renal disease patient as far as possible on the basis of product sweet taste is assigned.Experiment card
Bright, under equal conditions, the blood glucose rise index produced by after by edible glucose is as 100, then edible fruit
After sugar, the blood glucose rise index of human body is only 23, in addition have can as little as 19, and sucrose then be up to 65.Diabetic nephropathy is current
Turn into the second reason of End-stage renal disease.Because there is complicated metabolic disorder in it, once develop into whole end stage renal
Disease, often the treatment than other kidney troubles is more intractable, fructose is selected as the carbohydrate source of product, for timely
Prevent and treat and delay the significant of diabetic nephropathy.
In addition, the present invention is significantly lower than Healthy People in view of the content of taurine in hemodialysis patient body, and taurine
Have protective effect to renal toxicity, thus with the addition of appropriate taurine help lend some impetus to patients with chronic kidney disease constitution it is extensive
It is multiple.And l-cn, it is a kind of amino acid for promoting adipose conversion for energy, many patients such as heart disease, hyperlipemia, kidney
Disease, malnutrition, hypothyroidism disease etc., its carnitine levels is generally low.The supplement of l-cn relies primarily on outer
Source property is supplemented, and the importance of supplement carnitine is no less than replenishing vitamins and mineral element.Haemodialysis once removes 70%
Free carnitine, it is possible to appropriate supplement.The symptoms such as low blood pressure, muscle cramp, anaemia, weakness can be improved, kidney is improved
Patient's life quality.
In above technical scheme, the B B-complex refers to the mixture containing multivitamin composition, Yi Wei cities
Sell product, in the present invention, in the B B-complex at least containing vitamin C, vitamin B1, vitamin B2, vitamin B6,
Folic acid, nicotinic acid, calcium pantothenate, beta carotene.
Vitamin C：The incidence of MHD or patients undergoing peritoneal dialysis hypovitaminosis C is higher, to give and fill
The vitamin of foot, especially wants replenishing vitamins C, because long-term IgA nephrotics can have anaemia, replenishing vitamins C can increase
The absorption of iron.
Vitamin B1：High permeability dialysis film can increase the loss of vitamin B1, therefore Maintenance Hemodialysis Patients are sent out
Raw Vitamin B1 deficiency person is much, and symptom is not obvious during due to Vitamin B1 deficiency, therefore easily failed to pinpoint a disease in diagnosis.Maintenance blood
Dialysis and patients undergoing peritoneal dialysis daily iron supplement vitamin B1 should also be mended additionally in addition to 0.5~1.5 milligram is obtained from food
Fill.
Vitamin B2：Low protein diet and MHD and patients undergoing peritoneal dialysis can occur vitamin B2 and lack on a small quantity
It is weary, but Most patients can be supplemented from diet, be prevention Vitamin B2 deficiency, it is necessary to additionally be supplemented.
Vitamin B6：Either receive expectant treatment or haemodialysis, peritoneal dialysis treatment person, either children or into
People patient, Vitamin B6 deficiency can cause disorder of amino acid metabolism, cause or aggravate some clinical manifestations of end-stage renal failure, go out
Existing peripheral neuropathy, normochromic anemia, immunologic hypofunction, it is susceptible to suffer from infection and central nervous system function disorder etc..Dimension
Holding property dialysis patient and Patients With Kidney Diseases require supplementation with vitamin B6.
Folic acid：Due to non-dialysis and the patients of chronic renal failure of dialysis, internal easily retention toxin, while diet is taken in
It is not enough, lost through dialyzate, there is folic acid deficiency very common.Patients with Chronic Kidney Disease is recommended to answer appropriate Supplement of folic acid.
Nicotinic acid：The nicotinic acid that patients of chronic renal failure low protein diet is provided is less, patient's warp of maintenance dialysis
Dialyzate also has a small amount of nicotinic acid to lose, and recommends patients of chronic renal failure daily iron supplement nicotinic acid.
Calcium pantothenate：Pantothenic acid content in nephrotic's diet is relatively low, and the concentration in serum also has individual difference, can be with
Suitably supplemented.
Beta carotene：The increase of diabetic's oxygen radical can increase low density lipoprotein, cause Atherosclerosis
Change, can also damage glomerulus capilary and cause diabetic nephropathy, beta carotene has the ability of preferable antioxidant radical, daily
Can suitably it supplement.
It, containing a kind of nutritious supplementary pharmaceutical of mineral element is had more than, is also commercially available prod, in this hair that the composite mineral matter, which is,
In bright, ferrous sulfate and zinc gluconate composition are at least contained in the composite mineral matter.The addition of composite mineral matter, is to consider
After occurring to nephrosis, patient's protein is largely lost from urine for a long time, and trace element discharge rate also increases in vivo, therefore causes
Internal Trace Element Imbalance, such as iron, Zn-ef ficiency are reduced.
Ferrous sulfate：Evidence show nearly 70% CKD early stage patient has anaemia, there is a greater amount of iron demands
With synthetic hemoglobin, it is proposed that supplemented daily.
Zinc gluconate：Zn-ef ficiency is the indispensable trace element of human body, and it can strengthen blood cell activity, have antioxygen
Change, anticancer, promotion fertility, the function of strengthening immune system.Research shows that nephrotic not only easily induces painstaking effort in dialysis
Pipe disease, and in the chronic inflammation produced by dialysis procedure, also easily cause and wash nephrosis people's nutrient imbalance, often feel tired out, muscle power
Not good, microelement-supplementing " zinc " washes the inflammation of kidney patient to reduction, quite helpful.
Evidence suggests chronic renal failure can cause protein metabolism abnormal.A large amount of nutritional ingredients in dialysis procedure
Lost including amino acid, protein and water soluble vitamin from dialyzate.Hemodialysis process can circulate amount of amino acid decline,
The hydrolysis of total protein and myogen accelerates, and increases so that total protein and muscle protein are lost, and the element such as serium inorganic phosphorus, potassium is raised.
Also, chronic renal dialysis patient uses low protein diet for a long time, serum protein content is relatively low.
It is cognitive based on above technology, the present invention develop a kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease and
Protein content is up to 80% in its preparation method, the product, can as patient's high-quality protein supplements, egg in product
Sepg whey albumen is derived from vain, and rich in 8 kinds of necessary amino acid of human body and 2 kinds of conditionally essential amino acids, quantity is sufficient, ratio
Suitably.Compared to other products, phosphorus content as little as 38mg/100g, potassium content as little as 35mg/100g, so as to limit phosphorus, potassium
Content, also benefits to improving chronic renal failure dialysis patient disorder of tracelements, so as to reduce the generation of hyperphosphatemia.
Product is rich in multivitamin and trace element, the vitamin that can be needed for edible crowd's supplement；Its preparation method is simple, uses
Dry-mixed mode is produced, and production process energy consumption is low, product weight is light, long shelf-life, nutrition retain complete, transportation and sale cost
It is low, meet low-carbon economy requirement, be adapted to scale industrial production the need for.
Embodiment
The embodiment to the present invention is described in detail below.In order to avoid excessive unnecessary details,
It is will not be described in detail in following examples to belonging to known structure or function.In addition to being defined, institute in following examples
Technology and scientific terminology have the identical meanings being commonly understood by with those skilled in the art of the invention.
Test reagent consumptive material used, is routine biochemistry reagent unless otherwise specified in following examples；The experiment
Method, is conventional method unless otherwise specified；Quantitative test in following examples, is respectively provided with three repetition experiments, as a result
Average；% in following examples, is weight/mass percentage composition unless otherwise instructed.
Embodiment 1
A kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease, is made up of the composition of following percentage by weight：Point
From lactalbumin 85%, fructose 13.15%, taurine 0.15%, l-cn 0.7%, B B-complex 0.5%, grandidierite
Material 0.2%, flavoring essence 0.3%.
The preparation method of above-mentioned albumen powder, comprises the following steps：
1) B B-complex, composite mineral matter, l-cn, taurine, the flavoring essence of formula ratio are taken, in batch mixer
Mix 10min；
2) take step 1) in 5 times of material gross mass sepg whey albumen add batch mixer continue mix 20min；
3) fructose of the sepg whey albumen of surplus and formula ratio is added into batch mixer to continue to mix 30min, that is, obtains institute
State the low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease.
Haemodialysis (MHD) patient, which is investigated, below by way of experimental method takes the nutrition improvement situation after above albumen powder.
This research and design is perspective, random, double blinding, contrast clinical trial, with from The Third Affiliated Hospital of Peking University's hemodialysis
MHD (MHD) patient at center is research object, is randomly divided into two groups, every group 30：
(1) low-phosphorous low potassium diet group：Low-phosphorus whey albumen powder 30g, sets recipe according to ideal body weight individuation, makes albumen
Matter takes in 35kcal/kg/day below 1.0 ± 10%g/kg/day, wherein high-quality protein 50-75%, energy intake 60 years old.
(2) full diet group：Treated using regular diet, recipe is set according to ideal body weight individuation, protein is taken the photograph
Enter 1.0 ± 10%g/kg/day, 35kcal/kg/day below energy intake 60 years old.
Evaluation method：
Patient clinical nutrition condition observation index, except seralbumin, serum prealbumin, hemoglobin, serum amino
Outside the item Index Monitoring protein nutritional status such as acid content, Nutritional Nursing Care evaluation method selects measurement body weight (W), upper-arm circumference
(MAC), arm muscle circumference (MAMC) etc..MAMC can preferable reactive protein storage condition.
All enumeration datas represent that row t is examined, and compares the change of two groups of each indexs, with P with x+s<0.05 and P<0.01
It is used as significant difference and highly significant standard.
Experimental result：
1st, biochemical indicator testing result
After 15 days, test group is compared with control group patients before and after intervention, and hemoglobin has been raised, and serum sodium has dropped
It is low, but not statistically significant (P>0.05).Compared with before intervention, test group seralbumin, prealbumin are raised, and rise has
Significant difference (P ＜ 0.05), after intervention, test group is compared with control group, and there were significant differences (P ＜ 0.05) for prealbumin rise.
Test group serum potassium, phosphorus, urea nitrogen and creatinine are significantly reduced (P ＜ 0.05) after intervention after intervention.Refer to table 1
The chronic renal failure dialysis patient patients before and after intervention nutritive index of table 1 contrasts (x ± s)
* compared with before intervention, p ＜ 0.05, # is compared with control group, p ＜ 0.05
2nd, Serum amino acid changes
The necessary amino acid of serum and histidine content for intervening preceding two groups of chronic renal dialysis patients are low compared with normal value.Intervene
Afterwards, control group intervenes forward and backward serum amino acid without significant changes.After intervention, test group patients serum essential amino acid and group
Histidine content is raised before relatively intervening, and special branched-chain amino acid-leucine, isoleucine and valine content substantially increase, ammonia of reviving
Acid, histidine have also been raised, and the change of remaining amino acid is not statistically significant.Refer to table 2.
Serum must amino acid content contrast before and after the experiment of the patients of chronic renal failure of table 2
* compared with before intervention, p ＜ 0.05, # is compared with control group, p ＜ 0.05
Result of the test shows that patients of chronic renal failure is because being used for a long time low protein diet, serum proteins and amino
Acid content is reduced, and after appropriate protein is provided to patient, serum proteins nutrition condition is obviously improved, it is necessary to which amino acid contains
Amount rise, particularly branched-chain amino acid rise becomes apparent.
Because receiving the patient of dialysis, the element such as serium inorganic phosphorus, potassium is raised.Therefore, breast of this experiment from low-phosphorous, low potassium
Albumin powder, so that the content of phosphorus, potassium is limited, to improving the imbalance of chronic renal failure Rend dialysis patients serum's above element
Also there is certain benefit, so that the generation of hyperphosphatemia is reduced, the SHPT and renal osteodystrophy of reduction
Generation.
Solute effect of the above albumen powder in water is investigated below by way of experimental method.
Test method：
A transparent beaker is taken, the product to be reconstituted (such as by reconstitute 12g/ bags every time) for pouring into fixed amount adds 50ml temperature
Water, is stirred 2-3 minutes, and how is the solubility property of inspection product, if has the phenomenons such as conglomeration, insoluble matter.Take three it is identical
Transparent beaker is reconstituted by the above process, is stood respectively after 6h, 8h, 10h, observes the sedimentation situation of product, and observes product
Clarity.
Experimental result：
Through 2~3 minutes uniform stirrings, product was completely dissolved at a temperature of 45 DEG C, and the phenomenon such as no conglomeration, insoluble matter goes out
It is existing, and after stirring completely, product is in clear state (conglomeration occurs in other like products, and has suspension floccule).See
Examine and stand result for a long time, when placing 6h and 8h, dissolved state still keeps good, does not precipitate, place more than 10h
Afterwards, just start to produce a little sediment, it is seen that (the general 6~8h of like product will be produced the stability and dissolubility of product very well
Raw precipitation, or even shorter time).
Present embodiments provide a kind of suitable for low-phosphorus whey albumen powder of Patients with Chronic Renal Disease and preparation method thereof, the skill
Art scheme devises brand-new albumen powder formula for the constitutive character of patients with chronic kidney disease, on the one hand improves protein
Phosphorus, Determination of Potassium in source, on the other hand for the nutritional disorders feelings of patients with chronic kidney disease, especially dialysis treatment person
Condition have matched suitable trace element, it is intended to avoid the hair of hyperphosphatemia on the basis of renal disease patient supplement high-quality protein
It is raw, at the same improve its nutrition condition, recovery of invigorating health effectively.On this basis, the present embodiment is designed according to the characteristics of formula material
Preparation method, this method is carried out using dry-mixed mode, and reduce energy consumption, institute by the restriction to charging sequence, feeding quantity
Obtain light product weight, good water solubility, nutrition reservation completely.
Embodiment 2
A kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease, is made up of the composition of following percentage by weight：Point
From lactalbumin 80%, fructose 19%, taurine 0.1%, l-cn 0.1%, B B-complex 0.5%, composite mineral matter
0.1%, flavoring essence 0.2%.
The preparation method of above-mentioned albumen powder, comprises the following steps：
1) B B-complex, composite mineral matter, l-cn, taurine, the flavoring essence of formula ratio are taken, in batch mixer
Mix 10min；
2) take step 1) in 5 times of material gross mass sepg whey albumen add batch mixer continue mix 20min；
3) fructose of the sepg whey albumen of surplus and formula ratio is added into batch mixer to continue to mix 30min, that is, obtains institute
State the low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease.
Embodiment 3
A kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease, is made up of the composition of following percentage by weight：Point
From lactalbumin 90%, fructose 9%, taurine 0.15%, l-cn 0.4%, B B-complex 0.2%, composite mineral matter
0.15%, flavoring essence 0.1%.
Embodiment 4
A kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease, is made up of the composition of following percentage by weight：Point
From lactalbumin 83%, fructose 16.5%, taurine 0.1%, l-cn 0.1%, B B-complex 0.1%, complex mineral
Matter 0.1%, flavoring essence 0.1%.
Embodiment 5
A kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease, is made up of the composition of following percentage by weight：Point
From lactalbumin 88.6%, fructose 10.2%, taurine 0.13%, l-cn 0.4%, B B-complex 0.3%, grandidierite
Material 0.17%, flavoring essence 0.2%.
Embodiments of the invention are described in detail above, but the content is only presently preferred embodiments of the present invention,
It is not intended to limit the invention.All any modifications, equivalent substitutions and improvements done in the application range of the present invention etc., all should
Within protection scope of the present invention.
Claims (4)
1. a kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease, it is characterised in that by the composition of following percentage by weight
Composition：Sepg whey albumen 80~90%, fructose 9~19%, taurine 0.1~0.15%, l-cn 0.1~0.7% is multiple
Close vitamin 0.1~0.5%, composite mineral matter 0.1~0.2%, flavoring essence 0.1~0.3%.
2. a kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease according to claim 1, it is characterised in that every
Phosphorus element content is no more than 38mg in albumen powder described in 100g.
3. a kind of low-phosphorus whey albumen powder suitable for Patients with Chronic Renal Disease according to claim 1, it is characterised in that every
Determination of Potassium is no more than 35mg in albumen powder described in 100g.
4. the preparation method of low-phosphorus whey albumen powder described in a kind of claim 1, it is characterised in that comprise the following steps：
1) B B-complex, composite mineral matter, l-cn, taurine, the flavoring essence of formula ratio are taken, is mixed in batch mixer
10min；
2) take step 1) in 5 times of material gross mass sepg whey albumen add batch mixer continue mix 20min；
3) fructose of the sepg whey albumen of surplus and formula ratio is added into batch mixer to continue to mix 30min, that is, obtains described suitable
Low-phosphorus whey albumen powder for Patients with Chronic Renal Disease.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110179036A (en) * | 2019-06-28 | 2019-08-30 | 上海十多生物科技有限公司 | A kind of compound solid beverage and preparation method thereof with promotion cell protein synthesis |
| CN110870512A (en) * | 2019-04-10 | 2020-03-10 | 张璐 | Diet formula for cats suffering from chronic kidney diseases |
| CN111671080A (en) * | 2020-05-14 | 2020-09-18 | 安盛(深圳)医药科技有限公司 | Composition for enhancing immunity, low-phosphorus whey protein powder and preparation method |
| CN112352808A (en) * | 2020-10-14 | 2021-02-12 | 杭州赛能医药科技有限公司 | Low-phosphorus protein food special for diabetic nephropathy patients and preparation method thereof |
| CN114223891A (en) * | 2021-12-27 | 2022-03-25 | 光明乳业股份有限公司 | Special nutritional powder for chronic nephropathy patients and preparation method thereof |
| US20220202048A1 (en) * | 2018-06-27 | 2022-06-30 | Arla Foods Amba | Ph neutral beta-lactoglobulin beverage preparation |
| CN115024495A (en) * | 2022-06-27 | 2022-09-09 | 北京金康普食品科技有限公司 | Nutritional composition for improving calcium and phosphorus metabolism of patients with nephropathy and application thereof |
| CN115226825A (en) * | 2022-06-21 | 2022-10-25 | 肖玉顺 | Functional solid beverage |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20220202048A1 (en) * | 2018-06-27 | 2022-06-30 | Arla Foods Amba | Ph neutral beta-lactoglobulin beverage preparation |
| CN110870512A (en) * | 2019-04-10 | 2020-03-10 | 张璐 | Diet formula for cats suffering from chronic kidney diseases |
| CN110179036A (en) * | 2019-06-28 | 2019-08-30 | 上海十多生物科技有限公司 | A kind of compound solid beverage and preparation method thereof with promotion cell protein synthesis |
| CN111671080A (en) * | 2020-05-14 | 2020-09-18 | 安盛(深圳)医药科技有限公司 | Composition for enhancing immunity, low-phosphorus whey protein powder and preparation method |
| CN112352808A (en) * | 2020-10-14 | 2021-02-12 | 杭州赛能医药科技有限公司 | Low-phosphorus protein food special for diabetic nephropathy patients and preparation method thereof |
| CN114223891A (en) * | 2021-12-27 | 2022-03-25 | 光明乳业股份有限公司 | Special nutritional powder for chronic nephropathy patients and preparation method thereof |
| CN115226825A (en) * | 2022-06-21 | 2022-10-25 | 肖玉顺 | Functional solid beverage |
| CN115024495A (en) * | 2022-06-27 | 2022-09-09 | 北京金康普食品科技有限公司 | Nutritional composition for improving calcium and phosphorus metabolism of patients with nephropathy and application thereof |
| CN115024495B (en) * | 2022-06-27 | 2024-03-22 | 北京金康普食品科技有限公司 | Nutritional composition for improving calcium and phosphorus metabolism of nephrosis patient and application thereof |
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