CN103431327A - Lycium ruthenicum tablets and production method thereof - Google Patents
Lycium ruthenicum tablets and production method thereof Download PDFInfo
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- CN103431327A CN103431327A CN2013103920788A CN201310392078A CN103431327A CN 103431327 A CN103431327 A CN 103431327A CN 2013103920788 A CN2013103920788 A CN 2013103920788A CN 201310392078 A CN201310392078 A CN 201310392078A CN 103431327 A CN103431327 A CN 103431327A
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Abstract
The invention relates to lycium ruthenicum tablets and a production method thereof. The lycium ruthenicum tablets are prepared by taking lycium ruthenicum as a raw material, selecting, washing, extracting, centrifuging for separation, performing membrane concentration, performing vacuum concentration, weighing, drying, grinding, mixing, pelletizing, drying, straightening and tabletting. The purpose of the invention is to solve the problems of high procyanidine loss and high organic solvent residue content when the lycium ruthenicum tablets are produced by a traditional method. The production method is simple and low in cost, the extraction rate of procyanidine reaches more than 92%, and the prepared lycium ruthenicum tablets are convenient to carry, high in added value and free from organic solvent residues.
Description
Technical field
The present invention relates to a kind of berry lozenge and production method thereof, specifically, relate to a kind of black fruit lyceum lozenge and production method thereof.
Background technology
Black fruit lyceum (Lycium ruthenicum Murr) is the perennial shrub plant of Solanaceae Lycium.The black fruit lyceum flavor is sweet, heat is equalled, cleared away heart-fire to property, can be nourishing liver and kidney, benefiting shrewd head, be applicable to soreness and weakness of waist and knees, have a dizzy spell, the symptom such as bleary-eyed, the record black fruit lyceums such as the classical Four-Volume Medical Code of Tibetan medicine and pharmacology, " Jingzhubencao " cure mainly cardiopyretic disease, heart disease, irregular menstruation, menelipsis etc." Uygur medicine will " record Uygur medicine lycium ruthenicum fruit commonly used and root skin treatment urethral calculus, the tinea scabies, the diseases such as gingiva bleeding gingival hemorrhage, among the peoplely make strengthening by means of tonics and the depressor modern scientific research has confirmed above-mentioned saying, and think that black fruit lyceum can reduce cholesterol, excited cerebral nerve, strengthen immunologic function, anti-curing cancers, anti-ageing and the beauty treatment, the black fruit lyceum extract can promote cellular immune function, strengthen the generation of lymphopoiesis and TNF, interleukins II is had to two-way conciliation effect, can eat by the many drinks of diabetes-alleviating patient more, disease loses weight.Black fruit lyceum contains abundant aliphatic acid, protein, free amino acid, mineral element and polysaccharide etc., is conducive to human body directly absorb, and wherein the content of OPC, up to 3.45%, is the plant berry that natural procyanidins content is the highest.OPC is that a class extensively is present in the water colo(u)r in plant, belongs to flavone compound, and anthocyanidin is that human body brings multiple benefit.Fundamentally, anthocyanidin is a kind of strong antioxidant, and it can protect human body to avoid the damage of the harmful substance of free radical.
At present, on market, the utilization of black fruit lyceum is mainly drunk so that dry fruit is soaked, black fruit lyceum main active substances-OPC is not fully utilized, and does not also develop the product of being convenient to market circulation.
Chinese patent application 201010525734.3 Lycium ruthenicum Murr proanthocyanidin products and preparation method thereof, be by the black fruit lyceum fresh fruit be raw material through squeezing the juice, ceramic membrane removal of impurities, macroporous absorbent resin filter, spray-drying obtains the OPC product, there are the shortcomings such as complex process, equipment requirement are higher, spray-drying destructible anthocyanidin in this patent application.
Chinese patent application 201010542518.X method for preparing antioxidant lycium ruthenicum extract, through flooding by black fruit lyceum, colloid mill and high-pressure homogeneous, remove impurity with microfiltration ceramic membrane again, through macroreticular resin separation, spraying or freeze drying, obtain anti-oxidant black fruit lyceum extract, this patent application complex process, equipment requirement are high, spray-drying destructible anthocyanidin, freeze drying increase the shortcomings such as cost.
The black Chinese wolfberry fruit industry of Chinese patent application 2013100627418 practical technique, to deceive matrimony vine ethanol pre-treatment, divide three 70-90 ℃ of hot water lixiviates to make, it is easily residual that this patent application adopts organic solvent pre-treatment to exist, the shortcomings such as hot water lixiviate destructible anthocyanidin.
All there is certain shortcoming in above-mentioned patent application, and especially the destruction of anthocyanidin is reduced Product Activity.
The black fruit lyceum lozenge that does not also adopt in the prior art the black fruit lyceum extract to produce.
The present invention has carried out abundant analysis and research in conjunction with the extracting method of OPC in black fruit lyceum and application prior art thereof, and has carried out a large amount of experimental studies with regard to how improving in black fruit lyceum OPC recovery rate and application thereof.
Summary of the invention
The objective of the invention is, in order to solve the black fruit lyceum lozenge problem that OPC easily loses in process of production, provides a kind of production method of black fruit lyceum lozenge.
A kind of black fruit lyceum lozenge that adopts the black fruit lyceum extract to produce also is provided.
The invention provides a kind of production method of black fruit lyceum lozenge, the concrete technology step is as follows:
(1) choosing fruit: reject the impurity such as immature fruit, silt, stone in fresh black fruit lyceum or black fruit lyceum dry fruit;
(2) clean: the black fruit lyceum after selected is clean with purified rinse water;
(3) extract: at first in holding the extractor of black fruit lyceum, add by weight 1: the pure water of 10-15, and add the 0.03-0.08% ascorbic acid of black fruit lyceum weight ratio and the citric acid of 0.1-0.5%, normal temperature extracts 25-40min and takes out extract; By the black fruit lyceum weight ratio, add 8-12 pure water normal temperature doubly to extract 20-35min again, get extract, merge extracted twice liquid;
(4) centrifugation: by centrifugation under turn at 3500-4500/min of extract condition, the feed intake 20-25 extract doubly of weight of the black fruit lyceum that to obtain solid content be 1.5-5%;
(5) film is concentrated: extract is concentrated through NF membrane, obtain the concentrate that solid content is 12-15%;
(6) Vacuum Concentration: by above-mentioned concentrate, at feed temperature, be 45-55 ℃, the black fruit Chinese holly concentrate that under vacuum 0.6-0.8Mpa condition, concentrated solid content is 30-35%;
(7) batching: add by weight percentage the starch of 10-15% and the citric acid of 0.1-0.5% in above-mentioned black fruit lyceum concentrate;
(8) drying: above-mentioned gained batching is inserted in vacuum dryer, is 40-50 ℃ in temperature, is dried to water content 5-10% under vacuum 0.5-0.8Mpa condition;
(9) pulverize: by above-mentioned dried crushing material to the 150-200 order;
(10) allotment: according to different mouthfeels, need to be allocated mouthfeel;
(11) granulation is dry: according to the w/v ratio of 2: 1, will after the granulation of the alcoholic solution mix and blend of deployed black wolfberry fruit powder and 90-95% concentration, naturally dry;
(12) whole grain, compressing tablet: with 10-20 purpose screen cloth, carry out whole grain compressing tablet.
Can make by said method production a kind of black fruit lyceum lozenge that procyanidin content is high, oxidation resistance is strong.
Advantage of the present invention is: production method of the present invention is simple, and cost is low, and the OPC extraction rate reached is more than 92%, and the product of preparation is easy to carry, and added value is high, and organic solvent-free is residual, has solved that cost is high, the problem of anthocyanidin destructible.
The specific embodiment
Embodiment 1
Selected 100kg black fruit lyceum dry fruit, clean with purified rinse water, sampling be take catechin as standard items, adopts hydrochloric acid-vanillin assay to be measured, and recording procyanidin content is 3.4%.
The black fruit lyceum cleaned up is inserted in extractor, add the pure water of 1500kg, the ascorbic acid of 0.03kg and the citric acid of 0.5kg, extract 30min under normal temperature and obtain extract 1490kg, take out extract, obtain extract 985kg to extracting 20min under the pure water normal temperature that adds 1000kg during black fruit lyceum extracts the extractor of slag again, merge extracted twice liquid 2475kg; By centrifugation under turn 4000/min of the extract of above-mentioned merging condition, the extract 2413kg that to obtain solid content be 1.5%; Said extracted liquid is concentrated through NF membrane, that to obtain solid content be 15% concentrate 240kg; By above-mentioned concentrate, at feed temperature, be 50 ℃ again, the black fruit Chinese holly concentrate 110kg that under vacuum 0.7Mpa condition, concentrated solid content is 33%; Adding the starch of 11kg and adding during the citric acid of 0.33kg inserts vacuum dryer by weight 0.3% by weight 10% in above-mentioned concentrate, in temperature, it is 45 ℃, the black fruit lyceum extract 53.13kg that under vacuum 0.8Mpa condition, dry moisture is 5%, be crushed to 150 orders; Said extracted thing powder is inserted to trough type mixing machine and add the alcoholic solution that the 20L volume ratio is 90%, and the granulation self-heating dries, with the 10 mesh sieves whole grain that sieves, be pressed into tablet and pack and get product.
Get at random finished product 100 grams, take catechin as standard items, adopting hydrochloric acid-vanillin assay to record procyanidin content is 5.9%, through measuring and calculating, by this implementation method, can make the extraction rate reached 92.9% of OPC in black fruit lyceum.
Embodiment 2
Selected 100kg black fruit lyceum dry fruit, clean with purified rinse water, sampling be take catechin as standard items, adopts hydrochloric acid-vanillin assay to be measured, and recording procyanidin content is 3.43%.
The black fruit lyceum cleaned up is inserted in extractor, add the pure water of 1000kg, the ascorbic acid of 0.08kg and the citric acid of 0.1kg, extract 40min under normal temperature and obtain extract 960kg, take out extract, obtain extract 1100kg to extracting 35min under the pure water normal temperature that adds 1200kg during black fruit lyceum extracts the extractor of slag again, merge extracted twice liquid 2060kg; By centrifugation under turn 4500/min of the extract of above-mentioned merging condition, the extract 1620kg that to obtain solid content be 5%; Said extracted liquid is concentrated through NF membrane, that to obtain solid content be 14% concentrate 540kg; By above-mentioned concentrate, at feed temperature, be 55 ℃ again, the black fruit Chinese holly concentrate 160kg that under vacuum 0.8Mpa condition, concentrated solid content is 35%; Adding the starch of 24kg and adding during the citric acid of 0.8kg inserts vacuum dryer by weight 0.5% by weight 15% in above-mentioned concentrate, in temperature, it is 50 ℃, under vacuum 0.6Mpa condition, the dry black fruit lyceum extract 91kg that obtains moisture 10%, be crushed to 200 orders; Said extracted thing powder is inserted to trough type mixing machine and add the alcoholic solution that the 45.5L volume ratio is 93%, and the granulation self-heating dries, with the 15 mesh sieves whole grain that sieves, be pressed into tablet and pack and get product.
Get at random finished product 100 grams, take catechin as standard items, adopting hydrochloric acid-vanillin assay to record procyanidin content is 3.5%, through measuring and calculating, by this implementation method, can make the extraction rate reached 92.85% of OPC in black fruit lyceum.
Embodiment 3
Selected 100kg black fruit lyceum dry fruit, clean with purified rinse water, sampling be take catechin as standard items, adopts hydrochloric acid-vanillin assay to be measured, and recording procyanidin content is 3.38%.
The black fruit lyceum cleaned up is inserted in extractor, add the pure water of 1300kg, the ascorbic acid of 0.05kg and the citric acid of 0.3kg, extract 25min under normal temperature and obtain extract 1285kg, take out extract, obtain extract 780kg to extracting 30min under the pure water normal temperature that adds 800kg during black fruit lyceum extracts the extractor of slag again, merge extracted twice liquid 2065kg; By centrifugation under turn 3500/min of the extract of above-mentioned merging condition, the extract 2010kg that to obtain solid content be 3%; Said extracted liquid is concentrated through NF membrane, that to obtain solid content be 12% concentrate 503kg; By above-mentioned concentrate, at feed temperature, be 45 ℃ again, the black fruit Chinese holly concentrate 168kg that under vacuum 0.6Mpa condition, concentrated solid content is 30%; Adding the starch of 21.8kg and adding during the citric acid of 0.168kg inserts vacuum dryer by weight 0.1% by weight 13% in above-mentioned concentrate, in temperature, it is 40 ℃, under vacuum 0.5Mpa condition, the dry black fruit lyceum extract 85.8kg that obtains moisture 8%, be crushed to 170 orders; Said extracted thing powder is inserted to trough type mixing machine and add the alcoholic solution that the 42.9L volume ratio is 95%, and the granulation self-heating dries, with the 20 mesh sieves whole grain that sieves, be pressed into tablet and pack and get product.
Get at random finished product 100 grams, take catechin as standard items, adopting hydrochloric acid-vanillin assay to record procyanidin content is 3.7%, through measuring and calculating, by this implementation method, can make the extraction rate reached 92.85% of OPC in black fruit lyceum.
Claims (4)
1. the production method of a black fruit lyceum lozenge, the employing black fruit lyceum is raw material, it is characterized in that described production method is that black fruit lyceum is concentrated through choosing fruit, cleaning, extraction, centrifugation, film, Vacuum Concentration, batching, drying, pulverizing, allotment, dry, whole of granulation and compressing tablet make.
2. the production method of a kind of black fruit lyceum lozenge according to claim 1 is characterized in that described production method step is as follows:
(1) choosing fruit: reject the impurity such as immature fruit, silt, stone in fresh black fruit lyceum or black fruit lyceum dry fruit;
(2) clean: the black fruit lyceum after selected is clean with purified rinse water;
(3) extract: at first in holding the extractor of black fruit lyceum, add by weight 1: the pure water of 10-15, and add the 0.03-0.08% ascorbic acid of black fruit lyceum weight ratio and the citric acid of 0.1-0.5%, normal temperature extracts 25-40min and takes out extract; By the black fruit lyceum weight ratio, add 8-12 pure water normal temperature doubly to extract 20-35min again, get extract, merge extracted twice liquid;
(4) centrifugation: by centrifugation under turn at 3500-4500/min of extract condition, obtain the extract that solid content is 1.5-5%;
(5) film is concentrated: extract is concentrated through NF membrane, obtain the concentrate that solid content is 12-15%;
(6) Vacuum Concentration: by above-mentioned concentrate, at feed temperature, be 45-55 ℃, the black fruit Chinese holly concentrate that under vacuum 0.6-0.8Mpa condition, concentrated solid content is 30-35%;
(7) batching: add by weight percentage the starch of 10-15% and the citric acid of 0.1-0.5% in above-mentioned black fruit lyceum concentrate;
(8) drying: above-mentioned gained batching is inserted in vacuum dryer, is 40-50 ℃ in temperature, is dried to water content 5-10% under vacuum 0.5-0.8Mpa condition;
(9) pulverize: by above-mentioned dried crushing material to the 150-200 order;
(10) allotment: according to different mouthfeels, need to be allocated mouthfeel;
(11) granulation is dry: according to the w/v ratio of 2: 1, will after the granulation of the alcoholic solution mix and blend of deployed black wolfberry fruit powder and 90-95% concentration, naturally dry;
(12) whole grain, compressing tablet: with 10-20 purpose screen cloth, carry out whole grain compressing tablet.
3. the production method of a kind of black fruit lyceum lozenge according to claim 1 is characterized in that preferred production stage is as follows:
(1) choosing fruit: reject the impurity such as immature fruit, silt, stone in fresh black fruit lyceum or black fruit lyceum dry fruit;
(2) clean: the black fruit lyceum after selected is clean with purified rinse water;
(3) extract: at first in holding the extractor of black fruit lyceum, add by weight 1: the pure water of 13-15, and add the 0.05-0.08% ascorbic acid of black fruit lyceum weight ratio and the citric acid of 0.3-0.5%, normal temperature extracts 25-30min and takes out extract; By the black fruit lyceum weight ratio, add 8-10 pure water normal temperature doubly to extract 20-30min again, get extract, merge extracted twice liquid;
(4) centrifugation: by centrifugation under turn at 4000-4500/min of extract condition, obtain the extract that solid content is 3-5%;
(5) film is concentrated: extract is concentrated through NF membrane, obtain the concentrate that solid content is 12-14%;
(6) Vacuum Concentration: by above-mentioned concentrate, at feed temperature, be 45-50 ℃, the black fruit Chinese holly concentrate that under vacuum 0.7-0.8Mpa condition, concentrated solid content is 30-33%;
(7) batching: add by weight percentage the starch of 10-13% and the citric acid of 0.3-0.5% in above-mentioned black fruit lyceum concentrate;
(8) drying: above-mentioned gained batching is inserted in vacuum dryer, is 40-45 ℃ in temperature, is dried to water content 5-8% under vacuum 0.6-0.8Mpa condition;
(9) pulverize: by above-mentioned dried crushing material to the 150-170 order;
(10) allotment: according to different mouthfeels, need to be allocated mouthfeel;
(11) granulation is dry: according to the w/v ratio of 2: 1, will after the granulation of the alcoholic solution mix and blend of deployed black wolfberry fruit powder and 93-95% concentration, naturally dry;
(12) whole grain, compressing tablet: with 15-20 purpose screen cloth, carry out whole grain compressing tablet.
4. a kind of black fruit lyceum lozenge made according to claim 1,2 or 3 described method productions.
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| CN103829242A (en) * | 2014-03-06 | 2014-06-04 | 中国科学院西北高原生物研究所 | Health-care food containing fruit of nitraria red pigment |
| CN103919232A (en) * | 2014-05-06 | 2014-07-16 | 中国科学院西北高原生物研究所 | Lycium ruthenicum effervescent tablet |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1297947A (en) * | 1999-12-01 | 2001-06-06 | 上海国宝企业发展中心 | Preparation of extracted active component of Lycium chinense |
| CN1899446A (en) * | 2006-07-05 | 2007-01-24 | 吉林农业大学 | Wolfberry fruit tablet health product and its preparing method |
| CN101530207A (en) * | 2009-04-14 | 2009-09-16 | 中国农业科学院农产品加工研究所 | Medlar nutrient chewable tablet and preparation method thereof |
| CN101564169A (en) * | 2009-05-15 | 2009-10-28 | 中国科学院昆明植物研究所 | Medlar nutriment, and preparation and application thereof |
| CN102240035A (en) * | 2011-05-27 | 2011-11-16 | 银川泰丰生物科技有限公司 | Method for preparing wolfberry extract health-care granules |
| CN103082291A (en) * | 2013-02-28 | 2013-05-08 | 上海基赛生物医药科技有限公司 | Industrial application technology of lycium ruthenicum fruit |
-
2013
- 2013-08-27 CN CN2013103920788A patent/CN103431327A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1297947A (en) * | 1999-12-01 | 2001-06-06 | 上海国宝企业发展中心 | Preparation of extracted active component of Lycium chinense |
| CN1899446A (en) * | 2006-07-05 | 2007-01-24 | 吉林农业大学 | Wolfberry fruit tablet health product and its preparing method |
| CN101530207A (en) * | 2009-04-14 | 2009-09-16 | 中国农业科学院农产品加工研究所 | Medlar nutrient chewable tablet and preparation method thereof |
| CN101564169A (en) * | 2009-05-15 | 2009-10-28 | 中国科学院昆明植物研究所 | Medlar nutriment, and preparation and application thereof |
| CN102240035A (en) * | 2011-05-27 | 2011-11-16 | 银川泰丰生物科技有限公司 | Method for preparing wolfberry extract health-care granules |
| CN103082291A (en) * | 2013-02-28 | 2013-05-08 | 上海基赛生物医药科技有限公司 | Industrial application technology of lycium ruthenicum fruit |
Cited By (21)
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| CN103652928B (en) * | 2013-12-27 | 2015-01-07 | 中国农业科学院农产品加工研究所 | Medlar buccal preparation and preparation method thereof |
| CN103734420A (en) * | 2013-12-27 | 2014-04-23 | 兴义市东泰天然果蔬开发有限公司 | Rosaroxbunghii and dianthus chinensis tea and making method for same |
| CN103652928A (en) * | 2013-12-27 | 2014-03-26 | 中国农业科学院农产品加工研究所 | Medlar buccal preparation and preparation method thereof |
| CN103734420B (en) * | 2013-12-27 | 2015-06-03 | 兴义市东泰天然果蔬开发有限公司 | Rosaroxbunghii and dianthus chinensis tea and making method for same |
| CN103829242A (en) * | 2014-03-06 | 2014-06-04 | 中国科学院西北高原生物研究所 | Health-care food containing fruit of nitraria red pigment |
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| CN103932081A (en) * | 2014-03-25 | 2014-07-23 | 金诃藏药股份有限公司 | Red-and-black wolfberry double-layer tablet and preparation method thereof |
| CN103947967A (en) * | 2014-04-21 | 2014-07-30 | 青海睿元药物研究所有限责任公司 | Black red double-color lycium barbarum slice and preparation method thereof |
| CN103947967B (en) * | 2014-04-21 | 2015-12-02 | 青海睿元药物研究所有限责任公司 | Double-colored dark red fruit matrimony vine sheet and preparation method thereof |
| CN103919232A (en) * | 2014-05-06 | 2014-07-16 | 中国科学院西北高原生物研究所 | Lycium ruthenicum effervescent tablet |
| CN104248036A (en) * | 2014-09-19 | 2014-12-31 | 青海诺蓝杞生物科技开发有限公司 | Lycium ruthenicum Murr procyanidine effervescent tablet and production method thereof |
| CN104783088A (en) * | 2015-03-26 | 2015-07-22 | 赵君 | Preparation method for pure Lycium ruthenicum Murr powder tablet and pure Lycium ruthenicum Murr powder tablet |
| CN104783292B (en) * | 2015-04-15 | 2017-03-01 | 沈阳药科大学 | Lycium ruthenicum Murr. effervescent tablet and preparation method thereof |
| CN104783292A (en) * | 2015-04-15 | 2015-07-22 | 沈阳药科大学 | Lycium ruthenicum Murr effervescent tablet and preparation method thereof |
| CN105105123A (en) * | 2015-09-06 | 2015-12-02 | 青海之也科技咨询服务有限公司 | Lycium ruthenicum health tablet and preparation method thereof |
| CN105192606A (en) * | 2015-10-21 | 2015-12-30 | 宁夏林业研究所股份有限公司 | Preparation method of leaf Lycium chinense Miller buccal tablet |
| CN105249241A (en) * | 2015-11-13 | 2016-01-20 | 哈尔滨市兴利米制品有限公司 | Composite quick-eatable black coarse cereal nutrition powder and making method thereof |
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| WO2019007237A1 (en) | 2017-07-04 | 2019-01-10 | 青海睿元药物研究所有限责任公司 | Lycium ruthenicum effervescent tablet and preparation method therefor |
| CN107751871A (en) * | 2017-09-29 | 2018-03-06 | 杞源堂（宁夏）生物科技有限公司 | A kind of selenium-rich lycium ruthenicum lozenge and preparation method thereof |
| CN111534410A (en) * | 2020-06-13 | 2020-08-14 | 劲牌有限公司 | Preparation method and application of lycium ruthenicum concentrated solution |
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