CN102898411A - Proanthocyanidin extraction technology - Google Patents
Proanthocyanidin extraction technology Download PDFInfo
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- CN102898411A CN102898411A CN 201110211044 CN201110211044A CN102898411A CN 102898411 A CN102898411 A CN 102898411A CN 201110211044 CN201110211044 CN 201110211044 CN 201110211044 A CN201110211044 A CN 201110211044A CN 102898411 A CN102898411 A CN 102898411A
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Abstract
The invention belongs to the medicine processing field, and concretely relates to a proanthocyanidin extraction technology. The proanthocyanidin extraction technology has the advantages of low cost, high efficiency and no pollution. The technology comprises the following steps: cleaning and drying lichee pericarp, crushing the dried lichee pericarp with a crusher into powder, adding the lichee pericarp powder to a 60-80% ethanol solution, carrying out water-bath extraction at 50-70DEG C for 60-120min, filtering the obtained extract liquid, carrying out reduced pressure ethanol recovery through using a rotary evaporator, allowing the obtained water phase to go through an AB-8 macroporous adsorption resin, eluting with distilled water having an amount 9 times higher than that of the water phase and 50% ethanol having an amount 9 times higher than that of the water phase, carrying out vacuum concentration of the obtained eluate at 50DEG C, and freeze-drying to form powder.
Description
Technical field:
The invention belongs to the medicine manufacture field, more particularly, relate to a kind of extraction process of pycnogenols.
Background technology:
Lichee is southern china special product fruit, and is nutritious because of it, and the sweet meat of distinguishing the flavor of is tender, and quality is extremely excellent and be described as " treasure of China ".Lichee contains abundant sugar, protein, multivitamin, fat, citric acid, pectin and phosphorus, iron etc., cerebral tissue there is the effect of taking a tonic or nourishing food to build up one's health, can obviously improves insomnia, forgetful, the disease such as god is tired, help the enhancing body immunologic function, improving resistance against diseases, is the fruit to the human body beneficial.In the suitability for industrialized production of lichee, a large amount of litchi rinds do not obtain effective development and utilization as byproduct, usually be used as waste and abandon, litchi rind also has very high biochemical activity in fact, is rich in abundant anthocyan, proanthocyanidins, fatty compounds and multiple nutritional components.
Pycnogenols is a kind of Vitamin P complex that special molecular structure is arranged, and is the most effective natural antioxidants of free radical in the removing human body of generally acknowledging in the world at present.Be generally the reddish-brown powder, little, the puckery of gas, water-soluble and most organic solvent.Pycnogenols is a kind of new and effective antioxidant, is the most potent free-radical scavengers of finding so far, has very strong activity in vivo, and it can protect the blood circulation of human body; Prevent collagenase and elastoser to banning the Degradation of tissue, thereby be conducive to keep the elasticity of skin, the effect of performance anti aging effect; Can strengthen ascorbic effect, prolong the time that effect occurs vitamins C in human body.
Summary of the invention:
The present invention is exactly for the problems referred to above, and a kind of efficient, free of contamination pycnogenols extraction process is provided.
In order to realize above-mentioned purpose of the present invention, processing step of the present invention is: with Fructus Litchi cleaning, drying, dried litchi rind is ground into powder with pulverizer, the litchi rind powder is added to carries out water-bath in 60～80% the ethanolic soln and extract, extracting temperature is 50～70 ℃, extraction time is 60～120min, then with behind the extracting liquid filtering, use the Rotary Evaporators decompression recycling ethanol, AB-8 macroporous adsorbent resin on the water, adopt 10 times of amount distilled water and 50% ethanol distribution wash-out, elutriant is at 50 ℃ of vacuum concentration, lyophilize powdered.
Beneficial effect of the present invention:
1. the present invention recycles litchi rind, has both reduced the pollution of environment, has realized again the full use to resource;
2. the used raw material of the present invention is litchi rind, greatly reduces production cost;
The present invention to the extraction rate reached of pycnogenols to 1.2%.
Embodiment:
Processing step of the present invention is: with Fructus Litchi cleaning, drying, dried litchi rind is ground into powder with pulverizer, the litchi rind powder is added to carries out water-bath in 60～80% the ethanolic soln and extract, extracting temperature is 50～70 ℃, extraction time is 60～120min, then with behind the extracting liquid filtering, use the Rotary Evaporators decompression recycling ethanol, AB-8 macroporous adsorbent resin on the water, adopt 10 times of amount distilled water and 50% ethanol distribution wash-out, elutriant is at 50 ℃ of vacuum concentration, lyophilize powdered.
As a kind of preferred version, processing parameter is: alcohol concn 68%, extract 61 ℃ of temperature, and extraction time is 105min.
Pycnogenols is polymerized by catechin, l-Epicatechol and the derivative thereof of different numbers, can adopt methyl alcohol, ethanol and acetone to extract the litchi rind pycnogenols, three kinds of solvents all can permeate vegetable cell to some extent, combine with pycnogenols, with its stripping.The extraction effect of three kinds of solvents is more or less the same, but because the toxicity of methyl alcohol and acetone is higher, if remove not exclusively after extracting, can damage human body, so the present invention selects ethanol as the extraction solvent of litchi rind pycnogenols here.
Alcohol concn, extraction temperature and extraction time are all influential to the extraction effect of pycnogenols, can see Table 1.
Table 1 three factors are on the impact of pycnogenols extraction effect
Claims (2)
1. pycnogenols volume extraction process, it is characterized in that processing step of the present invention is: with Fructus Litchi cleaning, drying, dried litchi rind is ground into powder with pulverizer, the litchi rind powder is added to carries out water-bath in 60～80% the ethanolic soln and extract, extracting temperature is 50～70 ℃, extraction time is 60～120min, then with behind the extracting liquid filtering, use the Rotary Evaporators decompression recycling ethanol, AB-8 macroporous adsorbent resin on the water, adopt 10 times of amount distilled water and 50% ethanol distribution wash-out, elutriant is at 50 ℃ of vacuum concentration, lyophilize powdered.
2. the extraction process of a kind of pycnogenols according to claim 1 is characterized in that processing parameter is: alcohol concn 68%, extract 61 ℃ of temperature, and extraction time is 105min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110211044 CN102898411A (en) | 2011-07-27 | 2011-07-27 | Proanthocyanidin extraction technology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110211044 CN102898411A (en) | 2011-07-27 | 2011-07-27 | Proanthocyanidin extraction technology |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102898411A true CN102898411A (en) | 2013-01-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110211044 Pending CN102898411A (en) | 2011-07-27 | 2011-07-27 | Proanthocyanidin extraction technology |
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| CN (1) | CN102898411A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107382945A (en) * | 2017-02-27 | 2017-11-24 | 长沙理工大学 | The method for extracting OPC |
| CN107556284A (en) * | 2017-10-31 | 2018-01-09 | 桂林纽泰生物科技有限公司 | The method that OPC is extracted from litchi rind |
| CN107721965A (en) * | 2017-10-31 | 2018-02-23 | 桂林纽泰生物科技有限公司 | The extraction process of litchi rind OPC |
| CN113218940A (en) * | 2021-04-29 | 2021-08-06 | 邹好 | Low coffee ring effect freshness visualization sensor array and preparation method thereof |
-
2011
- 2011-07-27 CN CN 201110211044 patent/CN102898411A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107382945A (en) * | 2017-02-27 | 2017-11-24 | 长沙理工大学 | The method for extracting OPC |
| CN107556284A (en) * | 2017-10-31 | 2018-01-09 | 桂林纽泰生物科技有限公司 | The method that OPC is extracted from litchi rind |
| CN107721965A (en) * | 2017-10-31 | 2018-02-23 | 桂林纽泰生物科技有限公司 | The extraction process of litchi rind OPC |
| CN113218940A (en) * | 2021-04-29 | 2021-08-06 | 邹好 | Low coffee ring effect freshness visualization sensor array and preparation method thereof |
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| C06 | Publication | ||
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| DD01 | Delivery of document by public notice |
Addressee: Zhou Yitong Document name: Notification that Application Deemed to be Withdrawn |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130130 |