CN103430022A - 诊断方法 - Google Patents

诊断方法 Download PDF

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Publication number
CN103430022A
CN103430022A CN2012800132832A CN201280013283A CN103430022A CN 103430022 A CN103430022 A CN 103430022A CN 2012800132832 A CN2012800132832 A CN 2012800132832A CN 201280013283 A CN201280013283 A CN 201280013283A CN 103430022 A CN103430022 A CN 103430022A
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CN
China
Prior art keywords
level
compound
sample
determining
liver cancer
Prior art date
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Pending
Application number
CN2012800132832A
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English (en)
Chinese (zh)
Inventor
西蒙·D·泰勒-罗宾森
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Ip2ipo Innovations Ltd
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Imperial Innovations Ltd
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Filing date
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Application filed by Imperial Innovations Ltd filed Critical Imperial Innovations Ltd
Publication of CN103430022A publication Critical patent/CN103430022A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/08—Hepato-biliairy disorders other than hepatitis
    • G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing
    • Y10T436/173845—Amine and quaternary ammonium
    • Y10T436/174614—Tertiary amine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
    • Y10T436/201666—Carboxylic acid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN2012800132832A 2011-01-31 2012-01-31 诊断方法 Pending CN103430022A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1101667.2A GB201101667D0 (en) 2011-01-31 2011-01-31 Diagnostic method
GB1101667.2 2011-01-31
PCT/GB2012/000100 WO2012104585A2 (en) 2011-01-31 2012-01-31 Diagnostic method

Publications (1)

Publication Number Publication Date
CN103430022A true CN103430022A (zh) 2013-12-04

Family

ID=43824891

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2012800132832A Pending CN103430022A (zh) 2011-01-31 2012-01-31 诊断方法

Country Status (9)

Country Link
US (1) US20140134751A1 (https=)
EP (1) EP2671077A2 (https=)
JP (1) JP2014505254A (https=)
KR (1) KR20140007414A (https=)
CN (1) CN103430022A (https=)
AP (1) AP2013007084A0 (https=)
AU (1) AU2012213244A1 (https=)
GB (1) GB201101667D0 (https=)
WO (1) WO2012104585A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111638324A (zh) * 2020-05-28 2020-09-08 长沙都正生物科技有限责任公司 一种冠心病诊断生物标记物组合及其应用

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201307256D0 (en) * 2013-04-22 2013-05-29 Imp Innovations Ltd Diagnostic method
JP7230335B2 (ja) * 2018-04-02 2023-03-01 味の素株式会社 取得方法、算出方法、評価装置、算出装置、評価プログラム、算出プログラム、記録媒体、及び評価システム
GB202102105D0 (en) * 2021-02-15 2021-03-31 Novabiotics Ltd Prognostic method
CN114414611B (zh) * 2022-01-25 2025-07-15 嘉兴大学 一种肝癌微血管侵犯鉴别模型的构建方法及肝癌微血管侵犯预测值的测试方法
WO2025008463A1 (en) 2023-07-06 2025-01-09 Numares Ag Use of a marker set for determining the risk of an individual to have hepatocellular carcinoma
KR102881746B1 (ko) * 2024-04-19 2025-11-06 주식회사 티엠에이오 인체내 트리메틸아민-n-옥사이드(tmao) 진단을 위한 키트 및 항체의 이용

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1428435A (zh) * 2001-12-27 2003-07-09 张抗 肝癌诊断、监护及肝硬化监护试剂盒
CN101464271A (zh) * 2007-12-19 2009-06-24 苏州艾杰生物科技有限公司 甘氨酸诊断/测定试剂盒及甘氨酸的浓度测定方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070015146A1 (en) * 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
AU2003255643A1 (en) * 2003-06-05 2005-01-21 Vincent Thomas Armbruster Measuring system for measuring at least one characteristic of a biological tissue and method for fixing a biological tissue to a measuring system of this type
US7373256B2 (en) * 2005-04-19 2008-05-13 Nicholson Jeremy K Method for the identification of molecules and biomarkers using chemical, biochemical and biological data

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1428435A (zh) * 2001-12-27 2003-07-09 张抗 肝癌诊断、监护及肝硬化监护试剂盒
CN101464271A (zh) * 2007-12-19 2009-06-24 苏州艾杰生物科技有限公司 甘氨酸诊断/测定试剂盒及甘氨酸的浓度测定方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JUAN WANG ET AL.: "1H-NMR-based metabolomics of tumor tissue for the metabolic characterization of rat hepatocellularcarcinoma formation and metastasis", 《TUMOR BIOL.》 *
ZONG-FANG LI ET AL.: "Gas chromatography/time-of-flight mass spectrometry-based metabonomics of hepatocarcinoma in rats with lung metastasis: elucidation of the metabolic characteristics of hepatocarcinoma at formation and metastasis", 《RAPID COMMUNICATIONS IN MASS SPECTROMETRY》 *
ZONG-FANG LI ET AL.: "Gas chromatography/time-of-flight mass spectrometry-based metabonomics of hepatocarcinoma in rats with lung metastasis: elucidation of the metabolic characteristics of hepatocarcinoma at formation and metastasis", 《RAPID COMMUNICATIONS IN MASS SPECTROMETRY》, vol. 24, no. 18, 24 September 2010 (2010-09-24) *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111638324A (zh) * 2020-05-28 2020-09-08 长沙都正生物科技有限责任公司 一种冠心病诊断生物标记物组合及其应用
CN111638324B (zh) * 2020-05-28 2023-08-11 长沙都正生物科技有限责任公司 一种冠心病诊断生物标记物组合及其应用

Also Published As

Publication number Publication date
WO2012104585A2 (en) 2012-08-09
US20140134751A1 (en) 2014-05-15
WO2012104585A3 (en) 2012-12-27
JP2014505254A (ja) 2014-02-27
EP2671077A2 (en) 2013-12-11
AU2012213244A1 (en) 2013-09-05
AP2013007084A0 (en) 2013-08-31
GB201101667D0 (en) 2011-03-16
KR20140007414A (ko) 2014-01-17

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SE01 Entry into force of request for substantive examination
C53 Correction of patent of invention or patent application
CB03 Change of inventor or designer information

Inventor after: Taylor-robinson Simon D

Inventor after: Shahid Aziz Kahn

Inventor after: Mohamed - I - F - Sheriff

Inventor before: Taylor-robinson Simon D

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: TAYLOR-ROBINSON SIMON D. TO: TAYLOR-ROBINSON SIMON D. SHAHID AZIZ KAHN SHARIFF MOHAMED I. F.

AD01 Patent right deemed abandoned

Effective date of abandoning: 20170201

C20 Patent right or utility model deemed to be abandoned or is abandoned