CN103417761A - Medicinal liquor for treatment of fracture and osteoporosis - Google Patents
Medicinal liquor for treatment of fracture and osteoporosis Download PDFInfo
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- CN103417761A CN103417761A CN2013103652939A CN201310365293A CN103417761A CN 103417761 A CN103417761 A CN 103417761A CN 2013103652939 A CN2013103652939 A CN 2013103652939A CN 201310365293 A CN201310365293 A CN 201310365293A CN 103417761 A CN103417761 A CN 103417761A
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- cortex eucommiae
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Abstract
The invention discloses medicinal liquor for the treatment of fracture and osteoporosis and a preparation method thereof. The medicinal liquor comprises Chinese banana root, creeping woodsorrel herb, Himalayan teasel root, pseudo-ginseng, fructus psoraleae, epimedium herb, and eucommia bark. The preparation method includes: slicing the eucommia bark, stir-frying the bark with salt water, mixing the fried bark with rough powders of other crushed herbs, soaking the mixture in liquor for 3-15 days, allowing for slow percolation, collecting percolate, allowing for standing, and performing filtering to obtain the medicinal liquor. The medical liquor has the advantages of fine curative effect, no toxic and side effects, convenience in use and the like.
Description
Technical field
The present invention relates to a kind of preparation method for the treatment of fracture, osteoporotic medicated wine, belong to the technical field of medicine.
Background technology
The osteopathia such as fracture, osteoporosis, osteoarthritis are old people's susceptible disease.China is the maximum country of patients with osteoporosis in the world, and patient 6,000 ten thousand is approximately arranged, Gukang capsule list marketing more than 10 year, and curative effect has obtained the favorable comment of extensive patients.In order to meet patient's higher demand, JP is sent out and is made medicinal medicated wine, to meet the drink demand of health protection of some patients were.Compendium of Material Medica thinks, wine has capable medicine gesture, and promoting blood circulation, wet dissipation gas, except functions such as the wind therapeutic method to keep the adverse QI flowing downwardss.Medicated wine is conducive to absorption of human body, and particularly for osteoarthritis, curative effect is better.Select the additional Cortex Eucommiae of basic medical material and the Herba Epimedii of Gukang capsule to prepare bone injury medicated wine, the stripping that has improved medicament effective component on the one hand, strengthened the promoting blood circulation to remove obstruction in the collateral effect, more strengthened on the other hand the effect of invigorating the liver and kidney, bone and muscle strengthening.
Summary of the invention
The object of the invention is to provide a kind of fracture, osteoporotic medicated wine and preparation method thereof for the treatment of, and solves the not enough of prior art existence and increases a kind of bone health novel form.
Technical scheme of the present invention is: a kind of fracture, osteoporotic medicated wine and preparation method thereof for the treatment of:
Concrete grammar is as follows: by the crude drug of following weight proportioning, Radix Musae 300g ~ 1200g, Herba Oxalidis Corniculatae 200g ~ 800g, Radix Dipsaci 150g ~ 600g, Radix Notoginseng 75g ~ 300g, Fructus Psoraleae 300g ~ 1200g, Herba Epimedii 100g ~ 400g, Cortex Eucommiae 100g ~ 400g, make as follows:
A, the Cortex Eucommiae in the above-mentioned raw materials medicine is cut into thread, carry out salt and process rear standbyly, obtain a product;
B, by other crude drug except the Cortex Eucommiae, be ground into coarse powder standby, obtain the b product;
C, get a product and b product and mix, with 10000 ~ 50000ml Chinese liquor, make solvent, after soaking 3 ~ 15 days, with 1 ~ 10ml per minute, slowly percolation, collect percolate, standing, and filtration, obtain the c product;
D, the c product are distributed into to 100ml or 250ml or 500ml, obtain finished product.
The present invention is on former Gukang capsule formula basis, by repeatedly testing, contrast, conclude, summing up, and the Chinese medicine tincture developed.This dosage form is compared with capsule, all obviously be better than capsule on drug dissolution, bioavailability, in former Gukang capsule technique, Fructus Psoraleae is adopted to decocting process, gained extractum is high temperature drying again, makes in Fructus Psoraleae active ingredient psoralen and isopsorapen content loss larger.This law has adopted with soaking in Chinese liquor and has carried out the percolation extraction process, and psoralen and isopsorapen content is obviously improved, and has improved medical material and has utilized level.
Different Extraction Method experimental result table
In addition, the finished product that this technique is made is medicated wine, with capsule, compares, and at dissolution, bioavailability, stability of drug products, all obviously is better than capsule.In addition, we have increased tonic Herba Epimedii and the Cortex Eucommiae in original prescription, and Herba Epimedii has warming the kidney to invigorate YANG, bone and muscle strengthening, and the effect of wind-damp dispelling, for the muscles and bones of deficiency of the liver and kindey, arthralgia pain, rheumatism contracture numbness waits disease; The Cortex Eucommiae is longer than invigorating the liver and kidney, bone and muscle strengthening, and for the soreness of waist and knee joint of deficiency of the liver and kindey, the diseases such as flaccidity and weakness of the lower limbs, all medicines share, and have more nourishing the liver and kidney, bone and muscle strengthening, the merit of removing obstruction in the collateral to relieve pain, better for old people's person who suffer from deficiency of kidney Yang effect.
Different prescription therapeutic effect summary sheets
The specific embodiment:
Embodiment 1:
Take off the crude drug of stating weight proportion, Radix Musae 300g, Herba Oxalidis Corniculatae 200g, Radix Dipsaci 150g, Radix Notoginseng 75g, Fructus Psoraleae 300g, Herba Epimedii 100g, Cortex Eucommiae 100g, preparation as follows:
A, the Cortex Eucommiae in the above-mentioned raw materials medicine is cut into thread, carry out salt and process rear standbyly, obtain a product;
B, by other crude drug except the Cortex Eucommiae, be ground into coarse powder standby, obtain the b product;
C, get a product and b product and mix, with 10000ml Chinese liquor (spirituosity 40%), make solvent, after soaking 3 days, with the flow velocity of 3ml per minute, slowly percolation, collect percolate, standing, and filtration, obtain the c product;
D, the c product are distributed into to 250ml, obtain finished product.
Embodiment 2:
Take off the crude drug of stating weight portion, Radix Musae 600g, Herba Oxalidis Corniculatae 400g, Radix Dipsaci 300g, Radix Notoginseng 150g, Fructus Psoraleae 600g, Herba Epimedii 200g, Cortex Eucommiae 200g, preparation as follows:
A, the Cortex Eucommiae in the above-mentioned raw materials medicine is cut into thread, carry out salt and process rear standbyly, obtain a product;
B, by other crude drug except the Cortex Eucommiae, be ground into coarse powder standby, obtain the b product;
C, get a product and b product and mix, with 20000ml Chinese liquor (spirituosity 50%), make solvent, after soaking 5 days, with 5ml per minute, slowly percolation, collect percolate, standing, and filtration, obtain the c product;
D, the c product are distributed into to 500ml, obtain finished product.
Embodiment 3:
Take off the crude drug of stating weight portion, Radix Musae 1200g, Herba Oxalidis Corniculatae 800g, Radix Dipsaci 600g, Radix Notoginseng 300g, Fructus Psoraleae 1200g, Herba Epimedii 400g, Cortex Eucommiae 400g, preparation as follows:
A, the Cortex Eucommiae in the above-mentioned raw materials medicine is cut into thread, carry out salt and process rear standbyly, obtain a product;
B, by other crude drug except the Cortex Eucommiae, be ground into coarse powder standby, obtain the b product;
C, get a product and b product and mix, with 40000ml Chinese liquor (spirituosity 60%), make solvent, after soaking 10 days, with 5ml per minute, slowly percolation, collect percolate, standing, and filtration, obtain the c product;
D, the c product are distributed into to 500ml, obtain finished product.
Finished product is used for the treatment of fracture.Blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain are arranged, channels sootheing and network vessel quickening, the invigorating the kidney and strengthening the bones effect, be used for the treatment of that fracture, bone pass skill are scorching, osteoporosis belongs to deficiency of the liver and kindey, meridians stasis blocking person.Oral a 10 ~ 20ml, 3 times on the one.
Claims (4)
1. treat fracture, osteoporotic medicated wine for one kind, it is characterized in that: by the crude drug of following weight proportioning, Radix Musae 300g ~ 1200g, Herba Oxalidis Corniculatae 200g ~ 800g, Radix Dipsaci 150g ~ 600g, Radix Notoginseng 75g ~ 300g, Fructus Psoraleae 300g ~ 1200g, Herba Epimedii 100g ~ 400g, Cortex Eucommiae 100g ~ 400g, make as follows:
A, the Cortex Eucommiae in the above-mentioned raw materials medicine is cut into thread, carry out salt and process rear standbyly, obtain a product;
B, by other crude drug except the Cortex Eucommiae, be ground into coarse powder standby, obtain the b product;
C, get a product and b product and mix, with 10000 ~ 50000ml Chinese liquor, make solvent, soak, slowly percolation, collect percolate, standing, and filtration, obtain the c product;
D, the c product are distributed into to 100ml or 250ml or 500ml, obtain finished product.
2. medicated wine claimed in claim 1, it is characterized in that: described crude drug is Radix Musae 600g, Herba Oxalidis Corniculatae 400g, Radix Dipsaci 300g, Radix Notoginseng 150g, Fructus Psoraleae 600g, Herba Epimedii 200g, Cortex Eucommiae 200g, makes 20000ml.
3. medicated wine claimed in claim 1, it is characterized in that: described Chinese liquor spirituosity degree is 40% ~ 60%.
4. medicated wine claimed in claim 1, it is characterized in that: the time of described immersion is 3 ~ 15 days, the percolation flow velocity is 1 ~ 10ml per minute.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013103652939A CN103417761A (en) | 2013-08-21 | 2013-08-21 | Medicinal liquor for treatment of fracture and osteoporosis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013103652939A CN103417761A (en) | 2013-08-21 | 2013-08-21 | Medicinal liquor for treatment of fracture and osteoporosis |
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| CN103417761A true CN103417761A (en) | 2013-12-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2013103652939A Pending CN103417761A (en) | 2013-08-21 | 2013-08-21 | Medicinal liquor for treatment of fracture and osteoporosis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105770864A (en) * | 2016-04-08 | 2016-07-20 | 杭州合研科技有限公司 | Composition with function of relieving joint inflammation pain |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101007117A (en) * | 2006-01-27 | 2007-08-01 | 贵州维康药业有限公司 | Application of 'Gu Kang' medicine in preparation of formulations for treating osteoarthritis and osteoporosis |
| CN102327578A (en) * | 2011-08-10 | 2012-01-25 | 栾清杨 | Preparation method for wind-expelling medicated wine |
-
2013
- 2013-08-21 CN CN2013103652939A patent/CN103417761A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101007117A (en) * | 2006-01-27 | 2007-08-01 | 贵州维康药业有限公司 | Application of 'Gu Kang' medicine in preparation of formulations for treating osteoarthritis and osteoporosis |
| CN102327578A (en) * | 2011-08-10 | 2012-01-25 | 栾清杨 | Preparation method for wind-expelling medicated wine |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105770864A (en) * | 2016-04-08 | 2016-07-20 | 杭州合研科技有限公司 | Composition with function of relieving joint inflammation pain |
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| C53 | Correction of patent of invention or patent application | ||
| CB02 | Change of applicant information |
Address after: 550002 Guizhou province Zhazuo Xiuwen County Pharmaceutical Industrial Park Applicant after: Weikang Pharmaceutical Co., Ltd., Guizhou Address before: 550002 Guizhou city of Guiyang province of China Road No. 45 Building 9 floor E block Huakun development Applicant before: Weikang Pharmaceutical Co., Ltd., Guizhou |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20131204 |