CN103417737A - Eye protection liquid with ginsenoside Rg1 - Google Patents

Eye protection liquid with ginsenoside Rg1 Download PDF

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Publication number
CN103417737A
CN103417737A CN2013103475135A CN201310347513A CN103417737A CN 103417737 A CN103417737 A CN 103417737A CN 2013103475135 A CN2013103475135 A CN 2013103475135A CN 201310347513 A CN201310347513 A CN 201310347513A CN 103417737 A CN103417737 A CN 103417737A
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China
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parts
eye
ginsenoside
eye protection
protection liquid
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Pending
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CN2013103475135A
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Chinese (zh)
Inventor
霍洪亮
王建军
彭雪微
李凤玉
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Northeast Normal University
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Northeast Normal University
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Priority to CN2013103475135A priority Critical patent/CN103417737A/en
Publication of CN103417737A publication Critical patent/CN103417737A/en
Pending legal-status Critical Current

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Abstract

The invention belongs to an eye protection health care product, and particularly relates to eye protection liquid with ginsenoside Rg1. The eye protection liquid is prepared by the following steps: a group of traditional Chinese medicine compositions including rhodiola rosea, semen cassiae, angelica sinensis, honeysuckle, wolfberry fruit, astragalus membranaceus and green tea is taken in proportion, are finely ground and mixed and are conventionally decocted and filtered to form a mixture, and then a certain amount of ginsenoside Rg1 is added to prepare the eye drops for external use. Through the effective combination, the eye protection liquid can enhance effects of resisting oxidation, resisting eye fatigue and inhibiting eye muscle spasm.

Description

A kind of eye refreshing drop that contains the ginsenoside Rg1
Technical field
The invention belongs to the eye protection health product, be specifically related to a kind of ginsenoside Rg1's of containing eye refreshing drop.
Technical background
Myopia has become one of oculopathy that in world today's scope, sickness rate is the highest.According to data, China's adolescent student, child's rate of myopia has occupied second place of the world, and pupil's rate of myopia is 28%, and junior school student's rate of myopia is 60%, and high school student's rate of myopia is 85%, and university students's rate of myopia is 90%.Bathomorphic generation and development and visual fatigue and long-term close eye have very close relationship.Teen-age eyeball is in growth and development stage, and regulating power is very strong, and the extensibility of wall of eyeball is also larger, while the near work such as reading, write, not only need the performance of the regulating action of eye, double eyeball is also cohesion, and long-term contraction of extraocular muscles produces certain pressure to eyeball like this, make increased intraocular pressure, eye inner tissue's hyperemia, add that the teenager eyeball tissue is tender and lovely, and the wall of eyeball pressurized extends gradually, the eyeball antero posterior axis is elongated, has surpassed normal value and has just formed the axial myopia eye.In addition, the long-term close eye excessively of teenager is also to cause near-sighted major reason.When looking the Distance Shortened of thing and eyes, can make eyes ciliary muscle dysregulation anxiety, long-term excess shrinkage, can not stretch ciliary muscle flexibly, affects the crystalline lens focus adjustment, forms pseudomyopia.Therefore, the generations of overwhelming majority myopia, be that over-burden due to eyes, and inner and external flesh of eyes meat is long-time in tension and can not get having a rest and be spasticity, sees like this and forms myopia at a distance with regard to feeling fuzzy.Therefore, the rapid recovery eyestrain, maintain the normal physiological function of eye muscle, is to keep the extremely important approach of eye health.
Summary of the invention
The purpose of this invention is to provide a kind of rapid recovery eyestrain, maintain the normal physiological function of eye muscle, keep eye health, eye refreshing drop of vision protection and preparation method thereof.
The present invention is on the basis of one group of Chinese medicinal components, adds the ginsenoside Rg1, and each Chinese medicine ingredients ratio and effect are as follows:
Get by weight 5 parts of Radix Rhodiolaes, 10 parts of Semen Cassiaes, 5 parts of Radix Angelicae Sinensis, 5 parts of Flos Loniceraes, 10 parts of Fructus Lycii, 5 parts of the Radixs Astragali, 5 parts of green tea.Add the ginsenoside Rg1 in above component, concentration is 2-4 mmolL -1.
Excessively with eye, causing eyes muscular fatigue is the main extraneous factor that produces myopia, except suitably having a rest, strengthens taking exercise, and notes utilizing the eye-candy eye protection of traditional Chinese medicine eye drops beyond eye hygiene, can accelerate to alleviate the eyestrain, improves eye muscle antioxidation and oxygen uptake capacity, suppresses eye muscle Ca 2+Overload, prevent spasm of ocular muscles.Ginsenoside Rg1's low concentration in the present invention is used has minimizing Ca 2+Discharge, promote NO to generate, suppress the effect of smooth muscle excess shrinkage.Radix Rhodiolae extract has defying age, anti-hypoxia, resisting fatigue and radiation resistance.Semen Cassiae has blood vessel dilating, improves the retina blood supply, eliminates vision fatigue action.Radix Angelicae Sinensis has the effect of antioxidation, promoting blood circulation to remove obstruction in the collateral.Flos Lonicerae has the effect of heat-clearing and toxic substances removing, wind-heat dissipating.Fructus Lycii has the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, antidotal effect.The Radix Astragali has the effect of anti-hypoxia, enhancing human body immunity power.Green tea is rich in tea polyphenols and has antioxidation, radiation-resistant effect.
The present invention, by the effective combination to above Chinese medicine, further adds strong anti-oxidation, the effect of resisting fatigue and inhibition spasm of ocular muscles.
The ginsenoside Rg1 is Radix Ginseng (Araliaceae herbaceos perennial Panax ginsengC. A) extract, molecular formula: C42H72O14, molecular weight: 801.01.
Radix Rhodiolae is Crassulaceae renascent herb or shrub plant Rhodiola roseaDry rhizome.
Semen Cassiae is pulse family annual herb plant Catsia tora LinnDry seed.
When being classified as the Umbelliferae herbaceos perennial Angelica sinensisDry root.
Flos Lonicerae is the perennial liana of Caprifoliaceae Lonicera JaponicaDried floral.
Fructus Lycii is plant of Solanaceae Lycium barbarum LDry mature fruit.
The Radix Astragali is leguminous plant Leguminosae dry root.
Green tea belongs to dicotyledon Camellia sinensis dried leaves.
The present invention gets Radix Rhodiolae, Semen Cassiae, Radix Angelicae Sinensis, Flos Lonicerae, Fructus Lycii, the Radix Astragali and green tea in proportion, and the conventional decoction of pulverizing mixing, filtration form mixture, add the ginsenoside Rg1, are prepared into the external eye drop.
The specific embodiment
By the following examples the present invention is further described:
Embodiment 1: the eye refreshing drop preparation
Get by weight 5 parts of Radix Rhodiolaes, 10 parts of Semen Cassiaes, 5 parts of Radix Angelicae Sinensis, 5 parts of Flos Loniceraes, 10 parts of Fructus Lycii, 5 parts of the Radixs Astragali, 5 parts of green tea.Pulverizing mixing.
Add 10 times of volume distilled water, soak 2 hours, slow fire boiling 1 hour, once filter, filtering residue continues to add 5 times of volume distilled water slow fire boiling half an hour, secondary filter, twice filtrate is merged, and it is 0.8 that filtrate is concentrated into to relative density, adds the ginsenoside Rg1 to reach 4 mmolL -1, fully mixing, cellulose acetate film filters again, and filtrate is placed in to clean high-temperature resistant container, sealing, high pressure steam sterilization sterilization (pressure: 102kPa; 125 ℃ of temperature; Time: 15 minutes).Cooling rear gnotobasis packing.
Embodiment 2: eye refreshing drop is to alleviating asthenopic effect clinical observation
Select volunteer's 20 examples in Changchun, alleviated eyestrain's observation experiment.The volunteer learns continuously, works 3 hours before computer, the eyestrain occurs, and during depending on thing far away, visual accommodation slowly waits malaise symptoms, use this eye refreshing drop 1-2 time, there are 18 volunteer's eye non fatigue feelings to feel, regulate sensation depending on thing and obviously improve, easily sensation is arranged very obviously.Look thing for 1 and regulate obviously improvement of sensation, alleviate eye fatigue and feel not obvious, 1 has obviously easily sensation, depending on thing adjusting sensation, improves not obvious.

Claims (2)

1. the preparation method of an eye refreshing drop that contains the ginsenoside Rg1, it is characterized in that concrete steps are as follows: get by weight 5 parts of Radix Rhodiolaes, 10 parts of Semen Cassiaes, 5 parts of Radix Angelicae Sinensis, 5 parts of Flos Loniceraes, 10 parts of Fructus Lycii, 5 parts of the Radixs Astragali, 5 parts of green tea, pulverizing mixing, add 10 times of volume distilled water, soak 2 hours, slow fire boiling 1 hour, once filter, filtering residue continues to add 5 times of volume distilled water, slow fire boiling half an hour, secondary filter, merge twice filtrate, it is 0.8 that filtrate is concentrated into to relative density, adds the ginsenoside Rg1 to reach 4 mmolL -1, fully mixing, cellulose acetate film filters again, and filtrate is placed in to clean high-temperature resistant container, sealing, high pressure steam sterilization sterilization, pressure: 102kPa; 125 ℃ of temperature; Time: 15 minutes, cooling rear gnotobasis packing.
2. the eye refreshing drop that contains the ginsenoside Rg1 prepared in accordance with the method for claim 1.
CN2013103475135A 2013-08-12 2013-08-12 Eye protection liquid with ginsenoside Rg1 Pending CN103417737A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103705638A (en) * 2013-12-30 2014-04-09 广西梧州制药(集团)股份有限公司 Traditional Chinese medicine composition for relieving asthenopia and preparation method thereof
CN107789617A (en) * 2017-11-16 2018-03-13 北京德尚悦目科技有限公司安徽分公司 A kind of selenium peptide improving eyesight eye refreshing drop and preparation method thereof
CN108451963A (en) * 2018-05-14 2018-08-28 孙水 A kind of eye drops for treating keratitis
CN109833357A (en) * 2017-11-29 2019-06-04 深圳市宝德生物科技有限公司 A kind of eye refreshing drop and preparation method thereof
WO2019109590A1 (en) * 2017-12-04 2019-06-13 中国药科大学 Ophthalmic drug preparation and uses thereof
CN110448618A (en) * 2018-05-07 2019-11-15 天津泰源中草药技术开发有限公司 A kind of Chinese medicine preparation and preparation method thereof for treating eyesight
CN113368012A (en) * 2021-06-10 2021-09-10 天津科技大学 Eyesight-improving nanometer eye cream containing lycium ruthenicum for adults and preparation method of eye cream
CN113384614A (en) * 2021-07-25 2021-09-14 北京阅亮科技有限公司 Preparation method of eye care solution
CN114404497A (en) * 2022-01-28 2022-04-29 福建省周嘉福生物医药有限公司 A Chinese medicinal composition with antifatigue effect

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102266445A (en) * 2011-07-22 2011-12-07 佘志坚 Eye protection Chinese medicinal composition with health care and treatment effects

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102266445A (en) * 2011-07-22 2011-12-07 佘志坚 Eye protection Chinese medicinal composition with health care and treatment effects

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
严令耕: "中医药治疗视疲劳和干眼症的研究概况", 《国医论坛》 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103705638A (en) * 2013-12-30 2014-04-09 广西梧州制药(集团)股份有限公司 Traditional Chinese medicine composition for relieving asthenopia and preparation method thereof
CN103705638B (en) * 2013-12-30 2016-05-18 广西梧州制药(集团)股份有限公司 Chinese medicine composition of a kind of alleviating asthenopia and preparation method thereof
CN107789617A (en) * 2017-11-16 2018-03-13 北京德尚悦目科技有限公司安徽分公司 A kind of selenium peptide improving eyesight eye refreshing drop and preparation method thereof
CN109833357A (en) * 2017-11-29 2019-06-04 深圳市宝德生物科技有限公司 A kind of eye refreshing drop and preparation method thereof
WO2019109590A1 (en) * 2017-12-04 2019-06-13 中国药科大学 Ophthalmic drug preparation and uses thereof
CN110448618A (en) * 2018-05-07 2019-11-15 天津泰源中草药技术开发有限公司 A kind of Chinese medicine preparation and preparation method thereof for treating eyesight
CN108451963A (en) * 2018-05-14 2018-08-28 孙水 A kind of eye drops for treating keratitis
CN113368012A (en) * 2021-06-10 2021-09-10 天津科技大学 Eyesight-improving nanometer eye cream containing lycium ruthenicum for adults and preparation method of eye cream
CN113384614A (en) * 2021-07-25 2021-09-14 北京阅亮科技有限公司 Preparation method of eye care solution
CN114404497A (en) * 2022-01-28 2022-04-29 福建省周嘉福生物医药有限公司 A Chinese medicinal composition with antifatigue effect

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Application publication date: 20131204