CN103417714A - Traditional Chinese medicine composition used for prostate diseases - Google Patents
Traditional Chinese medicine composition used for prostate diseases Download PDFInfo
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- CN103417714A CN103417714A CN2012103910809A CN201210391080A CN103417714A CN 103417714 A CN103417714 A CN 103417714A CN 2012103910809 A CN2012103910809 A CN 2012103910809A CN 201210391080 A CN201210391080 A CN 201210391080A CN 103417714 A CN103417714 A CN 103417714A
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Abstract
The invention belongs to the technical field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition used for prostate diseases. The medicine is manufactured by the following raw materials in parts by weight: 3-24 parts of rhubarb, 0.2-0.5 parts of calculus bovis, 10-30 parts of glutinous rehmannia, 3-15 parts of pangolin, 1.5-6 parts of leech, 6-10 parts of peach kernel, 10-30 parts of polygonum aviculare, 10-30 parts of fringed pink, 10-15 parts of semen plantaginis, 2-5 parts of tetrapanax papyriferus, 3-15 parts of glycyrrhiza, 3-12 parts of cassia, and 5-15 parts of Chinese angelica. The traditional Chinese medicine composition can relieve the blocking of a prostatic vessel, promote the blood supply of a pelvic cavity, improves partial blood circulation, and is good in clinical effect, safe and small in toxic side effect, and easy to be accepted by a patient when being used for curing prostatitis and benign prostatic hyperplasia.
Description
Technical field
The invention belongs to medical technical field, relate to a kind of Chinese medicine composition, particularly a kind of Chinese medicine composition for prostatosis.
Background technology
Prostatitis and prostatic hyperplasia are the common diseases of male prostate.
Prostatitis is urinary system andrology commonly encountered diseases, frequently-occurring disease, and sickness rate is high, accounts for 25%～30% of urinary system Number of Outpatients.Its clinical manifestation is various, and urinate other pathological changes of symptom, pain symptom, sexual dysfunction, psychic symptoms and secondary of mainly take are main manifestations, have a strong impact on patient's quality of life.Clinical take fall ill slowly, etiology and pathology is complicated, symptom is diversified, sign is not true to type, the course of disease delay, repeatedly show effect, prolonged difficulty is more its characteristics.The chronic prostatitis relapse rate is high, if obstinate, the patient easily brings out hyperplasia of prostate after marching toward person in middle and old age, causes dysuria, and one or two people have the anxiety of canceration.
Prostatic hyperplasia is one of common disease of male elderly patients.Along with the increase at age, the menfolk more or less has the phenomenon of prostatic hyperplasia to occur, and the old people more than 60 years old is more common.The cardinal symptom of prostatic hyperplasia has dysuria, the lighter's urine increased frequency of getting up at night, urine retention is arranged or urinated after also have a small amount of phenomenon of discharging; Severe patient occurs that the urine rheology is thin, even the phenomenon of can not arranging; Same often with symptoms such as soreness of waist lumbago, myasthenia of limbs, seminal emissions, normal and premature ejaculation occurs simultaneously, has a strong impact on patient's quality of life.
Although Therapeutic Method is more at present for chronic prostatitis and prostatic hyperplasia, as Drug therapy, psychotherapy, naturopathy (comprising transurethral microwave, the prostatic hyperthermia such as ultrasonic), massage of prostate, operative treatment etc., but treatment is long the course for the treatment of, and curative effect is undesirable, be easy to recurrence.
Therefore, good in the urgent need to a kind of clinical efficacy, safe toxic and side effects is little, and patient is easy to the medicine of accepting.
The invention provides a kind of Chinese medicine composition for prostatosis.This Chinese medicine composition has the effect of heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, blood circulation promoting and blood stasis dispelling, can remove ducts of prostate gland and block, and promotes pelvic cavity blood fortune, improves local blood circulation, fundamentally cures prostatosis.
Summary of the invention
The purpose of this invention is to provide a kind of taking convenience, effect steadily, determined curative effect, dosage form is stable and the pure Chinese medicinal preparation for prostatosis that has no side effect, to meet the demand of extensive patients.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for prostatosis, be prepared from by the raw material of Chinese medicine medicine of following weight proportion: 3～24 parts of Radix Et Rhizoma Rhei, 0.2～0.5 part of Calculus Bovis, 10～30 parts of Radix Rehmanniae, 3～15 parts of Squama Maniss, 1.5～6 parts of Hirudos, Semen Persicae 6～10 10～30 parts of Fen, Herba Polygoni Avicularis, 10～30 parts of Herba Dianthis, 10～15 parts of Semen Plantaginiss, 2～5 parts of Medulla Tetrapanaciss, 3～15 parts, Radix Glycyrrhizae, 3～12 parts of Cortex Cinnamomis, 5～15 parts of Radix Angelicae Sinensis.
Chinese medicine composition of the present invention, the weight proportion of each crude drug is preferably: 12 parts of Radix Et Rhizoma Rhei, 0.3 part of Calculus Bovis, 20 parts of Radix Rehmanniae, 9 parts of Squama Maniss, 4 parts of Hirudos, Semen Persicae 8 20 parts of Fen, Herba Polygoni Avicularis, 20 parts of Herba Dianthis, 12 parts of Semen Plantaginiss, 3.5 parts of Medulla Tetrapanaciss, 9 parts, Radix Glycyrrhizae, 8 parts of Cortex Cinnamomis, 10 parts of Radix Angelicae Sinensis.
Above composition is by weight as proportioning, when producing, can increase or reduce according to corresponding proportion, as large-scale production can be take kg as unit, or take the t(ton) be unit; Preparation also can be take g as unit on a small scale.Weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.
In Chinese medicine composition of the present invention, Radix Rehmanniae adopts Radix Rehmanniae, and Radix Glycyrrhizae adopts the Radix Glycyrrhizae uralensis better effects if.
Chinese medicine composition of the present invention, be that the raw material of Chinese medicine medical material by above-mentioned formula is formed is processed through extraction or other modes, makes pharmaceutically active substance, subsequently, take this material as raw material, add the medicine acceptable carrier while needing, make according to the routine techniques of galenic pharmacy.Described active substance can obtain by extracting respectively raw material of Chinese medicine, also can obtain by common extraction raw material of Chinese medicine medical material, also can obtain by other means, as: by pulverizing, squeeze, grind, sieve, the method such as percolation, extraction, water extraction, alcohol extraction, ester carry, chromatography obtains, these active substances can be the material of extractum form, can be that dry extract can be also fluid extract, according to the difference of preparation, need to determine to make different concentration.
Chinese medicine composition of the present invention, the pharmaceutical dosage forms of unit dose preferably, can make any pharmaceutically useful peroral dosage form when making pharmaceutical preparation, these dosage forms are selected from: watered pill, tablet, capsule, oral liquid, suck agent, granule, powder, unguentum, sublimed preparation, preferably watered pill.
Chinese medicine composition of the present invention, its pharmaceutically active substance makes through extracting processing, as processed with following methods:
Above medicine is pulverized, with the general one-tenth watered pill of powder for skinning,
Or
Above medicine, through decocting in water, obtains water extract, is condensed into cream, take this clear paste as raw material, adds the medicine acceptable carrier while needing, and according to the routine techniques of galenic pharmacy, makes.
Chinese medicine composition of the present invention, can add some medicine acceptable carriers as required, can adopt the galenic pharmacy routine techniques to prepare this pharmaceutical preparation, as pharmaceutically active substance is mixed with the medicine acceptable carrier.The acceptable carrier of described medicine is selected from: Mel, practice honey, mannitol, sorbitol, sorbic acid or potassium salt, sodium pyrosulfite, sodium sulfite, sodium thiosulfate, cysteine hydrochloride, TGA, methionine, vitamin A, vitamin C, tie up main plain E, vitamin D, azone, EDETATE SODIUM, Ethylenediaminetetraacetic Acid Calcium Salt, the alkali-metal carbonate of monovalence, acetate, phosphate or its aqueous solution, hydrochloric acid, acetic acid, sulphuric acid, phosphoric acid, aminoacid, sodium chloride, potassium chloride, sodium lactate, xylitol, maltose, glucose, fructose, dextran, glycine, starch, sucrose, lactose, mannitol, silicon derivative, cellulose and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, propylene glycol, ethanol, soil temperature 60-80, span-80, Cera Flava, lanoline, liquid paraffin, hexadecanol, gallate ester, agar, triethanolamine, basic amino acid, carbamide, allantoin, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, the B-cyclodextrin, the phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention, when making medicament, the medicament of unit dose can contain pharmaceutically active substance 0.1 ~ l000mg of the present invention, and all the other are pharmaceutically acceptable carrier.Pharmaceutically acceptable carrier can be 0. 01-99. 9% of total formulation weight amount by weight.
Instructions of taking: every day 2-3 time, each 6-9g principal agent, be 20 days a course for the treatment of.
The disease that prostatosis is " smart chamber ", physiological function is mainly spermatogenesis, store essential substances, rushes down essence, with lead to reduce to suitable.Prostate occupies the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, both logical with the water of functioning of bladder, with spermatogenesis, helps the fire of wish to be connected again, easily by damp and hot heresy, be stranded, and all damp and hot multiple abscesss, libido is out of control, and fleshliness masturbation is born essence and is felt oppressed, sitting ，Jing chamber, the stagnant smart chamber of the smart deteriorated blood stasis of blood venation block of all can disabling such as ride.Therefore its pathogenesis should be damp and hot multiple abscess, smart chamber stasis blocking, and with the passing of time the course of disease touching all because mistake is controlled, wrong treatment, and lay particular stress on stasis blocking.
Fang Zhong Herba Polygoni Avicularis inducing diuresis for treating stranguria syndrome, parasite killing, antipruritic, the Herba Dianthi inducing diuresis for treating stranguria syndrome, removing blood stasis stimulates the menstrual flow, and is principal agent altogether.Join Radix Et Rhizoma Rhei, Calculus Bovis Xiezhuo Huayu, to strengthen the power of heat clearing and damp drying, join Semen Plantaginis, the diuresis of Medulla Tetrapanacis heat clearing away dredging collateral, make heresy that outlet be arranged, drink and add the Radix Rehmanniae clearing away heat and cooling blood.Chinese angelica blood supplementing is invigorated blood circulation, Hirudo, the pain relieving of Semen Persicae blood-activating and qi-promoting.The Squama Manis detoxification sore treatment, be apt to away alter meridians, the row dissipating blood stasis stagnant.The doctor Zhang Xichun of the Qing Dynasty thinks: " its property of walking to alter is very careful.Can lead to internal organs, thorough meridians, reach the pass key thoroughly.The poly-disease of all blood clotting blood all can be opened it." what take is the sick institute that goes directly to all medicines of guiding.Take the circumstances into consideration to add low dose of Cortex Cinnamomi warming the kidney to activate YANG, conducting fire back to its origin, to make cold and cool medicine wound anxiety just, the meaning that the righting of also residing is got rid of evils.The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.All medicines share, and play altogether promoting blood circulation and stopping pain, clearing away heat-damp and promoting diuresis, the merit of inducing diuresis for treating stranguria syndrome and get effect.Be conducive to remove ducts of prostate gland and block, promote pelvic cavity blood fortune, improve local blood circulation, can fundamentally cure prostatosis.
Chinese medicine composition of the present invention is applicable to prostatitis and prostatic hyperplasia, for the course of disease with the passing of time, the patient who repeatedly shows effect, curative effect is better outstanding.
For showing the curative effect of Chinese medicine composition of the present invention, the spy provides clinical typical case history:
Lee, the man, 45 years old, before 3 years, frequent micturition, dysurea appearred, at several hospital diagnosis, be once chronic prostatitis.Through injection of antibiotic, the treatment of the methods such as urethra microwave all is not improved.Occurred over the past two years that lower abdomen dull pain, rectal tenesmus, urine were waited for, the symptoms such as nocturia increases, premature ejaculation.Have a medical check-up: the obviously increase of anus touch bilateral prostate, tenderness, matter are partially hard, and Rolandic fissure shoals, and anal sphincter is without lax.Lab testing: the conventional lecithin of prostatic fluid +++, leukocyte ++.Ultrasound diagnosis: prostate increases.Diagnosis: chronic prostatitis, prostatic hyperplasia.Take 2 courses for the treatment of of the prostatitis Chinese medicine composition watered pill of the present invention, cure, follow up a case by regular visits to not recurrence in 2 years.
Chen, man, 43 years old.Frequent micturition, urgent micturition, urinate endless, urinate wait for half a year, the perineal position discomfort, in the recent period nocturia increase, nocturia 3-4 time, once at examination in hospital, be diagnosed as prostatitis, through radio frequency, massage of prostate, hot water hip-bath etc. all without positive effect.Have a medical check-up: anus is examined the prostate II and is increased, and matter is hard, tenderness (+), disappearence of central groove, and anal sphincter is without lax.Lab testing: the conventional lecithin body of prostatic fluid +++, leukocyte ++.Ultrasound diagnosis: prostate 4.2 * 3.1 * 2.9cm, bladder residual urine 30ml.Diagnosis: chronic prostatitis, prostatic hyperplasia.Take 1 course for the treatment of of the prostatitis Chinese medicine composition watered pill of the present invention, cure, follow up a case by regular visits to not recurrence in 2 years.
Liu, man, 25 years old, driver.Frequent micturition, whitish discharge from urinary meatus, the companion saw more than perineum, scrotum section dull pain uncomfortable half a year.Sleep poor, dreaminess, the sense whole body is weak, premature ejaculation, the food of receiving is tasteless, yellowish urine muddiness, dimly red tongue greasy and thin fur, stringy and thready pulse.The prostate touch: prostate is slightly bigger than normal, tenderness, and the more tough nodosity of quality, Rolandic fissure exists.Prostatic fluid microscopy: lecithin ++, leukocyte+.Ultrasound diagnosis shows no obvious abnormalities.Take 1 course for the treatment of of the prostatitis Chinese medicine composition watered pill of the present invention, cure, follow up a case by regular visits to not recurrence in 1 year.
Zhang, man, 63 years old.Because of dysuria in first visit on April 3 in 2011.With urine thin, urine interruption, nocturia often, have every night 7～8 times more than simultaneously.Anus refers to look into: prostate two lateral lobes are thin thin, and Rolandic fissure shoals.The super prompting of B: the 8cm of the 8cm of emptying rear prostate volume 6. 1cm of bladder * 3. * 5., remaining urine amount 92ml, be diagnosed as prostatic hyperplasia (2 phase).Take 2 courses for the treatment of of the prostatitis Chinese medicine composition watered pill of the present invention, above symptom all has clear improvement; B ultrasonic prompting: after bladder is emptying, the 6cm of the 1cm of prostate volume 4. 3cm * 2. * 3., remaining urine amount 14ml.
Above example is only representative case, has above curative effect person many in addition, at this, no longer enumerates.
Criterion of therapeutical effect is with reference to " traditional Chinese medical science disease Standardization of diagnosis and curative effect ".Clinical cure: cardinal symptom and sign disappear, and examination of prostatic fluid is normal; Produce effects: cardinal symptom and sign are most of to disappear, and prostatic fluid obviously improves, and approaches normal; Effectively: cardinal symptom and sign are improved, and prostatic fluid is improved before treating, but does not reach arm's length standard; Invalid: cardinal symptom, sign and examination of prostatic fluid are all unchanged, even increase the weight of.
Through inventor statistics, according to above-mentioned criterion, in the patient in 326 20-72 of inventor's treatment year, cure 151,139 of produce effects, effective 28, invalid 8, total effective rate 97.55%.
The specific embodiment
Below in conjunction with the specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but with this, does not limit the present invention.
EXAMPLE l: the preparation of watered pill:
Prescription: Radix Et Rhizoma Rhei 12g, Calculus Bovis 0.3g, Radix Rehmanniae 20g, Squama Manis 9g, Hirudo 4g, Semen Persicae 8g, Herba Polygoni Avicularis 20g, Herba Dianthi 20g, Semen Plantaginis 12g, Medulla Tetrapanacis 3.5g, Radix Glycyrrhizae uralensis 9g, Cortex Cinnamomi 8g, Radix Angelicae Sinensis 10g.
Method for making: above medicine is ground into fine powder, crosses 80 mesh sieves, with the general one-tenth watered pill of powder for skinning, is prepared into watered pill 1000 balls.
Instructions of taking: the morning and evening one after each meal, each 6g, taking one month is a course for the treatment of.
Food prohibited: the seafood of avoiding eating anything raw or cold.
Embodiment 2
The preparation of tablet:
Prescription: Radix Et Rhizoma Rhei 24g, Calculus Bovis 0.5, Radix Rehmanniae 10g, Squama Manis 15g, Hirudo 6g, Semen Persicae 6g, Herba Polygoni Avicularis 30g, Herba Dianthi 10g, Semen Plantaginis 10g, Medulla Tetrapanacis 5g, Radix Glycyrrhizae 15g, Cortex Cinnamomi 3g, Radix Angelicae Sinensis 15g.
Method for making: upper Chinese medicine powder is broken into fine powder, with the medicine acceptable carrier, mixes, and according to the galenic pharmacy routine techniques, can be made into 1000, tablet.
Embodiment 3
The preparation of capsule:
Prescription: Radix Et Rhizoma Rhei 12g, Calculus Bovis 0.3g, Radix Rehmanniae 20g, Squama Manis 9g, Hirudo 4g, Semen Persicae 8g, Herba Polygoni Avicularis 20g, Herba Dianthi 20g, Semen Plantaginis 12g, Medulla Tetrapanacis 3.5g, Radix Glycyrrhizae uralensis 9g, Cortex Cinnamomi 8g, Radix Angelicae Sinensis 10g.
Method for making: above Chinese medicine powder is broken into fine powder, with the medicine acceptable carrier, mixes, and according to the galenic pharmacy routine techniques, can be made into 1000 of capsules.
Embodiment 4
The preparation of powder:
Prescription: Radix Et Rhizoma Rhei 3g, Calculus Bovis 0.2g, Radix Rehmanniae 30g, Squama Manis 9g, Hirudo 1.5g, Semen Persicae 10g, Herba Polygoni Avicularis 10g, Herba Dianthi 30g, Semen Plantaginis 10g, Medulla Tetrapanacis 5g, Radix Glycyrrhizae uralensis 3g, Cortex Cinnamomi 12g, Radix Angelicae Sinensis 5g.
Method for making: above Chinese medicine powder is broken into fine powder, crosses 100 mesh sieves, obtains Chinese medicine composition composition powders of the present invention.
Claims (7)
1. the Chinese medicine composition for prostatosis, be prepared from by the raw material of Chinese medicine medicine of following weight proportion: 3～24 parts of Radix Et Rhizoma Rhei, 0.2～0.5 part of Calculus Bovis, 10～30 parts of Radix Rehmanniae, 3～15 parts of Squama Maniss, 1.5～6 parts of Hirudos, 6～10 parts, Semen Persicae, 10～30 parts of Herba Polygoni Avicularis, 10～30 parts of Herba Dianthis, 10～15 parts of Semen Plantaginiss, 2～5 parts of Medulla Tetrapanaciss, 3～15 parts, Radix Glycyrrhizae, 3～12 parts of Cortex Cinnamomis, 5～15 parts of Radix Angelicae Sinensis.
2. the Chinese medicine composition for prostatosis according to claim 1; it is characterized in that, the weight proportion of each crude drug is: 12 parts of Radix Et Rhizoma Rhei, 0.3 part of Calculus Bovis, 20 parts of Radix Rehmanniae, 9 parts of Squama Maniss, 4 parts of Hirudos, Semen Persicae 8 20 parts of Fen, Herba Polygoni Avicularis, 20 parts of Herba Dianthis, 12 parts of Semen Plantaginiss, 3.5 parts of Medulla Tetrapanaciss, 9 parts, Radix Glycyrrhizae, 8 parts of Cortex Cinnamomis, 10 parts of Radix Angelicae Sinensis.
3. the Chinese medicine composition for prostatosis according to claim 1, is characterized in that, described Radix Rehmanniae is Radix Rehmanniae.
4. the Chinese medicine composition for prostatosis according to claim 1, is characterized in that, described Radix Glycyrrhizae is Radix Glycyrrhizae uralensis.
5. according to claim 1 or the 2 or 3 described Chinese medicine compositions for prostatosis, it is characterized in that, the dosage form of this Chinese medicine composition is the oral formulations form.
6. according to claim 1 or the 2 or 3 described Chinese medicine compositions for prostatosis, it is characterized in that, the dosage form of this Chinese medicine composition is the watered pill form.
7. according to claim 1 or the 2 or 3 described Chinese medicine compositions for prostatosis, it is characterized in that, the process following steps: the raw material of Chinese medicine medical material is processed through extraction or other modes, make pharmaceutically active substance, this active substance mixes with the medicine acceptable carrier, according to the galenic pharmacy routine techniques, can be made into.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106668296A (en) * | 2017-02-15 | 2017-05-17 | 四川双鑫生物科技有限公司 | Pill medicine for treating prostate diseases and preparation method of pill medicine |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1958028A (en) * | 2006-11-15 | 2007-05-09 | 王信锁 | Preparation of Chinese traditional medicine for treating hyperplasia of prostate |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1958028A (en) * | 2006-11-15 | 2007-05-09 | 王信锁 | Preparation of Chinese traditional medicine for treating hyperplasia of prostate |
Non-Patent Citations (3)
| Title |
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| 史金花等: "《偏方验方秘典》", 30 April 2008, article "《前列汤》", pages: 243 * |
| 张健: "《中医药治疗慢性前列腺炎现状》", 《河北中医》, vol. 32, no. 3, 31 March 2010 (2010-03-31), pages 464 - 466 * |
| 马莉萍: "《名老中医治疗良性前列腺增生经验荟萃》", 《中国临床医生》, vol. 34, no. 4, 31 December 2006 (2006-12-31), pages 57 - 59 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106668296A (en) * | 2017-02-15 | 2017-05-17 | 四川双鑫生物科技有限公司 | Pill medicine for treating prostate diseases and preparation method of pill medicine |
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