CN103416663A - Whole-grain complete-nutrition formulation food for diabetics - Google Patents
Whole-grain complete-nutrition formulation food for diabetics Download PDFInfo
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Abstract
The invention discloses whole-grain complete-nutrition formulation food for diabetics, and relates to the field of health-care food. The whole-grain complete-nutrition formulation food for the diabetics comprises oat bran powder, oat powder, pearl barley powder, chromium-enriched yeast powder, traditional Chinese medicine water extracting solutions, stevioside, edible essence and microelement, wherein the traditional Chinese medicine water extracting solutions comprise the water extract of Chinese yam, the water extract of astragalus, the water extract of anemarrhena asphodeloides, the water extract of Chinese magnoliavine fruits, the water extract of radix codonopsis, the water extract of radix puerariae, the water extract of lychee seeds and the water extract of radix ophiopogonis, and the microelement is appropriately added by control over the content of magnesium, the content of potassium, the content of manganese, the content of chlorine and the content of inositol in a finished product. According to the whole-grain complete-nutrition formulation food for the diabetics, the microelement and dietary fiber are enriched to meet the requirement of the diabetics for special nutrition; due to the fact that the traditional Chinese medicine components are added, the obvious effect of reducing the blood glucose index and the obvious effect of relieving complications of the diabetes can be achieved, and the whole-grain complete-nutrition formulation food for the diabetics can serve as nutritious food of the diabetics and health care products for adjuvant therapy of the diabetics.
Description
Technical field
The present invention relates to the health food technology field, particularly relate to a kind of full nutrient formulation food of diabetes patients.
Background technology
Diabetes are a kind of due to due to defect of insulin secretion and/or insulin action obstacle, the metabolic disease that the hyperglycaemia of take is feature.Continue hyperglycaemia and long-term metabolic disorder etc. and can cause body tissue's organ, particularly eye, kidney, cardiovascular and neural infringement and dysfunction and exhaustion.Severe patient can cause acute complications DKA and the Hyperosmotic comas such as dehydration, electrolyte disturbance and acid-base imbalance.Over nearly 30 years, China's diabetes prevalence significantly increases.National 14 300,000 people's of provinces and cities in 1980 epidemiologic data demonstration, the illness rate of diabetes is 0.7%.2007-2008 years, under diabetology branch of Chinese Medical Association tissue, 14 provinces and cities in the whole nation carried out the epidemiology survey of diabetes.Result shows that the adult diabetes prevalence of China more than 20 years old is 9.7%.
The treatment of diabetes comprises the detection of diabetes education, dietary therapy, exercise therapy, drug therapy, blood sugar monitoring and other angiocardiopathy risk factors and controls several aspects.
Dietary therapy is the primary measure of all kinds diabetes Primary Care.The principle of dietary therapy is: control total amount of heat and body weight.Reduce fat, especially saturated fatty acid content in food, increase food fiber content, make the proportion of carbohydrate in food, fat and protein reasonable.Control the absorption of meals gross energy, rationally the various nutriments of balanced distribution.Maintain reasonable body weight, the target that overweight/obesity patient reduces body weight is the 5%-10% that lost weight during 3-6 month.The patient that becomes thin should recover and the long term maintenance ideal body weight by balanced Nutrition Project.
The practice of several thousand of China people process, accumulated abundant medicinal knowledge, the utilization of some Chinese medicines of occurring in nature obtained especially to approval and the high praise of modern medicine.Chinese medicine has self advantageous advantage in treatment some chronic diseases, difficult and complicated cases, and it often has that side effect is little, reinvigoration, the advantage such as treat both principal and secondary aspect of disease, and is subject to domestic and international doctor's favor.Food therapy is all the indispensable approach that health is cured the disease since ancient times, under the promotion of modern industry and technology, food therapy is further developed, the nutrient and healthcare products of Chinese medicine compound prescription have just arisen at the historic moment, this health food is being brought into play huge effect in the process of prevention and treatment disease, also by modern doctor and patient, is accepted gradually.
The full nutrient formulation food of the five cereals of a kind of diabetes patients provided by the present invention, just the food of the advantage of Chinese herbal treatment diabetes and full nutrient formulation is combined, traditional Chinese medicine ingredients and enriched nutritive composition are acted synergistically, making a kind ofly can provide the nutritional labelings such as the needed dietary fiber of diabetic, trace element, the nutrient and healthcare products that can play a role to treatment and the prevention of diabetes again.
Summary of the invention
The objective of the invention is the demand to the food nutrition element for the diabetic, the optimization traditional Chinese medicine prescription of curing diabetic with combined, that traditional Chinese medicine ingredients and nutrient act synergistically, make a kind of both can meet diabetic's nutritional need, adaptation diabetic's food feature, the health food that can play better effects to prevention and the treatment of diabetes is arranged.
For reaching above purpose, it is primary raw material that oat bran powder, oatmeal, coixlacrymajobi powder are take in the present invention, adds Cr-enriched yeast powder, Chinese medicine aqueous extract, steviol glycoside, flavoring essence, trace element and is mixed.
The full nutrient formulation food of the five cereals of a kind of diabetes patients provided by the present invention, the proportioning of its various raw materials is: oat bran powder 20-35 weight portion, oatmeal 8-12 weight portion, coixlacrymajobi powder 10-15 weight portion, Cr-enriched yeast powder 0.2-0.4 weight portion, Chinese medicine aqueous extract 4-8 weight portion, steviol glycoside 0.1-0.3 weight portion, flavoring essence 0.01-0.015 weight portion, trace element add makes finished product meet mass percent.Optimal proportion is: oat bran powder 28 weight portions, oatmeal 10 weight portions, coixlacrymajobi powder 13 weight portions, Cr-enriched yeast powder 0.3 weight portion, Chinese medicine aqueous extract 6 weight portions, steviol glycoside 0.2 weight portion, flavoring essence 0.01 weight portion, trace element add makes finished product meet mass percent.
Wherein the Chinese prescription of Chinese medicine aqueous extract is: fruit of Chinese magnoliavine 12-28 weight portion, wind-weed 12-28 weight portion, Chinese yam 35-65 weight portion, Radix Codonopsis 8-12 weight portion, root of kudzu vine 26-36 weight portion, Radix Astragali 18-38 weight portion, semen litchi 4-7 weight portion, the tuber of dwarf lilyturf 9-13 weight portion.Optimum Chinese medicine preparation is: the fruit of Chinese magnoliavine 20 weight portions, the wind-weed 20 weight portions, Chinese yam 50 weight portions, Radix Codonopsis 10 weight portions, the root of kudzu vine 30 weight portions, the Radix Astragali 28 weight portions, semen litchi 5 weight portions, the tubers of dwarf lilyturf 11 weight portion.
The interpolation of trace element is according to the micro-control criterion of finished product, and this control criterion is: magnesium 0.1-0.3%, potassium 0.6-0.9%, manganese 0.002-0.004%, chlorine 0.6-0.9%, inositol 0.1-0.2%.
The processing technology of food of the present invention is:
Nutraceutical of the present invention, can make powdery or graininess, with warm water, dissolves and take, and also can make the block foods such as biscuit, shortcake, directly edible.
The primary raw material of the full nutrient formulation food of the five cereals of a kind of diabetes patients provided by the present invention is:
The oat bran powder: oat bran is that the shell of oat contains abundant fiber and other nutritional labelings, comprising: iron, potassium and vitamin B1.Not containing cholesterol, with a small amount of fat of full cereals.Be rich in dietary fiber.Used oat chaff powder of the present invention is through fine gtinding by high-quality oat bran.Wherein dietary fiber is called " the 7th nutrient " by nutrition educational circles, U.S. FDA suggestion in 1998, supplement appropriate dietary fiber effectively prevention of obesity, diabetes, coronary heart disease, the carcinoma of the rectum, colon cancer etc., dietary fiber, by absorbing the moisture in stomach and intestine, expands rapidly, makes human body produce satiety, and reduce intestinal absorption carbohydrate, lipid material, lubricated enteron aisle, promote defecation, suppresses fat.
Main Function
1. the promotion intestines peristalsis, soften stool, Constipation, colon cancer and the carcinoma of the rectum
2. cholesterol, the triglycerides in reduction blood, be beneficial to fat control
3. the removing vivotoxin, prevent the skin problems such as color spot formation, whelk
4. reduce the absorption of carbohydrate in enteron aisle, reduce postprandial blood sugar
5. promote intestinal beneficial bacterium propagation, improve the absorption of human body ability.
Suitable crowd
1. dry and hard excrement, habitual constipation, abdominal distension, indigestion, overweight people
2. cardiovascular and cerebrovascular disease is as hypertension, high fat of blood, artery sclerosis, calculus etc.
3. the unstable person of diabetes personage, particularly postprandial blood sugar
4. color spot is calm, face is dark yellow, long acne person.
It is helpful to diabetic's dietary therapy that food of the present invention is rich in dietary fiber.
Oatmeal: oat has another name called bromegrass, wild wheat.The medical value of oat and health-care effect, generally acknowledged by medical circle of all times.Reduce blood pressure, reduce cholesterol, control colorectal cancer, control heart disease.Take turns animal experiment and 3 according to 18 medical institutions 5 such as 1981～1985 years the Chinese Academy of Agricultural Sciences and cardiovascular and cerebrovascular research center, Beijing, Haidian, Beijing hospital and take turns 997 routine clinical observations and studies have shown that, naked oats can prevent and treat the cardiovascular and cerebrovascular disease caused by high fat of blood.Take the naked oats sheet 3 months (day take 100 grams), can obviously reduce cholesterol, triglyceride, beta lipoprotein in cardiovascular and liver, total effective rate reaches 87.2%, and its curative effect and coronary heart disease is without significant difference, and has no side effect.For because of liver, nephropathy, diabetes, the Secondary Hyperlipidemia that fatty liver etc. cause also has same significantly curative effect.Long-term edible oatmeal, be conducive to the control of diabetes and obesity.Used oat powder of the present invention is to be ground and made by good oat whole wheat.
Coixlacrymajobi powder: the nutritive value of the seed of Job's tears is very high, is described as " king of world grass ".The seed of Job's tears can be used as grain and eats, and taste is similar with rice, and absorption easy to digest, cooks congee, does Tang Junke.Because the seed of Job's tears is nutritious, for weakness due to chronic disease, reconvalescent after being ill, old man, puerpera, children are reasonable medicinal foods, can often take.No matter for nourishing or for curing the disease, effect is comparatively mitigation all, is slightly cold and does not injure one's stomach, beneficial spleen and do not grow greasy.It is reported, the composition coixenolide that the seed of Job's tears is cured the disease, not only have tonic effect, but also be a kind of anticancer, can suppress ehrlich ascites cell, can be used for cancer of the stomach and cervix cancer.Contained seed of Job's tears alcohol in the root of the seed of Job's tears, except the effect with above-mentioned coixenolide, also have the effect of step-down, diuresis, analgesic and ascarifuge, is applicable to hypertension, lithangiuria, urinary tract infections, roundworm disease etc.The present invention's coixlacrymajobi powder used is to be formed by high-quality seed of Job's tears fine grinding.
The Cr-enriched yeast powder:
Chromium is one of trace element essential in human body, and it plays a crucial role maintaining aspect health.The trace element that chromium is very favourable to human body, should be not out in the cold, and it is the important element that blood sugar is grown and regulated to normal growth.Chromium plays an important role in all insulin adjusting activities as a kind of micronutrient element of necessity, and it can help insulin to promote that glucose enters intracellular efficiency, is important blood sugar regulator.Aspect blood glucose-control, particularly the diabetic is had to important effect.Chromium or the constituent of GTF, it can promote that insulin plays a role in vivo fully.On physiology, concerning the growing of body, insulin and growth hormone are of equal importance, indispensable.The effect of insulin in human body is very large, is picked-up, storage and utilization that in body, important synthetic hormone can promote glucose, can promote again the synthetic of aliphatic acid, can also promote the synthetic of protein and store.There is the problem that lacks chromium in the diabetes patient, and when complication is arranged patient's chromium content significantly lower than without the complication patient.The chromium element that supplementary needed by human body is wanted is the safest, effective method is to adopt GTF chromium, and yeast chromium is safest at present.
Cr-enriched yeast is a kind of a kind of functional form saccharomycete that can the enrichment Organic Chromium that utilizes saccharomycete exploitation.It can produce yeast chromium.
The main function of Cr-enriched yeast
Strengthen insulin active, control blood sugar.Can regulate the fat stores amount, help loss of weight.Reduce the content of blood cholesterol and triglycerides, the prevention cardiovascular disease.
1. reduce diabetic's blood sugar, also can improve its hypoglycemic reaction, there is the dual regulation effect to blood sugar, can effectively control diabetes, eliminate the anomaly of glucose tolerance aspect.
2. can obviously fall the Zhi serum cholesterol level, alleviate the artery sclerosis symptom.
3. can correct the IGT that lacks chromium children and long-term parenteral patient.
4. can effectively increase the human muscle, reduce fat.
Many advantages such as in addition, Cr-enriched yeast also has edible safety, nontoxicity, the human body utilization rate is high, nutritious, production cost is low.
Cr-enriched yeast powder used in the present invention is the food stage finished product, and chromium content is more than 2000mg/kg.
The Chinese medicine aqueous extract:
Chinese medicine aqueous extract used in the present invention is, by formula, takes the Chinese medicine of respectively distinguishing the flavor of, and pulverizes respectively the purified water that adds 10 times, decocts 2 hours, and a filters to get filtrate; Filter residue is added to the water of 5 times, continue to decoct 2 hours, the b that filters to get filtrate, mix a and b, is the Chinese medicine aqueous extract.Wherein respectively distinguish the flavor of Chinese medicine respectively:
The fruit of Chinese magnoliavine: property acid, sweet, temperature.Return lung, the heart, kidney channel.There is convergence astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, the effect of kidney calming.For the void of coughing for a long time, breathe heavily, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the feeble pulse of losing heart, interior heat is quenched one's thirst, palpitation and insomnia.
The wind-weed: property is bitter, sweet, cold.Return lung, stomach, kidney channel.There is clearing heat-fire, the effect of promoting the production of body fluid and moisturizing.For fever caused by exogenous pathogenic factors, high hot polydipsia, lung-heat type cough, osteopyrexia and fever, interior heat is quenched one's thirst, the dry constipation of intestines.
Chinese yam: return spleen, lung, kidney channel.There is the tonifying spleen nourishing the stomach, the beneficial lung that promotes the production of body fluid, the effect of the puckery essence of kidney tonifying.Few for insufficiency of the spleen food, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, under band, frequent micturition, abnormal heat is quenched one's thirst.
Radix Codonopsis: property is sweet, flat.Return spleen, lung channel.There is tonifying middle-Jiao and Qi, the effect of invigorating the spleen benefit lung.For a little less than the spleen deficiency syndrome of the lung, the palpitaition of breathing hard, anorexia and loose stool, void is breathed with cough and is coughed, and interior heat is quenched one's thirst.
The root of kudzu vine: property is sweet, hot, cool.Return spleen, stomach warp.Have relieving muscles to expel heat, promote the production of body fluid, promoting eruption, rise the effect of positive antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hot dysentery, have loose bowels; The hypertension neck pain.
The Radix Astragali: property is sweet, temperature.Return lung, the spleen channel.There is invigorating qi for strengthening superficies, diuresis holder poison, apocenosis, the effect of expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, the uterine bleeding of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult bursts, and burst and do not hold back for a long time, the flaccidity of limbs due to deficiency of blood Huang, interior heat is quenched one's thirst; The chronic nephritis albuminuria, diabetes.
Semen litchi: sweet, the micro-hardship of property, temperature.Return liver, kidney channel.Promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.For cold hernia stomachache, testiclar gall.
The tuber of dwarf lilyturf: sweet, the micro-hardship of property is slightly cold.The thoughts of returning home, lung, stomach warp.There is nourishing Yin and promoting production of body fluid, the effect that moistening lung clears away heart-fire.For dryness of the lung dry cough, cough due to consumptive disease, Tianjin wound is thirsty, vexed insomnia, the dry constipation of intestines.
Chinese medicine extract prescription used in the present invention is allotment and fixed meticulously on the basis of summing up clinical experience and traditional proved recipe, from clinical testing, adding of traditional Chinese medicine ingredients, can form synergy with nutritional labeling, there is the enhancing islet function, promote sugared utilization, improve glycometabolic effect.And can strengthen the result for the treatment of of chemicals, reach the purpose of prevention and complication.
Steviol glycoside:
Stevioside (being commonly called as stevioside, steviol glycoside) is a kind of new type natural sweetener that essence is carried from catananche's STEVIA REBAUDIANA (or claiming stevia rebaudian leaf).The data demonstration of international sweetener industry, stevioside is widely used in the production of food, beverage, flavoring in Asia, North America, South America and EU countries.For making low-calorie diet, beverage, be highly suitable for diabetes, obesity, arteriosclerotic edible.
Trace element:
Food of the present invention is only controlled the content of magnesium in trace element, potassium, manganese, chlorine and inositol.
Wherein, magnesium, as the activator of enzyme, participates in the enzymatic reaction more than 300 kinds.Synthetic, the nucleic acid metabolism of glycolysis, fatty acid oxidation, protein etc. needs magnesium ion to participate in.Generally can add magnesium sulfate in food and carry out the strengthen magnesium element
Potassium involved in sugar, protein and energetic supersession: during glyconeogenesis, need potassium together to enter with it cell, when glycogen decomposes, potassium disengages again in cell.Generally can add potassium phosphate, potash etc. in food and strengthen potassium element.
Manganese can maintain normal glycometabolism and fat metabolism.Can improve the hematopoiesis function of body.
Chlorine maintains the body fluid acid-base balance.Participate in the transportation of blood CO divalent ion.In food, the general calcium chloride that adds is strengthened the chlorine element.
Inositol has effect, the reduction cholesterol of fat metabolism and cholesterol, helps the prevention of arterial sclerosis.Help to remove the effects such as fat of liver.
These several trace elements be all glycolysis, glycometabolism, glycogen synthetic, regulate the necessary trace element of blood balance, supplementing of these trace elements, can play effect balanced in nutrition, as to alleviate complication and ancillary drug treatment.
Compared with prior art, the full nutrient formulation food of the five cereals of a kind of diabetes patients provided by the invention has following characteristics and significantly technological progress:
1, the present invention has strengthened with the trace element headed by chromium and dietary fiber, and by groping formula, trace element and the dietary fiber of strengthening can be acted synergistically with base nutrients matter, reached micro-and dietary fiber utilization rate increase, effective.Therefore, this food not only can meet diabetic's nutritional need, can also play crucial regulating action to patient's glycometabolism, blood balance etc., can reach on the one hand the purpose of dietary therapy, can improve on the other hand patient's physique, the harm that alleviates complication.
2, the present invention has added Chinese medicine extract on the basis of basic nutrition, through formula, gropes to make traditional Chinese medicine ingredients and various nutrient that best synergy occurs, and obtains good result for the treatment of, the analysis result of concrete visible embodiment 7.
3, the without any side effects and harm of food provided by the present invention, mouthfeel is good, and instant edible singly not can be used as the aid nutrition product in when treatment, can also eat for a long time as the health products that the colony of suffering from the diabetes potential risk be arranged.
The specific embodiment
Form is described in further detail foregoing of the present invention again by the following examples, but this should be interpreted as to the scope of the above-mentioned theme of the present invention only limits to following embodiment, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
Embodiment mono-: the preparation of full formula nutrient powder
1, respectively by oat bran, oat, the seed of Job's tears, clean, dry, ground 80 mesh sieves, standby;
2, by formula, take respectively: fruit of Chinese magnoliavine 1200g, wind-weed 1200g, Chinese yam 3500g, Radix Codonopsis 800g, root of kudzu vine 2600g, Radix Astragali 1800g, semen litchi 400g, the tuber of dwarf lilyturf 900g.Pulverize respectively, mix, add the purified water of 10 times of weight, reflux and decoct 2 hours, a filters to get filtrate; The purified water that adds 5 times of weight in filter residue, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, be the Chinese medicine aqueous extract, standby;
3, take respectively oat bran powder 20kg, oatmeal 8kg, coixlacrymajobi powder 10kg, Cr-enriched yeast powder 0.2kg, Chinese medicine aqueous extract 4kg, steviol glycoside 0.1kg, flavoring essence 0.01kg, add purified water and be mixed into scattered paste shape, mixture is heated to 100 ℃, keeps 5 minutes, cooling;
4, sample thief detects trace element, takes the circumstances into consideration to add trace element is controlled by standard: magnesium 0.1-0.3%, potassium 0.6-0.9%, manganese 0.002-0.004%, chlorine 0.6-0.9%, inositol 0.1-0.2%;
5, will mix pastel and dry under 80 ℃, grind, cross 60 mesh sieves, press every bag of encapsulation of 30-50g, be finished product.
Embodiment bis-: the preparation of full formula nutrient powder
1, respectively by oat bran, oat, the seed of Job's tears, clean, dry, ground 80 mesh sieves, standby;
2, by formula, take respectively: fruit of Chinese magnoliavine 2800g, wind-weed 2800g, Chinese yam 6500g, Radix Codonopsis 1200g, root of kudzu vine 3600g, Radix Astragali 3800g, semen litchi 700g, the tuber of dwarf lilyturf 1300g.Pulverize respectively, mix, add the purified water of 10 times of weight, reflux and decoct 2 hours, a filters to get filtrate; The purified water that adds 5 times of weight in filter residue, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, be the Chinese medicine aqueous extract, standby;
3, take respectively oat bran powder 35kg, oatmeal 12kg, coixlacrymajobi powder 15kg, Cr-enriched yeast powder 0.4kg, Chinese medicine aqueous extract 8kg, steviol glycoside 0.3kg, flavoring essence 0.015kg, add purified water to be mixed into scattered paste shape, mixture is heated to 100 ℃, keeps 5 minutes, cooling;
4, sample thief detects trace element, takes the circumstances into consideration to add trace element is controlled by standard: magnesium 0.1-0.3%, potassium 0.6-0.9%, manganese 0.002-0.004%, chlorine 0.6-0.9%, inositol 0.1-0.2%;
5, will mix pastel and dry under 80 ℃, grind, cross 60 mesh sieves, press every bag of encapsulation of 30-50g, be finished product.
Embodiment tri-: the preparation of full formula nutrient powder
1, respectively by oat bran, oat, the seed of Job's tears, clean, dry, ground 80 mesh sieves, standby;
2, by formula, take respectively: fruit of Chinese magnoliavine 1900g, wind-weed 1900g, Chinese yam 4500g, Radix Codonopsis 850g, root of kudzu vine 2900g, Radix Astragali 2100g, semen litchi 550g, the tuber of dwarf lilyturf 1100g.Pulverize respectively, mix, add the purified water of 10 times of weight, reflux and decoct 2 hours, a filters to get filtrate; The purified water that adds 5 times of weight in filter residue, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, be the Chinese medicine aqueous extract, standby;
3, take respectively oat bran powder 25kg, oatmeal 9kg, coixlacrymajobi powder 13kg, Cr-enriched yeast powder 0.35kg, Chinese medicine aqueous extract 7kg, steviol glycoside 0.25kg, flavoring essence 0.014kg, add purified water and be mixed into scattered paste shape, mixture is heated to 100 ℃, keeps 5 minutes, cooling;
4, sample thief detects trace element, takes the circumstances into consideration to add trace element is controlled by standard: magnesium 0.1-0.3%, potassium 0.6-0.9%, manganese 0.002-0.004%, chlorine 0.6-0.9%, inositol 0.1-0.2%;
5, will mix pastel and dry under 80 ℃, grind, cross 60 mesh sieves, press every bag of encapsulation of 30-50g, be finished product.
Embodiment tetra-: the preparation of full formula nutrient powder
1, respectively by oat bran, oat, the seed of Job's tears, clean, dry, ground 80 mesh sieves, standby;
2, by formula, take respectively: fruit of Chinese magnoliavine 2200g, wind-weed 2300g, Chinese yam 5600g, Radix Codonopsis 1150g, root of kudzu vine 3200g, Radix Astragali 2100g, semen litchi 650g, the tuber of dwarf lilyturf 1100g.Pulverize respectively, mix, add the purified water of 10 times of weight, reflux and decoct 2 hours, a filters to get filtrate; The purified water that adds 5 times of weight in filter residue, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, be the Chinese medicine aqueous extract, standby;
3, take respectively oat bran powder 33kg, oatmeal 11kg, coixlacrymajobi powder 14kg, Cr-enriched yeast powder 0.3kg, Chinese medicine aqueous extract 6kg, steviol glycoside 0.2kg, flavoring essence 0.014kg, add purified water and be mixed into scattered paste shape, mixture is heated to 100 ℃, keeps 5 minutes, cooling;
4, sample thief detects trace element, takes the circumstances into consideration to add trace element is controlled by standard: magnesium 0.1-0.3%, potassium 0.6-0.9%, manganese 0.002-0.004%, chlorine 0.6-0.9%, inositol 0.1-0.2%;
5, will mix pastel and dry under 80 ℃, grind, cross 60 mesh sieves, press every bag of encapsulation of 30-50g, be finished product.
Embodiment five: the preparation of full formula nutrient powder
1, respectively by oat bran, oat, the seed of Job's tears, clean, dry, ground 80 mesh sieves, standby;
2, by formula, take respectively: fruit of Chinese magnoliavine 2000g, wind-weed 2000g, Chinese yam 5000g, Radix Codonopsis 1000g, root of kudzu vine 3000g, Radix Astragali 2800g, semen litchi 500g, the tuber of dwarf lilyturf 1100g.Pulverize respectively, mix, add the purified water of 10 times of weight, reflux and decoct 2 hours, a filters to get filtrate; The purified water that adds 5 times of weight in filter residue, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, be the Chinese medicine aqueous extract, standby;
3, take respectively oat bran powder 28kg, oatmeal 10kg, coixlacrymajobi powder 13kg, Cr-enriched yeast powder 0.3kg, Chinese medicine aqueous extract 6kg, steviol glycoside 0.2kg, flavoring essence 0.01kg, add purified water, be mixed into scattered paste shape, mixture is heated to 100 ℃, keep 5 minutes, cooling;
4, sample thief detects trace element, takes the circumstances into consideration to add trace element is controlled by standard: magnesium 0.1-0.3%, potassium 0.6-0.9%, manganese 0.002-0.004%, chlorine 0.6-0.9%, inositol 0.1-0.2%;
5, will mix pastel and dry under 80 ℃, grind, cross 60 mesh sieves, press every bag of encapsulation of 40g, be finished product.
Embodiment six: do not add the preparation of the nutrient powder of Chinese medicine aqueous extract
1, respectively by oat bran, oat, the seed of Job's tears, clean, dry, ground 80 mesh sieves, standby;
2, take respectively oat bran powder 28kg, oatmeal 10kg, coixlacrymajobi powder 13kg, Cr-enriched yeast powder 0.3kg, steviol glycoside 0.2kg, flavoring essence 0.01kg, add purified water, be mixed into scattered paste shape, mixture is heated to 100 ℃, keep 5 minutes, cooling;
3, sample thief detects trace element, takes the circumstances into consideration to add trace element is controlled by standard: magnesium 0.1-0.3%, potassium 0.6-0.9%, manganese 0.002-0.004%, chlorine 0.6-0.9%, inositol 0.1-0.2%;
4, will mix pastel and dry under 80 ℃, grind, cross 60 mesh sieves, press every bag of encapsulation of 40g, be finished product.
For clinical testing.
Embodiment seven: the clinical trial of nutrient powder of the present invention
Clinical testing is divided into two parts, and a part is the experiment of animal acute toxicity and chronic toxicity; Another part is diabetic's clinical testing.
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 5 and embodiment 6 gained nutrient powder.
Experimental animal: regular grade NIH mouse, body weight 18g ± 2g, male and female half and half.
Method and result:
By two kinds of each 40g of nutrient powder, be modulated into pasty state by the 160ml warm water respectively;
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 5 and embodiment 6 gained nutrient powder.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration of two kinds of nutrient powder: be divided into high, medium and low three dosage groups, be respectively 200,100,50 times of edible for patients amount, be mixed into pasty state with warm water 1:1 respectively;
By above two toxicity tests, prove that the nutrient powder that the present invention makes by embodiment 5 and embodiment 6 is safe, have no side effect, can be used for clinical patients is carried out to clinical testing.
(2) diabetic's clinical testing
1, clinical data
Year July in May, 2013 to 2013, choose altogether 150 routine diabetics for treatment target, male 75 people wherein, female 75 people, average 57.5 years old, be divided into A, B, tri-groups of C, every group of 50 people at random.Shape person 36 people that wherein developed complications, every group of Random assignment 12 people.
2., methods for the treatment of
The A group: the injection insulin glargine, 1 times/day, each one, as reference group;
B group: injection insulin glargine, 1 times/day, each one; Take in addition the nutrient powder made by the described method of embodiment 5, three times on the one, each 40g.
C group: injection insulin glargine, 1 times/day, each one; Take in addition the nutrient powder (do not add Chinese medicine extract, all the other formulas are constant) that the described method of the embodiment of the present invention 6 makes.
All patient's drug administrations 30 days medicine of stopping using afterwards, B, C group continue to take nutrient powder, after 30 days, observe again.
3, efficacy assessment standard
(1), at injectable drug before 1 day, after injectable drug the 30th day and injectable drug the 60th day, to every group, detect respectively the fasting blood-glucose index; All indexs are used
Mean, the statistical method of application t check is analyzed result, and P<0.05 thinks to have remarkable meaning.
(2) Observation patient's situation.
4. treatment results is as follows:
(1) comparison (mmol/L) of blood sugar before and after three groups of patient's drug administrations of table 1
Remarks: with test A, C group, compare * p<0.05.
(2) situation of Observation, A, B, tri-group complication patients' of C situation all takes a turn for the better, but the B group takes a turn for the better more obvious, the patient of the concurrent symptom of becoming thin particularly, but C group patient is better than the A group is poorer than the B group, B group recovery situation is significantly better than A group and C group, and patient's complexion is better, and health is better.
After medication, the patient's of 3 groups blood sugar all obviously reduces as can be seen from Table 1, and B group blood sugar falls minimumly, and effect is best, and the C group is taken second place; In drug withdrawal, after 30 days, 3 group blood sugar all rebound to some extent, but the bounce-back of B group blood sugar is minimum, and the C group is taken second place.From the result of Observation, can find out, B group Nutritional Status of Patients and the best C group of condition are taken second place, and the A group is the poorest.These presentation of results, wholefood of the present invention also has certain auxiliary therapeutic action to diabetes when not adding traditional Chinese medicine ingredients, the synergy that this gives the credit to trace element, the dietary fiber of strengthening and sends nutrient; After having added traditional Chinese medicine ingredients again, the trace element of traditional Chinese medicine ingredients, nutritional labeling and strengthening complements each other, and has obtained the effect better to the diabetes auxiliary curing.And recovery, maintenance blood glucose balance for patient's daily health caring, complication have good effect.
To sum up, the full nutrient formulation food of the five cereals of a kind of diabetes patients disclosed by the invention, safe, without any side effects, and recover, keep blood glucose balance, daily health caring etc. that good effect is arranged to auxiliary curing, the complication of diabetes.
Claims (9)
1. the full nutrient formulation food of the five cereals of a diabetes patients is characterized in that: take oat bran powder, oatmeal, coixlacrymajobi powder is raw material, adds Cr-enriched yeast powder, Chinese medicine aqueous extract, steviol glycoside, flavoring essence, trace element and is mixed.
2. the full nutrient formulation food of the five cereals of a kind of diabetes patients as claimed in claim 1, it is characterized in that: the proportioning of described raw material is: oat bran powder 20-35 weight portion, oatmeal 8-12 weight portion, coixlacrymajobi powder 10-15 weight portion, Cr-enriched yeast powder 0.2-0.4 weight portion, Chinese medicine aqueous extract 4-8 weight portion, steviol glycoside 0.1-0.3 weight portion, flavoring essence 0.01-0.015 weight portion.
3. the full nutrient formulation food of the five cereals of a kind of diabetes patients as claimed in claim 1, it is characterized in that: the proportioning of described raw material is: oat bran powder 28 weight portions, oatmeal 10 weight portions, coixlacrymajobi powder 13 weight portions, Cr-enriched yeast powder 0.3 weight portion, Chinese medicine aqueous extract 6 weight portions, steviol glycoside 0.2 weight portion, flavoring essence 0.01 weight portion.
4. the full nutrient formulation food of the five cereals of a kind of diabetes patients as claimed in claim 1, it is characterized in that: the Chinese medicine preparation of described Chinese medicine aqueous extract is: fruit of Chinese magnoliavine 12-28 weight portion, wind-weed 12-28 weight portion, Chinese yam 35-65 weight portion, Radix Codonopsis 8-12 weight portion, root of kudzu vine 26-36 weight portion, Radix Astragali 18-38 weight portion, semen litchi 4-7 weight portion, the tuber of dwarf lilyturf 9-13 weight portion.
5. the full nutrient formulation food of the five cereals of a kind of diabetes patients as claimed in claim 1, it is characterized in that: the Chinese medicine preparation of described Chinese medicine aqueous extract is: the fruit of Chinese magnoliavine 20 weight portions, the wind-weed 20 weight portions, Chinese yam 50 weight portions, Radix Codonopsis 10 weight portions, the root of kudzu vine 30 weight portions, the Radix Astragali 28 weight portions, semen litchi 5 weight portions, the tubers of dwarf lilyturf 11 weight portion.
6. the full nutrient formulation food of the five cereals of a kind of diabetes patients as claimed in claim 1, it is characterized in that: described micro-mass percentage content is: magnesium 0.1-0.3%, potassium 0.6-0.9%, manganese 0.002-0.004%, chlorine 0.6-0.9%, inositol 0.1-0.2%.
7. the full nutrient formulation food of the five cereals of a kind of diabetes patients as claimed in claim 1, it is characterized in that: the processing technology of described food is:
8. the full nutrient formulation food of the five cereals of a kind of diabetes patients as claimed in claim 1, it is characterized in that: described food can be made powdery, graininess or block food.
9. the full nutrient formulation food of the five cereals of a kind of diabetes patients as claimed in claim 1 is characterized in that: described food can be used as the nutriment of adjuvant therapy of diabetes or can be used as the health products of prevention diabetes.
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| GR1008915B (en) * | 2015-07-31 | 2016-12-23 | Elbisco Ανωνυμη Βιομηχανικη & Εμπορικη Εταιρια Τροφιμων | Preparation of wheat-based bread by addition of non-active yeast enriched with trivalent chromium |
| CN107375784A (en) * | 2017-08-15 | 2017-11-24 | 晁伟岩 | It is capable of the preparation method of the oat mixed powder of three high drop |
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| CN112717077A (en) * | 2021-01-18 | 2021-04-30 | 胡其勇 | Coarse grain powder for treating type II diabetes |
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Application publication date: 20131204 |