CN103404851A - Garlic oil soft capsules and preparation method thereof - Google Patents
Garlic oil soft capsules and preparation method thereof Download PDFInfo
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- CN103404851A CN103404851A CN2013103145370A CN201310314537A CN103404851A CN 103404851 A CN103404851 A CN 103404851A CN 2013103145370 A CN2013103145370 A CN 2013103145370A CN 201310314537 A CN201310314537 A CN 201310314537A CN 103404851 A CN103404851 A CN 103404851A
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- 239000010647 garlic oil Substances 0.000 title claims abstract description 36
- 239000007901 soft capsule Substances 0.000 title claims abstract description 21
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 240000002234 Allium sativum Species 0.000 claims abstract description 36
- 235000004611 garlic Nutrition 0.000 claims abstract description 35
- 238000000605 extraction Methods 0.000 claims abstract description 15
- 239000002775 capsule Substances 0.000 claims abstract description 13
- 230000002255 enzymatic effect Effects 0.000 claims abstract description 8
- 229910000831 Steel Inorganic materials 0.000 claims abstract description 6
- 229940059442 hemicellulase Drugs 0.000 claims abstract description 6
- 108010002430 hemicellulase Proteins 0.000 claims abstract description 6
- 239000010959 steel Substances 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims abstract description 5
- 238000011049 filling Methods 0.000 claims abstract description 4
- 235000012054 meals Nutrition 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 claims description 15
- 239000002002 slurry Substances 0.000 claims description 14
- 238000012360 testing method Methods 0.000 claims description 5
- 238000005360 mashing Methods 0.000 claims description 4
- 240000007594 Oryza sativa Species 0.000 claims description 3
- 235000007164 Oryza sativa Nutrition 0.000 claims description 3
- 235000008429 bread Nutrition 0.000 claims description 3
- 239000002994 raw material Substances 0.000 claims description 3
- 235000009566 rice Nutrition 0.000 claims description 3
- 239000000341 volatile oil Substances 0.000 claims description 3
- 229940071462 oralone Drugs 0.000 claims description 2
- 238000000926 separation method Methods 0.000 abstract description 3
- 239000000413 hydrolysate Substances 0.000 abstract 3
- 230000004907 flux Effects 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 239000000047 product Substances 0.000 description 7
- JDLKFOPOAOFWQN-VIFPVBQESA-N Allicin Natural products C=CCS[S@](=O)CC=C JDLKFOPOAOFWQN-VIFPVBQESA-N 0.000 description 5
- JDLKFOPOAOFWQN-UHFFFAOYSA-N allicin Chemical compound C=CCSS(=O)CC=C JDLKFOPOAOFWQN-UHFFFAOYSA-N 0.000 description 5
- 235000010081 allicin Nutrition 0.000 description 5
- 238000006911 enzymatic reaction Methods 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 229910052711 selenium Inorganic materials 0.000 description 3
- 239000011669 selenium Substances 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
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- 201000011510 cancer Diseases 0.000 description 2
- PFRGXCVKLLPLIP-UHFFFAOYSA-N diallyl disulfide Chemical compound C=CCSSCC=C PFRGXCVKLLPLIP-UHFFFAOYSA-N 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 description 1
- UUUHXMGGBIUAPW-UHFFFAOYSA-N 1-[1-[2-[[5-amino-2-[[1-[5-(diaminomethylideneamino)-2-[[1-[3-(1h-indol-3-yl)-2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbon Chemical compound C1CCC(C(=O)N2C(CCC2)C(O)=O)N1C(=O)C(C(C)CC)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C1CCC(=O)N1 UUUHXMGGBIUAPW-UHFFFAOYSA-N 0.000 description 1
- PAWQVTBBRAZDMG-UHFFFAOYSA-N 2-(3-bromo-2-fluorophenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC(Br)=C1F PAWQVTBBRAZDMG-UHFFFAOYSA-N 0.000 description 1
- 101100449517 Arabidopsis thaliana GRH1 gene Proteins 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 208000001953 Hypotension Diseases 0.000 description 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 1
- 102000004270 Peptidyl-Dipeptidase A Human genes 0.000 description 1
- 108090000882 Peptidyl-Dipeptidase A Proteins 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 101100434479 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) AFB1 gene Proteins 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- OQIQSTLJSLGHID-WNWIJWBNSA-N aflatoxin B1 Chemical compound C=1([C@@H]2C=CO[C@@H]2OC=1C=C(C1=2)OC)C=2OC(=O)C2=C1CCC2=O OQIQSTLJSLGHID-WNWIJWBNSA-N 0.000 description 1
- 229930020125 aflatoxin-B1 Natural products 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
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- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
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- 238000006555 catalytic reaction Methods 0.000 description 1
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- 239000000470 constituent Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
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- 230000000378 dietary effect Effects 0.000 description 1
- 235000005118 dietary health Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- MRZMQYCKIIJOSW-UHFFFAOYSA-N germanium zinc Chemical compound [Zn].[Ge] MRZMQYCKIIJOSW-UHFFFAOYSA-N 0.000 description 1
- 208000021822 hypotensive Diseases 0.000 description 1
- 230000001077 hypotensive effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
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- 235000001968 nicotinic acid Nutrition 0.000 description 1
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- 230000001590 oxidative effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
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- 230000002265 prevention Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
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- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
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- 239000000126 substance Substances 0.000 description 1
- 150000003464 sulfur compounds Chemical class 0.000 description 1
- 238000000194 supercritical-fluid extraction Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
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- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Preparation Of Fruits And Vegetables (AREA)
Abstract
The invention provides garlic oil soft capsules and a preparation method thereof. The preparation comprises following steps: the peel of garlic which has no moldy or rotten parts and has buds is removed; the garlic is added into a tissue grinder and is grinded into pulp; 18 to 22kg of the garlic pulp is added into an enzymolysis tank, 0.4 to 0.7kg of hemicellulase is added, the mixture is subjected to enzymolysis for 2.8 to 3.2h at a temperature of 42 to 47 DEG C so as to obtain a garlic enzymatic hydrolysate; the garlic enzymatic hydrolysate is added into an extractor, the steel cylinder of the extractor is turned on so as to delivery CO2 into the extractor, the extractor is pre-heated to 33 to 37 DEG C, and the garlic enzymatic hydrolysate is subjected to extraction for 2.8 to 3.3h, wherein the pressure is 16 to 19MPa, and the ratio of the flux of an extraction agent to the flux of the sample material is 5-6LCO2/h.g galic; the garlic oil is obtained after separation; and then a full-automatic capsule filling machine is used for preparation of the garlic oil soft capsules, wherein the weight of each garlic oil soft capsule is 0.2g. Dosage and administration are that: the garlic oil capsules are taken orally, 2 to 3 times a day, and 1 to 2 capsules each time; and the garlic oil capsules should be taken after meal.
Description
Technical field
The present invention relates to health products, the recycling of garlic oil especially, garlic oil soft capsule prepared by the method is used easy to carry.
Background technology
Garlic is encyclopaedia allium garlic (Allium Sativum) bulb, detection shows, in every 100g garlic bulb, contain protein 4.4g, fatty 0.2g, carbohydrate 23g, crude fibre 0.7g, ash content 1.3g, moisture 70g, calcium 5mg, iron 0.4mg, thiamine 0.24mg, riboflavin 0.03mg, niacin 0.9mg, ascorbic acid 3mg and trace elements of selenium, iodine, germanium zinc etc., existing abundant nutrition, can play the health care dietary function again; Wherein the allicin in garlic can kill various bacteria at short notice, ascorbic acid in garlic, can stop the synthetic of carcinogenic substance inferior ammonium nitrate, growth that can also inhibition cancer cell, the effects such as that the solarization element in garlic has is hypotensive, prevention cardiovascular disease, organic germanium can promote human body metabolism to increase the keeping vigor of cell.Garlic oil (Allicin oil) has multiple use, the generation of garlic oil is enzymatic reaction, the various technological parameters that affect enzymatic reaction all will affect speed and the intensity that garlic oil extracts in leaching process, traditional garlic oil synthesizes and purification process, method is loaded down with trivial details, be not suitable for industrial production, supercritical liquid extraction technique (Supercritical Fluid Extraction) is to apply in recent years a more new separation technology, due to its special materialization and high extraction efficiency, day by day be subject to people's favor.Utilize supercritical CO
2Abstraction technique is from garlic, separating garlic oil, for the extraction of garlic oil provides new technique and method, impels the garlic industry to becoming more meticulous and the high added value future development, for the good approach that provides is provided agricultural product.
The Searches of Patent Literature discloses: relevant for the report that adopts aqueous enzymatic method catalysis to obtain, carry in conjunction with supercritical CO but utilize ethanolic solution to help
2The research that abstraction technique prepares garlic oil soft capsule has no bibliographical information.
Innovative point of the present invention: this project adopts aqueous enzymatic method to put forward the mode that oil combines with supercritical liquid extraction technique, and selecting ethanol is entrainer, and effectively lixiviate and protection allicin, prepare the garlic oil soft capsule with high-load allicin.
Summary of the invention
The object of the invention is to: the garlic oil soft capsule of research and development is the special dietary health products, has given prominence to alimentary health-care function, is the deep processing of Xinjiang high-quality garlic oil, has established wide market sale prospect.
The object of the present invention is achieved like this: a kind of garlic oil soft capsule and preparation method thereof, implement step by step;
Step 1 raw material is processed: will put in tissue mashing machine and break into slurry without the garlic peeling that goes rotten, has bud, and stand-by;
Step 2 enzymolysis garlic slurries: get 18-22kg garlic slurry and be placed in enzymatic vessel, add the hemicellulase of 0.4-0.7kg, under 42-47 ℃, enzymolysis 2.8-3.2h, obtain garlic enzymolysis slurries;
Step 3 is extracted garlic oil: the mixture of step 2 is packed in extractor, open the logical CO of steel cylinder
2, be preheated to 33-37 ℃, extraction, pressure is 16-19MPa, the extractant flow is 5～6LCO with the test portion ratio
2/ hg garlic, the time is 2.8-3.3h, separates and obtains garlic oil;
Step 4 prepares capsule: adopt full-automatic capsule filling machine to make the galic essential oil soft capsule, every 0.2g.
Described method, the garlic oil soft capsule made 2～3 times on the oral one, one time 1～2, take after meal or after going with rice or bread.
The mechanism of action of the present invention: garlic oil soft capsule is to help and carry and supercritical CO through enzymolysis, ethanol
2Extraction, process with special process, and assay shows: contained biological activity, can improve body immunity, and suppress and kill cancer cell, Angiotensin-converting enzyme inhibition synthetic, can also increase the oxygen delivery capacity of cell; Selenium is present in the sweet skin peroxidase of paddy moon bright with the form of selenium moon bright propylhomoserin, plays antioxidation, the Cell protection film; Zinc is constituent and the activator of 80 plurality of enzymes in human body.In garlic oil soft capsule, also contain multiple reducible sulfur compound, as diallyl disulfide, the oxidizing process that it can alleviate human body, play anti-aging effects, quite gets consumer reception, and shows technological progress.
The specific embodiment
Below in conjunction with embodiment, invention is described further.
Embodiment
Produce the technological process of garlic oil soft capsule: garlic → selecting, clean, remove the peel → tissue mashing → enzymolysis → supercritical CO
2(pressurization supplements CO in extraction (ethanol) → separation
2) → garlic oil → capsule → check → finished product.
1) pretreatment of raw material: will after peeling, put in tissue mashing machine and pull an oar without the garlic 130kg that goes rotten, sprouts, stand-by;
2) aqueous enzymatic method is carried oil: getting garlic slurry 20kg, add the hemicellulase of 0.4kg in enzymatic vessel, is under the condition of 45 ℃ in temperature, enzymolysis 3h; Obtain garlic enzymolysis slurries; Or get 18kg garlic slurry and be placed in enzymatic vessel, add the hemicellulase of 0.4kg, under 42 ℃, enzymolysis 2.8h, obtain garlic enzymolysis slurries; Or get 22kg garlic slurry and be placed in enzymatic vessel, add the hemicellulase of 0.7kg, under 47 ℃, enzymolysis 3.2h, obtain garlic enzymolysis slurries; Optional one group is implemented supercritical CO
2Extraction.
3) supercritical CO
2Extraction: select ethanol as entrainer, open the logical CO of steel cylinder
2, after preheater is heated to 35 ℃, entering extractor, extracting pressure is 18MPa, the extractant flow is 5.5LCO with the test portion ratio
2/ hg garlic, extraction time is 3h, isolates garlic oil; Or by 2) mixture pack in extractor, open the logical CO of steel cylinder
2, be preheated to 33 ℃, extraction, pressure is 16MPa, the extractant flow is 5LCO with the test portion ratio
2/ hg garlic, the time is 2.8h, separates and obtains garlic oil; Or by 2) mixture pack in extractor, open the logical CO of steel cylinder
2, be preheated to 37 ℃, extraction, pressure is 19MPa, the extractant flow is 6LCO with the test portion ratio
2/ hg garlic, the time is 3.3h, separates and obtains garlic oil; Optional one group prepares capsule.
4) prepare capsule: adopt full-automatic capsule filling machine to be prepared into the galic essential oil soft capsule, every heavy 0.2g.
5) capsule finished product is oral: one time 1～2,2～3 times on the one, after meal or go with rice or bread and take.
This product meets the company standard that Changji Hui Autonomous Prefecture, Xinjiang Minister of the General Administration for Quality Supervision formulates, and is Q/XZZ0045S-2013 " garlic oil soft capsule ".
The product key index
Organoleptic indicator: yellow transparent soft capsule
Physical and chemical index: contain allicin 2.59mg in every, protein 94mg, ɑ-tocopherol IU, iron 0.1ug, polyunsaturated fatty acid 87mg, VE=0.47mg, VA=0.61mg, V B1=0.16mg, V B2=2.88mg, VB6=1.69mg, acid value ﹤ 0.3mgKOH/g, peroxide value ﹤ 10meq/kg, carbonyl valency ﹤ 10meq/kg, AFB1 ﹤ 10 μ g/kg.
Microbiological indicator: total plate count<1 (cfu/ml); Coliform<3 (MPN/100ml); Pathogenic bacteria do not detect.
Claims (2)
1. garlic oil soft capsule and preparation method thereof, is characterized in that: implement step by step;
Step 1 raw material is processed: will put in tissue mashing machine and break into slurry without the garlic peeling that goes rotten, has bud, and stand-by;
Step 2 enzymolysis garlic slurries: get 18-22kg garlic slurry and be placed in enzymatic vessel, add the hemicellulase of 0.4-0.7kg, under 42-47 ℃, enzymolysis 2.8-3.2h, obtain garlic enzymolysis slurries;
Step 3 is extracted garlic oil: the mixture of step 2 is packed in extractor, open the logical CO of steel cylinder
2, be preheated to 33-37 ℃, extraction, pressure is 16-19MPa, the extractant flow is 5～6LCO with the test portion ratio
2/ hg garlic, the time is 2.8-3.3h, separates and obtains garlic oil;
Step 4 prepares capsule: adopt full-automatic capsule filling machine to make the galic essential oil soft capsule, every heavy 0.2g.
2. according to the described method of right 1, it is characterized in that: the garlic oil soft capsule made 2～3 times on the oral one, one time 1～2, take after meal or after going with rice or bread.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310314537.0A CN103404851B (en) | 2013-07-24 | 2013-07-24 | Garlic oil soft capsules and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310314537.0A CN103404851B (en) | 2013-07-24 | 2013-07-24 | Garlic oil soft capsules and preparation method thereof |
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| CN103404851A true CN103404851A (en) | 2013-11-27 |
| CN103404851B CN103404851B (en) | 2015-01-07 |
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| CN201310314537.0A Expired - Fee Related CN103404851B (en) | 2013-07-24 | 2013-07-24 | Garlic oil soft capsules and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103695152A (en) * | 2014-01-09 | 2014-04-02 | 长沙市博泰生物科技有限公司 | Enzyme method and supercritical CO2 extraction combined method for extracting sea buckthorn fruit oil |
| CN104068136A (en) * | 2014-06-18 | 2014-10-01 | 佘鹏 | Garlic oil |
| CN105238565A (en) * | 2015-10-29 | 2016-01-13 | 广东欧莱氏生物科技有限公司 | Extraction process for garlic essential oil |
| CN107549859A (en) * | 2017-09-19 | 2018-01-09 | 太仓市林港农场专业合作社 | A kind of immune soft capsule of galic essential oil compound enhancing and preparation method thereof |
| CN112294780A (en) * | 2020-10-15 | 2021-02-02 | 苏州大学 | Modulators, test methods and uses for modulating angiotensin-converting enzyme 2 activity |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107596158A (en) * | 2017-09-19 | 2018-01-19 | 太仓市林港农场专业合作社 | A kind of galic essential oil compound auxiliary blood fat reducing soft capsule and preparation method thereof |
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2013
- 2013-07-24 CN CN201310314537.0A patent/CN103404851B/en not_active Expired - Fee Related
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103695152A (en) * | 2014-01-09 | 2014-04-02 | 长沙市博泰生物科技有限公司 | Enzyme method and supercritical CO2 extraction combined method for extracting sea buckthorn fruit oil |
| CN104068136A (en) * | 2014-06-18 | 2014-10-01 | 佘鹏 | Garlic oil |
| CN105238565A (en) * | 2015-10-29 | 2016-01-13 | 广东欧莱氏生物科技有限公司 | Extraction process for garlic essential oil |
| CN107549859A (en) * | 2017-09-19 | 2018-01-09 | 太仓市林港农场专业合作社 | A kind of immune soft capsule of galic essential oil compound enhancing and preparation method thereof |
| CN107549859B (en) * | 2017-09-19 | 2019-11-01 | 太仓市林港农场专业合作社 | A kind of galic essential oil compound enhances immune soft capsule and preparation method thereof |
| CN112294780A (en) * | 2020-10-15 | 2021-02-02 | 苏州大学 | Modulators, test methods and uses for modulating angiotensin-converting enzyme 2 activity |
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