CN103403017A - 新19-去甲类固醇及其用于治疗孕酮依赖病况的用途 - Google Patents
新19-去甲类固醇及其用于治疗孕酮依赖病况的用途 Download PDFInfo
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- CN103403017A CN103403017A CN2011800682607A CN201180068260A CN103403017A CN 103403017 A CN103403017 A CN 103403017A CN 2011800682607 A CN2011800682607 A CN 2011800682607A CN 201180068260 A CN201180068260 A CN 201180068260A CN 103403017 A CN103403017 A CN 103403017A
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- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| USPCT/US10/062068 | 2010-12-23 | ||
| PCT/US2010/062068 WO2011119194A1 (en) | 2010-03-22 | 2010-12-23 | Compositions and methods for non-toxic delivery of antiprogestins |
| PCT/US2011/050859 WO2012087389A1 (en) | 2010-12-23 | 2011-09-08 | Novel 19-nor-steroids and their use for treating progesterone-dependent conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103403017A true CN103403017A (zh) | 2013-11-20 |
Family
ID=44681424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011800682607A Pending CN103403017A (zh) | 2010-12-23 | 2011-09-08 | 新19-去甲类固醇及其用于治疗孕酮依赖病况的用途 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20130274234A1 (enExample) |
| EP (1) | EP2655394A1 (enExample) |
| JP (2) | JP2014500316A (enExample) |
| KR (1) | KR20130132955A (enExample) |
| CN (1) | CN103403017A (enExample) |
| AU (1) | AU2011345341B2 (enExample) |
| CA (1) | CA2820877A1 (enExample) |
| MX (1) | MX2013006732A (enExample) |
| NZ (1) | NZ612295A (enExample) |
| SG (1) | SG191207A1 (enExample) |
| UA (1) | UA113283C2 (enExample) |
| WO (1) | WO2012087389A1 (enExample) |
| ZA (1) | ZA201304381B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201704858PA (en) | 2012-05-31 | 2017-07-28 | Repros Therapeutics Inc | Formulations and methods for vaginal delivery of antiprogestins |
| EP2914268B1 (en) * | 2012-11-02 | 2018-07-04 | Repros Therapeutics Inc. | Methods and compositions for treating progesterone-dependent conditions |
| MX384159B (es) * | 2014-05-05 | 2025-03-14 | Repros Therapeutics Inc | Formulaciones y métodos para el suministro vaginal de antiprogestinas. |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050143364A1 (en) * | 1996-05-01 | 2005-06-30 | Kim Hyun K. | 21-Substituted progesterone derivatives as new antiprogestational agents |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2521565B1 (fr) | 1982-02-17 | 1985-07-05 | Dior Sa Parfums Christian | Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees |
| FR2534487B1 (fr) | 1982-10-15 | 1988-06-10 | Dior Christian Parfums | Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede |
| ATE151286T1 (de) | 1983-11-14 | 1997-04-15 | Columbia Lab Inc | Bioadhäsive mittel |
| FR2573657B1 (fr) * | 1984-11-29 | 1989-05-12 | Roussel Uclaf | Produit comprenant une substance antiprogestomimetique et une substance uterotonique |
| US4954490A (en) * | 1988-06-23 | 1990-09-04 | Research Triangle Institute | 11 β-substituted progesterone analogs |
| US5077211A (en) | 1988-07-06 | 1991-12-31 | Applied Genetics, Inc. | Purification and administration of dna repair enzymes |
| US6900193B1 (en) * | 1996-05-01 | 2005-05-31 | The United States Of America As Represented By The Department Of Health And Human Services | Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents |
| US6020328A (en) * | 1998-03-06 | 2000-02-01 | Research Triangle Institute | 20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties |
| DK1265911T3 (da) * | 2000-03-17 | 2008-09-29 | Us Gov Health & Human Serv | 17-alfa-substitueret-11-beta-substitueret-4-aryl og 21-substitueret 19-norpregnadiendion som antiprogestationelle midler |
| EP2078032B1 (en) * | 2006-10-24 | 2017-08-02 | Repros Therapeutics Inc. | Compositions and methods for suppressing endometrial proliferation |
| WO2009061569A1 (en) * | 2007-11-05 | 2009-05-14 | Repros Therapeutics Inc. | Compositions and methods for treating dysfunctional uterine bleeding |
| TWI477276B (zh) * | 2008-04-28 | 2015-03-21 | Repros Therapeutics Inc | 抗黃體素給藥方案 |
| TWI539953B (zh) * | 2008-04-28 | 2016-07-01 | 瑞波若斯治療學公司 | 用於治療乳癌之組成物和方法 |
-
2011
- 2011-08-09 UA UAA201309244A patent/UA113283C2/uk unknown
- 2011-09-08 JP JP2013546126A patent/JP2014500316A/ja not_active Withdrawn
- 2011-09-08 SG SG2013046602A patent/SG191207A1/en unknown
- 2011-09-08 NZ NZ612295A patent/NZ612295A/en not_active IP Right Cessation
- 2011-09-08 WO PCT/US2011/050859 patent/WO2012087389A1/en not_active Ceased
- 2011-09-08 US US13/997,097 patent/US20130274234A1/en not_active Abandoned
- 2011-09-08 CA CA2820877A patent/CA2820877A1/en not_active Abandoned
- 2011-09-08 MX MX2013006732A patent/MX2013006732A/es unknown
- 2011-09-08 EP EP11761438.8A patent/EP2655394A1/en not_active Withdrawn
- 2011-09-08 CN CN2011800682607A patent/CN103403017A/zh active Pending
- 2011-09-08 KR KR1020137019568A patent/KR20130132955A/ko not_active Ceased
- 2011-09-08 AU AU2011345341A patent/AU2011345341B2/en not_active Ceased
-
2013
- 2013-06-13 ZA ZA2013/04381A patent/ZA201304381B/en unknown
-
2016
- 2016-07-08 JP JP2016135644A patent/JP2016180004A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050143364A1 (en) * | 1996-05-01 | 2005-06-30 | Kim Hyun K. | 21-Substituted progesterone derivatives as new antiprogestational agents |
Non-Patent Citations (1)
| Title |
|---|
| -: "RN：365416-59-7", 《STN ON WEB》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011345341B2 (en) | 2016-10-20 |
| US20130274234A1 (en) | 2013-10-17 |
| WO2012087389A1 (en) | 2012-06-28 |
| EP2655394A1 (en) | 2013-10-30 |
| AU2011345341A1 (en) | 2013-07-04 |
| NZ612295A (en) | 2014-07-25 |
| CA2820877A1 (en) | 2012-06-28 |
| SG191207A1 (en) | 2013-07-31 |
| JP2016180004A (ja) | 2016-10-13 |
| MX2013006732A (es) | 2013-07-17 |
| ZA201304381B (en) | 2014-03-26 |
| JP2014500316A (ja) | 2014-01-09 |
| UA113283C2 (xx) | 2017-01-10 |
| KR20130132955A (ko) | 2013-12-05 |
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