CN103398952A - 生物传感器检测中的导模共振滤波片反射率优化方法 - Google Patents
生物传感器检测中的导模共振滤波片反射率优化方法 Download PDFInfo
- Publication number
- CN103398952A CN103398952A CN2013103511911A CN201310351191A CN103398952A CN 103398952 A CN103398952 A CN 103398952A CN 2013103511911 A CN2013103511911 A CN 2013103511911A CN 201310351191 A CN201310351191 A CN 201310351191A CN 103398952 A CN103398952 A CN 103398952A
- Authority
- CN
- China
- Prior art keywords
- filter
- mode resonance
- modification level
- bandwidth
- optimization method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims abstract description 12
- 238000005457 optimization Methods 0.000 title claims abstract description 11
- 238000001514 detection method Methods 0.000 title abstract description 11
- 230000003287 optical effect Effects 0.000 claims abstract description 19
- 238000012360 testing method Methods 0.000 claims abstract description 12
- 230000000694 effects Effects 0.000 claims abstract description 9
- 239000000463 material Substances 0.000 claims abstract description 7
- 239000013307 optical fiber Substances 0.000 claims abstract description 4
- 230000004048 modification Effects 0.000 claims description 20
- 238000012986 modification Methods 0.000 claims description 20
- 230000008859 change Effects 0.000 claims description 7
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 6
- 238000002310 reflectometry Methods 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 5
- 239000000758 substrate Substances 0.000 claims description 4
- 108090001008 Avidin Proteins 0.000 claims description 3
- 229960002685 biotin Drugs 0.000 claims description 3
- 235000020958 biotin Nutrition 0.000 claims description 3
- 239000011616 biotin Substances 0.000 claims description 3
- 230000008878 coupling Effects 0.000 claims description 3
- 238000010168 coupling process Methods 0.000 claims description 3
- 238000005859 coupling reaction Methods 0.000 claims description 3
- 238000006884 silylation reaction Methods 0.000 claims description 3
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims description 2
- 229910000077 silane Inorganic materials 0.000 claims description 2
- 238000007689 inspection Methods 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 abstract description 4
- 238000001179 sorption measurement Methods 0.000 abstract 1
- 238000010586 diagram Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000004038 photonic crystal Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Images
Landscapes
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
Description
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310351191.1A CN103398952B (zh) | 2013-08-13 | 2013-08-13 | 生物传感器检测中的导模共振滤波片反射率优化方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310351191.1A CN103398952B (zh) | 2013-08-13 | 2013-08-13 | 生物传感器检测中的导模共振滤波片反射率优化方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103398952A true CN103398952A (zh) | 2013-11-20 |
| CN103398952B CN103398952B (zh) | 2016-01-20 |
Family
ID=49562618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310351191.1A Expired - Fee Related CN103398952B (zh) | 2013-08-13 | 2013-08-13 | 生物传感器检测中的导模共振滤波片反射率优化方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103398952B (zh) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103969185A (zh) * | 2014-05-19 | 2014-08-06 | 上海理工大学 | 一种提高导模共振生物传感器测试灵敏度的方法 |
| CN105606219A (zh) * | 2016-02-17 | 2016-05-25 | 上海理工大学 | 带楔形波导层导模共振滤波片的微型光谱仪 |
| CN111208060A (zh) * | 2020-02-14 | 2020-05-29 | 复旦大学 | 传感芯片及其制备方法、检测系统和检测方法 |
| CN114675360A (zh) * | 2020-12-25 | 2022-06-28 | 郑宏志 | 一种导模共振窄带滤波单元结构及多光谱芯片 |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060193550A1 (en) * | 1999-11-05 | 2006-08-31 | Wawro Debra D | Methods for using resonant waveguide-grating filters and sensors |
| CN1971267A (zh) * | 2005-11-23 | 2007-05-30 | 财团法人工业技术研究院 | 波导耦合表面等离子体共振生物传感器 |
| JP2008046093A (ja) * | 2006-08-21 | 2008-02-28 | National Institute Of Advanced Industrial & Technology | 細孔付き光導波モードセンサー |
| CN101548211A (zh) * | 2006-12-05 | 2009-09-30 | 韩国电子通信研究院 | 包含高折射率有机材料的导向模式共振过滤器及包含该导向模式共振过滤器的光学生物传感器 |
| US7756365B2 (en) * | 2006-07-07 | 2010-07-13 | University Of Illinois | Near ultraviolet-wavelength photonic-crystal biosensor with enhanced surface to bulk sensitivity ratio |
| CN102288552A (zh) * | 2006-09-08 | 2011-12-21 | 罗伯特·马格努松 | 利用角、光谱、模态和偏振分集的用于高精度感测的紧凑形式导模共振传感器 |
| CN102317781A (zh) * | 2008-12-15 | 2012-01-11 | Sru生物系统公司 | 细胞中变化的检测方法 |
| TW201305549A (zh) * | 2011-07-19 | 2013-02-01 | Univ Nat Central | 具金屬緩衝層之波導共振生物感測器 |
-
2013
- 2013-08-13 CN CN201310351191.1A patent/CN103398952B/zh not_active Expired - Fee Related
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060193550A1 (en) * | 1999-11-05 | 2006-08-31 | Wawro Debra D | Methods for using resonant waveguide-grating filters and sensors |
| CN1971267A (zh) * | 2005-11-23 | 2007-05-30 | 财团法人工业技术研究院 | 波导耦合表面等离子体共振生物传感器 |
| US7756365B2 (en) * | 2006-07-07 | 2010-07-13 | University Of Illinois | Near ultraviolet-wavelength photonic-crystal biosensor with enhanced surface to bulk sensitivity ratio |
| JP2008046093A (ja) * | 2006-08-21 | 2008-02-28 | National Institute Of Advanced Industrial & Technology | 細孔付き光導波モードセンサー |
| CN102288552A (zh) * | 2006-09-08 | 2011-12-21 | 罗伯特·马格努松 | 利用角、光谱、模态和偏振分集的用于高精度感测的紧凑形式导模共振传感器 |
| CN101548211A (zh) * | 2006-12-05 | 2009-09-30 | 韩国电子通信研究院 | 包含高折射率有机材料的导向模式共振过滤器及包含该导向模式共振过滤器的光学生物传感器 |
| CN102317781A (zh) * | 2008-12-15 | 2012-01-11 | Sru生物系统公司 | 细胞中变化的检测方法 |
| TW201305549A (zh) * | 2011-07-19 | 2013-02-01 | Univ Nat Central | 具金屬緩衝層之波導共振生物感測器 |
Non-Patent Citations (5)
| Title |
|---|
| KEHUI JIA ET AL.: "Fabrication Error Analysis and Compensation for Guided-Mode Resonance Biosensor", 《IEEE PHOTONICS TECHNOLOGY LETTERS》 * |
| QI WANG ET AL.: "Ssensitivity of a Label-Free Guided-Mode Resonant optical Biosensor with Different Modes", 《SENSORS》 * |
| R.MAGNUSSON ET AL.: "Guided-mode resonance sensors for biochemical screening", 《2007 IEEE LEOS ANNUAL MEETING CONFERENCE PROCEEDINGS》 * |
| ROBERT MAGNUSSON ET AL.: "Resonant Photonic Biosensors with Polarization-Based Multiparametric Discrimination in Each Channel", 《SENSORS》 * |
| 张大伟 等: "导模共振光学生物传感器的研究", 《中国光学学会2010年光学大会论文集》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103969185A (zh) * | 2014-05-19 | 2014-08-06 | 上海理工大学 | 一种提高导模共振生物传感器测试灵敏度的方法 |
| CN103969185B (zh) * | 2014-05-19 | 2016-09-14 | 上海理工大学 | 一种提高导模共振生物传感器测试灵敏度的方法 |
| CN105606219A (zh) * | 2016-02-17 | 2016-05-25 | 上海理工大学 | 带楔形波导层导模共振滤波片的微型光谱仪 |
| CN105606219B (zh) * | 2016-02-17 | 2017-11-28 | 上海理工大学 | 带楔形波导层导模共振滤波片的微型光谱仪 |
| CN111208060A (zh) * | 2020-02-14 | 2020-05-29 | 复旦大学 | 传感芯片及其制备方法、检测系统和检测方法 |
| CN114675360A (zh) * | 2020-12-25 | 2022-06-28 | 郑宏志 | 一种导模共振窄带滤波单元结构及多光谱芯片 |
| CN114675360B (zh) * | 2020-12-25 | 2024-03-08 | 广州睿芯微电子有限公司 | 一种导模共振窄带滤波单元结构及多光谱芯片 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103398952B (zh) | 2016-01-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100458406C (zh) | 光纤微结构马赫-曾德尔干涉式spr化学生物传感器及系统 | |
| EP2237022B1 (en) | Flow rate measurement apparatus and method | |
| US20110188030A1 (en) | Microelectronic sensor device for optical examinations in a sample medium | |
| Liu et al. | Wavelength-modulation surface plasmon resonance sensor | |
| KR100927655B1 (ko) | 바이오 감지 센서 | |
| US20110216320A1 (en) | Multi-channel surface plasmon resonance sensor using beam profile ellipsometry | |
| WO2019141287A1 (zh) | 基于有序多孔纳米结构薄膜干涉效应的生物检测仪及其进行生物分子检测的方法 | |
| CN103398952B (zh) | 生物传感器检测中的导模共振滤波片反射率优化方法 | |
| Xiao et al. | Print-and-stick unibody microfluidics coupled surface plasmon resonance (SPR) chip for smartphone imaging SPR (Smart-iSRP) | |
| CN101871881B (zh) | 一种检测溶液中蛋白质含量的方法 | |
| Jain et al. | Smartphone integrated handheld Long Range Surface Plasmon Resonance based fiber-optic biosensor with tunable SiO2 sensing matrix | |
| EP2653853A1 (en) | Intermolecular interaction measurement method, measurement system for use in the method, and program | |
| US10884193B2 (en) | Dual grating sensing system, dual grating sensor and detecting method thereof | |
| CN101825629B (zh) | 波导耦合金属光子晶体生物传感器及其检测方法 | |
| CN100561198C (zh) | 光纤微结构迈克尔逊干涉式表面等离子共振化学与生物传感器及系统 | |
| Chen et al. | A low cost surface plasmon resonance biosensor using a laser line generator | |
| US20130130939A1 (en) | Portable photonic sensor system as an early detection tool for ovarian cancer | |
| WO2014020159A1 (en) | Interferometric detection method | |
| TW200526943A (en) | Precision correction of reflectance measurements | |
| WO2009078510A1 (en) | Disposable surface plasmon resonance biosensor and system using the same | |
| CN107064061A (zh) | 超高分辨折射率仪 | |
| CN104237169B (zh) | 一种基于外场调制的spr检测系统的检测方法 | |
| Lee et al. | Enhancing performance of a miniaturized surface plasmon resonance sensor in the reflectance detection mode using a waveguide-coupled bimetallic chip | |
| CN113702297B (zh) | 一种生物传感器系统及其应用于检测生物样品的方法 | |
| CN201434868Y (zh) | 波导耦合金属光子晶体生物传感器 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent of invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Qi Inventor after: Tao Chunxian Inventor after: Qian Linyong Inventor after: Xu Banglian Inventor after: Wang Zhenyun Inventor after: Zhang Dawei Inventor after: Huang Yuanshen Inventor after: Hong Ruijin Inventor after: Ni Zhengji Inventor after: Sheng Bin Inventor before: Wang Zhenyun Inventor before: Wang Qi Inventor before: Zhang Dawei Inventor before: Huang Yuanshen Inventor before: Hong Ruijin Inventor before: Ni Zhengji Inventor before: Sheng Bin Inventor before: Tao Chunxian |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: WANG ZHENYUN WANG QI ZHANG DAWEI HUANG YUANSHEN HONG RUIJIN NI ZHENGJI SHENG BIN TAO CHUNXIAN TO: WANG QI QIAN LINYONG XU BANGLIAN WANG ZHENYUN ZHANG DAWEI HUANG YUANSHEN HONG RUIJIN NI ZHENGJI SHENG BIN TAO CHUNXIAN |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Qi Inventor after: Tao Chunxian Inventor after: Sun Haojie Inventor after: Qian Linyong Inventor after: Xu Banglian Inventor after: Wang Zhenyun Inventor after: Zhang Dawei Inventor after: Huang Yuanshen Inventor after: Hong Ruijin Inventor after: Ni Zhengji Inventor after: Sheng Bin Inventor before: Wang Qi Inventor before: Tao Chunxian Inventor before: Qian Linyong Inventor before: Xu Banglian Inventor before: Wang Zhenyun Inventor before: Zhang Dawei Inventor before: Huang Yuanshen Inventor before: Hong Ruijin Inventor before: Ni Zhengji Inventor before: Sheng Bin |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170317 Address after: 200093 Shanghai military road, Yangpu District, No. 516 Patentee after: University of Shanghai for Science and Technology Patentee after: Shanghai Publishing and Printing College Address before: 200093 Shanghai military road, Yangpu District, No. 516 Patentee before: University of Shanghai for Science and Technology |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160120 Termination date: 20180813 |