CN103396417A - 新型羟肟酸衍生物及其医疗应用 - Google Patents
新型羟肟酸衍生物及其医疗应用 Download PDFInfo
- Publication number
- CN103396417A CN103396417A CN2013103535916A CN201310353591A CN103396417A CN 103396417 A CN103396417 A CN 103396417A CN 2013103535916 A CN2013103535916 A CN 2013103535916A CN 201310353591 A CN201310353591 A CN 201310353591A CN 103396417 A CN103396417 A CN 103396417A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (10)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310353591.6A CN103396417B (zh) | 2013-08-14 | 2013-08-14 | 新型羟肟酸衍生物及其医疗应用 |
PCT/CN2014/084068 WO2015021894A1 (zh) | 2013-08-14 | 2014-08-11 | 新型羟肟酸衍生物及其医疗应用 |
US14/909,553 US9695181B2 (en) | 2013-08-14 | 2014-08-11 | Hydroximic acid derivatives and medical applications therof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310353591.6A CN103396417B (zh) | 2013-08-14 | 2013-08-14 | 新型羟肟酸衍生物及其医疗应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103396417A true CN103396417A (zh) | 2013-11-20 |
CN103396417B CN103396417B (zh) | 2015-02-04 |
Family
ID=49560185
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310353591.6A Active CN103396417B (zh) | 2013-08-14 | 2013-08-14 | 新型羟肟酸衍生物及其医疗应用 |
Country Status (3)
Country | Link |
---|---|
US (1) | US9695181B2 (zh) |
CN (1) | CN103396417B (zh) |
WO (1) | WO2015021894A1 (zh) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015021894A1 (zh) * | 2013-08-14 | 2015-02-19 | 双飞人制药(中国)有限公司 | 新型羟肟酸衍生物及其医疗应用 |
CN107513064A (zh) * | 2017-09-27 | 2017-12-26 | 南昌大学 | 一种嘌呤异羟肟酸衍生物及其制备方法和应用 |
CN111662296A (zh) * | 2020-06-02 | 2020-09-15 | 山东大学 | 一种含吡唑并嘧啶的异羟肟酸衍生物及其制备方法和应用 |
CN111848629A (zh) * | 2020-07-15 | 2020-10-30 | 安徽中医药大学 | 一类mTOR/HDAC双重抑制剂及其应用 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2939730T3 (es) | 2019-01-17 | 2023-04-26 | Univ Lille | Compuestos de heteroarilo de 5 miembros que contienen un resto hidroxamato y su uso |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007054831A2 (en) * | 2005-05-20 | 2007-05-18 | Methylgene, Inc. | Inhibitors of vegf receptor and hgf receptor signaling |
WO2008033745A2 (en) * | 2006-09-11 | 2008-03-20 | Curis, Inc. | Fused bicyclic pyrimidines as ptk inhibitors containing a zinc binding moiety |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX343929B (es) * | 2011-04-04 | 2016-11-28 | Pharmascience Inc | Inhibidores de proteina cinasa. |
CN103396417B (zh) * | 2013-08-14 | 2015-02-04 | 冯子侠 | 新型羟肟酸衍生物及其医疗应用 |
-
2013
- 2013-08-14 CN CN201310353591.6A patent/CN103396417B/zh active Active
-
2014
- 2014-08-11 WO PCT/CN2014/084068 patent/WO2015021894A1/zh active Application Filing
- 2014-08-11 US US14/909,553 patent/US9695181B2/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007054831A2 (en) * | 2005-05-20 | 2007-05-18 | Methylgene, Inc. | Inhibitors of vegf receptor and hgf receptor signaling |
WO2008033745A2 (en) * | 2006-09-11 | 2008-03-20 | Curis, Inc. | Fused bicyclic pyrimidines as ptk inhibitors containing a zinc binding moiety |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015021894A1 (zh) * | 2013-08-14 | 2015-02-19 | 双飞人制药(中国)有限公司 | 新型羟肟酸衍生物及其医疗应用 |
CN107513064A (zh) * | 2017-09-27 | 2017-12-26 | 南昌大学 | 一种嘌呤异羟肟酸衍生物及其制备方法和应用 |
CN107513064B (zh) * | 2017-09-27 | 2019-07-09 | 南昌大学 | 一种嘌呤异羟肟酸衍生物及其制备方法和应用 |
CN111662296A (zh) * | 2020-06-02 | 2020-09-15 | 山东大学 | 一种含吡唑并嘧啶的异羟肟酸衍生物及其制备方法和应用 |
CN111848629A (zh) * | 2020-07-15 | 2020-10-30 | 安徽中医药大学 | 一类mTOR/HDAC双重抑制剂及其应用 |
Also Published As
Publication number | Publication date |
---|---|
US9695181B2 (en) | 2017-07-04 |
US20160176879A1 (en) | 2016-06-23 |
WO2015021894A1 (zh) | 2015-02-19 |
CN103396417B (zh) | 2015-02-04 |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: SHUANGFEIREN PHARMACEUTICAL (CHINA) CO., LTD. Effective date: 20140520 |
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C41 | Transfer of patent application or patent right or utility model | ||
C53 | Correction of patent of invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Feng Zixia Inventor after: Cao Zhenghong Inventor before: Feng Zixia |
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COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: FENG ZIXIA TO: FENG ZIXIA CAO ZHENGHONG |
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TA01 | Transfer of patent application right |
Effective date of registration: 20140520 Address after: Suzhou City, Jiangsu province 215021 Industrial Park Suzhou Xinghan Street No. 185 District 10 building room 801 building Applicant after: Feng Zixia Applicant after: Flying man (Chinese) Pharmaceutical Co. Ltd. Address before: Suzhou City, Jiangsu province 215021 Industrial Park Suzhou Xinghan Street No. 185 District 10 building room 801 building Applicant before: Feng Zixia |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee | ||
CP01 | Change in the name or title of a patent holder |
Address after: Suzhou City, Jiangsu province 215021 Industrial Park Suzhou Xinghan Street No. 185 District 10 building room 801 building Patentee after: Feng Zixia Patentee after: SHUANGFEIREN PHARMACEUTICAL CO., LTD. Address before: Suzhou City, Jiangsu province 215021 Industrial Park Suzhou Xinghan Street No. 185 District 10 building room 801 building Patentee before: Feng Zixia Patentee before: Flying man (Chinese) Pharmaceutical Co. Ltd. |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20210519 Address after: 330096 3rd floor, podium building, Gaohang building, 899 Huoju 5th Road, Nanchang hi tech Industrial Development Zone, Nanchang City, Jiangxi Province Patentee after: Nanchang double Angel Biotechnology Development Co.,Ltd. Address before: 215021 room 801, building 10, Tianyu community, 185 Xinghan street, Suzhou Industrial Park, Suzhou City, Jiangsu Province Patentee before: Feng Zixia Patentee before: SHUANGFEIREN PHARMACEUTICAL Co.,Ltd. |