CN103394032B - Chinese medicinal external lotion for treating neonatal jaundice - Google Patents
Chinese medicinal external lotion for treating neonatal jaundice Download PDFInfo
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- CN103394032B CN103394032B CN201310322249.XA CN201310322249A CN103394032B CN 103394032 B CN103394032 B CN 103394032B CN 201310322249 A CN201310322249 A CN 201310322249A CN 103394032 B CN103394032 B CN 103394032B
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Abstract
The invention discloses a Chinese medicinal external lotion for treating neonatal jaundice. The pathogenesis of the neonatal jaundice is that the spleen and stomach have pathogenic dampness implication, liver dysfunction is caused, and the bile overflows and becomes yellow. Therefore, the Chinese medicinal external lotion is prepared from the Chinese medicaments including golden-rod, small-leaved desmodium, multiflora rose, abrus cantoniensis hance, calanthe discolor lindl, desmodium styracifolium and radix curcumae which have the effects of clearing heat and promoting diuresis, dispersing the liver depression, removing stasis to relieve dyspepsia and removing blood stasis. The prepared Chinese medicinal external lotion is used for soaking and washing the body surface of a newbron, and clinical tests show that the visible efficiency and the total efficiency reach 77.3% and 96.0% respectively and are obviously superior to those of a control group; the serum bilirubin is reduced to a normally needed time which is obviously shorter than that of the control group; and the sleeping quality is better than that of the control group. The treatment method is simple and the cost is low, so that the Chinese medicinal external lotion is worthy of clinical popularization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of external washout with traditional Chinese herbs agent for the treatment of neonatal jaundice.
Background technology
Neonatal jaundice is usual diseases of childhood, how within 2～4 days after birth, to occur, and be the neonate common sympton in period, due to neonatal bilirubin metabolism, approximately there are 50% term infant and 80% premature infant can occur naked eyes jaundice.Clinical jaundice is divided into physiologic jaundice and pathological jaundice, as treatment can cause bilirubin encephalopathy not in time, makes central nervous system impaired, serious threat Neonatal Health and life.Treatment neonatal jaundice method is more, as simple blue light illumination, and oral western medicine, Chinese medicine, herbal enema etc., neonate oral drugs are more difficult, add oral drugs side effect large, brought certain difficulty to treatment neonate treatment jaundice.External washout with traditional Chinese herbs agent has overcome the difficulty of neonate oral drugs, and easy to operation effective, is treatment and the effective method of early intervention treatment neonatal jaundice.
Summary of the invention
The object of this invention is to provide a kind of external washout with traditional Chinese herbs agent for the treatment of neonatal jaundice.Neonatal jaundice belongs to Chinese medicine " pregnant jaundice " category, and main cause is because impression is damp and hot, stagnation of cold-damp, and alluvial jaundice, pathogenesis is to accumulate in taste damp, the liver failing to maintain the normal flow of QI, the excessive and jaundice that arrives of bile.
The object of the invention is to be achieved through the following technical solutions, the external washout with traditional Chinese herbs agent of this treatment neonatal jaundice is made by the Chinese medicine of following weight portion: Herba Solidaginis 15-20 part, Herba desmodii microphylli 13-15 part, Radix Rosae Platyphyllae 10-13 part, Herba Abri 9-14 part, Herba seu Radix Calanthes 7-16 part, Herba Desmodii Styracifolii 15-18 part, Radix Curcumae 13-15 part.
Preferably, 18 parts of Herba Solidaginiss, 14 parts of Herba desmodii microphyllis, 12 parts of Radix Rosae Platyphyllaes, 11 parts of Herba Abris, 13 parts of Herba seu Radix Calanthess, 16 parts of Herba Desmodii Styracifoliis, 14 parts of Radix Curcumaes.
Preparation method: above-mentioned Chinese medicine is put into water and soak, then use slow fire fried, filter fried medicine juice standby.
In side: Herba Solidaginis wind and heat dispersing, subduing swelling and detoxicating; Herba desmodii microphylli, Radix Rosae Platyphyllae, Herba Abri clearing away heat-damp and promoting diuresis, depressed liver-energy dispersing and function of gallbladder promoting, heat-clearing and toxic substances removing, soothing liver-QI dissipating blood stasis; Herba seu Radix Calanthes, Herba Desmodii Styracifolii, Radix Curcumae powder detoxifcation, relaxing muscles and tendons to promote blood circulation, relieving stranguria by diuresis, dampness removing jaundice eliminating, blood-activating and qi-promoting pain relieving, resolving depression mood, removing heat from blood.
Clinical data
1, the selected the court of physical data Students jaundice infant 150 examples, male 78 examples, female's 72 examples, age in days 2～23 days, body weight 2750～4600g.Be divided at random treatment group 75 examples, matched group 75 examples.Two groups of ages, sex, body weight, state of an illness comparison, no significant difference (all P > 0.05).
2,1. diagnostic criteria occurs jaundice increasing the weight of for 4～5 days after term infant birth for 2～3 days, within 1～2 week, disappear, and serum bilirubin 2～12mg/dl, systemic conditions is good, without other clinical symptoms.2. there is morning, heavier, the continuity of disappearing, serum bilirubin≤12mg/dl, the speed < 5mg/dl that every day, serum bilirubin rose in premature infant, dehydration or hungry person's jaundice.
3, Therapeutic Method treatment group jaundice infant is used external washout with traditional Chinese herbs agent of the present invention, take Herba Solidaginis 18g, Herba desmodii microphylli 14g, Radix Rosae Platyphyllae 12g, Herba Abri 11g, Herba seu Radix Calanthes 13g, Herba Desmodii Styracifolii 16g, Radix Curcumae 14g, adding water 5500ml soaks, slow fire is fried, extracting juice 5000ml, it is suitable to be watered to temperature, and children's is embraced into foam washing wherein 15 minutes, clear water rinses 1 time, 1 time/d; Conventional western medical treatment+the Tuihuang oral liquid of matched group.Two groups equal 5 days is a course for the treatment of.
4, criterion of therapeutical effect is cured: skin, mucosa and sclera jaundice disappear substantially, serum bilirubin < 100 μ mol/L; Effective: skin, mucosa and sclera jaundice obviously before alleviate, serum bilirubin 100～205 μ mol/L; Invalid: skin, mucosa and sclera jaundice be without alleviating, serum bilirubin > 205 μ mol/L.
Observation index: serum bilirubin is down to normal required time; Sleep: the > 4h that sleeps is continuously for to sleep; Sleep < 1h is poor for sleeping continuously.
5, therapeutic outcome (1) treatment is added up curative effect after the course for the treatment of.Treatment group 75 examples, wherein cure 58 examples (77.3%), effective 14 examples (18.7%), invalid 3 examples (4.0%), total effective rate 96.0%; Matched group 75 examples, wherein cure 29 examples (38.7%), effective 31 examples (41.3%), invalid 15 examples (20.0%) total effective rate 80.0%.Two groups of cure rates, total effective rates have significant difference, have comparability.(P＜0.05)。
(2) treatment a course for the treatment of after two groups of serum bilirubins be down to normal required time and sleep quality: treatment group serum bilirubin is down to normal time average out to 5.0 days; To group group average out to 8.0 days; Treatment group 55 examples of having slept, matched group 30 examples.
The specific embodiment
Embodiment mono-: take Herba Solidaginis 18g, Herba desmodii microphylli 14g, Radix Rosae Platyphyllae 12g, Herba Abri 11g, Herba seu Radix Calanthes 13g, Herba Desmodii Styracifolii 16g, Radix Curcumae 14g, adding water 5500ml soaks, slow fire is fried, extracting juice 5000ml, it is suitable to be watered to temperature, children's is embraced into foam washing wherein 15 minutes, and clear water rinses 1 time.
Embodiment bis-: take Herba Solidaginis 20g, Herba desmodii microphylli 15g, Radix Rosae Platyphyllae 10g, Herba Abri 9g, Herba seu Radix Calanthes 16g, Herba Desmodii Styracifolii 15g, Radix Curcumae 13g, adding water 5500ml soaks, slow fire is fried, extracting juice 5000ml, it is suitable to be watered to temperature, children's is embraced into foam washing wherein 15 minutes, and clear water rinses 1 time.
Embodiment tri-: take Herba Solidaginis 15g, Herba desmodii microphylli 13g, Radix Rosae Platyphyllae 13g, Herba Abri 14g, Herba seu Radix Calanthes 7g, Herba Desmodii Styracifolii 18g, Radix Curcumae 15g, adding water 5500ml soaks, slow fire is fried, extracting juice 5000ml, it is suitable to be watered to temperature, children's is embraced into foam washing wherein 15 minutes, and clear water rinses 1 time.
Claims (1)
1. treat an external washout with traditional Chinese herbs agent for neonatal jaundice, it is characterized in that this external washout with traditional Chinese herbs agent made by the Chinese medicine of following weight: Herba Solidaginis 18g, Herba desmodii microphylli 14g, Radix Rosae Platyphyllae 12g, Herba Abri 11g, Herba seu Radix Calanthes 13g, Herba Desmodii Styracifolii 16g, Radix Curcumae 14g.
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| CN103394032B true CN103394032B (en) | 2014-07-30 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102727637A (en) * | 2012-06-19 | 2012-10-17 | 刘萍 | Traditional Chinese medicine soaking and washing liquid used for treating neonatal jaundice |
| CN103007191A (en) * | 2012-11-23 | 2013-04-03 | 邹洪胜 | Chinese medicinal composition for treating jaundice |
| CN103169922A (en) * | 2013-02-25 | 2013-06-26 | 张艳英 | Traditional Chinese medicine for treating pathologic jaundice of neonate and preparation method thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102727637A (en) * | 2012-06-19 | 2012-10-17 | 刘萍 | Traditional Chinese medicine soaking and washing liquid used for treating neonatal jaundice |
| CN103007191A (en) * | 2012-11-23 | 2013-04-03 | 邹洪胜 | Chinese medicinal composition for treating jaundice |
| CN103169922A (en) * | 2013-02-25 | 2013-06-26 | 张艳英 | Traditional Chinese medicine for treating pathologic jaundice of neonate and preparation method thereof |
Non-Patent Citations (6)
| Title |
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| 中医药防治新生儿黄疸研究进展;陶钧等;《中医儿科杂志》;20100115;第6卷(第01期);50-52 * |
| 中药水疗干预新生儿黄疸的研究进展;周建平等;《中国误诊学杂志》;20111115;第11卷(第32期);7835-7836 * |
| 中西医治疗新生儿黄疸的研究进展;吴肖妮等;《中医儿科杂志》;20130525;第9卷(第3期);52-55 * |
| 吴肖妮等.中西医治疗新生儿黄疸的研究进展.《中医儿科杂志》.2013,第9卷(第3期),52-55. |
| 周建平等.中药水疗干预新生儿黄疸的研究进展.《中国误诊学杂志》.2011,第11卷(第32期),7835-7836. |
| 陶钧等.中医药防治新生儿黄疸研究进展.《中医儿科杂志》.2010,第6卷(第01期),50-52. |
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