CN102727637A - Traditional Chinese medicine soaking and washing liquid used for treating neonatal jaundice - Google Patents
Traditional Chinese medicine soaking and washing liquid used for treating neonatal jaundice Download PDFInfo
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- CN102727637A CN102727637A CN2012102221635A CN201210222163A CN102727637A CN 102727637 A CN102727637 A CN 102727637A CN 2012102221635 A CN2012102221635 A CN 2012102221635A CN 201210222163 A CN201210222163 A CN 201210222163A CN 102727637 A CN102727637 A CN 102727637A
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- 239000003814 drug Substances 0.000 title claims abstract description 24
- 239000007788 liquid Substances 0.000 title claims abstract description 20
- 238000005406 washing Methods 0.000 title claims abstract description 16
- 206010023138 Jaundice neonatal Diseases 0.000 title claims abstract description 15
- 201000006346 Neonatal Jaundice Diseases 0.000 title claims abstract description 15
- 238000002791 soaking Methods 0.000 title abstract 5
- 210000000582 semen Anatomy 0.000 claims description 8
- 241001257016 Platyphylla Species 0.000 claims description 2
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 abstract description 24
- 210000004185 liver Anatomy 0.000 abstract description 14
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- 239000008280 blood Substances 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 3
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- 230000003860 sleep quality Effects 0.000 abstract description 2
- 210000002784 stomach Anatomy 0.000 abstract description 2
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 2
- 244000236521 Bupleurum rotundifolium Species 0.000 abstract 1
- 235000015221 Bupleurum rotundifolium Nutrition 0.000 abstract 1
- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 241000522190 Desmodium Species 0.000 abstract 1
- 241000184329 Evolvulus Species 0.000 abstract 1
- 241000121190 Lonchura striata Species 0.000 abstract 1
- 241000972673 Phellodendron amurense Species 0.000 abstract 1
- 241001499733 Plantago asiatica Species 0.000 abstract 1
- 240000001341 Reynoutria japonica Species 0.000 abstract 1
- 235000018167 Reynoutria japonica Nutrition 0.000 abstract 1
- 235000003657 Solidago canadensis Nutrition 0.000 abstract 1
- 244000197975 Solidago virgaurea Species 0.000 abstract 1
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- 230000003213 activating effect Effects 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 238000002474 experimental method Methods 0.000 abstract 1
- 210000003608 fece Anatomy 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000004383 yellowing Methods 0.000 abstract 1
- 206010023126 Jaundice Diseases 0.000 description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 230000001737 promoting effect Effects 0.000 description 9
- 208000004880 Polyuria Diseases 0.000 description 6
- 230000035619 diuresis Effects 0.000 description 6
- 210000000232 gallbladder Anatomy 0.000 description 5
- 210000003491 skin Anatomy 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 210000003786 sclera Anatomy 0.000 description 4
- 239000012467 final product Substances 0.000 description 3
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- 238000007920 subcutaneous administration Methods 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
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- 208000021130 Bilirubin encephalopathy Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine soaking and washing liquid used for treating neonatal jaundice. Neonatal jaundice is caused by intrinsic dampness evil in the spleen and stomach. The liver fails to maintain the normal flow of qi, and the bile spills, such that a yellowing phenomenon appears. Aiming at the problem, the medicine liquid provided by the invention adopts traditional Chinese medicines with heat clearing, dampness eliminating, liver soothing, qi regulating, stagnation eliminating, stasis removing, blood activating, and blood stasis removing functions, such as alsine-like evolvulus herb, common goldenrod herb, society finch, fodder vetch herb, amur corktree bark, Asiatic plantain seed, snowbelleaf tickclover herb, trogopterus dung, polygonum cuspidatum, Chinese thorowax root, and immature tangerine fruit. The traditional Chinese medicines are prepared into the soaking and washing liquid, and the liquid is used for soaking and washing neonate body surface. As a result of clinical experiments, a markedly effective rate and a total effective rate respectively reach 64.3% and 97.1%. The rates are substantially better than a control group. With the liquid, the time spent for reducing serum bilirubin to a normal value is substantially shorter than that of the control group, and sleep quality is better than that of the control group. The treatment method is simple, and the cost is low. Therefore, the traditional Chinese medicine soaking and washing liquid is worthy of clinical application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine bubble washing liquid of treating neonatal jaundice.
Background technology
Neonatal jaundice is UDC, how after birth, occurred in 2～4 days, and be the neonate common sympton in period, because the metabolic characteristics of neonatal bilirubin have 50% term infant and 80% premature infant the naked eyes jaundice can occur approximately.Clinical jaundice is divided into physiologic jaundice and pathological jaundice, as treats the untimely bilirubin encephalopathy that causes, make the central nervous system impaired, serious threat neonate health and lives.Treatment neonatal jaundice method is more, and like simple blue light illumination, oral western medicine, Chinese medicine, herbal enema etc., neonate oral drugs is difficulty relatively, and it is big to add the oral drugs side effect, has brought certain difficulty for treatment neonate treatment jaundice.The external washout with traditional Chinese herbs agent has overcome the difficulty of neonate oral drugs, and easy to operation effective, is treatment and early intervention treatment neonatal jaundice efficient ways.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine bubble washing liquid of treating neonatal jaundice, neonatal jaundice belongs to Chinese medicine " pregnant jaundice " category, and main cause is because impression is damp and hot; Stagnation of cold-damp, the alluvial jaundice, pathogenesis is to accumulate in the taste damp; The liver failing to maintain the normal flow of QI, the excessive and jaundice that arrives of bile, it is thin tender according to neonatal skin that the Chinese medicine bubble is bathed mechanisms of therapeutic action; Body surface area is big, and medicine is to see through the physiological characteristics of skin absorbs.The Chinese traditional treatment jaundice is the rule of treatment with disappear stagnant, blood circulation promoting and blood stasis dispelling of clearing away heat-damp and promoting diuresis, liver-smoothing, qi-regulating, eliminating stagnation.
The objective of the invention is to realize that through following technical scheme the Chinese medicine of this treatment neonatal jaundice steeps washing liquid and processed by following parts by weight of Chinese traditional medicine: Herba Evolvuli Alsinoides 12-15 part, Herba Solidaginis 12-15 part, Radix Rosae Platyphyllae 12-15 part, Herba Viviae Sativae 12-15 part, Cortex Phellodendri 15-20 part, Semen Plantaginis 20-25 part, Herba Desmodii Styracifolii 15-20 part, Oletum Trogopterori 12-15 part, Rhizoma Polygoni Cuspidati 15-20 part, Radix Bupleuri 12-15 part, Pericarpium Citri Reticulatae Viride 10-13 part.
Preferably, 14 parts in Herba Evolvuli Alsinoides, 14 parts of Herba Solidaginiss, 14 parts of Radix Rosae Platyphyllaes, 14 parts of Herba Viviae Sativaes, 18 parts of Cortex Phellodendris, 22 parts of Semen Plantaginiss, 18 parts of Herba Desmodii Styracifoliis, 13 parts of Oletum Trogopteroris, 18 parts of Rhizoma Polygoni Cuspidati, 13 parts of Radix Bupleuri, 12 parts on Pericarpium Citri Reticulatae Viride.
Method for preparing: water is put in medicine-feeding soaked, use slow fire fried then, filter fried medicinal liquid and be treatment neonatal jaundice Chinese medicine bubble washing liquid.
In the side: Herba Evolvuli Alsinoides: go into liver,spleen,kidney three warps: clearing away heat-damp and promoting diuresis; The subcutaneous ulcer of harnessing the Yellow River, stranguria with turbid discharge.
Herba Solidaginis: go into liver, gallbladder meridian; Wind and heat dispersing, subduing swelling and detoxicating; Control laryngopharynx swelling and pain, jaundice.
Radix Rosae Platyphyllae: return the liver and gall warp; The subcutaneous ulcer of harnessing the Yellow River, mass in the abdomen.
Herba Viviae Sativae: go into the heart, liver, spleen three warps; Clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, clearing away heart-fire for tranquillization, cooling blood for hemostasis.
Cortex Phellodendri; Return kidney, bladder, large intestine channel; Heat clearing and damp drying, eliminating fire and detoxication, reducing the asthenic fever.
Semen Plantaginis: return kidney, liver, lung meridian; Relieving stranguria by diuresis, dampness removing antidiarrheal, removing heat from the lung and dissipating phlegm.
Herba Desmodii Styracifolii: return liver, gallbladder, kidney, urinary bladder channel; Relieving stranguria by diuresis, dampness removing jaundice eliminating, removing toxic substances and promoting subsidence of swelling.
Oletum Trogopterori: return Liver Channel; Promoting blood circulation and stopping pain, removing stasis to stop bleeding.
Rhizoma Polygoni Cuspidati: return liver, gallbladder, lung meridian; Promoting blood circulation and stopping pain, clearing away heat-damp and promoting diuresis, detoxifcation, preventing phlegm from forming and stopping coughing.
Radix Bupleuri: GUIXIN envelope, liver, gallbladder, tri-jiao channel; Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.
Pericarpium Citri Reticulatae Viride: return liver, gallbladder, stomach warp; Soothing the liver dispelling the stagnated QI, eliminating stagnation disappears stagnant.
Clinical data
1, physical data neonatal jaundice 140 examples of 2～November in 2009 being in hospital in my section, male 82 examples, women 58 examples, age in days 2～23 days, body weight 2750～4600g.Be divided into treatment at random and organize 70 examples, matched group 70 examples.Two groups of ages, sex, body weight, state of an illness compare, and difference does not have significance meaning (all P＞0.05).
2,1. diagnostic criteria jaundice occurred in 2～3 days in term infant birth back, increased the weight of in 4～5 days, and 1～2 week disappeared, serum bilirubin 2～12mg/dl, and whole body is all right, does not have other clinical symptoms.2. morning, heavier, the continuity of disappearing, serum bilirubin≤12mg/dl, speed＜5mg/dl that every day, serum bilirubin rose appear in premature infant, dehydration or hungry person's jaundice.
3, Therapeutic Method treatment group is used Chinese medicine bubble washing liquid of the present invention, and bubble is washed 1 time/d 15min/ time; The conventional western medical treatment of matched group+jaundice eliminating oral liquid.Two groups equal 5 days be a course of treatment.
4, criterion of therapeutical effect is cured: skin, mucosa and sclera jaundice disappear basically, serum bilirubin＜100 μ mol/L; Effectively: skin, mucosa and sclera jaundice obviously before alleviate, serum bilirubin 100～205 μ mol/L; Invalid: skin, mucosa and sclera jaundice do not have and alleviate serum bilirubin＞205 μ mol/L.
Observation index: serum bilirubin is reduced to normal required time; Sleep: sleep＞4h is for to sleep continuously; Sleep＜1h is poor for sleep continuously.
5, therapeutic outcome (1) treatment is added up curative effect after a course of treatment.70 examples are organized in treatment, produce effects 45 examples (64.3%) wherein, effective 23 examples (32.9%), invalid 2 examples (2.9%), total effective rate 97.1%; Matched group 70 examples, produce effects 25 examples (35.7%) wherein, effective 32 examples (45.7%), invalid 13 examples (18.6%) total effective rate 81.4%.Two groups of obvious effective rates, total effective rates have significant difference (P＜0.05).
(2) two groups of serum bilirubins are reduced to normal required time and sleep quality after treatment course of treatment: treatment group serum bilirubin was reduced to the normal time average out to 5.0 days; To group group average out to 8.0 days; Treatment group sleep 38 examples, matched group 21 examples.
Model case: patient, woman, 6 ages in days.Being born sclera and xanthochromia both occurred in back 2 days, suck the breast can, big loose stool is green.The equal serum bilirubin 162mg/dl of lining used Chinese medicine bubble washing liquid of the present invention 5 days, and jaundice is moved back to the greatest extent, and stool transfers yellow loose stool, serum bilirubin 0.8mg/dl to.
The specific embodiment
Embodiment one: take by weighing Herba Evolvuli Alsinoides 14g, Herba Solidaginis 14g, Radix Rosae Platyphyllae 14g, Herba Viviae Sativae 14g, Cortex Phellodendri 18g, Semen Plantaginis 22g, 18 parts of Herba Desmodii Styracifoliis, Oletum Trogopterori 13g, Rhizoma Polygoni Cuspidati 18g, Radix Bupleuri 13g, Pericarpium Citri Reticulatae Viride 12g.1 dose/day of lotion adds water 5500ml and soaks, and slow fire is fried, extracting juice 5000ml, and it is suitable to convert water to temperature, children's is embraced into wherein steeping washed 10 minutes, and flushing with clean water gets final product for 1 time.
Embodiment two: take by weighing Herba Evolvuli Alsinoides 12g, Herba Solidaginis 12g, Radix Rosae Platyphyllae 12g, Herba Viviae Sativae 12g, Cortex Phellodendri 15g, Semen Plantaginis 20g, 15 parts of Herba Desmodii Styracifoliis, Oletum Trogopterori 12g, Rhizoma Polygoni Cuspidati 15g, Radix Bupleuri 12g, Pericarpium Citri Reticulatae Viride 10g.1 dose/day of lotion adds water 5500ml and soaks, and slow fire is fried, extracting juice 5000ml, and it is suitable to convert water to temperature, children's is embraced into wherein steeping washed 10 minutes, and flushing with clean water gets final product for 1 time.
Embodiment three: take by weighing Herba Evolvuli Alsinoides 15g, Herba Solidaginis 15g, Radix Rosae Platyphyllae 15g, Herba Viviae Sativae 15g, Cortex Phellodendri 20g, Semen Plantaginis 25g, 20 parts of Herba Desmodii Styracifoliis, Oletum Trogopterori 15g, Rhizoma Polygoni Cuspidati 20g, Radix Bupleuri 15g, Pericarpium Citri Reticulatae Viride 13g.1 dose/day of lotion adds water 5500ml and soaks, and slow fire is fried, extracting juice 5000ml, and it is suitable to convert water to temperature, children's is embraced into wherein steeping washed 10 minutes, and flushing with clean water gets final product for 1 time.
Claims (2)
1. a Chinese medicine bubble washing liquid of treating neonatal jaundice is characterized in that this Chinese medicine steeps washing liquid and processed by following parts by weight of Chinese traditional medicine: Herba Evolvuli Alsinoides 12-15 part, Herba Solidaginis 12-15 part, Radix Rosae Platyphyllae 12-15 part, Herba Viviae Sativae 12-15 part, Cortex Phellodendri 15-20 part, Semen Plantaginis 20-25 part, Herba Desmodii Styracifolii 15-20 part, Oletum Trogopterori 12-15 part, Rhizoma Polygoni Cuspidati 15-20 part, Radix Bupleuri 12-15 part, Pericarpium Citri Reticulatae Viride 10-13 part.
2. a kind of Chinese medicine bubble washing liquid of treating neonatal jaundice according to claim 1 is characterized in that this Chinese medicine steeps washing liquid and processed by following parts by weight of Chinese traditional medicine: 14 parts in Herba Evolvuli Alsinoides, 14 parts of Herba Solidaginiss, 14 parts of Radix Rosae Platyphyllaes, 14 parts of Herba Viviae Sativaes, 18 parts of Cortex Phellodendris, 22 parts of Semen Plantaginiss, 18 parts of Herba Desmodii Styracifoliis, 13 parts of Oletum Trogopteroris, 18 parts of Rhizoma Polygoni Cuspidati, 13 parts of Radix Bupleuri, 12 parts on Pericarpium Citri Reticulatae Viride.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210222163.5A CN102727637B (en) | 2012-06-19 | 2012-06-19 | Traditional Chinese medicine soaking and washing liquid used for treating neonatal jaundice |
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| CN201210222163.5A CN102727637B (en) | 2012-06-19 | 2012-06-19 | Traditional Chinese medicine soaking and washing liquid used for treating neonatal jaundice |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103169922A (en) * | 2013-02-25 | 2013-06-26 | 张艳英 | Traditional Chinese medicine for treating pathologic jaundice of neonate and preparation method thereof |
| CN103394032A (en) * | 2013-07-20 | 2013-11-20 | 刘萍 | Chinese medicinal external lotion for treating neonatal jaundice |
| CN108578635A (en) * | 2018-04-25 | 2018-09-28 | 杭州市红十字会医院 | A kind of newborn's Chinese medicine removing jaundice shower cream and preparation method thereof |
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| CN101744954A (en) * | 2009-12-29 | 2010-06-23 | 谭友民 | Medicine for internally treating icteric hepatitis |
| CN102178788A (en) * | 2011-04-26 | 2011-09-14 | 刘明述 | Chinese medicinal composition for reducing transaminase and jaundice and preparation method thereof |
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2012
- 2012-06-19 CN CN201210222163.5A patent/CN102727637B/en active Active
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| CN101744954A (en) * | 2009-12-29 | 2010-06-23 | 谭友民 | Medicine for internally treating icteric hepatitis |
| CN102178788A (en) * | 2011-04-26 | 2011-09-14 | 刘明述 | Chinese medicinal composition for reducing transaminase and jaundice and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103169922A (en) * | 2013-02-25 | 2013-06-26 | 张艳英 | Traditional Chinese medicine for treating pathologic jaundice of neonate and preparation method thereof |
| CN103169922B (en) * | 2013-02-25 | 2014-05-14 | 张艳英 | Traditional Chinese medicine for treating pathologic jaundice of neonate and preparation method thereof |
| CN103394032A (en) * | 2013-07-20 | 2013-11-20 | 刘萍 | Chinese medicinal external lotion for treating neonatal jaundice |
| CN103394032B (en) * | 2013-07-20 | 2014-07-30 | 宋丽峰 | Chinese medicinal external lotion for treating neonatal jaundice |
| CN108578635A (en) * | 2018-04-25 | 2018-09-28 | 杭州市红十字会医院 | A kind of newborn's Chinese medicine removing jaundice shower cream and preparation method thereof |
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