CN103393915B - 一种治疗干眼症的中药制剂 - Google Patents

一种治疗干眼症的中药制剂 Download PDF

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CN103393915B
CN103393915B CN201310322307.9A CN201310322307A CN103393915B CN 103393915 B CN103393915 B CN 103393915B CN 201310322307 A CN201310322307 A CN 201310322307A CN 103393915 B CN103393915 B CN 103393915B
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CN103393915A (zh
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房进彩
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Sichuan Eagle Group Co ltd
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Abstract

本发明公开了一种治疗干眼症的中药制剂。中医认为干眼症属中医学“白涩证”、“神水将枯”范畴，泪为肝液，肝肾阴虚，虚火上炎，津液亏损，或郁热化火，上攻于目，灼津耗液，从而致泪液减。为此，本发明选择中药枸骨根、野扇花果、密蒙花、竹根七、天门冬、白芍、白花夏枯草、玄参、桑叶，水煎成汤剂，经临床试验，总有效率达到96.0％，明显优于对照组。

Description

一种治疗干眼症的中药制剂
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗干眼症的中药制剂。 
背景技术
干眼症是指任何原因引起泪液质或量及动力学的异常，导致泪膜不稳定和眼表面的异常，并伴有眼部不适症状或眼表组织病变为特征的多种疾病总称，亦称角结膜干燥症，是眼科常见的眼表疾病之一，其发病率逐年增高，且年龄趋向年轻化，严重的干眼症将导致角膜表面磨损、丝状角膜炎和角膜溃疡。最终发生角膜混浊和视力丧失等严重后果。 
发明内容
本发明的目的是提供一种治疗干眼症的中药制剂。中医认为干眼症属中医学“白涩证”、“神水将枯”、“神水枯痒”、“燥证”范畴，泪为肝液，肝肾阴虚，虚火上炎，津液亏损，或郁热化火，上攻于目，灼津耗液，从而致泪液减。 
本发明的目的是通过以下技术方案实现的，该治疗干眼症的中药制剂由以下重量份的中药制成：枸骨根10-25份、野扇花果15-30份、密蒙花10-15份、竹根七5-15份、天门冬7-13份、白芍13-18份、白花夏枯草15-25份、玄参10-14份、桑叶12-18份。 
优选的，枸骨根18份、竹根七10份、天门冬10份、野扇花果 23份、白芍17份、密蒙花13份、白花夏枯草20份、玄参12份、桑叶15份。 
制备方法将上述中药水煎制成汤剂。 
方中：枸骨根、野扇花果、密蒙花补肝肾，清风热，养肝安神，明目；竹根七、天门冬、玄参滋阴泻火，活血解毒，养阴润燥，清火生津，清热凉血；白芍、白花夏枯草、桑叶养血调经，平肝止痛，疏散风热，清肺润燥，平肝明目。 
临床资料 
1、一般资料所选病例为2008年12月～2009年12月就诊于我院眼科门诊的干眼症患者100例，200只眼睛，随机分为治疗组和对照组，治疗组50例，其中男24例，女26例，年龄23～65岁，平均(44.35±12.30)岁；对照组50例，其中男22例，女28例，年龄25～70岁，平均(45.47±13.32)岁；两组患者无全身免疫性疾病。两组性别、年龄、病程等均无统计学差异(P＞0.05)，具有可比性。 
2、诊断标准参照国家中医药管理局颁布的行业标准《中医病证诊断疗效标准》：①眼干涩、磨痛、畏光，可伴有口鼻干燥；②目珠干燥失却莹润光泽，白睛微红，黑睛生翳，眵多黏稠；③泪液分泌量测定，多次Schirmer I法少于10mm/5min，角膜荧光素染色试验阳性。 
3、治疗方法治疗组患者服用本发明所述的中药制剂，即称取枸骨根18g、竹根七10g、天门冬10g、野扇花果23g、白芍17g、密蒙花13g、白花夏枯草20g、玄参12g、桑叶15g，水煎制成汤剂，每日一剂，早晚2次分服；对照组局部点美国ALCON公司的泪然滴 眼液，每日3～6次。两组均30天为一个疗程。 
4、疗效标准参照国家中医药管理局颁布的行业标准《中医病证诊断疗效标准》。治愈：症状消失，角膜染色消退，Schirmer I试验多次测定大于10mm/5mim；好转：症状减轻，角膜染色减少，SchirmerI试验多次测定泪液分泌量有所增加；未愈：症状无改善，角膜染色无变化或增多，SchirmerI试验多次测定泪液分泌量未增。 
5、治疗结果两组治疗一个疗程后疗效比较见表1。 
表1两组治疗一个疗程后疗效比较 
与对照组治疗后比较，①P＜0.05 
两组比较治疗组治愈率、总有效率明显优于对照组，具有可比性，差异有显著性意义(P＜0.05)。 
具体实施方式
实施例一：称取枸骨根18g、竹根七10g、天门冬10g、野扇花果23g、白芍17g、密蒙花13g、白花夏枯草20g、玄参12g、桑叶15g，将上述中药水煎制成汤剂。 
实施例二：称取枸骨根25g、竹根七15g、天门冬13g、野扇花果30g、白芍13g、密蒙花10g、白花夏枯草25g、玄参14g、桑叶12g，将上述中药水煎制成汤剂。 
实施例三：称取枸骨根10g、竹根七5g、天门冬7g、野扇花果15g、白芍18g、密蒙花15g、白花夏枯草15g、玄参10g、桑叶18g，将上述中药水煎制成汤剂。 

Claims (1)

1.一种治疗干眼症的中药制剂，其特征在于该中药制剂由以下重量的中药制成：枸骨根18g、竹根七10g、天门冬10g、野扇花果23g、白芍17g、密蒙花13g、白花夏枯草20g、玄参12g、桑叶15g，将上述中药水煎制成汤剂。
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CN104367627A (zh) * 2014-11-01 2015-02-25 王春磊 一种治疗肝肾亏虚型干眼症的中药制剂
CN104383352A (zh) * 2014-12-11 2015-03-04 崔合芳 一种治疗阴虚湿热型干眼症的中药制剂
CN104998108A (zh) * 2015-07-25 2015-10-28 庄迎春 一种治疗干眼症的中药组合物
CN105055947A (zh) * 2015-08-04 2015-11-18 庄迎春 一种治疗眼干的药物
CN105012525A (zh) * 2015-08-05 2015-11-04 刘雪梅 一种用于治疗干眼的中药制剂及制备方法

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CN102106977A (zh) * 2009-12-24 2011-06-29 孟繁英 外用防治眼病强健视力护眼药液
CN102145126B (zh) * 2011-04-13 2012-03-07 张铭连 治疗干眼症的药物组合物
CN102198227B (zh) * 2011-05-09 2012-07-25 王维萌 一种治疗阴虚型青光眼的中药制备方法

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