CN1033934A - Embolism extinguishing oral (liquid, sheet, electuary) method for making - Google Patents
Embolism extinguishing oral (liquid, sheet, electuary) method for making Download PDFInfo
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- CN1033934A CN1033934A CN 88108069 CN88108069A CN1033934A CN 1033934 A CN1033934 A CN 1033934A CN 88108069 CN88108069 CN 88108069 CN 88108069 A CN88108069 A CN 88108069A CN 1033934 A CN1033934 A CN 1033934A
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Abstract
The production technology of the oral embolism extinguishing of a kind of Chinese patent medicine (liquid, sheet, electuary).
According to the embolism extinguishing oral (liquid, sheet, electuary) that " BUYANG HUANWU TANG " prescription of the well-known doctor of China Qing Dynasty Wang Qingren is made, be that a kind of modify-water decoction is the method for precipitate with ethanol behind the decocting.Medicine after it will decoct in vacuo concentrates, and adds ethanol precipitation again and adds the dilution of distillation water with sucrose then and get final product.Lamellar or electuary are drying and crushing again behind the precipitate with ethanol, add blank granule, magnesium stearate sugar-coat or add powdered sugar and granulate and get final product.
Description
The production technology of a kind of Chinese patent medicine embolism extinguishing oral (liquid, sheet, electuary).
Hemiplegia, deflective mouth and eye, the language plug that causes owing to reasons such as apoplexy at present is puckery, slobbering, lower limb flaccidity are useless, frequent micturition or patient that to lose that disease be can't help, the tongue the lung-pulse is slow etc. sick are more, but a lot of medicine does not all have tangible curative effect to above-mentioned disease patient.These diseases are brought great misery and inconvenience to patient and family members etc." BUYANG HUANWU TANG " prescription of the well-known doctor of China Qing Dynasty Wang Qingren has certain curative effect to treating above-mentioned disease, and it is a kind of decoction Chinese medicine.Because the decoction of decoction is cumbersome, this is difficult to accomplish to some handicapped patients, and the active ingredient ratio is few in the decoction, and inconvenience is stored, and taste is very bitter.
The objective of the invention is in the development based on inheritance motherland traditional medicine treatment prescription to above-mentioned condition of illness, the method that adopts suitability for industrialized production is made its Chinese herbal medicine the Chinese Traditional Medicines of forms such as aqueous, lamellar, electuary.
The present invention chooses raw materials such as Radix Astragali 60g, Radix Angelicae Sinensis 60g, Radix Paeoniae Rubra 60g, Pheretima 30g, Rhizoma Chuanxiong 30g, Semen Persicae 30g, Flos Carthami 30g earlier roguing, removes foreign body, cuts broken then.Be put in then and add water in the decoction pot and do not have 10 centimeters of powder, approximately after half an hour medical material expansion amount of makeup water still make water there be not 10 centimeters of powder.Be heated to and boil 1.5 hours, collect medicinal liquid and store,, decoct medicinal liquid with three times again and merge then respectively according to decocting last time twice each 1 hour.
Decoction liquor is put into vacuum concentration pan (or interlayer evaporation boiler) concentrates, make proportion reach 1.18-1.22(50 ℃ of heat and survey in vacuum 700-760mm/mmHg) promptly.
Concentrated solution (15～40 ℃) is added 96% ethanol to be contained alcohol amount and reaches about 75% to making.The limit edged does not stop to stir, and leaves standstill then 24 hours.
To leave standstill liquid and filter, and get supernatant ethanol and reclaim in the pot, and reclaim ethanol and promptly do not get embolism extinguishing oral liquid clear paste to there being the alcohol flavor.In clear paste, add 30% sucrose promptly with sucrose 90g heating for dissolving, put cold filtration, add distillation water and be diluted to 300mL and adjust pH value at last, then medicinal liquid is poured into peace bottle encapsulation sterilization to 5.0-6.5.
Filter process is taked diluent to add filter paper pulp to stir evenly, with buchner funnel or sintered glass filter, be filtered to clear and bright repeatedly.
Oral of embolism extinguishing is that embolism extinguishing oral liquid clear paste 2000g is carried out vacuum drying again, takes out and pulverizes, and adds 80% alcohol granulation drying, adds blank granule, and it is an amount of to add magnesium stearate, and granulate, tabletting wrap faint yellow sugar-coat.
The embolism extinguishing oral granule is with embolism extinguishing oral liquid clear paste reconcentration, and other gets sucrose in 80 ℃ of dryings 4 hours, takes out and is ground into 80 order fine powders, is mixed and made into the soft material granulation drying at 1: 4.5 by the ratio of clear paste and sugar and gets final product.
Embolism extinguishing oral (liquid, sheet, electuary) relatively has the following advantages with traditional decoction: its patient that can save time, save trouble need not oneself boil medicine, easily store and can take at any time, owing to adopt the method for water decoction-alcohol sedimentation, remove the impurity in the decoction liquor, remain with effective constituent, thereby improved effective component content and reduced dosing, every gram is equivalent to crude drug 28 grams, and it is better that oral liquid is the peony outward appearance, the low patient who is suitable for different dosages of sheet electuary cost.Embolism extinguishing oral (liquid, sheet, electuary) is good through clinical trial result,, slobbering, lower limb flaccidity degree, frequent micturition puckery to QI invigorating, promoting blood circulation to remove obstruction in the collateral, apoplexy sequela, hemiplegia, deflective mouth and eye, language plug or the enuresis be can't help, the tongue the lung-pulse is slow etc. that symptom has obvious curative effects, effective percentage is more than 95%.
Claims (3)
1, the method for making of embolism extinguishing oral (liquid, sheet, electuary), embolism extinguishing oral (liquid, sheet, electuary) Main Ingredients and Appearance is decocted with water several times through chopping by the Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami and adjuvant to be made, and it is characterized in that:
A, embolism extinguishing oral liquid are that the medicinal liquid after decocting is several times merged, carry out vacuum concentration then, medicinal liquid after will concentrating again (under 15～40 ℃ of conditions) adds 96% ethanol and does not stop to stir to making the alcohol amount of containing reach 75%, after leaving standstill 24 hours, to leave standstill liquid and filter, and reclaim ethanol and medicinal liquid is condensed into clear paste, add 30% sucrose again, with the dilution of distillation water, stir evenly at last and transfer PH to 5.0～6.5 back fill sterilizations to get final product then;
B, oral of embolism extinguishing are with the clear paste after concentrating in the oral liquid, again through vacuum drying, take out and pulverize, and with 80% alcohol granulation, drying adds blank granule, adds an amount of granulate of magnesium stearate, tabletting, wrap faint yellow sugar-coat;
C, embolism extinguishing oral granule are that spissated clear paste concentrates again in the oral liquid, and other gets sucrose in 80 ℃ of dryings 4 hours, take out and are ground into 80 order fine powders, are mixed into soft material at 1: 4.5, the drying of granulating by the ratio of clear paste and sugar.
2, as the method for making of embolism extinguishing oral (liquid, sheet, electuary) as described in the claim 1., it is characterized in that evacuation vacuum available pot or interlayer evaporation boiler, vacuum is at 700-760mm/mmHg, and temperature is about 50 ℃.
3, as the method for making of the described embolism extinguishing of claim 1. oral (liquid, sheet, electuary), it is characterized in that: the clear paste proportion after concentrating is (50 ℃ of heat are surveyed) in 1.18～1.22 scopes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 88108069 CN1033934A (en) | 1988-11-28 | 1988-11-28 | Embolism extinguishing oral (liquid, sheet, electuary) method for making |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 88108069 CN1033934A (en) | 1988-11-28 | 1988-11-28 | Embolism extinguishing oral (liquid, sheet, electuary) method for making |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1033934A true CN1033934A (en) | 1989-07-19 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 88108069 Pending CN1033934A (en) | 1988-11-28 | 1988-11-28 | Embolism extinguishing oral (liquid, sheet, electuary) method for making |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1033934A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102145055A (en) * | 2011-03-30 | 2011-08-10 | 呼伦贝尔松鹿制药有限公司 | Sugar-free embolism eliminating oral liquid and preparation method thereof |
| CN103585315A (en) * | 2013-10-30 | 2014-02-19 | 孙玉珍 | Traditional Chinese medicinal preparation for treating deep venous thrombosis of lower limbs |
| CN103599214A (en) * | 2013-11-25 | 2014-02-26 | 三株福尔制药有限公司 | Probiotics fermented Xiaoshuan oral liquid and preparation method thereof |
| CN104547619A (en) * | 2015-01-09 | 2015-04-29 | 郑江红 | Traditional Chinese medicine for treating apoplexy sequela paralytic limbs and preparation method of traditional Chinese medicine |
-
1988
- 1988-11-28 CN CN 88108069 patent/CN1033934A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102145055A (en) * | 2011-03-30 | 2011-08-10 | 呼伦贝尔松鹿制药有限公司 | Sugar-free embolism eliminating oral liquid and preparation method thereof |
| CN102145055B (en) * | 2011-03-30 | 2013-04-03 | 呼伦贝尔松鹿制药有限公司 | Sugar-free embolism eliminating oral liquid and preparation method thereof |
| CN103585315A (en) * | 2013-10-30 | 2014-02-19 | 孙玉珍 | Traditional Chinese medicinal preparation for treating deep venous thrombosis of lower limbs |
| CN103585315B (en) * | 2013-10-30 | 2016-01-06 | 孙玉珍 | A kind of Chinese medicine preparation for the treatment of deep venous thrombosis of lower limbs |
| CN103599214A (en) * | 2013-11-25 | 2014-02-26 | 三株福尔制药有限公司 | Probiotics fermented Xiaoshuan oral liquid and preparation method thereof |
| CN103599214B (en) * | 2013-11-25 | 2015-08-19 | 三株福尔制药有限公司 | A kind of probiotics fermentation-type embolism extinguishing oral liquid and preparation method thereof |
| CN104547619A (en) * | 2015-01-09 | 2015-04-29 | 郑江红 | Traditional Chinese medicine for treating apoplexy sequela paralytic limbs and preparation method of traditional Chinese medicine |
| CN104547619B (en) * | 2015-01-09 | 2018-01-09 | 郑江红 | It is a kind of to be used to treat Chinese medicine of apoplexy sequelae hemiplegia of limb and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |